Abstract: Substituted piperidines as BTK inhibitors, a preparation method thereof and a pharmaceutical application thereof. The substituted piperidines is a compound represented by a general formula (I) or a stereoisomer or a pharmaceutically acceptable salt thereof, and the substituted piperidines is used to treat BTK-related diseases such as tumors or autoimmune system diseases.

Abstract: The present invention discloses an antifreeze solution for food preservation, which comprises edible alcohol, propylene glycol, glycerin, calcium chloride, sodium chloride, amino acid, Antarctic krill protein hydrolysate with an average molecular weight of 50-100 KDa, surfactant and water, wherein the surfactant is one or more of phospholipid, Tween-20, Tween-60, and Tween-80; each component is food grade, and the mass percentage is expressed as follows: alcohol 15-30%, propylene glycol 10-30%, glycerol 2-15%, calcium chloride 1-10%, sodium chloride 3-10%, amino acid 0.1-0.15%, Antarctic krill protein hydrolysate 0.01-0.3%, surfactant 0.005-0.5%, and the balance is water. The antifreeze solution provided by the present invention can lower the freezing point, improve the heat transfer efficiency, inhibit the crystallization of antifreeze solution during the low temperature stirring process and improve the stability of the antifreeze solution.

Abstract: The disclosure relates to a hybrid orthogonal signal generator, a coil transmission front-end device, an RF coil system, and an MRI system. The hybrid orthogonal signal generator has an input end for receiving an RF signal, generates a hybrid orthogonal excitation signal on the basis of the RF signal, and provides the hybrid orthogonal excitation signal by means of an output end of the hybrid orthogonal signal generator, and comprises: a first conductor, arranged in a plane and being arc-shaped; and a second conductor having mutual inductance with the first conductor, the second conductor being connected between the input end and output end, wherein the first conductor and second conductor are parallel and arranged as mirror images of each other. The hybrid orthogonal signal generator has a compact size and is suitable for providing hybrid orthogonal excitation signals for an MRI system with a low field strength.

Abstract: Provided are a capacity expansion method and a capacity expansion system based on a dual-level list structure; a first level list of the dual-level list structure is a first-level array in which at least one array identifier is stored; a second level list of the dual-level list structure includes at least one second-level array, each second-level array stores data to be stored and corresponds to only one array identifier; the method includes: creating a new first-level array when an amount of data stored in the second-level array corresponding to each array identifier reaches a maximum value, a size of a new first-level array being greater than that of a current first-level array, and increasing a number of the second-level arrays; and copying the array identifier stored in the current first-level array to the new first-level array, and replacing the current first-level array with the new first-level array.

Abstract: A movable medical bed system may include a bed body and a power supply apparatus. The power supply apparatus may include an electrical energy receiver and an electrical energy transmitter. The electrical energy receiver is arranged on the bed body. The electrical energy transmitter is configured to be connected to a power source. The bed body is able to move to a working position relative to the electrical energy transmitter. When the bed body is located at the working position, the electrical energy receiver can engage in electrical energy transmission with the electrical energy transmitter without plugging-in. The movable medical bed system helps to make the supply of power more convenient.

Abstract: A MR wireless receiving coil device may include transmitters and receivers, the number of the receivers being equal to or greater than the number of the transmitters; each transmitter comprises: a coil group, an ADC group, two baseband low-pass filters, and an IQ modulation transmitter, wherein the coil group is connected to the ADC group, the ADC group is connected to the two baseband low-pass filters, the two baseband low-pass filters are connected to the IQ modulation transmitter, and the IQ modulation transmitter is provided with an antenna; each coil group contains one or more coils, and the maximum number of coils contained in each coil group is determined by available bandwidth, modulation scheme, and the bandwidth, sampling rate, and sampling accuracy of MR signal. The device and corresponding method advantageously allows an increase in the amount of magnetic resonance information transmitted per unit frequency band.

Abstract: A coil unit decoupling device and a magnetic resonance system. The device comprises a first phase shift circuit, a second phase shift circuit and a first crossover element, and the first crossover element is a capacitor or inductor, wherein a first connecting end of the first phase shift circuit is connected with a first port of a first coil unit, a second connecting end of the first phase shift circuit is connected with a first connecting end of the first crossover element, a first connecting end of the second phase shift circuit is connected with a first port of a second coil unit, a second connecting end of the second phase shift circuit is connected with a second connecting end of the first crossover element, and the first coil unit and the second coil unit are located in a magnetic resonance system.

Abstract: The present disclosure is directed to a coil unit decoupling apparatus and a magnetic resonance system. The apparatus is connected to a first coil unit and a second coil unit in a magnetic resonance system, and is configured to separate, by using a distribution characteristic of a spatial quadrature field between the first coil unit and the second coil unit, a Helmholtz signal and an anti-Helmholtz signal from signals received from the first coil unit and the second coil unit, so as to implement decoupling between the first coil unit and the second coil unit. This facilitates the complexity of decoupling coil units being reduced.

Abstract: A pharmaceutical composition containing the therapeutically active ingredients of azelastine or a pharmaceutically acceptable salt of azelastine and donepezil or rivastigmine or galantamine or a pharmaceutically acceptable salt of thereof is disclosed. A method of using the pharmaceutical composition for treating patients suffering from mental, behavioral, cognitive disorders is also disclosed.

Abstract: A control method is provided for controlling an electronic device having a main body. The control method may include: in response to the electronic device being activated and a primary battery being functionally connected to the main body of the electronic device, controlling the primary battery to power the electronic device; and in response to the electronic device being activated and the primary battery being functionally disconnected from the main body of the electronic device, controlling a backup battery to power the electronic device.

Abstract: Pharmaceutical compositions comprising azelastine or a pharmaceutically acceptable salt of azelastine and folic acid or folate, and/or salts, metabolites, or derivatives thereof are disclosed. Methods of using the pharmaceutical compositions for treating patients suffering from one or more psychiatric disorders or symptoms, such as major depressive disorder, generalized anxiety disorder, panic disorder, agitation, social anxiety disorder, mild chronic depression, obsessive-compulsive disorder, premenstrual dysphoric disorder, seasonal affective disorder, dysthymia, bipolar disorder, posttraumatic stress disorder, sleep disorder related to anxiety, are also disclosed.

Abstract: Pharmaceutical compositions comprising azelastine or a pharmaceutically acceptable salt of azelastine and melatonin are disclosed. Methods of using the pharmaceutical compositions for treating patients suffering from insomnia are also disclosed.

Abstract: A calling device of a MRI system may include a reader/writer and a call maker. The reader/writer can send a fixed-frequency electromagnetic wave. The call maker may include a main body, an antenna, an operating member, and an answering controller. The antenna can generate an induced current after receiving the fixed-frequency electromagnetic wave. The operating member can switch between first and second positions relative to the main body. The answering controller is configured such that: when the operating member is in the first position, a first radio-frequency signal is sent through the antenna with energy obtained from the induced current generated by the antenna, and when the operating member is in the second position, a second radio-frequency signal is sent through the antenna with energy obtained from the induced current generated by the antenna. The reader/writer can send different prompt signals according to the first and second radio-frequency signals.

Abstract: Pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt of azelastine, and methylcobalamin are disclosed. Methods of using the pharmaceutical compositions for treating patients with Alzheimer's disease or Parkinson's disease are also disclosed.

Abstract: Pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt of azelastine, and methylcobalamin are disclosed. Methods of using the pharmaceutical compositions for treating patients with Alzheimer's disease or Parkinson's disease are also disclosed.

Abstract: The disclosure relates to a magnetic resonance imaging device configured to exert a high-frequency electromagnetic field on an object under test in a static magnetic field and to reconstruct an image based on magnetic resonance signals. The magnetic resonance imaging device comprises a receiving coil comprising a plurality of receiving coil elements and configured to receive magnetic resonance signals and feed the magnetic resonance signals to a receiver, and a coupler configured to be coupled with at least a first receiving coil element of the receiving coil, the coupler being directionally coupled with at least the receiver, the first receiving coil element being configured to receive a high-frequency electromagnetic wave signal through the coupler. The directional coupling between the coupler and the receiver is so regulated that the first receiving coil element transmits the high-frequency electromagnetic wave signal to the object under test to sense a physiological movement signal.

Abstract: The disclosure relates to a hybrid orthogonal signal generator, a coil transmission front-end device, an RF coil system, and an MRI system. The hybrid orthogonal signal generator has an input end for receiving an RF signal, generates a hybrid orthogonal excitation signal on the basis of the RF signal, and provides the hybrid orthogonal excitation signal by means of an output end of the hybrid orthogonal signal generator, and comprises: a first conductor, arranged in a plane and being arc-shaped; and a second conductor having mutual inductance with the first conductor, the second conductor being connected between the input end and output end, wherein the first conductor and second conductor are parallel and arranged as mirror images of each other. The hybrid orthogonal signal generator has a compact size and is suitable for providing hybrid orthogonal excitation signals for an MRI system with a low field strength.

Abstract: Methods of treating patients suffering from or exhibiting symptoms of mental, behavioral, and/or cognitive disorders with azelastine or a pharmaceutically acceptable salt of azelastine are disclosed.

Abstract: A henhouse includes a gable, a sidewall, and a roof. An inner chamber parallel to the sidewall is provided in the middle of the henhouse. The inner chamber includes an inner wall parallel to the sidewall and an inner roof. A partition is provided between the sidewall and the inner wall. An air inlet plate is provided between the two inner walls located below the inner roof. A pressure chamber is formed between the inner roof and the air inlet plate. A premixing chamber is formed between the inner roof and the roof. A plurality of fans and air inlet windows are uniformly provided on the inner roof. A plurality of air inlet holes and small inlet windows are uniformly provided on the air inlet plate. A plurality of wet curtains and an air vent are provided on the sidewall. A plurality of air outlet slots are uniformly provided on the inner wall.

Abstract: Disclosed is a draw-bar box-type quickly folding micro electric vehicle, comprising of a seat frame assembly (1) that is horizontally arranged, the top surface of which is provided with a foldable backrest. A pair of symmetrically arranged rear wheel assemblies (2) are arranged at a position, close to a rear of the vehicle, on the bottom surface of the seat frame assembly (1), and two vertically downward first connecting posts (101), which are provided near the front of the lower end of the seat frame assembly (1). A footrest assembly (4) is hinged to the lower ends of the two first connecting posts (101) through the first connecting assemblies (3). The footrest assembly (4) is arranged parallel to the seat frame assembly (1), and the plane of the footrest assembly (4) is lower than the plane of the seat frame assembly (1).