Abstract: The present disclosure provides an N protein epitope mutation marker for preparing an epitope deletion-marked vaccine strain of type II porcine reproductive and respiratory syndrome virus (PRRSV) and use thereof, belonging to the technical field of biological products. In the mutation marker, one or more amino acids are mutated based on an epitope sequence at positions 92 to 103 of a C-terminal of an N protein of the type II PRRSV; and the epitope mutation marker has an amino acid sequence shown in SEQ ID NO: 1, where X1 is selected from the group consisting of T, P, and A; and X2 is selected from the group consisting of V and A.

Abstract: A relative positioning authorization method, a relative positioning authorization device, a terminal and a target device are provided. The relative positioning authorization method includes: transmitting, by a first terminal, a first relative positioning request message to a target device; and receiving, by the first terminal, a first relative positioning response message transmitted by the target device, and determining, by the first terminal, that relative positioning authorization has been completed. The target device is a network side device or at least one second terminal.

Abstract: Provided are an RNA plasmid delivery system and an application thereof. The RNA plasmid delivery system comprises a plasmid carrying an RNA fragment required to be delivered; the plasmid can be enriched in an organ tissue of a host, and spontaneously forms an exosome containing the RNA fragment in the organ tissue of the host, and therefore can enter and be combined with a target tissue to deliver the RNA fragment into the target tissue. The RNA delivery system is safe, reliable, good in druggability, and strong in universality.

Abstract: Provided are a gene circuit, an RNA delivery system and the use thereof. Specifically, the gene circuit comprises at least an RNA fragment capable of inhibiting gene expression and/or a targeting tag having a targeting function. The gene circuit can be delivered to a host, enriched in organ tissues of the host and self-assembled to form a complex structure, and inhibits gene expression by means of the RNA fragment, thereby treating diseases. The delivery system comprises the gene circuit and a delivery carrier capable of delivering the gene circuit to organ tissues of a host for enrichment. The provided gene circuit has a targeting function and a treatment function, can quickly and accurately reach target organs and target tissues to exert a treatment effect, and is highly efficient with good results. The safety and reliability of the provided RNA delivery system are fully verified, and the RNA delivery system has good druggability, high universality, and great economic benefits and application prospects.

Abstract: An RNA delivery system for the treatment of Huntington's disease. The system comprises a viral vector, the viral vector carries RNA fragments capable of treating Huntington's disease, the viral vector is capable of enrichment in organ tissues of a host and endogenously and spontaneously forming a complex containing the RNA fragments capable of treating Huntington's disease in the organ tissues of the host, and the complex can deliver the RNA fragments into a target tissue to treat Huntington's disease. The safety and reliability of the RNA delivery system for the treatment of Huntington's disease have been fully verified. The system has good medicinal properties, strong versatility, and has economic benefits and application prospects.

Abstract: Provided are a viral vector-based RNA delivery system and a use thereof. The RNA delivery system comprises a viral vector. The viral vector carries an RNA fragment needing to be delivered, and can be enriched in organ tissues of a host. In the host organ tissues, the viral vector can endogenously and spontaneously form a composite structure containing the RNA fragment. The composite structure can enter and bind to target tissues, and feed the RNA fragment into the target tissues. The viral vector has a targeting tag. The composite structure is an exosome. The viral vector RNA delivery system is safe and reliable, and has good druggability and high universality.

Abstract: The present disclosure discloses a method for quantifying a bearing capacity of foundation containing shallow-hidden spherical cavities, comprising: in Step 1, constructing a spatial axisymmetric calculation model for stability analysis of the foundation containing shallow-hidden spherical cavities; in Step 2, solving the model to obtain a general solution which reflects the spatial stress distribution of surrounding rock containing shallow-hidden spherical cavities; in Step 3, obtain a mathematical expression by derivation for calculating the bearing capacity of the foundation containing shallow-hidden spherical cavities; and in Step 4: completing the determination of the foundation bearing capacity. Benefits: This method has many advantages such as comprehensive consideration, high accuracy and reliability of calculation results, and may provide the scientific basis for the development of prevention and control against the instability of the foundation containing shallow-hidden cavities.

Abstract: Provided in the present application are a positioning method and apparatus, and a terminal and a storage medium. On a first terminal side, the positioning method includes: acquiring positioning service information of a target terminal; determining from the target terminal, according to the positioning service information, a primary positioning terminal for providing a primary positioning service and a secondary positioning terminal for providing a secondary positioning service; and performing positioning for a location of a first terminal based on the primary positioning terminal and the secondary positioning terminal. Since the positioning of the first terminal can be assisted by the primary positioning terminal and the secondary positioning terminal, the location of the first terminal can be accurately positioned even if a network coverage area where the first terminal is located does not have a proper positioning server therein to provide a positioning service.

Abstract: A method and system for providing access to a resource. A request for an individual within an organization to access the resource is received. In response to the request having been received, at least one constraint for accessing the resource by the individual is ascertained, based on respective constraints for accessing the resource by one or more other individuals in the organization. The one or more other individuals have a same role in the organization as the individual or have a respective relationship with the individual. The at least one constraint is provided to the individual.

Abstract: The present invention provides a keratin BD-3, a nucleic acid molecule encoding same, an expression vector, a host cell, a preparation method therefor, and a pharmaceutical composition contained the keratin BD-3. The keratin BD-3 can be used in the preparation of medicament for antipyretic, analgesic, antitussive, expectorant, anticonvulsant, antiepileptic, anti-hypertension, anti-inflammatory, and antiviral.

Abstract: A system including one or more processors and one or more non-transitory computer-readable media storing computing instructions that, when executed on the one or more processors, perform certain acts. The acts can include obtaining an original load design for loading a trailer to deliver stacks of pallets to physical stores. The load design specifies a respective floor spot assignment for each of the stacks. The original load design satisfies center-of-gravity constraints. The acts also can include generating fluid groups of the stacks to form an initial fluid grouping. The acts additionally can include determining that the fluid groups do not collectively satisfy the center-of-gravity constraints. The acts further can include until the fluid groups collectively satisfy the center-of-gravity constraints, repeatedly determining one or more infeasible groups from the fluid groups, and adjusting at least one of the one or more infeasible groups to update the fluid groups.

Abstract: Techniques are described with respect to a system, method, and computer product for visualizing viewpoints. An associated method includes receiving access to a multi-party discussion occurring via a telecommunication system and analyzing the multi-party discussion using natural language processing. The method further includes extracting a plurality of viewpoints of the multi-party discussion based on the analysis, synthesizing a subset of the plurality of viewpoints based on the content of each viewpoint of the plurality of viewpoints, and transmitting a rendered synthesized visualization of the subset.

Abstract: The present disclosure provides a gene combination for expressing and producing terrequinone A in Escherichia coli and use thereof. The gene combination includes a tdiAS gene, a tdiBS gene, a tdiCS gene, a tdiDS gene, a tdiES gene, an sfpS gene, an ScCKS gene, and an AtIPKS gene with nucleotide sequences set forth in SEQ ID NOS:1 to 8. In the present disclosure, a recombinant engineered strain capable of producing terrequinone A having anti-cancer activity is obtained by separately constructing recombinant plasmids pC02 and pU03 through the eight genes and transforming the two recombinant plasmids into E. coli. The content of terrequinone A in a fermentation broth thereof is 106.3 mg/L, which has potential application value in the biopharmaceutical field.

Abstract: A method including obtaining information about a trailer that has been partially loaded with preloaded stacks in a manner that deviates from an original load design. The trailer is loaded with stacks of pallets including (i) the preloaded stacks that have already been loaded in the trailer and (ii) unloaded stacks that have not yet been loaded into the trailer. The method also can include determining positions of empty floor spots remaining in the trailer. The method additionally can include determining a first portion of an incremental load design for the unloaded stacks using a gap-filling pattern behind an uneven rear edge of the preloaded stacks in the trailer. The method further can include determining a second portion of the incremental load design.

Abstract: The present invention discloses a fabrication method and use of a ?40 mm large-size and high-contrast fiber optic image inverter, belonging to the field of manufacturing of fiber optic imaging elements. The light-absorbing glass for preparing the ?40 mm large-size and high-contrast fiber optic image inverter consists of the following components in molar percentage: SiO2 60-69.9, Al2O3 1.0-10.0, B2O3 10.1-15.0, Na2O 1.0-8.0, K2O 3.0-10.0, MgO 0.1-1.0, CaO 0.5-5.0, ZnO 0-0.1, TiO2 0-0.1, ZrO2 0.1-1.0, Fe2O3 3.0-6.5, Co2O3 0.1-0.5, V2O5 0.51-1.5 and MoO3 0.1-1.0. The fiber optic image inverter has the advantages of low crosstalk of stray light, high resolution and high contrast.

Abstract: The present application relates to the technical field of wireless communications, and discloses a terminal location capability reporting method and device. The method comprises: an access and mobility management function (AMF) entity obtains and stores a terminal location capability of a terminal, and after a location service for a target terminal arrives, if the terminal location capability of the target terminal is stored in the AMF entity, the AMF entity transmits the terminal location capability of the target terminal to a location management function (LMF) entity, so that the LMF sets a location method for the target terminal according to the terminal location capability. In the process above, when the LMF entity needs to obtain the terminal location capability of the target terminal, the terminal location capability of the target terminal can be directly obtained from the AMF entity, and there is no need to interact with the terminal to obtain the terminal location capability.

Abstract: Provided are a response receiving and sending method, a retransmission method, a communication device, and a storage medium. The method includes: sending a transport block to a first communication device through a pre-configured period resource, and receiving a correct response corresponding to the transport block on a pre-configured correct response resource.

Abstract: A data transmission processing method, a data transmission processing apparatus and a processor-readable storage medium are provided. The method includes: sending small data packets to a network node when the UE is in a Radio Resource Control RRC inactive state; performing a RRC-related process and/or a Non-Access Stratum NAS-related process during sending the small data packets to the network node.

Abstract: A positioning method is performed by a first user equipment (UE). The method includes: acquiring a positioning request sent by a communication device, wherein the positioning request is configured to indicate the first UE to send positioning information at a sidelink interface; and sending the positioning information at the sidelink interface.

Abstract: The present application provides a method and an apparatus for controlling data transmission, and a storage medium. The method includes: receiving, by a terminal, configuration information of SDT from a network device; when a terminal is in an idle state or an inactive state, if the terminal determines that first data is to be sent, and that the configuration information of the SDT does not meet a transmission requirement of the first data, sending first information to the network device, where the first information is used to indicate that there exists the first data to be sent at the terminal, and to inform the network device that there exists the first data to be sent at the terminal whose transmission requirement does not match the configuration information of the SDT.