Abstract: Machine-readable media, methods, and apparatus are described for transferring data. In some embodiments, an operating system may allocate pages to a buffer and may build a memory descriptor list that references the pages allocated to the buffer. A direct memory access (DMA) controller may process the memory descriptor list and transfer data between a buffer defined by the memory descriptor list and another location per the memory descriptor list. The DMA controller may further support data transfers that involve buffers defined by scatter gather lists and/or chained DMA descriptors built by a device driver.

Abstract: Novel hydroxamic acid compounds are disclosed. These hydroxamates inhibit peptide deformylase (PDF), an enzyme present in prokaryotes and are therefore useful as antimicrobials and antibiotics. Methods of synthesis and of use of the compounds are also disclosed.

Abstract: Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

Abstract: Apparatus and method for carrying out a DMA transfer wherein an address is written into a DMA register of a DMA controller specifying a memory location within a memory device at which either the parameters for a transfer of a block of data are provided or the status of the transfer of a block of data is to be written by the DMA controller.

Abstract: Novel hydroxamic acid compounds are disclosed. These hydroxamates inhibit peptidyl deformylase (PDF), an enzyme present in prokaryotes. The hydroxymates are useful as antimicrobials and antibiotics. The compounds of the invention display selective inhibition of peptidyl deformylase versus other metalloproteinases such as matrix metalloproteinases (MMPs). Methods of synthesis and of use of the compounds are also disclosed.

Abstract: A host system is provided with one or more host-fabric adapters installed therein for connecting to a switched fabric of a data network.

Abstract: Methods of inhibiting various enzymes and treating various conditions are provided that include administering to a subject a compound of Structure I or IB, a pharmaceutically acceptable salt thereof, a tautomer thereof, or a pharmaceutically acceptable salt of the tautomer. Compounds having the Structure I and IB have the following structures and have the variables described herein. Such compounds may be used to prepare medicaments for use in inhibiting various enzymes and for use in treating conditions mediated by such enzymes.

Abstract: Briefly, in accordance with one embodiment of the invention, a system includes: shared memory. The system includes the capability to transfer to a router processing unit a fragment of a received frame and a pointer to the fragment in shared memory. Briefly, in accordance with another embodiment of the invention, a method of transferring a fragment of a received frame includes the following. The received frame and the byte length of a fragment of the received frame are stored in shared memory. The fragment of the received frame having the byte length indicated and a pointer to the location of the fragment in shared memory are transferred. Briefly, in accordance with yet another embodiment of the invention, a switch-router includes at least one integrated circuit.

Abstract: New pyrrole based compounds, compositions and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3 mediated disorders in vivo are provided. The methods, compounds and compositions of the invention may be employed alone, or in combination with other pharmacologically active agents in the treatment of disorders mediated by GSK3 activity, such as diabetes, Alzheimer's disease and other neurodegenerative disorders, obesity, atherosclerotic cardiovascular disease, essential hypertension, polycystic ovary syndrome, syndrome X, ischemia, traumatic brain injury, bipolar disorder, immunodeficiency or cancer.

Abstract: Briefly, in accordance with one embodiment of the invention, a system includes: a network interface unit (NIU) is adapted to monitor bandwidth utilization of the netrwork interface unit and adjust the minimum interval for the transmission of a flow control packet, based, at least in part, on the bandwidth utilization determination.

Abstract: Briefly, in accordance with one embodiment of the invention, a system includes: a network interface unit (NIU). The network interface unit (NIU) is adapted to monitor bandwidth utilization of the network interface unit and adjust the minimum interval for the transmission of a flow control packet, based, at least in part, on the bandwidth utilization determination. Briefly, in accordance with another embodiment of the invention, an apparatus includes at least one integrated circuit. The integrated circuit includes the capability, either alone or in combination with other integrated circuits, to monitor the receive rate utilization of a network interface unit and adjust the minimum interval for the transmission of a flow control frame, based, at least in part, on the receive rate utilization determined.

Abstract: Briefly, in accordance with one embodiment of the invention, an apparatus includes an integrated circuit that has the capability to schedule transferring processes that have an individual identification number. At least a portion of each individual identification number is used to indicate the presence of each of the transfer processes. Briefly, in accordance with another embodiment of the invention, an integrated circuit having a scheduler of transfer processes, each of the transfer processes having an identification number. The scheduler is coupled to a memory array of bits, and a portion of each identification number is used as a portion of an address to the memory array of bits. Briefly, in accordance with yet another embodiment of the invention, a method of scheduling requests for the transfer of data where each request having an identification number. The identification number is used in addressing a bit in an array of bits and set to indicate the request for the transfer of data.

Abstract: Compounds of formula IA and IB are new where the variables R1 through R10 have the values set forth herein. Such compounds have use in treating diseases such as obesity and type II diabetes, and may be provided as pharmaceutical formulations in conjunction with a pharmaceutically acceptable carrier.

Abstract: Briefly, in accordance with one embodiment of the invention, a system includes: shared memory. The system includes the capability to transfer to a router processing unit a fragment of a received frame and a pointer to the fragment in shared memory.

Abstract: Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

Abstract: Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

Abstract: Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

Abstract: Compounds of formula IA and IB are new 1

Abstract: Novel hydroxamic acid compounds are disclosed. These hydroxamates inhibit peptide deformylase (PDF), an enzyme present in prokaryotes and are therefore useful as antimicrobials and antibiotics. Methods of synthesis and of use of the compounds are also disclosed.

Abstract: Novel hydroxamic acid compounds are disclosed. These hydroxamates inhibit peptidyl deformylase (PDF), an enzyme present in prokaryotes. The hydroxymates are useful as antimicrobials and antibiotics. The compounds of the invention display selective inhibition of peptidyl deformylase versus other metalloproteinases such as matrix metalloproteinases (MMPs). Methods of synthesis and of use of the compounds are also disclosed.