Abstract: A method for replacing data in a system cache includes obtaining, by the system cache, an access statistics value corresponding to each piece of header data in the system cache, wherein the access statistics value corresponding to the header data represents a difference of the predetermined number of access times of the header data minus the number of times that the header data has been accessed by central processing units (CPUs); obtaining, by the system cache according to the access statistics value corresponding to each piece of header data, header data to be transferred; and transferring, by the system cache, the header data, which is to be transferred, to an external memory.

Abstract: In the field of integrated circuit (IC) design, a method and a bus system for equalizing data information traffic and a decoder are provided. The method includes: receiving data information sent by a device, and allocating at least two transmission interfaces for the data information according to a decoding result of decoding a designated bit in the data information, where the data information carries a device ID, and the designated bit position occupied at least one bit in the device ID; judging whether the data information traffic of the at least two transmission interfaces is balanced; and when the data information traffic of the at least two transmission interfaces is not balanced, switching the designated bit position, and decoding the designated bit after switching, so as to balance the traffic of the at least two transmission interfaces. The bus system includes an interface allocation module, a traffic judging module and a bit position switching module.

Abstract: A holder for a surface contact card includes a receiving frame, a magnetic member, and a tray. The receiving member defines a first receiving space and a latching space. The magnetic member is latched in the latching space. The tray is slidably received in the first receiving space of the receiving frame and is magnetically attracted by the magnetic member. The tray defines a second receiving space configured for receiving the surface contact card.

Abstract: A latching assembly is used in an electronic device. The electronic device includes a first housing and a second housing. The latching assembly includes at least a pair of latching elements and at least a pair of locking elements corresponding to the latching elements. Each latching element includes a hook located in the first housing, and a clasp defined in the second housing. Each locking element includes a catch member and a movable member. The catch member locates in the first housing and facing a corresponding hook. The movable member is received between the catch member and the hook. When each hook clasps a corresponding clasp to engage the first housing and the second housing, the movable member moves to the second housing to be caught by the catch member and the hook, allowing the movable member to limit the movement of the hook relative to the clasp.

Abstract: The present invention proposes a method for doubly backing up files asynchronously, wherein at least two first network elements share a second network element, both of said first network elements include respectively an active file handling device and a standby file handling device, characterized in that, said active file handling device copies the files to the second network element, if said standby file handling device finds that said active file handling device misses the files, said standby file handling device copies backups of the files to said active file handling device, thus the files stored in said active file handling device and the files stored in said standby file handling device being synchronized.

Abstract: The present invention relates to polymeric conjugates of adenine nucleoside analogs. In particular, the invention relates to multi-arm polyethylene glycol conjugates of adenine nucleoside analogs and use thereof. The present invention, more specifically, provides polymeric conjugates of toyocamycin and its derivatives. Furthermore, the present invention provides a method for preparing the polymeric conjugates of adenine nucleoside analogs and a method of using the same for treating a cancer, inhibiting the growth or proliferation of cancer cells, treating a viral infection, treating a disease or condition associated with abnormal expression of VEGF. Most polymeric conjugates of toyocamycin was stable in PBS but released toyocamycin in vivo to provided inhibition of cancer cell growth.

Abstract: An advanced extensible interface (AXI) bus is disclosed. 2×2 AXI crossbars are used as basic units; each including two slave interfaces and two master interfaces; an N2 full Mesh fabric is built by using the basic units, so that each slave interface on one basic unit is connected to a master interface on another basic unit to form a first path. A data transmission method includes: receiving, through a master interface of a basic unit, a data packet sent by a master device; sending, through a slave interface of the basic unit, the data packet to a destination slave device by using an AXI bus; receiving, through the slave interface of the basic unit, a response packet returned by the destination slave device, where the basic units are 2×2 AXI crossbars and the AXI bus is based on an N2 full mesh fabric built by using the basic units.

Abstract: The present invention relates to releasable urea linker systems involving amine-containing chemical compounds and biologically active agents. In particular, the present invention relates to reversibly releasable linkers based on intramolecular cyclization-assisted releasable urea linkages to aromatic amine-containing compounds. The present invention also relates to polymeric conjugates of indolinone-based tyrosine kinase inhibitors.

Abstract: In the field of integrated circuit (IC) design, a method and a bus system for equalizing data information traffic and a decoder are provided. The method includes: receiving data information sent by a device, and allocating at least two transmission interfaces for the data information according to a decoding result of decoding a designated bit in the data information, where the data information carries a device ID, and the designated bit position occupied at least one bit in the device ID; judging whether the data information traffic of the at least two transmission interfaces is balanced; and when the data information traffic of the at least two transmission interfaces is not balanced, switching the designated bit position, and decoding the designated bit after switching, so as to balance the traffic of the at least two transmission interfaces. The bus system includes an interface allocation module, a traffic judging module and a bit position switching module.

Abstract: A system on chip (soc) and A transmission method under Advanced eXtensible Interface (AXI) bus are disclosed. The system includes a master device, a first extending module, a first interconnection structure, a first subtracting module, a second interconnection structure, and a slave device. The first extending module is configured to add N bits into an identifier (ID) carried in a transmission request, where N is equal to a sum of bits added by all interconnection structures in a longest loop of a system into the ID carried in the transmission request that passes through the interconnection structures.

Abstract: The present invention is directed to nucleic acids delivery systems and methods of modulating an expression of a target gene using the same. In particular, the invention relates to nucleic acids conjugates containing an endosomal release-promoting moiety. The nucleic acids conjugates further contain a nuclear localization signal moiety, and/or a cell targeting moiety.

Abstract: The present invention is directed to methods of preparing linear polymers such as polyalkylene oxides containing a terminal amine in high purity. One preferred method includes reacting a polyalkylene oxide such as polyethylene glycol containing a terminal azide with a phosphine-based reducing agent such as triphenylphosphine or an alkali metal borohydride reducing agent such as sodium borohydride in a solvent to reflux. The resultant polymer-amines are of sufficient purity so that expensive and time consuming purification steps required for pharmaceutical grade polymers are avoided.

Abstract: The present invention proposes a method for doubly backing up files asynchronously, wherein at least two first network elements share a second network element, both of said first network elements include respectively an active file handling device and a standby file handling device, characterized in that, said active file handling device copies the files to the second network element, if said standby file handling device finds that said active file handling device misses the files, said standby file handling device copies backups of the files to said active file handling device, thus the files stored in said active file handling device and the files stored in said standby file handling device being synchronized.

Abstract: The present invention provides polymeric linkers containing pyridyl disulfide moieties. Methods of making the polymeric linkers and methods of making conjugates using the same are also disclosed.

Abstract: The present invention provides polymeric conjugates containing positively charged moieties. Methods of making the polymeric delivery systems and methods of treating mammals using the same are also disclosed.

Abstract: The present invention is directed to methods of preparing linear polymers such as polyalkylene oxides containing a terminal amine in high purity. One preferred method includes reacting a polyalkylene oxide such as polyethylene glycol containing a terminal azide with a phosphine-based reducing agent such as triphenylphosphine or an alkali metal borohydride reducing agent such as sodium borohydride in a solvent to reflux. The resultant polymer-amines are of sufficient purity so that expensive and time consuming purification steps required for pharmaceutical grade polymers are avoided.

Abstract: The present invention is directed to methods of preparing linear polymers such as polyalkylene oxides containing a terminal amine in high purity. One preferred method includes reacting a polyalkylene oxide such as polyethylene glycol containing a terminal azide with a phosphine-based reducing agent such as triphenylphosphine or an alkali metal borohydride reducing agent such as sodium borohydride in a solvent to reflux. The resultant polymer-amines are of sufficient purity so that expensive and time consuming purification steps required for pharmaceutical grade polymers are avoided.

Abstract: The present invention is directed to methods of preparing linear polymers such as polyalkylene oxides containing a terminal amine in high purity. One preferred method includes reacting a polyalkylene oxide such as polyethylene glycol containing a terminal azide with a phosphine-based reducing agent such as triphenylphosphine or an alkali metal borohydride reducing agent such as sodium borohydride in a solvent to reflux. The resultant polymer-amines are of sufficient purity so that expensive and time consuming purification steps required for pharmaceutical grade polymers are avoided.

Abstract: The present invention is directed to methods of preparing linear polymers such as polyalkylene oxides containing a terminal amine in high purity. One preferred method includes reacting a polyalkylene oxide such as polyethylene glycol containing a terminal azide with a phosphine-based reducing agent such as triphenylphosphine or an alkali metal borohydride reducing agent such as sodium borohydride in a solvent to reflux. The resultant polymer-amines are of sufficient purity so that expensive and time consuming purification steps required for pharmaceutical grade polymers are avoided.