Abstract: Strands of material may be intertwined using weaving techniques, knitting techniques, non-woven or entanglement techniques, or braiding techniques. Fabric that is formed from the strands of material may be used in forming a fabric-based item. The fabric based item may include electrical components. The strands may include conductive strands that form signal paths. The signal paths can carry electrical signals associated with operation of the electrical components. Each strand may have an elongated core and a coating. Strands may also include intermediate layers between the cores and coatings. The cores, intermediate layers, and coatings may be formed from polymer without conductive filler, polymer with conductive filler, and/or metal. A polymer core may be provided with recesses to help retain subsequently deposited layers such as a metal coating layer. The recesses may be grooves that extend along the longitudinal axis of the core.

Abstract: The present invention relates to new extended release pharmaceutical compositions and methods of use thereof for the treatment of disorders.

Abstract: A motion tracking system for dynamic tracking of and compensation for motion of a patient during a magnetic resonance scan comprises a first camera positioned to view an optical marker along a first line of sight; a second camera positioned to view the optical marker along a second line of sight; and a computer system configured to analyze images generated by the first and second cameras to determine changes in position of the optical marker, and to generate tracking data for use by a magnetic resonance scanner to dynamically adjust scans to compensate for the changes in position of the optical marker, wherein the computer system is configured to dynamically adapt its image analysis to utilize images from all cameras that are currently viewing the optical marker.

Abstract: A spinneret, apparatus, and method are provided for making filaments for fibrous nonwoven fabrics with more uniform filament and fabric formation while minimizing filament breaks and hard spot defects in webs and fabrics made therefrom. The spinneret has a spinneret body that has an overall length to hydraulic diameter ratio and defines orifices that extend through the spinneret body, wherein the orifices comprise capillaries that open at a face of the spinneret body for polymer filament extrusion therefrom, wherein the capillaries are arranged in a plurality of different rows at the face of the spinneret body, and wherein the plurality of different rows are arranged into a plurality of different zones at the face of the spinneret body.

Abstract: A data processing method and apparatus, the method comprising: storing, at a first memory location in a memory, a first copy of a set of data; storing, at a second memory location in a memory, a second copy of a set of data; comparing the first copy to the second copy so as to identify, within the first copy, a pointer, the pointer being located at a first data element of the first copy, the pointer specifying a second data element of the first copy; determining an offset for the identified pointer, the offset specifying a number of data elements between the first data element and the second data element; and modifying the first copy such that the pointer within the first copy specifies the second data element using only the first data element and the offset.

Abstract: A control system for a work vehicle includes a controller, a processor, and a memory that causes the processor to receive, via a sensor assembly, sensor signals and convert the sensor signals into a plurality of entries of a full measurement vector. The memory devices causes the processor to determine a first state vector using IMU Kalman filter, update a first subset of entries the full state vector, determine a second state vector using a spatial positioning Kalman filter, update a second subset of entries the full state vector based on the second state vector, determine a third state vector using a vehicle Kalman filter, update a third subset of entries of the plurality of entries of the full state vector based on the third state vector, and control movement of the work vehicle based on at least one of the first state vector, the second state vector, the third state vector, and the full state vector.

Abstract: A system of connecting a stiffener to the sidewall of a grain bin using a stud bolt having a first threaded end, a second threaded end and a feature positioned between the first end and a second end. A sealing member is positioned over the first end of the stud bolt, which in one case is a metallic washer with an affixed compressible sealing member. The first end of the stud bolt is inserted into a hole in the sidewall and an inner nut is placed over the first end inside the sidewall. As the inner nut is tightened, the feature is pulled toward the exterior surface of the grain bin thereby causing the sealing member to form a seal with the exterior surface of the grain bin. The second end of the stud bolt is inserted into a hole in the stiffener which is tightened onto the stud bolt.

Abstract: Systems and method for providing a single sign in a gaming console that associates online activity that is out-of-game/cross game, and/or online activity that is in-game, and/or activity that is offline and in-game with that account. While online, a service tracks activity of gamers and provides usage statistics in a profile. While offline, the game console tracks the player's activity via a mechanism to collect detailed information about a specific player's in-game statistics and accomplishments. The offline activity is cached and uploaded when the console connects to the online service. Players can accumulate achievements offline that are credited towards online activities.

Abstract: A portable power drill (11) is disclosed having a chuck or drill collar (14) at one end and a substantially cylindrical (or frusto-conical) twist throttle handle (25, 125, 225) at the other end. Rotation of the handle in the direction of forward rotation of the chuck decreases the drill speed and, conversely, rotation of the handle in the direction of reverse rotation of the chuck increases the drill speed. Consequently, in the event of an auger locked in the chuck becoming jammed, the reaction forces experienced by the drill unit rotate the drill unit in a direction such that throttle decreases the drill speed. In addition, the drill unit is provided with forward (44) and reverse gears (45) and a forward/reverse selection mechanism (48, 50, 51) which is actuated by a forward force, or a withdrawing force respectively being applied to the drill unit via an operator who holds the handles (20, 25) of the drill unit.

Abstract: This invention relates to and orthopaedic implant having an expansion means adapted to increase the external surface area of the implant, the expansion means positioned to correspond to voids or depressions in the anatomy of a patient. Also described are method for the design and manufacture of such implants.

Abstract: A system for tracking a moving target having up to six degrees of freedom and rapidly determining positions of the target, said system includes an easy to locate precision optical target fixed to the target. This system includes at least two cameras positioned so as to view the optical camera from different directions with each of the at least two cameras being adapted to record two dimensional images of the precision optical target defining precise target point. A computer processor is programmed to determine the target position of x, y and z and pitch, roll and yaw. In an embodiment, the system can be configured to utilize an iteration procedure whereby an approximate first-order solution is proposed and tested against the identified precise target points to determine residual errors which can be divided by the local derivatives with respect to each component of rotation and translation, to determine an iterative correction.

Abstract: A method of making a core metal element for a medical guidewire including providing a wire of nickel titanium alloy having a length that includes a proximal portion having a first diameter and a distal portion having a second diameter. The method further includes applying cold work to the distal portion and not applying cold work to the proximal portion, thereby imparting to the distal portion a third diameter that is smaller than the second diameter; and then applying a reducing process to the wire whereby the proximal portion is reduced to have a fourth diameter that is less than the first diameter.

Abstract: A motion compensation system for tracking and compensating for patient motion during a medical imaging scan comprises an optical marker comprising an optically visible pattern and a mounting portion; a first optical detector positioned to digitally image the optically visible pattern along a first line of sight; a second optical detector positioned to digitally image the optically visible pattern along a second line of sight; a tracking engine configured to determine a pose of the object in six degrees of freedom by analyzing images from the first and second optical detectors; and a controller interface configured to generate tracking information based on the pose and to electronically transmit the tracking information to a scanner controller to enable compensation within a medical imaging scanner for object motion.

Abstract: Strands of material may be intertwined using weaving techniques, knitting techniques, non-woven or entanglement techniques, or braiding techniques. Fabric that is formed from the strands of material may be used in forming a fabric-based item. The fabric based item may include electrical components. The strands may include conductive strands that form signal paths. The signal paths can carry electrical signals associated with operation of the electrical components. Each strand may have an elongated core and a coating. Strands may also include intermediate layers between the cores and coatings. The cores, intermediate layers, and coatings may be formed from polymer without conductive filler, polymer with conductive filler, and/or metal. A polymer core may be provided with recesses to help retain subsequently deposited layers such as a metal coating layer. The recesses may be grooves that extend along the longitudinal axis of the core.

Abstract: A spinneret, apparatus, and method are provided for making filaments for fibrous nonwoven fabrics with more uniform filament and fabric formation while minimizing filament breaks and hard spot defects in webs and fabrics made therefrom. The spinneret has a spinneret body that has an overall length to hydraulic diameter ratio and defines orifices that extend through the spinneret body, wherein the orifices comprise capillaries that open at a face of the spinneret body for polymer filament extrusion therefrom, wherein the capillaries are arranged in a plurality of different rows at the face of the spinneret body, and wherein the plurality of different rows are arranged into a plurality of different zones at the face of the spinneret body.

Abstract: The present invention provides methods and compositions for inducing expression of Ube3a in a cell by contacting the cell with a topoisomerase inhibitor. Particular embodiments include a method of treating a genomic imprinting disorder, such as Angelman syndrome, in a subject by administering to the subject an effective amount of a topoisomerase inhibitor.

Abstract: A method and apparatus for generating, in an aircraft in flight, a feasibility display indicative of the feasibility of a weapon, the method comprising: providing a performance envelope for the weapon; determining, using the performance envelope, configuration data for configuring a generic algorithm; uploading the configuration data to the aircraft; generating feasibility data N indicative of the feasibility of a weapon carried on the aircraft successfully engaging a target and/or the feasibility of a weapon carried on the target successfully engaging the aircraft; determining, on board the aircraft, using the same generic algorithm and the uploaded configuration data, one or more test criteria; performing, on board the aircraft, an assessment process including determining whether or not the feasibility data satisfies the one or more test criteria; and, based the assessment, using the feasibility data, generating the feasibility display.

Abstract: The present invention relates to new extended release pharmaceutical compositions and methods of use thereof for the treatment of disorders.

Abstract: Methods of increasing the biological activity of toxins. Methods of increasing the biological activity of pesticide toxins through the incorporation of pro-regions into nucleic acid constructs for the production of said toxins.

Abstract: This invention relates to and orthopedic implant having an expansion means adapted to increase the external surface area of the implant, the expansion means positioned to correspond to voids or depressions in the anatomy of a patient. Also described are method for the design and manufacture of such implants.