Abstract: The present invention discloses an antibody drug conjugate that targets MSLN. The present invention also disclosed a method of making the antibody drug conjugate (ADC). The present invention further discloses a novel MSLN antibody or a functional fragment thereof comprising engineered heavy and light chains.

Abstract: Provided are a method of verifying process data of a display panel, a device, a storage medium, and a product, which relates to a field of process verification technology. The method of verifying the process data of the display panel includes: generating, based on design data of a process of the display panel, simulation process data for performing the process; performing, by using a process model, a simulation of performing the process based on the simulation process data; and verifying, by using a measurement model, whether the simulation process data is applicable to actual production based on the simulation. The process model is constructed based on actual process data generated in an actual manufacturing process of the display panel, and the measurement model is constructed based on actual process data and actual measurement data which are generated in the actual manufacturing process of the display panel.

Abstract: The present disclosure provides data processing methods and apparatuses, an electronic device and a storage medium. The method includes: obtaining a product sample set; obtaining combination features in specified dimensions of the product sample set by processing a second parameter based on a preset dimension reduction algorithm; obtaining influence scores respectively for the combination features in specified dimensions based on a first parameter and the combination features in specified dimensions; obtaining at least one combination feature ranked top by sorting the combination features based on the influence scores, and taking a raw parameter corresponding to the at least one combination feature as a cause of the product defect.

Abstract: A wireless transmission device for an MR imaging apparatus, including: a transmitting coupler with a transmitting coil array including one or more first transmitting coils arranged in a first local coil device and to transmit a first intermediate frequency signal, the first local coil device being located on a patient couch and below an examined portion of a subject, wherein the first intermediate frequency signal is generated based on a first magnetic resonance signal received by the first local coil device from the subject; and a first receiving coupler including a first receiving coil array, the first receiving coil array including one or more first receiving coils, located below a trajectory of the patient couch sliding over the magnetic resonance main body, and configured to receive the first intermediate frequency signal from the transmitting coil array in response to the transmitting coil array overlapping with the first receiving coil array.

Abstract: Disclosed is a draw-bar box-type quickly folding micro electric vehicle, comprising of a seat frame assembly (1) that is horizontally arranged, the top surface of which is provided with a foldable backrest. A pair of symmetrically arranged rear wheel assemblies (2) are arranged at a position, close to a rear of the vehicle, on the bottom surface of the seat frame assembly (1), and two vertically downward first connecting posts (101), which are provided near the front of the lower end of the seat frame assembly (1). A footrest assembly (4) is hinged to the lower ends of the two first connecting posts (101) through the first connecting assemblies (3). The footrest assembly (4) is arranged parallel to the seat frame assembly (1), and the plane of the footrest assembly (4) is lower than the plane of the seat frame assembly (1).

Abstract: A pixel circuit comprises a drive sub-circuit (101), writing sub-circuit (102), reset sub-circuit (103), voltage stabilizing sub-circuit (104), storage sub-circuit (105) and light emitting element. The drive sub-circuit is configured to provide a driving current to the light emitting element under control of signals of a first node (N1) and a second node (N2); the writing sub-circuit is configured to write a signal from a data signal terminal (Data) to N2 under control of signal of a scan signal terminal (Gate); the storage sub-circuit is configured to store a voltage of N1; the voltage stabilizing sub-circuit is configured to stabilize a voltage of an anode terminal of light emitting element through signal of a voltage stabilizing signal terminal (V1); the reset sub-circuit is configured to reset anode terminal of light emitting element under control of signal of Gate and reset N1 under control of signal of a reset control signal terminal (Reset).

Abstract: The present invention discloses a method and an apparatus for monitoring an elevator door-opening operation fault. The method includes: acquiring elevator control signals from a serial interface between an elevator controller and a control box by using a preset data acquisition device, wherein the elevator control signals include an elevator operation signal, an elevator door control signal, an elevator internal call signal and an elevator floor signal; monitoring whether there is an elevator door fault in the elevator based on the elevator operation signal, the elevator door control signal and the elevator floor signal; when there is the elevator door fault in the elevator and the elevator internal call signal is in a preset level state, determining that there is the elevator door-opening operation fault in the elevator. The present invention is lower in use cost and may be easily popularized and applied.

Abstract: Provided is a display panel. The display panel includes: a substrate including a light-transmitting display region and a conventional display region; a plurality of first pixel drive circuits, a plurality of first connecting lines, and a plurality of first light-emitting devices disposed in the conventional display region, wherein the first connecting line comprises a connection line part and a compensation part electrically connected to each other, the compensation part being configured to increase an area of the first connecting line; and a plurality of second pixel drive circuits disposed in the conventional display region, a plurality of second connecting lines disposed on the substrate, and a plurality of second light-emitting devices disposed in the light-transmitting display region.

Abstract: A mold for preparing large-size rare earth magnesium alloy ingot without tail shrinkage by back pressure plastic deformation includes a male mold, a female mold, a recoverable discard block and a back pressure plate connected with a pushing cylinder of the press machine. The female mold is provided with an upper mold cavity and a lower mold cavity, an upper part of the upper mold cavity is configured for placing blanks, the recoverable discard block and the male mold, and a lower part of the upper mold cavity is inclined inward to form an extrusion deformation area. The recoverable discard block is configured to be deformed to fill an extrusion deformation area and subsequently restored into the initial state of the recoverable discard block.

Abstract: A method for screening tobacco resistance against root-knot nematode based on intensive seedling production is provided. The method has two biological properties: inducing and stimulating the hatching of nematode eggs by host root exudates, and easily infecting the root cap elongation zone by hatched second-instar larvae. The second-instar larvae hatched by the root-knot nematode eggs are continuously inoculated. After that, under cultivating the infected tobacco seedlings in shallow water infiltrating and humidifying substrate, the created temperature, humidity and air permeability conditions are suitable for disease induction. After disease investigation, disease index is calculated, and the resistance of tested cultivars is evaluated according to the disease index. The method features simple operation, high selection efficiency, and high accuracy and reproducibility.

Abstract: A three degree of freedom hardware in loop simulation system and its working method are provided. A triaxial air-bearing turntable is installed on a support frame. An air bearing support seat provides high-pressure gas lubrication to make an air bearing hemisphere freely roll and rotate. An attitude control system is installed on a test platform, and the platform is placed on an adapter plate, which is placed above the hemisphere. A position limiting protection device has a position limiting ring, which is located below the adapter plate and surrounds the hemisphere. The movement of the ring prevents the platform from deviating beyond a set angle. An automatic leveling device is located below the side of the platform and a leveling device control box is installed on the platform.

Abstract: Methods of treating patients suffering from or exhibiting symptoms of mental, behavioral, and/or cognitive disorders with azelastine or a pharmaceutically acceptable salt of azelastine are disclosed.

Abstract: A pneumatic protection device for a triaxial air-bearing turntable and its working method are provided. The position limiting ring is located below the test platform and surrounds the air bearing hemisphere. Two first lifting support rods are connected below the position limiting ring, and each first lifting support rod is guided up and down, sliding on the linear bearing, which is fixed on the support frame. The lower part of the first lifting support rod is connected to the bearing mounting seat, and the bearing transmission shaft passes through the needle roller bearing. The two sides of the cylinder support bottom plate are connected and fixed on the support frame by connecting plate of a cylinder bottom plate. One end of the extending rod of the cylinder is connected to the cam connecting rod, and the two ends of the cam connecting rod are respectively connected to an irregular cam.

Abstract: Provided are the compound shown in general formula (I) or a stereoisomer, a deuterated compound, a solvate, a prodrug, a metabolite, a pharmaceutically acceptable salt, or co-crystal thereof, an intermediate thereof, and a use thereof in EGFR-related diseases such as cancer.

Abstract: A pneumatic protection device for a triaxial air-bearing turntable and its working method are provided. The position limiting ring is located below the test platform and surrounds the air bearing hemisphere. Two first lifting support rods are connected below the position limiting ring, and each first lifting support rod is guided up and down, sliding on the linear bearing, which is fixed on the support frame. The lower part of the first lifting support rod is connected to the bearing mounting seat, and the bearing transmission shaft passes through the needle roller bearing. The two sides of the cylinder support bottom plate are connected and fixed on the support frame by connecting plate of a cylinder bottom plate. One end of the extending rod of the cylinder is connected to the cam connecting rod, and the two ends of the cam connecting rod are respectively connected to an irregular cam.

Abstract: A three degree of freedom hardware in loop simulation system and its working method are provided. A triaxial air-bearing turntable is installed on a support frame. An air bearing support seat provides high-pressure gas lubrication to make an air bearing hemisphere freely roll and rotate. An attitude control system is installed on a test platform, and the platform is placed on an adapter plate, which is placed above the hemisphere. A position limiting protection device has a position limiting ring, which is located below the adapter plate and surrounds the hemisphere. The movement of the ring prevents the platform from deviating beyond a set angle. An automatic leveling device is located below the side of the platform and a leveling device control box is installed on the platform.

Abstract: A position limiting protection device for a test platform of a triaxial air-bearing turntable and its working method are provided. The triaxial air-bearing turntable is installed on a support frame and includes an air bearing support seat and an air bearing hemisphere. A test platform is placed on an adapter plate, which is placed above the air bearing hemisphere. The position limiting protection device includes three top rods and three annular parts, which are sequentially spaced to form a position limiting ring, the position limiting ring is located below the adapter plate and surrounds the air bearing hemisphere. The position limiting ring is spaced at a certain distance from the air bearing hemisphere, each annular part is fixed on a support frame, and the top rods are controlled to rise or fall to limit the movement of the test platform.

Abstract: A local coil control apparatus and a wireless local coil in a magnetic resonance imaging system. The apparatus includes a control signal transmission unit, the control signal transmission unit including a wireless receiving unit, a control signal extraction unit, and a control signal distribution unit. The wireless receiving unit receives, by a receiving antenna, a signal from a radiofrequency power amplifier emitted by a body coil of the MRI system, and transmits the signal to the control signal extraction unit; the control signal extraction unit, if it detects that the signal is background noise, generates a control signal instructing a local coil unit to switch to a tuned state, and, if it detects that the signal is broadband noise, generates a control signal instructing the local coil unit to switch to a detuned state, and distributes the control signal to each local coil unit through the control signal distribution unit.

Abstract: Pharmaceutical compositions comprising azelastine or a pharmaceutically acceptable salt of azelastine and alprazolam are disclosed. Methods of using the pharmaceutical compositions for treating patients suffering from one or more psychiatric disorders such as major depressive disorder, generalized anxiety disorder, panic disorder, agitation, social anxiety disorder, mild chronic depression, obsessive-compulsive disorder, premenstrual dysphoric disorder, seasonal affective disorder, dysthymia, childhood enuresis, bipolar disorder, posttraumatic stress disorder, sleep disorder related to anxiety, are also disclosed.

Abstract: A position detection apparatus including: an electromagnetic induction module configured to send to a mode triggering module an induced voltage signal generated due to a change in a magnetic field; a mode triggering module configured to output a preset trigger signal based on the induced voltage signal, the trigger signal corresponding to the induced voltage signal; and a signal generating module configured to generate an analog signal of a first mode corresponding to the induced voltage signal based on the received trigger signal, and send the analog signal of the first mode to an MR receiving module of an MRI system via an antenna module, so that: the MR receiving module judges whether the wireless squeeze ball has entered the interior of a body coil from outside a tubular body of the MRI system, based on the analog signal of the first mode.