Abstract: A method and a device for the detection of transglutaminases, in particularly of blood coagulation factor XIII (FXIII). The method is based on a rapid, point-of-care compatible test principle for transglutaminases and allows an exact determination of FXIII in a short time and with simple handling.

Abstract: The present invention relates to a method for stabilizing an enzyme by storing the enzyme in the presence of a stable coenzyme. The present invention further relates to an enzyme stabilized with a stable coenzyme, and to the use thereof in test elements for detecting analytes.

Abstract: Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device.

Abstract: Methods, devices and systems for detecting an analyte in a body fluid are described. A sample of body fluid is applied to a test element having a test field including a test material adapted to change a measurable property in the presence of the analyte. The test element includes a capillary to guide the sample across said test field. The measurable property is measured in a first measurement location providing a first measurement value, and in a second measurement location providing a second measurement value. The analyte is detected by using an evaluation algorithm having at least a first input variable including a difference between the first measurement value and the second measurement value, and at least a second input variable including information relating to an analyte-induced change of the measurable property of the test material in at least part of the test field.

Abstract: Methods for detecting an analyte in a body fluid are described as well as devices and systems adapted for performing such methods. In embodiments of the method, a sample of body fluid is applied to a test element having at least one test field including at least one test material that is adapted to change at least one measurable property in the presence of the analyte. The test element further includes a capillary to guide the sample across said test field in a flow direction. The test element also includes first and second measurement locations offset from each other in the flow direction. The measurable property is measured in at least one first measurement location, providing at least one first measurement value, and it is measured in at least one second measurement location, providing at least one second measurement value.

Abstract: A method for determining the concentration of an analyte in a sample, and to a test strip and a kit for carrying out said method, and a test system having said test strip and a detector. The use of the method to determine the concentration of an analyte in a sample.

Abstract: Disclosed is a puncturing system for generating a puncture wound for obtaining a sample of a body fluid, comprising a press-on part to be pressed onto a body part in which a puncture wound is to be generated, a trigger, by the actuation of which a user can trigger a puncturing motion of a puncturing element after the press-on part is pressed on, and a testing facility for determining at least one test parameter on which a sample-obtaining probability depends. A securing facility is also provided that, in a locked state, locks the trigger such that no puncturing motion can be triggered, and, in a triggering state, releases the trigger such that a puncturing motion can be triggered by actuation thereof, whereby the securing facility is transitioned from the locked state to the triggering state by the testing facility when the test parameter determined by the testing facility meets defined minimum requirements.

Abstract: Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device.

Abstract: The present invention provides for stable nicotinamide adenine dinucleotide (NAD/NADH) and nicotinamide adenine dinucleotide phosphate (NADP/NADPH) derivatives of formula (I), enzyme complexes of these derivatives and their use in biochemical detection methods and reagent kits.

Abstract: Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device.

Abstract: The present invention relates to a method for stabilizing an enzyme by storing the enzyme in the presence of a stable coenzyme. The present invention further relates to an enzyme stabilized with a stable coenzyme, and to the use thereof in test elements for detecting analytes.

Abstract: The present invention relates to a method for stabilizing an enzyme by storing the enzyme in the presence of a stable coenzyme. The present invention further relates to an enzyme stabilized with a stable coenzyme, and to the use thereof in test elements for detecting analytes.

Abstract: A test instrument for analyzing body fluids such as blood or urine. The instrument includes a wound test tape which can be transported from a storage space into a waste space by advancing the tap. The test tape has a plurality of test sections to which body fluid can be applied at a receiving position and also includes a measuring unit for detecting a constituent of the body fluid on an active test section. In order to carry out auxiliary instrument functions, in addition to the test sections, the test tape has one or more functional sections which can be brought into a functional position by advancing the tape.

Abstract: The invention also relates to compounds, which are useful for intra-molecular fluorescence resonance energy transfer (FRET), comprising the oxidized form of a carbaNADH-based first fluorophore and a second fluorophore that is excitable at a wave-length of between 445 to 540 nm and that has an emission maximum of greater than 560 nm, and methods, kits and compositions related thereto.

Abstract: The invention relates to the field of integrated systems which comprise a test element and a lancet which can be firstly used to make a wound in a skin opening in order to collect a sample. The sample is subsequently directly taken up by the test element in the process of which it comes into contact with a reagent contained in the test element and results in an optically detectable change in a test field. The change in the test field is detected by means of an analytical unit which is optically contacted with the test field via at least one light-conducting element.

Abstract: A test instrument for analyzing body fluids such as blood or urine. The instrument includes a wound test tape which can be transported from a storage space into a waste space by advancing the tap. The test tape has a plurality of test sections to which body fluid can be applied at a receiving position and also includes a measuring unit for detecting a constituent of the body fluid on an active test section. In order to carry out auxiliary instrument functions, in addition to the test sections, the test tape has one or more functional sections which can be brought into a functional position by advancing the tape.

Abstract: A test instrument for analyzing body fluids such as blood or urine. The instrument includes a wound test tape which can be transported from a storage space into a waste space by advancing the tap. The test tape has a plurality of test sections to which body fluid can be applied at a receiving position and also includes a measuring unit for detecting a constituent of the body fluid on an active test section. In order to carry out auxiliary instrument functions, in addition to the test sections, the test tape has one or more functional sections which can be brought into a functional position by advancing the tape.

Abstract: The present invention provides for stable nicotinamide adenine dinucleotide (NAD/NADH) and nicotinamide adenine dinucleotide phosphate (NADP/NADPH) derivatives of formula (I), enzyme complexes of these derivatives and their use in biochemical detection methods and reagent kits.

Abstract: The invention relates to a lancet, which has a lancet tip at a front end and which on an upper face comprises a contact surface for placing a test element thereon and at least one channel for receiving a sample, wherein an upwardly open section of the channel runs in the contact surface. According to the invention, the channel has another upwardly open channel section which runs on the upper face of the lancet in or adjacent to a surface area that is lower than the contact surface, wherein the contact surface is arranged between the lancet tip and the lower surface area. The invention further relates to a system comprising such a lancet and a test element, and to a method for transferring a liquid sample from a channel of a lancet which is designed as a groove or slot to a test element.

Abstract: The present invention provides for stable nicotinamide adenine dinucleotide (NAD/NADH) and nicotinamide adenine dinucleotide phosphate (NADP/NADPH) derivatives of formula (I), enzyme complexes of these derivatives and their use in biochemical detection methods and reagent kits.