Patents by Inventor John A. MCCOY

John A. MCCOY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050250180
    Abstract: Novel polynucleotides and the proteins encoded thereby are disclosed.
    Type: Application
    Filed: October 22, 2003
    Publication date: November 10, 2005
    Inventors: Kenneth Jacobs, John McCoy, Edward LaVallie, Lisa Collins-Racie, Cheryl Evans, David Merberg, Maurice Treacy, Vikki Spaulding
  • Publication number: 20050231939
    Abstract: A flexible, translucent polymer purse that illuminates on its entire exterior surface for an appealing visual effect. The structure of the purse 10 is composed of a translucent polymer, to which is interchangeably attached a compact LED illumination unit 30 that shines light into a dimple 12, “pumping” light into the purse structure, causing it to glow from an internal refraction illumination. A purse that is manufactured with a process called “dip-molding,” which yields a product that is soft and compliant to touch, yet which retains a semi-rigid shape from its original manufacturing mold. A purse that uses the same refractory illumination method in its flexible polymer shoulder strap or carrying handle 40 as in its shell structure 10.
    Type: Application
    Filed: April 16, 2004
    Publication date: October 20, 2005
    Inventor: John McCoy
  • Publication number: 20050206751
    Abstract: An image processing system (10) obtains image sequences and assembles a presentation therefrom. The system has a camera (12) for capturing image sequences, a random-access electronic memory (16) for temporary storage of the image sequences, an input reader for accepting pre-programmed instructions from a first storage medium, a control panel with a display (18) for viewing image sequences (64) and presenting pre-programmed instructions to the operator and an operator interface for accepting responses to the pre-programmed instructions. A control logic processor (20) executes pre-programmed instructions and arranges the presentation from the captured image sequences stored in random-access electronic memory (16), according to operator responses. An output writer records the presentation onto a storage medium.
    Type: Application
    Filed: March 19, 2004
    Publication date: September 22, 2005
    Inventors: Joseph Manico, John Fredlund, Kenneth Parulski, Michael Telek, John McCoy
  • Publication number: 20050066603
    Abstract: Internally colored glass and glass-like blocks (10) and the method for making them. No means for coating the internal cavities (26) of clear glass and glass-like hollow blocks has been available. Color coating provides aesthetically pleasing structures. Internally colored glass and glass-like blocks may be used in building internal room dividers, providing colorful building designs and for providing color relief in heretofore otherwise drab structures.
    Type: Application
    Filed: July 31, 2003
    Publication date: March 31, 2005
    Inventors: John McCoy, Deborah Elliott
  • Publication number: 20050020528
    Abstract: This invention provides polynucleotides comprising sequences encoding amino-terminal-modified chemokines, the encoded amino-terminal-modified chemokines, and uses thereof.
    Type: Application
    Filed: August 23, 2004
    Publication date: January 27, 2005
    Inventors: Stephen Herrmann, Zhijian Lu, John McCoy, Stephen Swanberg, Bruce Walker, Otto Yang
  • Publication number: 20050003491
    Abstract: Novel polynucleotides and the proteins encoded thereby are disclosed.
    Type: Application
    Filed: August 9, 2004
    Publication date: January 6, 2005
    Applicant: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Kenneth Jacobs, John McCoy, Edward LaVallie, Lisa Collins-Racie, Cheryl Evans, David Merberg, Maurice Treacy, Michael Agostino, Robert Steininger, Vikki Spaulding, Gordon Wong, Hilary Clark, Kim Fechtel
  • Patent number: 6773530
    Abstract: A method for simultaneously building a plurality of tire carcasses includes the tire building steps of establishing a sequence of work stations, each at a predefined location along a working axis extending through the work stations. Disconnected tire building drums are advanced along the working axis extending through the work stations. The tire building drums are coupled to an intake server at each of the work stations for operating the tire building drums. One or more tire components are applied to the tire building drums at each of the work stations.
    Type: Grant
    Filed: September 21, 2001
    Date of Patent: August 10, 2004
    Assignee: The Goodyear Tire & Rubber Company
    Inventors: Ronald Bert Zeh, John Kolbjoern Roedseth, Michel Lemaire, Bryan John McCoy, Francesco Sorce, Fabrice Harry Martin
  • Publication number: 20030056877
    Abstract: A method for simultaneously building a plurality of tire carcasses includes the tire building steps of establishing a sequence of work stations, each at a predefined location along a working axis extending through the work stations. Disconnected tire building drums are advanced along the working axis extending through the work stations. The tire building drums are coupled to an intake server at each of the work stations for operating the tire building drums. One or more tire components are applied to the tire building drums at each of the work stations.
    Type: Application
    Filed: September 21, 2001
    Publication date: March 27, 2003
    Inventors: Ronald Bert Zeh, John Kolbjoern Roedseth, Michel Lemaire, Bryan John McCoy, Francesco Sorce, Fabrice Harry Martin
  • Publication number: 20030027139
    Abstract: Isolated polynucleotides which have been derived from a variety of human tissue sources, and which encode novel secreted proteins, are provided. Also provided are methods for producing proteins using these polynucleotides, and the proteins so produced.
    Type: Application
    Filed: March 29, 2001
    Publication date: February 6, 2003
    Inventors: Kenneth Jacobs, John McCoy, Edward R. LaVallie, Lisa Collins-Racie, Cheryl Evans, David Merberg, Maurice Treacy, Michael J. Agostino, Michael R. Bowman, Vikki Spaulding, Gordon G. Wong, Hilary F. Clark, Kim Fechtel, Steven H. Howes, Richard J. Resnick, Kalmalakar Gulukota, James R. Graham
  • Patent number: 6348191
    Abstract: IL-6 is produced via recombinant DNA techniques. The peptide is useful in the treatment of disorders characterized by deficiencies in hematopoietic cells and in combination with other hematopoietins in cancer therapies.
    Type: Grant
    Filed: June 17, 1991
    Date of Patent: February 19, 2002
    Assignee: Genetics Institute, Inc.
    Inventors: Steven C. Clark, Gordon G. Wong, Paul Schendel, John McCoy
  • Patent number: 6284237
    Abstract: IL-6 is produced via recombinant DNA techniques. The peptide is useful in the treatment of disorders characterized by deficiencies in hematopoietic cells and in combination with other hematopoietins in cancer therapies.
    Type: Grant
    Filed: April 6, 1994
    Date of Patent: September 4, 2001
    Inventors: Steven C. Clark, Gordon G. Wong, Paul Schendel, John McCoy
  • Patent number: 6143524
    Abstract: Provided is a fusion molecule comprising a DNA sequence encoding a thioredoxin-like protein fused to a DNA sequence encoding a second peptide or protein. The peptide or protein may be fused to the amino terminus of the thioredoxin-like molecule, the carboxyl terminus of the thioredoxin-like molecule, or within the thioredoxin-like molecule, for example at the active-site loop of the molecule. The fusion molecule may be modified to introduce one or more metal-binding/chelating amino-acid residues to aid in purification. Expression of this fusion molecule under the control of a regulatory sequence capable of directing its expression in a desired host cell, produces high levels of stable and soluble fusion protein. The fusion protein, located in the bacterial cytoplasm, may be selectively released from the cell by osmotic shock or freeze/thaw procedures. It may be optionally cleaved to liberate the soluble, correctly folded heterologous protein from the thioredoxin-like portion.
    Type: Grant
    Filed: March 4, 1997
    Date of Patent: November 7, 2000
    Assignee: Genetics Institute, Inc.
    Inventors: John McCoy, Elizabeth DiBlasio-Smith, Kathleen Grant, Edward R. LaVallie
  • Patent number: 6136536
    Abstract: Disclosed are methods, DNA sequences, vectors and cell lines useful for the rapid generation of stable mammalian cell lines expressing high levels of recombinant proteins.
    Type: Grant
    Filed: October 20, 1998
    Date of Patent: October 24, 2000
    Assignee: Genetics Institute, Inc.
    Inventors: Kathleen Tomkinson, Monique Davies, John McCoy
  • Patent number: 6014200
    Abstract: An electron beam lithography system having a beamlet shaping section that includes a first multi-aperture array having m rows and n columns of apertures having a first shape and a second multi-aperture array with m rows and n columns of apertures having a second shape. Electron beamlets formed by the first multi-aperture array are deflected by a deflector unit before passing through the second multi-aperture array. The superposition of the electron beamlets on the second multi-aperture produces electron beamlets having a selected shape. Deflection logic on an active beam aperture array blank selected electron beamlets. The deflection logic can be updated with the next logic pattern as the current logic pattern is being executed. The unblanked electron beamlets are directed onto a surface to be exposed.
    Type: Grant
    Filed: February 24, 1998
    Date of Patent: January 11, 2000
    Assignee: Nikon Corporation
    Inventors: Michael R. Sogard, John McCoy
  • Patent number: 5804416
    Abstract: DNA molecules encoding mutant forms of bone morphogenetic proteins (BMP) are disclosed. The mutant forms of BMP can be produced bacterially and refolded to produce biologically active homodimers or heterodimers of BMP. A method of making such mutant BMPs is also disclosed.
    Type: Grant
    Filed: October 31, 1996
    Date of Patent: September 8, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: Neil M. Wolfman, John McCoy
  • Patent number: 5756308
    Abstract: DNA molecules encoding mutant forms of bone morphogenetic proteins (BMP) are disclosed. The mutant forms of BMP can be produced bacterially and refolded to produce biologically active homodimers or heterodimers of BMP. A method of making such mutant BMPs is also disclosed.
    Type: Grant
    Filed: December 21, 1994
    Date of Patent: May 26, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: Neil M. Wolfman, John McCoy
  • Patent number: 5679205
    Abstract: A tire liner applier and method wherein a die and anvil shape the ends of the liner at a predetermined section which is transferred to a position adjacent the tire building drum where the section is stretched and the trailing end stitched against the drum. The leading end is clamped and applied to the drum where the next tire is built. The leading end and trailing end are tapered so that they slope away from the drum and provide a smooth transition where the ends contact the drum and outer layer of liner material. A butt splice may also be provided.
    Type: Grant
    Filed: June 26, 1995
    Date of Patent: October 21, 1997
    Assignee: The Goodyear Tire & Rubber Company
    Inventors: Patrick David Marks, Bryan John McCoy
  • Patent number: 5646016
    Abstract: Provided is a fusion molecule comprising a DNA sequence encoding a thioredoxin-like protein fused to a DNA sequence encoding a second peptide or protein. The peptide or protein may be fused to the amino terminus of the thioredoxin-like molecule, the carboxyl terminus of the thioredoxin-like molecule, or within the thioredoxin-like molecule, for example at the active-site loop of said molecule. The fusion molecule may be modified to introduce one or more metal-binding/chelating amino-acid residues to aid in purification. Expression of this fusion molecule under the control of a regulatory sequence capable of directing its expression in a desired host cell, produces high levels of stable and soluble fusion protein. The fusion protein, located in the bacterial cytoplasm, may be selectively released from the cell by osmotic shock or freeze/thaw procedures. It may be optionally cleaved to liberate the soluble, correctly folded heterologous protein from the thioredoxin-like portion.
    Type: Grant
    Filed: December 10, 1993
    Date of Patent: July 8, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: John McCoy, Elizabeth DiBlasio-Smith, Kathleen Grant, Edward R. LaVallie
  • Patent number: 5399677
    Abstract: DNA molecules encoding mutant forms of bone morphogenetic proteins (BMP) are disclosed, The mutant forms of BMP can be produced bacterially and refolded to produce biologically active homodimers or heterodimers of BMP. A method of making such mutant BMPs is also disclosed.
    Type: Grant
    Filed: December 7, 1993
    Date of Patent: March 21, 1995
    Assignee: Genetics Institute, Inc.
    Inventors: Neil M. Wolfman, John McCoy
  • Patent number: 5292646
    Abstract: This invention provides a fusion molecule comprising a DNA sequence encoding a thioredoxin-like protein fused to the DNA sequence encoding a selected heterologous peptide or protein. The peptide or protein may be fused to the amino terminus of the thioredoxin-like molecule, the carboxyl terminus of the thioredoxin-like molecule, or within the thioredoxin-like molecule, for example at the active-site loop of said molecule. Expression of this fusion molecule under the control of a regulatory sequence capable of directing its expression in a desired host cell, produces high levels of stable and soluble fusion protein. The fusion protein, located in the bacterial cytoplasm, may be selectively released from the cell by osmotic shock or freeze/thaw procedures. It may be optionally cleaved to liberate the soluble, correctly folded heterologous protein from the thioredoxin-like portion.
    Type: Grant
    Filed: July 28, 1992
    Date of Patent: March 8, 1994
    Assignee: Genetics Institute, Inc.
    Inventors: John McCoy, Edward R. LaVallie