Abstract: Disclosed is a continuous ingot growing apparatus. The continuous ingot growing apparatus according to the present invention may include a growth furnace in which a main crucible is positioned, wherein the main crucible accommodates molten-state silicon to grow an ingot, a material supply unit which supplies a solid-state silicon material before being melted into molten-state silicon, a quantitative supply unit which measures an amount of the solid-state silicon material supplied from the material supply unit and supplies a predetermined amount of the solid-state silicon material, and a preliminary melting unit which melts the predetermined amount of the solid-state silicon material supplied from the quantitative supply unit and supplies molten-state silicon to the main crucible.

Abstract: The present invention relates to a continuous ingot growing apparatus, and more specifically, to a continuous ingot growing apparatus which melts a solid silicon material supplied to a preliminary crucible to supply the solid silicon material to a main crucible and which can adjust a supply amount of molten silicon while blocking floating matter floating on top of the molten silicon so as not to be supplied.

Abstract: Disclosed is an ingot growing apparatus. The ingot growing apparatus according to the embodiment of the present invention includes a growth furnace in which a main crucible is disposed, wherein the main crucible accommodates molten silicon to grow an ingot, a preliminary crucible which receives a solid silicon material, melts the solid silicon material, and supplies molten silicon to the main crucible, a measurement unit which is installed to pass through the growth furnace and measures a change in level of the surface of the molten silicon in the main crucible, and a control unit which controls supply of the molten silicon in the preliminary crucible to the main crucible on the basis of the measured change in the level of the surface of the molten silicon.

Abstract: The present invention relates to mouse antibodies that bind to angiopoietin-2 (Ang2), humanized anti-Ang2 antibodies derived therefrom, and the use thereof. The anti-Ang2 antibodies have a dual function of activating the Tie2 receptor together with neutralizing Ang2. The anti-Ang2 antibodies show the property of normalizing abnormal and pathological blood vessels, and thus exhibits therapeutic efficacy against various diseases and disorders associated with abnormal blood vessels. The present invention further provides an angiogenesis inhibitor and a composition for treatment of diseases associated with abnormal Ang2 expression and Tie2 dysregulation, which comprise the antibody as an active ingredient, and a composition for diagnosing diseases associated with Ang2 inhibition and Tie2 activation, which comprises the antibody.

Abstract: The present invention provides an ultra high strength cold rolled steel sheet having excellent spot weldability and formability. The ultra high strength cold rolled steel sheet, according to one embodiment of the present invention, comprises, in weight percent,: 0.05% to 0.09% of carbon (C); 0.5% to 1.0% of silicon (Si); 2.0% to 2.8% of manganese (Mn); 0.2% to 0.5% of aluminum (Al); 0.8% to 1.2% of chromium (Cr); 0.05% to 0.10% of molybdenum (Mo); 0.03% to 0.06% of titanium (Ti); 0.001% to 0.003% of boron (B); 0.02% to 0.05% of antimony (Sb); 0.001% to 0.015% of phosphorus (P); more than 0% to 0.003% of sulfur (5); 0.004% to 0.006% of nitrogen (N); and a balance of iron (Fe) and other inevitable impurities, and the ultra high strength cold rolled steel sheet comprises a microstructure comprising ferrite and low hardness martensite.

Abstract: A method for determining the status of a robot according to an embodiment includes acquiring first data and second data related to an operation of the robot, acquiring a resonance frequency by analyzing the operation of the robot in a frequency region based on the first data related to the operation of the robot, acquiring a first comparison result by comparing the acquired resonance frequency with a reference resonance frequency, when the first comparison result is a threshold value or more, generating a Lissajous figure by DQ transforming a three-phase signal based on the second data related to the operation of the robot, acquiring a second comparison result by comparing the generated Lissajous figure with a reference Lissajous figure, and determining the status of the robot based on at least one of the first comparison result and the second comparison result.

Abstract: Provided is a method of inspecting a growth quality of a graphene layer of a graphene-grown copper foil obtained by growing the graphene layer on a copper foil layer by chemical vapor deposition (CVD), the method including reacting oxygen or water molecules with the copper foil layer via a defect portion of the graphene layer, partitioning an entire region of the graphene-grown copper foil into partial regions, sequentially obtaining images of the partial regions, detecting, with respect to each of the images of the partial regions, an oxidized region where the copper foil layer is oxidized, and setting the oxidized region as a graphene defect region, and obtaining a ratio of an area of the graphene defect region to an entire area of each of the images of the partial regions.

Abstract: The present disclosure relates to a facility guide robot that provides necessary information to a user who uses the facility while moving inside the facility. Specifically, the present disclosure relates to a facility guide robot and a facility guide method using the same, wherein the facility guide robot may actively provide the guide information to the facility users before the facility user requests to use the facility guide robot. That is, the convenience of the facility user may be improved by allowing the facility guide robot to provide the guide information necessary to the facility user before the facility user, who needs the guide, checks or calls the facility guide robot to receive the guide information.

Abstract: The present invention relates to mouse antibodies that bind to angiopoietin-2 (Ang2), humanized anti-Ang2 antibodies derived therefrom, and the use thereof. The anti-Ang2 antibodies have a dual function of activating the Tie2 receptor together with neutralizing Ang2. The anti-Ang2 antibodies show the property of normalizing abnormal and pathological blood vessels, and thus exhibits therapeutic efficacy against various diseases and disorders associated with abnormal blood vessels. The present invention further provides an angiogenesis inhibitor and a composition for treatment of diseases associated with abnormal Ang2 expression and Tie2 dysregulation, which comprise the antibody as an active ingredient, and a composition for diagnosing diseases associated with Ang2 inhibition and Tie2 activation, which comprises the antibody.

Abstract: The present invention relates to a working robot. According to one embodiment of the present invention, the working robot comprises: a body; a plurality of traveling units connected to the body, having supporting members and traveling members rotatably connected to the supporting members, and provided so as to be travelable with respect to the ground; and a plurality of adjusting units connecting the body and the traveling units, and provided to enable the relative positions of the traveling units to the body to be adjusted, wherein the plurality of traveling units are traveled and the plurality of adjusting units are adjusted so as to maintain the horizontal state of the body.

Abstract: An esterification reaction apparatus and an esterification reaction method, the esterification reaction apparatus comprising a reaction tank having an accommodation part, in which a raw material containing carboxylic acid and alcohol is accommodated, a heating unit configured to individually heat partition regions that are partitioned into N regions in a vertical direction of the accommodation part, and a controller configured to control the heating unit so that only the partition regions in which a liquid is accommodated among the N partition regions are heated, thereby performing an esterification reaction of the raw material.

Abstract: Provided is an aluminum ion detector. The aluminum ion detector may include apple extracts having a predetermined concentration, and metal nano particles coupled to the apple extracts.

Abstract: The present invention provides a bispecific epitope binding protein comprising an anti-4-1BB agonist antibody and a PD-1 protein or a fragment thereof that binds to PD-L1 with high affinity. The bispecific epitope binding protein simultaneously and independently binds to 4-1BB and PD-L1, which engage 4-1BB upregulated T cells, especially effector CD8+ T cells, with tumor cells expressing PD-L1. These interactions induce strong activation of the cytotoxic activity of anti-tumor effector CD8+ T cells by both blocking PD-1/PD-L1-mediated inhibitory signaling and activating 4-1BB-mediated costimulatory signaling in mouse models. This bispecific epitope binding protein has a much stronger oncolytic effect compared to each component alone.

Abstract: The present disclosure relates to a diester-based material production unit including a reaction device in which an esterification reaction of dicarboxylic acid and a primary alcohol is performed, a column in which the gas-liquid separation of the primary alcohol and the water introduced is performed, a heat exchanger installed on a gas phase line of the column to remove heat of the gas phase line, a flash drum in which separation of a liquid phase and a gas phase is performed in the mixture stream including the primary alcohol and the water, a condenser installed on the flash drum upper line, and a layer separator in which the layer separation of a mixture of a liquefied primary alcohol and water into an organic layer and an aqueous layer is performed, wherein one or more lines through which recirculated primary alcohol from the flash drum and the layer separator flows are connected to an upper portion of the column.

Abstract: A neutralization/water separation tank for an esterified product including: a neutralization part in which a crude product mixture containing alcohol and an ester compound, a neutralizing agent, and water are put to produce a neutralized mixture; a water separation part which divides the neutralized mixture into a floating layer and an aqueous layer; a first partition wall which extends upward from a bottom surface to provide an upper passage and by which the neutralization part and the water separation part are partitioned; and a second partition wall which extends downward from a ceiling to provide a lower passage, wherein the water separation part includes: a first water separation part into which the neutralized mixture is introduced from the neutralization part through the upper passage; and a second water separation part into which the neutralized mixture is introduced from the first water separation part through the lower passage, wherein the first water separation part and the second water separation

Abstract: A neutralization/water separation device for an esterified product including: a neutralization tank in which a crude product mixture containing alcohol and an ester compound, a neutralizing agent, and water are put to produce a neutralized mixture; a water separation tank disposed below the neutralization tank to divide the neutralization mixture into a floating layer and an aqueous layer; a partition wall extending downward from a ceiling of the water separation tank to provide a lower passage in the water separation tank; and a transfer line that transfers the neutralized mixture from the neutralization tank to the water separation tank, where the water separation tank includes: a first water separation part into which the neutralized mixture is introduced from the neutralization tank through the transfer line; and a second water separation part into which the neutralized mixture is introduced from the first water separation part through the lower passage, where the first water separation part and the secon

Abstract: Provided is a heavy metal detecting sensor. The heavy metal detecting sensor includes an electrode and a plurality of amyloid fibers disposed on the electrode, wherein an amount of a redox current of the electrode decreases when the plurality of amyloid fibers react with heavy metal ions.

Abstract: Provided are PD-1 polypeptide variants including an extracellular domain that binds specifically to PD-L1, and a transmembrane domain or a fragment thereof. The disclosure also provides PD-1 Fc fusion proteins including an immunoglobulin Fc region, and a PD-1 polypeptide variant.

Abstract: Disclosed are a method and an apparatus for recommending clothing coordination information in the 5G communication environment by executing an artificial intelligence (AI) algorithm and/or a machine learning algorithm, which have been mounted therein.

Abstract: A bispecific epitope binding protein having a multimer of four single-chain chimeric polypeptides of two single-chain chimeric heavy chains and two single-chain chimeric light chains. The bispecific epitope binding protein has a first antigen binding domain that binds specifically to HER2 and a second antigen binding domain that binds specifically to 4-1BB.