Abstract: Provided is a content evaluation system including an electronic pen, a data generation section that generates content data from writing operations performed by the electronic pen, a data acquisition section that acquires the content data, a first calculation section that calculates, from the acquired content data, a plurality of kinds of time-series feature amounts indicating a temporal change in a plurality of kinds of feature amounts related to a creation process of the handwritten content, a second calculation section that calculates an integrated feature amount related to the creation process of the handwritten content by using two or more kinds of time-series feature amounts from among the plurality of kinds of time-series feature amounts, and a content evaluation section that evaluates the handwritten content in reference to the integrated feature amount and outputs evaluation result information indicating the evaluation result of the handwritten content.

Abstract: A power amplifier (PA) linearization technique with a wider linearized power range is proposed. Proposed two types of linearizers with cross-coupled PMOS and NMOS configuration. The idea is to use a complimentary device compared with the PA core device, and the behavior of Cgs of the linearizer are also complimentary to the PA itself. In the other words, the overall Cgs of the PA with the linearizer would be constant without leading to non-linear waveform. Both linearizers can effectively compensate not only AMAM but also AMPM. First type of linearizer can be integrated with PA cores, and second type of linearizer can be used in the IMN. Both linearizers have effective IM3 reduction in different corner.

Abstract: Provided is a content evaluation device including a processor and a memory storing a program that, when executed by the processor, causes the content evaluation device to: calculate a state feature relating to a drawing state in a creation period from a start timing to an end timing of creation of content, and generate a picture-print that is a set or locus of points on a feature space that represents the state feature.

Abstract: An ultrasound scanning control method applied to an ultrasound scanning device is provided. The ultrasound scanning device includes an execution mechanism. The execution mechanism includes a mechanical arm and a probe. The ultrasound scanning control method includes controlling the mechanical arm to drive the probe to move according to a set scanning trajectory for performing an ultrasound scanning detection on a part to be examined. Once an actual pressure value between the probe and the part to be examined in each control cycle is sensed using the force sensor, a pressure value between the probe and the part to be examined is controlled to be a constant value based on the actual pressure value.

Abstract: A content evaluation device includes a feature calculating section that calculates a state feature amount relating to a drawing state in a creation period from a start timing to an end timing of creation of content, and a display instructing section. The display instructing section instructs displaying of picture-print information indicating a picture-print, which is a set or a trace of points in a feature space for representing the state feature amount calculated by the feature calculating section, or displaying of derived information derived from the picture-print.

Abstract: Provided is a content evaluation device including a processor and a memory storing a program that, when executed by the processor, causes the content evaluation device to: acquire at least one of content data indicating content composed of multiple content elements or related data relating to creation of the content, calculate a time-series feature indicating a time change of a feature relating to a creation process of the content from the content data or the related data, and evaluate the content by using the time-series feature.

Abstract: The present disclosure provides an isolated recombinant oncolytic adenovirus, a pharmaceutical composition, and uses thereof for drugs for treatment of tumors and/or cancers. The recombinant oncolytic adenovirus is a selectively replicating oncolytic adenovirus, and the genome of the recombinant oncolytic adenovirus is integrated with a coding sequence of exogenous shRNA capable of inhibiting PDL1 expression in tumor cells. The replication capability of the virus in normal primary cells is much lower than the replication capability of the virus in tumor cells. Moreover, the expressed shPDL1 can significantly reduce the level of PDL1 protein highly expressed in tumor cells. Thus, the oncolytic killing effect of the oncolytic virus and the anti-tumor immunostimulatory effect of immune cells produce a synergistic effect.

Abstract: An ultrasound scanning control method applied to an ultrasound scanning device is provided. The ultrasound scanning device includes an execution mechanism. The execution mechanism includes a mechanical arm and a probe. The ultrasound scanning control method includes controlling the mechanical arm to drive the probe to move according to a set scanning trajectory for performing an ultrasound scanning detection on a part to be examined. Once an actual pressure value between the probe and the part to be examined in each control cycle is sensed using the force sensor, a pressure value between the probe and the part to be examined is controlled to be a constant value based on the actual pressure value.

Abstract: An ultrasound scanning control method applied to an ultrasound scanning device is provided. The ultrasound scanning device includes an execution mechanism. The execution mechanism includes a mechanical arm and a probe. The ultrasound scanning control method includes: controlling the mechanical arm to drive the probe to move according to a set scanning trajectory; and controlling the probe to collect an ultrasound image. A target region is identified from the collected ultrasound image. The scanning trajectory is adjusted when a position of the target region in the ultrasound image is not a predetermined position, and the mechanical arm is controlled to drive the probe to move according to the adjusted scanning trajectory.

Abstract: The present disclosure provides an isolated recombinant oncolytic adenovirus, a pharmaceutical composition, and uses thereof for drugs for treatment of tumors and/or cancers. The recombinant oncolytic adenovirus is a selectively replicating oncolytic adenovirus, and the genome of the recombinant oncolytic adenovirus is integrated with a coding sequence of exogenous shRNA capable of inhibiting PDL1 expression in tumor cells. The replication capability of the virus in normal primary cells is much lower than the replication capability of the virus in tumor cells. Moreover, the expressed shPDL1 can significantly reduce the level of PDL1 protein highly expressed in tumor cells. Thus, the oncolytic killing effect of the oncolytic virus and the anti-tumor immunostimulatory effect of immune cells produce a synergistic effect.

Abstract: Provided are therapeutic agent including nucleic acid and CAR-modified immune cell and the use thereof. The therapeutic agent comprises first composition and second composition, the first composition comprises a nucleic acid having a labeling polypeptide coding sequence for being introduced into a tumor cell and/or a cancer cell; the labeling polypeptide has an extracellular antigen determining region, a spacer portion, and a transmembrane portion that are operatively linked, which can be expressed to form modification on the surface of the tumor cell and/or cancer cell; the extracellular antigen determining region comprises one or more epitope polypeptides; wherein, amino acid sequences of proteins on cell membrane or secreted proteins of mammal do not comprise the epitope polypeptide amino acid sequence in the natural state; the second composition comprises chimeric antigen receptor modified immune cell which specifically recognize and bind to the extracellular antigen determining region.

Abstract: Provided are an isolated recombinant oncolytic poxvirus capable of being regulated and controlled by microRNA and a use thereof. The isolated recombinant oncolytic poxvirus can be regulated and controlled by microRNA, and the expression level of the microRNA in tumor cells of a mammal is lower than that in normal cells of the same mammal. A target sequence of the microRNA is integrated in a 3?UTR region of an E10R gene in a recombinant oncolytic poxvirus genome.

Abstract: A pliers includes a first body with an engaging groove and a second body with an elongated slot pivotally connected with each other. The elongated slot includes a left and right positioning grooves and a protruding portion disposed therebetween. A tap button is pivotally connected to the second body. A supporting member is disposed between the second body and the tap button. When the first body comes close to the second body, the tap button can be tapped to a first position and engaged in the engaging groove. Thus, the first body is blocked and cannot pivot relative to the second body. The tap button can be tapped to a second position and detached from the engaging groove. Thus, the first body is pivotable relative to the second body. A positioning block is extending from the tap button and can be engaged in any of the positioning grooves for positioning the tap button.

Abstract: An electronic device including a holder, a first buffer element, a second buffer element and a loudspeaker is provided. The holder includes a first section and a second section perpendicular to the first section. The first section and the second section are respectively provided with a first opening and a second opening. The first buffer element is disposed in the first opening of the first section. The second buffer element is disposed in the second opening of the second section. The loudspeaker is supported on the housing by the holder. The first buffer element is connected to the loudspeaker, and the second buffer element is connected to the housing.

Abstract: A method for processing image data and a system thereof are provided. The method is operated in the system including an encoding system and a decoding system. In the decoding system, multiple image data packages are received from the encoding system. The image data packages include multiple encoded data that are formed by encoding the pixels of an image and the pixels are beforehand rearranged according to an arrangement order. The arrangement order is exemplarily made based on the quantity of encoding circuits of the encoding system. In the decoding system, the encoded data received from the encoding system are sequentially stored in a memory according to the arrangement order. The decoding circuits start to decode the encoded data from an initial code synchronously for enhancing decoding performance. The method can be applied to decoding of high resolution images. The image is reproduced after the decoding process.

Abstract: A digital circuit robustness verification method is provided that includes the following steps. An internal storage circuit and an external storage circuit corresponding to a circuit under test are set to store a plurality of random values and a configuration of the circuit under test for performing a predetermined function is set by a processing circuit. A driving signal corresponding to the predetermined function is transmitted to the circuit under test by a previous stage circuit, such that the circuit under test executes the predetermined function to further generate an output signal. The determination as to whether the output signal is correct or not is made by a next stage circuit, and the circuit under test is determined to pass a robustness verification when the output signal is correct.

Abstract: A pliers has guiding surfaces at tooth portions of the first pliers body and tooth portions of the engaging unit of the control member. Therefore, when the pressing block of the control member is not pressed, even if the first pliers body is engaged with the tooth portions of the engaging unit, the second pliers body can still be pushed forward relative to the first pliers body, so that the second guiding surfaces of the second tooth portions of the engaging unit slide relative to the first guiding surfaces of the first tooth portions and each of the first tooth portions is moved to engage with a next corresponding second tooth portion, thereby allowing the second pliers portion being movable toward the first pliers portion. Hence, the clamping distance of the pliers can be adjusted to match with an object to be clamped.

Abstract: An ultrasound scanning control method applied to an ultrasound scanning device is provided. The ultrasound scanning device includes an execution mechanism. The execution mechanism includes a mechanical arm and a probe. The ultrasound scanning control method includes: controlling the mechanical arm to drive the probe to move according to a set scanning trajectory; and controlling the probe to collect an ultrasound image. A target region is identified from the collected ultrasound image. The scanning trajectory is adjusted when a position of the target region in the ultrasound image is not a predetermined position, and the mechanical arm is controlled to drive the probe to move according to the adjusted scanning trajectory.

Abstract: A power amplifier (PA) linearization technique with a wider linearized power range is proposed. Proposed two types of linearizers with cross-coupled PMOS and NMOS configuration. The idea is to use a complimentary device compared with the PA core device, and the behavior of Cgs of the linearizer are also complimentary to the PA itself. In the other words, the overall Cgs of the PA with the linearizer would be constant without leading to non-linear waveform. Both linearizers can effectively compensate not only AMAM but also AMPM. First type of linearizer can be integrated with PA cores, and second type of linearizer can be used in the IMN. Both linearizers have effective IM3 reduction in different corner.

Abstract: A pliers includes a first body with an engaging groove and a second body with an elongated slot pivotally connected with each other. The elongated slot includes a left and right positioning grooves and a protruding portion disposed therebetween. A tap button is pivotally connected to the second body. A supporting member is disposed between the second body and the tap button. When the first body comes close to the second body, the tap button can be tapped to a first position and engaged in the engaging groove. Thus, the first body is blocked and cannot pivot relative to the second body. The tap button can be tapped to a second position and detached from the engaging groove. Thus, the first body is pivotable relative to the second body. A positioning block is extending from the tap button and can be engaged in any of the positioning grooves for positioning the tap button.