Abstract: One aspect of the invention relates to a series of new PCSK9 inhibitor compounds comprising piperidine ring structures, including compounds of formula (I) and/or pharmaceutically acceptable salts thereof. Another aspect of the invention relates to methods of treating PCSK9 receptor related diseases comprising administration of one or more compounds of formula (I) or a pharmaceutically acceptable salt thereof.

Abstract: The embodiments of the present invention provide a touch display panel, a display device and a driving method thereof. The touch display panel comprises an array substrate and a counter substrate; the array substrate comprises a first basal substrate and a spacer, the spacer being arranged on a surface of the first basal substrate facing the counter substrate; the spacer comprises a primary spacer and an auxiliary spacer; each auxiliary spacer at least comprises a conductive portion facing the counter substrate; the height of the auxiliary spacer is less than the height of the primary spacer; the counter substrate comprises a second basal substrate and a touch structure, the touch structure is arranged on a surface of the second basal substrate facing the array substrate.

Abstract: The present invention provides a flux-cored welding wire comprising a shell having a tubular cavity, which accommodates flux. The shell is made of 400 series stainless steels. The deposited metal formed after the welding using the flux-cored welding wire of the present invention has more uniform chemical compositions. Because the loss of chromium during the transition to the deposited metal is less than 0.1%, recourses is saved and welding cost is reduced. The filling ratio of the flux-cored welding wire of the present invention is 5%-25% (preferably 10%-20%). As a result, not only the stability of the compositions in the flux is increased, but also the disadvantages to the manufacture process caused by high filling ratio are avoided. The flux-cored welding wire of the present invention will not be rusty even after it is exposed to the air for a long time.

Abstract: The embodiments of the present invention provide a touch display panel, a display device and a driving method thereof. The touch display panel comprises an array substrate and a counter substrate; the array substrate comprises a first basal substrate and a spacer, the spacer being arranged on a surface of the first basal substrate facing the counter substrate; the spacer comprises a primary spacer and an auxiliary spacer; each auxiliary spacer at least comprises a conductive portion facing the counter substrate; the height of the auxiliary spacer is less than the height of the primary spacer; the counter substrate comprises a second basal substrate and a touch structure, the touch structure is arranged on a surface of the second basal substrate facing the array substrate.

Abstract: A communication converting apparatus for a pulse meter is provided, comprising: a pulse collection unit, configured to collect a pulse signal generated from the pulse meter; a storage unit, configured to store a reading of the pulse meter; a micro control unit, configured to control the pulse collection unit to collect the pulse signal, to read the reading stored in the storage unit, and to obtain an updated reading of the pulse meter according to the pulse signal and the reading stored in the storage unit; and a RS485 communication unit, configured to covert the updated reading of the pulse meter into a RS485 communication signal for outputting.

Abstract: A modified fertilizer structure and a process for making the structure are disclosed. The structure contains at least a first modified oil layer that coats the fertilizer particle. Additional layers may be added as necessary to include a modified fiber layer that coats the modified oil layer, a second and third modified oil layers, a second modified fiber layer, a layer of diatomaceous earth mineral particles and a superabsorbent layer. The structure may be constructed by placing fertilizer particles in a rotating drum, then adding the materials for each layer consecutively into the drum at appropriate conditions. The modified fertilizer structure is configured to gradually release the nutrients into the soil over a desired period of time.

Abstract: The use of the alternating direction method of multipliers (ADMM) algorithm to train a classifier may reduce the amount of classifier training time with little degradation in classifier accuracy. The training involves partitioning the training data for training the classifier into multiple data blocks. The partitions may preserve the joint distribution of input features and an output class of the training data. The training may further include performing an ADMM iteration on the multiple data blocks in an initial order using multiple worker nodes. Subsequently, the training of the classifier is determined to be completed if a stop criterion is satisfied following the ADMM iteration. Otherwise, if the stop criterion is determined to be unsatisfied following the ADMM iteration, one or more additional ADMM iterations may be performed on different orders of the multiple data blocks until the stop criterion is satisfied.

Abstract: Provided is a pulse density modulation value converter, comprising: a pulse density modulation reference point storage for storing a plurality of pulse density modulation reference points, each pulse density modulation reference point comprising a linear pulse density modulation value, an actual pulse density modulation value and/or an integral non-linear error value, wherein the integral non-linear error value is the difference between the actual pulse density modulation value and the linear pulse density modulation value; and a pulse density modulation value calculator for receiving a linear pulse density modulation value, searching the pulse density modulation reference point storage for a pair of pulse density modulation reference points closest to the linear pulse density modulation value, obtaining an actual pulse density modulation value corresponding to the linear pulse density modulation value through linear interpolation on the basis of the pair of pulse density modulation reference points, and outp

Abstract: A system and a method for controlling a ducted air-conditioning system are provided. The system comprises: a temperature controller, configured to generate a first control instruction for controlling the ducted air-conditioning system; a mobile terminal, configured to generate a second control instruction for controlling the ducted air-conditioning system; and a conversion device, connected between the ducted air-conditioning system and the temperature controller, communicating with the mobile terminal via wireless communication, and configured to receive the first control instruction from the temperature controller, and transmit the first control instruction to the ducted air-conditioning system, and to receive the second control instruction from the mobile terminal, convert the second control instruction into a third control instruction, and transmit the third control instruction to the ducted air-conditioning system.

Abstract: A communication converting apparatus for a pulse meter is provided, comprising: a pulse collection unit, configured to collect a pulse signal generated from the pulse meter; a storage unit, configured to store a reading of the pulse meter; a micro control unit, configured to control the pulse collection unit to collect the pulse signal, to read the reading stored in the storage unit, and to obtain an updated reading of the pulse meter according to the pulse signal and the reading stored in the storage unit; and a RS485 communication unit, configured to covert the updated reading of the pulse meter into a RS485 communication signal for outputting.

Abstract: The present disclosure provides a full duplex communication method implemented by a Radio Base Station (RBS) supporting Time Division Duplex (TDD) scheme and the associated RBS. The method comprises configuring a first logic cell and a second logic cell for the RBS by specifying a first downlink/uplink (DL/UL) configuration corresponding to the first logic cell and a second, different DL/UL configuration corresponding to the second logic cell.

Abstract: A method for forming a molded fiber bottle by pressurizing a flexible plastic bag in a molded pulp bottle preform to press the bag against the inner wall of the molded pulp bottle preform and thereby assist dewatering of the preform and form an internal plastic liner in the molded pulp bottle preform such that the liner provides a barrier function for the bottle and the resulting bottle produced by the method.

Abstract: An electronic device housing includes a plastic substrate. The plastic substrate includes a first surface. The electronic device housing further includes an activating layer formed on the first surface. The activating layer contains metal powder. The activating layer defines a recessed portion. Some of the metal powder is partially exposed on the surface of the recessed portion. Some of metal powder is partially inserted into the plastic substrate corresponding to the recessed portion. The electronic device housing further includes an antenna layer formed on the recessed portion. The antenna layer is a metal layer. A method for manufacturing the electronic device housing is also disclosed.

Abstract: Methods and systems for i-vector based clustering training data in speech recognition are described. An i-vector may be extracted from a speech segment of a speech training data to represent acoustic information. The extracted i-vectors from the speech training data may be clustered into multiple clusters using a hierarchical divisive clustering algorithm. Using a cluster of the multiple clusters, an acoustic model may be trained. This trained acoustic model may be used in speech recognition.

Abstract: An implantable device includes a stimulation electronic circuit, a battery, a receiver configured to receive energy from a source external to the implantable stimulation device, and a battery charger circuit configured to use the energy to charge the battery and power the stimulation electronic circuit, the battery charger circuit including a load switch for connecting/disconnecting the battery, the load switch being controlled by the stimulation electronic circuit.

Abstract: An exemplary sound processor apparatus included in an auditory prosthesis system includes a linear regulator and a sound processing integrated circuit (“IC”). The linear regulator 1) receives a source voltage signal having a source voltage level and provided by an external power source, 2) drops the source voltage level to an intermediate voltage level, and 3) outputs an intermediate voltage signal having the intermediate voltage level. The sound processing IC 1) performs one or more sound processing operations with respect to an audio signal presented to a patient associated with the auditory prosthesis system, 2) receives the intermediate voltage signal having the intermediate voltage level, 3) converts the intermediate voltage level into one or more supply voltage levels, and 4) outputs one or more supply voltage signals having the one or more supply voltage levels.

Abstract: An implantable device includes a stimulation electronic circuit, a battery, a receiver configured to receive energy from a source external to the implantable stimulation device, and a battery charger circuit configured to use the energy to charge the battery and power the stimulation electronic circuit, the battery charger circuit including a load switch for connecting/disconnecting the battery, the load switch being controlled by the stimulation electronic circuit.

Abstract: An automatic fire-extinguishing and fire-fighting device for an electric automobile, comprising a powder bottle (2), a bottle head valve (4) connected to the lower part of the powder bottle (2), and a gas bottle (5) connected to the lower part of the bottle head valve (4); the powder bottle (2) is connected to the bottle head valve (4) via a truncated-cone-shaped connecting piece (7); a central gas outlet (9) is disposed along an axis; three lateral gas outlets (10) are uniformly distributed on a side surface; an angle of 100 degrees is formed between the lateral gas outlets (10) and the central axis of the powder bottle (2). The automatic fire-extinguishing and fire-fighting device for an electric automobile separates the powder bottle from the gas bottle, improving device safety and stability; the connection structure enables the gas and powder to be fully mixed, thus achieving better fire-extinguishing and fire-fighting effect.