Abstract: A method for preparing a copper-based graphene/aluminum composite wire with high electrical conductivity is disclosed. An electrodeposition solution for the wire includes the following components, in mass percentage: 20 wt % of CuSO4, 0.005 wt % to 0.020 wt % of benzalacetone, 2 wt % to 5 wt % of NaCl, 0.08 wt % to 0.5 wt % of graphene, 0.003 wt % to 0.016 wt % of N,N-dimethylformamide (DMF), and the balance of deionized water. The preparation process of the wire is composed of: electrodeposition, drawing, and annealing. The obtained wire has excellent electrical conductivity and tensile strength, which can effectively improve the electric power transmission efficiency and reduce the electrical power loss. By the above electrodeposition solution and simple preparation method, a utility model wire with high transmission efficiency can be prepared, where the comprehensive performance and microstructure of the composite can be ensured by controlling process parameters.

Abstract: A pixel driving circuit includes a reset sub-circuit, an input sub-circuit, a driving sub-circuit, a compensation sub-circuit and an voltage control sub-circuit. The reset sub-circuit is configured to be turned on in response to a control signal, and transmit a reference voltage to a first node to reset a voltage of the first node. The input sub-circuit is configured to transmit a data signal to a second node in response to a gate scan signal. The driving sub-circuit is configured to be turned on or off in response to a voltage of the first node; and to write the data signal and a compensation signal into a third node. The compensation sub-circuit is configured to transmit the data signal and the compensation signal to a fourth node in response to the gate scan signal. The voltage control sub-circuit is configured to control the voltage of the first node according to a voltage of the fourth node.

Abstract: This application provides a traffic classification method and apparatus. The method includes: determining, based on distribution characteristics of concerned bits of a plurality of rules in a first rule set, an effective bit corresponding to the first rule set; determining a hash key value of each rule based on a value of the effective bit of each rule in the first rule set, and storing each rule in the first rule set in at least one of S storage units based on the hash key value, where the first rule set is any one of N rule sets, the N rule sets are stored in the S storage units; and when traffic classification is performed, searching for a corresponding rule in each of the S storage units based on a hash key value of a search key.

Abstract: A T cell receptor (TCR) capable of specifically binding to a short peptide KASEKIFYV derived from an AFP antigen. The antigen short peptide KASEKIFYV can form a complex with HLA A0201 and be presented together with same to the cell surface. A nucleic acid molecule encoding the TCR, a vector comprising the nucleic acid molecule, and a cell that transduces the TCR.

Abstract: Disclosed is the application of heptoglycan-chain-containing oligosaccharide compounds in preparation of a vaccine against Helicobacter pylori, belonging to the field of medicine. Different antigen oligosaccharides were obtained by chemical synthesis and fixed onto a chip surface to prepare a synthetic oligosaccharide chip. With animal immunization experiments and synthetic oligosaccharide chip analysis, the antibodies in antiserum produced by Helicobacter pylori polysaccharide immunization are used to determine the structure-activity relationship between the synthetic oligosaccharides and immunogenicity. It is found that the heptoglycan chain in the oligosaccharide compounds is an important immune epitope, and oligosaccharides containing ?-(1?3) heptoglycan chain can be used in preparation and development of vaccines for prevention and treatment of Helicobacter pylori infection.

Abstract: Disclosed herein are methods and systems for identifying targets for distinguishing cell types. In some embodiments, the method comprises: hierarchically clustering expression profiles of cells to generate a dendrogram with each leaf representing the expression profile of a different individual cell. The dendrogram can be pruned by eliminating invalid splits (and their children). The remaining leaves in the dendrogram can be merged, independent of their locations in the dendrogram, based on their distances to one another to generate clusters of expression profiles. The method can identify targets for distinguishing cell types based on targets that are expressed differentially in the clusters.

Abstract: The invention discloses a starch-based multi-channel airflow unit and a preparation method and an application thereof. The preparation method of the present invention comprises the following steps: melting a polylactic acid, wherein a temperature of a first temperature control zone is 135° C. to 145° C., a temperature of a second temperature control zone is 175° C. to 185° C., a temperature of a third temperature control zone is 190° C. to 200° C., and a temperature of a fourth temperature control zone is 175° C. to 185° C.; gelatinizing a starch-based material, adding the starch-based material in the third temperature control zone and fully mixing the mixture; adding a polyol in the third temperature control zone, and fully mixing the mixture; and extruding out the mixed material through twin screws, sizing in vacuum, cooling and sizing, and winding and cutting to obtain the starch-based multi-channel airflow unit.

Abstract: The invention provides a slow-release fragrance and an application thereof in a tobacco product with Chinese-style flavor. The slow-release fragrance of the invention includes the following constituents in percentage by mass: 5% to 50% of a tobacco extract and 50% to 95% of a tangerine peel extract.

Abstract: A T cell receptor (TCR) capable of specifically binding to a short peptide FMNKFIYEI derived from an AFP antigen. The antigen short peptide FMNKFIYEI can form a complex with HLA A0201 and be presented together with same to the cell surface. A nucleic acid molecule encoding the TCR, a vector comprising the nucleic acid molecule, and a cell that transduces the TCR.

Abstract: A cigarette heating device includes a cigarette holder, a heating cavity and a base which are connected in sequence. A top end of the heating cavity is communicated with the cigarette holder, the heating cavity is connected with a power supply device, and the power supply device is disposed at the base. The heating cavity includes a shell and a heating assembly for heating and baking a cigarette, the heating assembly is electrically connected with the power supply device, the shell surrounds an outer side of the heating assembly, and two ends of the shell are connected with the cigarette holder and the base, respectively. An air passage is disposed at a bottom end of the shell, and the heating cavity is communicated with an external environment through the air passage for air to enter and exit the heating cavity.

Abstract: Disclosed is a method for synthesizing an 0-antigen saccharide chain of Helicobacter pylori serotype O:6 using seven glycosylation building blocks. Inexpensive and easily available D-glucosamine, D-galactose, D-mannose and L-fucose are used as starting materials, and seven glycosylation building blocks are obtained through a series of chemical reactions. The saccharide building blocks are then selectively linked together to produce O-antigen oligosaccharide chains of Helicobacter pylori serotype O:6 with different saccharide configuration through a series of glycosylation reactions. Also disclosed is a method to assemble an amino linker at the reducing end of the O-antigen saccharide chain of Helicobacter pylori serotype O:6, and the synthesized oligosaccharide chain with an amino linker can be coupled to a carrier molecule or immobilized on a matrix.

Abstract: The disclosure discloses a glyco-metal-organic frameworks-based hepatic targeted therapeutic drug and a preparation method thereof, and belongs to the field of biomedicine. The disclosure loads a chemotherapeutic drug onto specific metal-organic frameworks, and modifies targeted molecule galactose on the surface of the materials through amide reaction. The biocompatibility and cytotoxicity of the obtained hepatic targeted therapeutic drug have been carefully evaluated at the cellular level. The hepatic targeted therapeutic drug of the disclosure has good stability and acidic pH triggered drug release property, and can exert the synergistic therapeutic effect of photodynamic therapy and chemotherapy. In addition, in vivo behavioral tracing and therapeutic efficacy are evaluated in mouse models with subcutaneous solid tumor and tumor in situ, and the disclosure is expected to play a huge role in clinical applications.

Abstract: An electric heating device having an air channel includes an upper cover component and a lower shell component. A heater component is arranged in a lower shell of the lower shell component, and includes a heater shell, a heating member and a heating member base arranged in the heater shell. A ventilation portion is arranged at a heating member base to guide an air flow to the heating member, and is matched with a first air inlet on the lower shell and a second air inlet on the heater shell. The air flow is led to the heating member from an outside of the lower shell through the first air inlet, the second air inlet, and the ventilation in sequence.

Abstract: The invention discloses a preferable short arc orbit determining method based on Gauss solution cluster, and belongs to the astrodynamics field, including: grouping the observation data, using Gauss method to obtain the target state vector at the corresponding time point for each group of data, forming a solution set of preliminary estimation; dividing the solution set of preliminary estimation into a position component vector solution set and a velocity component vector solution set for clustering to obtain a position component vector solution cluster and a velocity component vector solution cluster; based on the position component vector solution cluster and the velocity component vector solution cluster, generating a two-dimensional trajectory solution set; evaluating each of the two-dimensional trajectories by using a trajectory optimal method, calculating the number of root of orbits corresponding to the optimal two-dimensional trajectory, thereby completing determination of initial orbit.

Abstract: The invention discloses a variable-ventilation filter tip and a cigarette. The filter tip includes a filter element and a coating layer. The coating layer wraps the filter element. The filter element includes a smoke inlet end and a smoke release end. A phase-change ventilation area and a non-phase-change ventilation area are arranged on the coating layer, a plurality of first ventilation holes are arranged in the phase-change ventilation area, and a plurality of second ventilation holes are arranged in the non-phase-change ventilation area. Outside air penetrates through the coating layer through the first ventilation holes and the second ventilation holes to enter a part of the filter element. A part in the filter element close to the smoke inlet end is provided with a starch tube. A phase-change material is filled in the first ventilation hole. A phase-change temperature of the phase-change material ranges from 45° C. to 60° C.

Abstract: A method for generating a preview associated with a media file is provided. The method may include receiving a plurality of social comments associated with a plurality of frames corresponding to the media file. The method may also include storing the received plurality of social comments in a repository, whereby the received plurality of social comments is stored with a frame marker. The method may further include analyzing the stored plurality of social comments. The method may additionally include classifying the analyzed plurality of social comments according to at least one sentiment and at least one keyword in the media file.

Abstract: A starch-based cooling material of the invention is prepared by 8.0 to 9.0 parts of a starch, 0.5 to 1.0 part of a phase change material, and 0.5 to 1.0 a part of polyol. The starch-based cooling material of the invention is prepared by coordination of the starch, the phase change material and the polyol, wherein the phase change material has effects of absorbing and storing heat, a temperature of smoke can be significantly reduced, an effect of fast and strong cooling is realized, and a cooling effect can reach 70° C. to 120° C. All the raw materials for preparing are biodegradable materials, and a prepared heat-not-burn cigarette filter stick can be degraded after use, which is environmental friendly, and can be widely used in the field of preparing heat-not-burning cigarette products.

Abstract: The present invention provides a heat-not-burn tobacco matrix for preventing cut tobacco from falling and an application thereof. The tobacco matrix is formed by disorderly mixing expanded cut tobacco, formula leaf group cut tobacco and/or a tobacco sheet and then rolling, and a density of the tobacco matrix is 0.25 g/cm3 to 0.70 g/cm3.

Abstract: The invention provides a heat-not-burn cigarette product. The heat-not-burn cigarette product of the invention includes a cigarette product and a heater in matched use with the cigarette product. A sucking resistance when the cigarette product and the heater in matched use with the cigarette product are used together is P1, and a sucking resistance of the cigarette product is P2, wherein a ratio of P2/P1 is greater than or equal to 50%.

Abstract: Disclosed is a macrocyclic kinase inhibitor, wherein the compound, or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof is as shown in formula I. Experiments show that the new compound as shown in formula I disclosed in the present invention exhibits an excellent TRK inhibitory activity, has a significant inhibitory effect on TRKA-mutant cell growth, and exhibits an excellent inhibitory effect on in vivo tumor growth, thus providing a new choice for the clinical treatment of diseases associated with abnormal TRK activity.