Abstract: This invention relates to recombinantly-expressed denosumab molecules and methods for modulating glycan profiles of denosumab molecules.

Abstract: A display apparatus and a splice display system are disclosed. The display apparatus includes: a lamp panel, which includes a circuit board and a plurality of light-emitting elements on the circuit board; and a mask on side of the plurality of light-emitting elements away from the circuit board, where the mask includes a plurality of light-transmitting parts corresponding to the plurality of light-emitting elements, an orthographic projection of each of the plurality of light-emitting elements on the circuit board is within an orthographic projection of a corresponding light-transmitting part on the circuit board, each of the plurality of light-transmitting parts includes a concave lens, and a surface of the concave lens close to the light-emitting element is a concave arc surface.

Abstract: A method includes tagging source PDK devices (SPDs) in a source-circuit design (SCD); generating a source design simulation database (SDSD) based on source design key performance indicator (KPI) simulation data of the SPDs in the SCD; generating a target process design kit (PDK) simulation database (TPSD) based on target design KPI simulation data of a plurality of target-PDK devices (TPDs); creating a matching table based on the SDSD and the TPSD; matching, based on the matching table, one or more TPDs from the TPSD with each SPD in the SDSD based on SPD KPIs; ranking the one or more TPDs matched from the TPSD with each SPD in the SDSD based on the SPD KPIs; and exchanging, based on a migration mapping table that includes a one-to-one relationship for TPDs to the SPDs in the SCD, one or more SPDs in the SCD with one-to-one relational TPDs.

Abstract: The embodiments of the disclosure relates to a method, apparatus, device and medium for information presentation, wherein the method includes: receiving an update instruction for a first text in a reader, the first text being a part of a target book content; and updating the first text based on the target book content, and in response to the first text meeting a predetermined condition, presenting recommendation information in a full screen mode in the reader; wherein the predetermined condition is determined based on text feature information of the first text. Using the above technical solution, during the updating of the text of the book content presented in the reader, the recommendation information can be presented in the full screen mode when it is determined that the text meets the predetermined condition based on the text feature information.

Abstract: The present invention provides a methionine adenosyltransferase 2A inhibitor. The structure of the methionine adenosyltransferase 2A inhibitor is as represented by general formula (I), and the definitions of substituents are as described in the specification. The present invention further provides a preparation method therefor. A compound represented by formula I provided by the present invention has significant methionine adenosyltransferase 2A inhibitory activity, and can be used in the treatment of diseases mediated by overexpression of methionine adenosyltransferase 2A.

Abstract: Disclosed are an electromagnet driving mechanism, an electromagnet driving assembly and a dual power automatic transfer switch. The electromagnet driving mechanism includes: a mechanism frame; a stationary core; a movable core, including a moving stroke between a first position away from the stationary core and a second position in contact with the stationary core, the moving stroke including an approaching stroke section; a coil, configured to generate a magnetic attraction force between the stationary core and the movable core upon being energized to drive the movable core to move towards the second position; a reset spring member; and a reset auxiliary assembly, including a push member and a reset auxiliary spring. The reset auxiliary assembly applies a reset auxiliary spring force to the movable core in the approaching stroke section through the push member.

Abstract: Methods and compositions for estimating one or more downhole qualities of a drilling apparatus by obtaining axial acceleration data. The axial acceleration data may be acquired by measuring an axial acceleration of a bottom hole assembly. The axial acceleration may then be used to estimate one or more of a downward weight on a drill bit of the drilling apparatus or a rate of penetration of the drill bit.

Abstract: A super junction structure includes a substrate, wherein the substrate has a first conductivity type. The super junction structure includes an epitaxial layer over the substrate, wherein the epitaxial layer has a second conductivity type opposite the first conductivity type. The super junction structure further includes a bury layer between the epitaxial layer and the substrate, wherein the bury layer has the second conductivity type. The super junction structure further includes a conductive pillar in the epitaxial layer, wherein the conductive pillar has the first conductivity type, sidewalls of the conductive pillar are angled with respect to a top-most surface of the epitaxial layer, a bottom surface of the conductive pillar is rounded, and a top-most surface of the conductive pillar is coplanar with the top-most surface of the epitaxial layer.

Abstract: A method and system for simultaneous quantitative multiparametric MRI are provided in the disclosure. The method includes: designing a magnetic resonance imaging (MRI) sequence which includes a signal excitation part, a shift gradient part, and a data acquisition part; generating training samples for a deep neural network according to the MRI sequence; training the deep neural network by using the training samples, to obtain a trained deep neural network; and reconstructing multiple magnetic-resonance parametric maps by using the trained deep neural network and k-space data acquired by the MRI sequence. The disclosure can implement quantitative multiparametric MRI, and can correct image distortions caused by magnetic field inhomogeneity.

Abstract: A double-balloon thrombolysis and thrombectomy device, comprising a catheter, an access sheath, and a hemostasis valve. The catheter comprises a base, a body, a first balloon, and a second balloon, the first balloon and the second balloon are sleeved over the body, the first balloon is located at a distal end of the body, and the second balloon is located at the proximal end of the first balloon; the base is connected to the proximal end of the body, and comprises a main connection port, a first connection port and a second connection port; the first balloon is connected to the first connection port, and the second balloon is connected to the second connection port; the surface of the second balloon is provided with a plurality of micropores; and the access sheath is sleeved over the catheter body, and connected to the catheter body through the hemostasis valve.

Abstract: A touch control method, a touch control circuit system, and a touch device, the touch device includes a plurality of touch electrodes, the touch control method includes: step S1, sending a scanning signal to the plurality of touch electrodes; step S2, acquiring first touch data and second touch data according to the scanning signal; and step S3, the touch device defining a plurality of touch nodes, each of the plurality of touch nodes corresponding to the first touch data and the second touch data, defining at least one target touch node according to a difference between the first touch data and the second touch data, and calculating a current touch position according to the first touch data and the second touch data of the at least one target touch node.

Abstract: A method for constructing a convolutional neural network model based on farmland images is applied in an electronic device. The method includes following steps: obtaining a number of farmland images of at least one farmland; obtaining a plurality of standard segmentation farmland images corresponding to each of the farmland images; dividing the farmland images and the standard segmentation farmland images into a training image set and a test image set; taking the farmland images and the standard segmentation farmland images in the training image set as input of a convolutional neural network, and constructing a convolutional neural network model based on the farmland images; and verifying the convolutional neural network model by using the farmland images in the test image set and the standard segmentation farmland images, and optimizing a plurality of parameters of the convolutional neural network model based on the farmland images.

Abstract: Methods, apparatus, and products for receiving measurements indicative of present value torque (TrqPv) currently being applied by a top drive to a drill string extending in a well that penetrates a subterranean formation, and releasing torque accumulated in the drill string by determining polarity of TrqPv and, in response to a manual or automatic trigger, causing the top drive to perform an unwinding operation in a direction opposite to the determined TrqPv polarity.

Abstract: The application describes a security inspection apparatus and a method of controlling the same. An example security inspection apparatus includes a body fixed in the field and an electromagnetic imaging device installed on the body. The electromagnetic imaging device includes a two-dimensional multi-input multi-output array panel, including at least one two-dimensional multi-input multi-output sub-array and a control circuit. Each two-dimensional multi-input multi-output sub-array includes transmitting antennas and receiving antennas, with the transmitting antennas and the transmitting antennas being arranged such that equivalent phase centers are arranged in a two-dimensional array. The electromagnetic imaging device further includes a signal processing device configured to reconstruct an image of an inspected object based on an echo signal received and a display device configured to display the reconstructed image of the inspected object.

Abstract: Embodiments of the present disclosure disclose a display panel, a display device, and a method for manufacturing the display panel. The display panel includes an array substrate, an anode layer, a pixel definition layer, a fence layer, and a cathode layer. The array substrate includes an lap layer, and the lap layer includes a lap portion. A first opening on the anode layer exposes the lap portion. The fence layer includes a fence portion, and the fence layer includes a fence portion extending along an edge of the second opening. In the present disclosure, lap effect between the cathode layer and the lap portion can be improved by setting the fence portion.

Abstract: This application provides a vapor generation device and a resistance heater for a vapor generation device. The vapor generation device includes a housing, where the housing is provided with: a chamber, extending between a proximal end and a distal end opposite to each other and configured to removably receive the aerosol generation product; a heating element, configured to heat the aerosol generation product received in the chamber; a keeping element, constructed to extend in an axial direction of the chamber and at least partially surround the chamber, where the keeping element defines a hollow region at least partially surrounding the chamber, and the heating element is kept in the hollow region; and an air channel, extending at least partially from the proximal end toward the distal end within the hollow region and keeping fluid communication with the chamber at a position close to the distal end.

Abstract: A motor controller to control rotational speed of an output shaft of an electric motor. The motor controller includes a proportional controller and a time-optimal controller. The proportional controller controls the rotational speed when a present rotational position of the shaft is between a target rotational position and a switching point, inclusively. The time-optimal controller controls the rotational speed when the present rotational position is not between the target rotational position and the switching point. Also introduced herein are aspects pertaining to determining the switching point in a manner that minimizes overshooting the target rotational position while maximizing expediency at which the target rotational position is reached.