Abstract: Provided herein are compounds (e.g., compounds of Formula (I)), their mechanism of action, and methods of treating diseases and disorders (e.g., cancer) using the compounds provided herein (e.g., compounds of Formula (I)). Also disclosed herein are N methods of inhibiting and degrading kinases (e.g., CDK9, CDK10, or anaplastic lymphoma kinase).

Abstract: Certain aspects of the present disclosure provide techniques for updated system information (SI) delivery. In some cases, a method performed by a user equipment may include receiving, from a network entity, a configuration for a common control resource set (CORESET) on a first downlink bandwidth part (BWP) and a configuration for one or more common search space (CSS) sets within the common CORESET for physical downlink control channel (PDCCH) monitoring. The method may further include receiving, from the network entity on the first downlink BWP, a first set of system information (SI) scheduled by a physical downlink control channel (PDCCH) in the one or more CSS sets, and receiving, from the network entity on a second downlink BWP, updated SI or an indication of updated SI.

Abstract: Disclosed in the present invention is a method for preparing high-purity losartan, which belongs to the fields of medicine and chemical engineering. The losartan is obtained by means of a multi-stage temperature reaction in the presence of a catalyst and sodium azide, wherein the temperature in the first stage of the multi-stage temperature reaction is higher than that in the second stage. According to the method, the generation of dimer impurities can be reduced, and the risk of impurities being introduced into a finished losartan potassium product is reduced.

Abstract: Methods, apparatuses, and computer-readable storage medium for supporting mobile-originated small data transmission (MO-SDT) and mobile-terminated small data transmission (MT-SDT) or point-to-multi-point (P2M) multicast and broadcast services (MBS) are provided. An example method may include transmitting, to a base station, a capability indication representing support of MO-SDT and MT-SDT. The example method may further include receiving, from the base station, one or more configurations for the MO-SDT and the MT-SDT in a radio resource control (RRC) message, the RRC message comprising at least an RRC release message. The example method may further include transitioning to an RRC inactive state. The example method may further include transmitting, to the base station, a common control channel (CCCH) message in a MO-SDT transmission while in the RRC inactive state.

Abstract: Described herein is N-[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]-4-[[3(R)-[(1-oxo-2-propen-1-yl)amino]-1-piperidinyl]methyl]-2-pyridinecarboxamide (Compound A) (Formula I), including crystalline forms, solvates, and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions or pharmaceutical formulations that include the compound, as well as methods of using the compound, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, diabetes, and inflammatory diseases or conditions.

Abstract: A method and system for exploring hidden karst pipelines, mainly comprising: determining an upstream and a downstream of an underground karst pipeline; laying a grounding electrode at the upstream and the downstream respectively; establishing an electromagnetic emission system through underground karst water channels in the underground karst pipeline in a survey area, a transmitter and a generator; arranging a receiving system through an air mobile equipment towing a receiver as a receiving end; turning on the electromagnetic emission system; a generator supplying power to emission circuit; controlling the air mobile equipment to move along routes to collect signal continuously above the survey area, to complete an area-based measurement, and obtain observed data in the whole survey area; processing the observed data; delineating a concrete distribution of the underground karst water channels from the to the, such as a net-shaped path diagram or a tree-shaped path diagram.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may receive a UE-specific configured grant (CG) small data transmission (SDT) configuration with parameters specific to CG-SDT in a non-terrestrial network (NTN). The UE may receive system information associated with validation of the parameters for CG-SDT on the NTN. The UE may transmit an SDT to a network entity of the NTN using one or more of the parameters. Numerous other aspects are described.

Abstract: A sample mounting device for direct tensile test of rock mass is provided, which includes a first positioning stage, a second positioning stage, a first support piece, a second support piece, and a screw drive mechanism. The second positioning stage is arranged above the first positioning stage and capable of moving up and down, and cushion blocks for gluing with the rock mass are coaxially and detachably arranged at opposite ends of the first positioning stage and the second positioning stage, and a rock mass mounting area is formed between the two cushion blocks. A screw of the screw drive mechanism includes a first thread segment and a second thread segment with opposite thread directions. The first support piece is connected with the first thread segment through a nut seat, and the second support piece is connected with the second thread segment through a nut seat.

Abstract: The present disclosure provides anti-TIM-3 antibodies or antigen-binding fragments thereof, isolated polynucleotides encoding the same, pharmaceutical compositions comprising the same, and the uses thereof.

Abstract: The present invention discloses a manufacturing method of a photovoltaic solar cell module, and belongs to the technical field of solar photovoltaic device manufacturing. In the present invention, a metal connecting ribbon is adopted for connecting a cell, and front and rear surfaces of the cell are designed by removing PAD dots, so that optical shielding on a surface of the cell is reduced, and the cost is reduced. The metal connecting ribbon and the cell are welded into a cell string by a jig and a manipulator and the risk of unstable connection is substantially eliminated by providing an adhesive pattern on the metal connecting ribbon of the cell string and curing.

Abstract: An ultra-long silver nanowire material and a fabrication method thereof are provided. The fabrication method includes the following steps: step 1: adding a reducing sugar and polyvinylpyrrolidone (PVP) to deionized water to obtain a clear solution; step 2: mixing the clear solution with a metal ion solution to obtain a mixed solution A; step 3: mixing the mixed solution A with a halide solution to obtain a mixed solution B; step 4: adding a silver ion-containing solution dropwise to the mixed solution B to obtain a reaction solution and conducting a reaction at 110° C. to 130° C. for 14 h to 20 h to obtain a flocculent product; and step 5: subjecting the flocculent product to sedimentation washing with deionized water and absolute ethanol successively to obtain the ultra-long silver nanowire material. The fabrication method of the present disclosure is low in cost, environmentally friendly, and conducive to industrial production.

Abstract: A chromic liquid capable of responding to and reproducing external optical color illumination is formed as a TiO2 colloid imbued with three sensitizing dyes. The dyes are (a) SQ2 (5-carboxy-2-[[3-[(2,3-dihydro-1,1-dimethyl-3-ethyl-1H-benzo[e]indol-2-ylidene)methyl]-2-hydroxy-4-oxo-2-cyclobuten-1-ylidene]methyl]-3,3-dimethyl-1-octyl-3H-indolium), (b) LEG4 (3-{6-{4-[bis(2?,4?-dibutyloxybiphenyl-4-yl)amino-]phenyl}-4,4-dihexyl-cyclopenta-[2,1-b:3,4-b?]dithiophene-2-yl}-2-cyanoacrylic acid) and (c) L0 (4-(diphenylamino) phenylcyanoacrylic acid). The liquid reproduces cyan, magenta and yellow color or a mixture thereof in response to exposure to illumination by light of various colors.

Abstract: The present invention discloses a method for manufacturing a novel busbarless solar photovoltaic module and relates to the technical field of solar photovoltaic device manufacturing. The present invention uses a metal connecting ribbon to connect a cell and the front and back of the cell are designed to remove PAD points, which reduces optical occlusion on the surface of the cell and costs, and by using fixtures and manipulators to weld the metal connecting ribbon and the cell into a cell string and by applying and curing an adhesion point on the metal connecting ribbon of the cell string, the risk of unstable connection is completely eliminated. In addition, the requirement for alignment between the metal connecting ribbon and a finger of the cell is reduced, thereby simplifying the manufacturing process of the cell string.

Abstract: A method for synchronous extraction and analysis of multiple trace emerging organic contaminants in hairs, and application comprises the following steps: S1, pretreatment; S2, mixing and extraction; S3, nitrogen blowing concentration and purification; and S4, low-temperature separation. A device for synchronous extraction and analysis of multiple trace emerging organic contaminants in hairs, and application comprises comprises a treatment barrel, a pedestal and a drive assembly. This method is applied to a study on long-term exposure of multiple organic contaminants in a human body. According to the present disclosure, an extraction solution extracting system is established, 5 emerging organic contaminants in hairs can be purified and analyzed by establishing a dispersion solid-phase extraction filler consisting of Na2SO4 powders and C18 powders.

Abstract: Herein is high availability for online transaction processing with redundancy and redo for a federation of pluggable databases and container databases. In a federation of container database management systems that includes a first container database, first redo data of a first pluggable database in a second container database is obtained based on a database dictionary in the first container database. To the first pluggable database in the first container database, the first redo data of the first pluggable database in the second container database is applied. Based on the database dictionary in the first container database, second redo data of a second pluggable database in a third container database is obtained. To the second pluggable database in the first container database, without modifying content of the first pluggable database in the first container database, the second redo data of the second pluggable database in the third container database is applied.

Abstract: Herein is high availability for online transaction processing with redundancy and redo for a federation of pluggable databases and container databases. In an embodiment of a federation of container database management systems that includes a first container database, first redo data of a first pluggable database in a second container database is obtained based on a database dictionary in the first container database. To the first pluggable database in the first container database, the first redo data of the first pluggable database in the second container database is applied. Based on the database dictionary in the first container database, second redo data of a second pluggable database in a third container database is obtained. To the second pluggable database in the first container database, without modifying content of the first pluggable database in the first container database, the second redo data of the second pluggable database in the third container database is applied.

Abstract: An adjustable gas system for a firearm includes a one-piece gas block body, configured to be fixed to a barrel of the firearm, and a partial annular gas regulator. The gas block includes a gas flow hole that receives a gas tube of the firearm. The gas block body also includes a gas block body bulge and a ring at one end of the gas flow hole. The gas block body clamps to a barrel of the firearm by: (i) set screw(s), and (ii) direct/physical contact of the gas block body bulge and the ring. The gas regulator, when installed on the barrel, rotatably and partially surrounds the barrel such that, as the gas regulator is rotated around the barrel from a first position to a second position, a diameter of a resultant gas port hole changes as controlled by allocation holes on the gas regulator.

Abstract: An ultra-long silver nanowire material and a fabrication method thereof are provided. The fabrication method includes the following steps: step 1: adding a reducing sugar and polyvinylpyrrolidone (PVP) to deionized water to obtain a clear solution; step 2: mixing the clear solution with a metal ion solution to obtain a mixed solution A; step 3: mixing the mixed solution A with a halide solution to obtain a mixed solution B; step 4: adding a silver ion-containing solution dropwise to the mixed solution B to obtain a reaction solution and conducting a reaction at 110° C. to 130° C. for 14 h to 20 h to obtain a flocculent product; and step 5: subjecting the flocculent product to sedimentation washing with deionized water and absolute ethanol successively to obtain the ultra-long silver nanowire material. The fabrication method of the present disclosure is low in cost, environmentally friendly, and conducive to industrial production.

Abstract: Embodiments of this specification provide for generating dialogue annotation data. A method includes: obtaining grammar that has been pre-generated in a target scenario, the grammar including a first phrase and a second phrase; the first phrase includes a first intent operation and a first variable of a first intent, where the first variable invokes other phrases. The second phrase assigns a value to the first variable and includes a property acquisition operation and a second variable of a second intent. Generating a target meaning representation of nested phrases for simulating a certain human-machine dialogue by invoking the first phrase and the second phrase in the grammar. Performing the first intent operations based on a property value corresponding to the first variable of the second variable assigned to the first variable.

Abstract: Embodiments are disclosed for receiving a modal input including at least one of a text input or an image input. The method may include extracting an intent label from the modal input. The method may further include generating, by an intent embedding generator, an intent embedding from the intent label. The method may further include comparing the intent embedding to a plurality of candidate font embeddings to obtain one or more candidate fonts based on a similarity of the intent embedding to the plurality of candidate font embeddings in an embedding space. The method may further include identifying a recommended font based on the similarity of the intent embedding to a selected candidate font embedding of the plurality of candidate font embeddings.