Abstract: Anatomical and functional assessment of coronary artery disease (CAD) using machine learning and computational modeling techniques deploying methodologies for non-invasive Fractional Flow Reserve (FFR) quantification based on angiographically derived anatomy and hemodynamics data, relying on machine learning algorithms for image segmentation and flow assessment, and relying on accurate physics-based computational fluid dynamics (CFD) simulation for computation of the FFR.

Abstract: An exhaust conduit for a glass melt system includes a corrosion resistant refractory conduit material, such as a conduit material including zirconia. The conduit can extend through a relatively dense refractory block material, such as a refractory block comprising alumina. The exhaust conduit can exhibit improved corrosion resistance in processing a variety of glass melt compositions.

Abstract: An automated system and method for BUYING AND SELLING STOCKS, FRACTIONAL SHARES, SHARES, COMMODITIES, OR ANY OTHER PRODUCT LISTED ON ANY US OR GLOBAL STOCK EXCHANGES through a kiosk of debit card, credit card, or gift card. The kiosk having a housing to house electrical, network, and communication components; a user interface in communication with the kiosk, the user interface to receive user commands; the kiosk being managed and operated by an investment entity, the investment entity having the ability to buy or sell the one or more investments; and a gift card; the one or more investments include one or more stocks, fractional shares, shares, commodities, or any other product listed on any US or global stock exchanges; and the one or more user commands allow the user to purchase or sell the one or more investments via the kiosk.

Abstract: The present invention relates to new extended release pharmaceutical compositions and methods of use thereof for the treatment of disorders.

Abstract: A system for obtaining a desired cooling effect that utilizes a water-soluble endothermic salt solution and pure water. The cooling effect is created by cycling between two phases, a refrigeration phase and a dehydration phase. In the refrigeration phase, a water-soluble endothermic salt solution is used as a refrigerant to absorb heat by pumping through a first heat exchanger which cools an object or an area. In the dehydration phase, the cooling process is regenerated by pumping the now heated endothermic salt solution through a distillation membrane, where the solution and pure water are continuously commingled and separated from one another through a distillation membrane to optimize the thermodynamic efficiency of the system. At least two pumps provide the motive energy to move the endothermic salt and pure water through the closed loop piping system. The concentrated salt solution leaving the distillation membrane is further cooled using a second heat exchanger to facilitate crystal formation.

Abstract: The present invention relates to conjugation-competent albumins and albumin-related polypeptides, and their conjugates with at least one moiety, and to polynucleotides encoding them.

Abstract: An anthropomorphic test device utilizes a mounting mechanism for coupling a hollow member including a simulated flesh to a support structure, with the simulated flesh including a foam core portion covered with a skin portion. The mounting mechanism includes inserts, such as plastic or metal inserts having a flange portion and an elongated tubular member, which are introduced in multiple places within the simulated flesh with the flange portion within the foam core portion and the elongated tubular member extending through the skin portion. A fastening member is inserted through an elongated opening in the insert and within a receiving cavity portion of the support structure to secure the hollow member to the support structure. The hollow member may be a hollow pelvic member, and the support structure may be a pelvic support structure, with the hollow pelvic member secured to the pelvic support structure via the mounting mechanism.

Abstract: A percussion instrument strike training applique is formed as a multi-layer removable sticker that covers a percussion instrument playing/striking zone. The multi-layer sticker has a detachable ink layer on a top surface of the applique that detaches when struck with a striking implement of the instrument. The detachment of the detachable ink layer from the striking surface of the instrument allows the percussion instrument players to assess their performance when they are not playing and are free to think critically and make adjustments.

Abstract: A safety door latch system is presented for a grain bin having a door frame. An inner door is connected to the door frame that is configured to move between an open position and a closed position. An outer door is connected to the door frame and is configured to move between an open position and a closed position. A safety mechanism is connected to the door frame and is configured to move between an open position and a closed position. When the inner door frame is moved to a closed position, a portion of the inner door engages the safety mechanism thereby causing the safety mechanism to move to the closed position. When the safety mechanism is in the closed position, the outer door may be latched to the safety mechanism. When the safety mechanism is in the open position, the outer door cannot latch to the safety mechanism.

Abstract: A rear pressure bulkhead comprising a dome shaped structure, and a set of built-in extension components (“petals”) homogeneously distributed along the periphery of the dome-shaped structure. This results in the dome-shaped structure being secured to a frame of the aircraft, while the extension components are secured to longitudinal structures of the aircraft. An aircraft rear fuselage is provided including such a rear pressure bulkhead so that the available cabin space, i.e., pressurized space, is extended without enlarging the fuselage.

Abstract: A durable composite diamond electrode is disclosed which comprise at least a relatively thicker conductive UNCD (Ultrananocrystalline Diamond) layer, with low deposition cost, on a substrate underlying a relatively thinner conductive MCD (Microcrystalline Diamond) layer. The electrode exhibits long life and superior delamination resistance under extremely stressed electrochemical oxidation conditions. It is hypothesized that this improvement in electrode reliability is due to a combination of stress relief by the composite film with the slightly “softer” underlying UNCD “root” layer and the electrochemically durable overlying MCD “shield” layer, an effective disruption mechanism of the fracture propagation between the compositing layers, and thermal expansion coefficient match between the diamond layers and the substrate.

Abstract: A system of connecting a stiffener to the sidewall of a grain bin using a stud bolt having a first threaded end, a second threaded end and a feature positioned between the first end and a second end. A sealing member is positioned over the first end of the stud bolt, which in one case is a metallic washer with an affixed compressible sealing member. The first end of the stud bolt is inserted into a hole in the sidewall and an inner nut is placed over the first end inside the sidewall. As the inner nut is tightened, the feature is pulled toward the exterior surface of the grain bin thereby causing the sealing member to form a seal with the exterior surface of the grain bin. The second end of the stud bolt is inserted into a hole in the stiffener which is tightened onto the stud bolt.

Abstract: A method of controlling a discharge air reset in an heating, ventilation, air conditioning, and refrigeration (HVACR system includes determining, by a controller, a space temperature in a conditioned space, a setpoint temperature of the conditioned space, and an operating mode of a variable-air-volume (VAV) box for the conditioned space. The controller determines whether the operating mode of the VAV box matches an operating mode of an HVACR unit. A deviation from the setpoint temperature of the conditioned space for the VAV box for the conditioned is calculated in response to determining the VAV box is in a same mode as the HVACR unit. An average deviation from the setpoint temperature of the conditioned space is calculated. A discharge air setpoint temperature is determined based on the average deviation from the setpoint temperature of the conditioned space. The controller sets the discharge air setpoint temperature of the HVACR unit using the determined discharge air setpoint temperature.

Abstract: A method of controlling a discharge air reset in an heating, ventilation, air conditioning, and refrigeration (HVACR system includes determining, by a controller, a space temperature in a conditioned space, a setpoint temperature of the conditioned space, and an operating mode of a variable-air-volume (VAV) box for the conditioned space. The controller determines whether the operating mode of the VAV box matches an operating mode of an HVACR unit. A deviation from the setpoint temperature of the conditioned space for the VAV box for the conditioned is calculated in response to determining the VAV box is in a same mode as the HVACR unit. A statistical deviation from the setpoint temperature of the conditioned space is calculated. A discharge air setpoint temperature is determined based on the statistical deviation from the setpoint temperature of the conditioned space. The controller sets the discharge air setpoint temperature of the HVACR unit using the determined discharge air setpoint temperature.

Abstract: Strands of material may be intertwined using weaving techniques, knitting techniques, non-woven or entanglement techniques, or braiding techniques. Fabric that is formed from the strands of material may be used in forming a fabric-based item. The fabric based item may include electrical components. The strands may include conductive strands that form signal paths. The signal paths can carry electrical signals associated with operation of the electrical components. Each strand may have an elongated core and a coating. Strands may also include intermediate layers between the cores and coatings. The cores, intermediate layers, and coatings may be formed from polymer without conductive filler, polymer with conductive filler, and/or metal. A polymer core may be provided with recesses to help retain subsequently deposited layers such as a metal coating layer. The recesses may be grooves that extend along the longitudinal axis of the core.

Abstract: In an embodiment, a method for generating a search query for a graph database includes displaying a list of vertex properties on a user interface; receiving, via the user interface, a selection of one or more of the displayed vertex properties; forming a graph database query based on selection; and displaying a report containing a result of the query.

Abstract: Based on the three-dimensional structure of albumin, the inventors have designed variant polypeptides (muteins) which have one or more cysteine residues with a free thiol group (hereinafter referred to as “thio-albumin”). The variant polypeptide may be conjugated through the sulphur atom of the cysteine residue to a conjugation partner such as a bioactive compound.

Abstract: A chiller plant is disclosed. The chiller plant includes a chiller circuit including a chiller, a first process fluid circuit, and a first heat exchanger. The chiller is configured to provide a first process fluid at a first temperature. The chiller plant also includes an air handling circuit including a plurality of ice storage tanks and an air handling unit. The chiller plant further includes a terminal cooling circuit including a plurality of terminals, the terminal cooling circuit providing a second process fluid to the plurality of terminals at a second temperature that is different from the first temperature. The terminal cooling circuit is fluidly separate from, but thermally communicates with, the chiller circuit via the first heat exchanger.

Abstract: Strands of material may be intertwined using weaving techniques, knitting techniques, non-woven or entanglement techniques, or braiding techniques. Fabric that is formed from the strands of material may be used in forming a fabric-based item. The fabric based item may include electrical components. The strands may include conductive strands that form signal paths. The signal paths can carry electrical signals associated with operation of the electrical components. Each strand may have an elongated core and a coating. Strands may also include intermediate layers between the cores and coatings. The cores, intermediate layers, and coatings may be formed from polymer without conductive filler, polymer with conductive filler, and/or metal. A polymer core may be provided with recesses to help retain subsequently deposited layers such as a metal coating layer. The recesses may be grooves that extend along the longitudinal axis of the core.

Abstract: The disclosure discloses methods, devices, systems and kits for repairing, replacing and/or augmenting natural facet joint surfaces and/or facet capsules. An implantable facet joint device of one embodiment comprises a cephalad facet joint element and a caudal facet joint element. The cephalad facet joint element includes a member adapted to engage a first vertebra, and an artificial cephalad bearing member. The caudal facet joint element includes a connector adapted for fixation to a second vertebra at a fixation point and an artificial caudal bearing member adapted to engage the cephalad bearing member. The artificial caudal bearing member is adapted for a location lateral to the fixation point.