Abstract: A method for optimizing alignment performance in a fleet of exposure systems involves characterizing each exposure system in a fleet of exposure systems to generate a set of distinctive distortion profiles associated with each exposure system. The set of distinctive distortion profiles are stored in a database. A wafer having reference pattern formed thereon is provided for further pattern fabrication and an exposure system is selected from the fleet to fabricate a next layer on the wafer. Linear and higher order parameters of the selected exposure system are adjusted using the distinctive distortion profiles to model the distortion of the reference pattern. Once the exposure system is adjusted, it is used to form a lithographic pattern on the wafer.

Abstract: An improved Quad Flat No-Lead package is described. The package is formed by encapsulating a die mounted on a leadframe with a moulding compound using a mould chase. The mould chase comprises a number of internal projections which form openings in the mould compound to expose regions of the leadframe. These exposed regions of the leadframe may then be used for soldering the package to a substrate. The arrangement of the openings may be designed such that each aperture is the same shape and size and/or that the apertures are arranged in multiple rows on the underside of the package.

Abstract: The inventive blanket is an inflatable underbody convective thermal blanket whereon the head and the upper body of a patient may lie. The blanket is in the shape of a cross with a truncated lower vertical portion and an upper head portion onto which the head of the patient lies. The blanket has two horizontal arm portions that extend from the main body portion of the blanket and onto which the arms of the patient may be positioned. At each of the arm portions there is a flap that may be used to cover the arm of the patient. An inlet port is provided in an upper corner at the head portion of the blanket. The heated air input to the blanket is directed by a plurality of sealed strips to flow in respective desired directions around the arm portions and the lower truncated body portion of the blanket. Sets of apertures are provided along an inner sealed periphery that defines a T-shaped uninflated area onto which the torso of the patient lies.

Abstract: Compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6, X, R7, and R8 are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.

Abstract: The invention relates to lipopeptide building blocks consisting of a peptide chain comprising a coiled-coil domain, linked covalently to a lipid moiety comprising long alkyl or alkenyl chains, and optionally linked to an antigen; and to helical lipopeptide bundles and synthetic virus-like particles formed by aggregation. The nanometer size and shape of these bundles and particles, their stability under aqueous physiological conditions, their chemical composition, the possibility to incorporate B- and T-cell epitopes, and their production by chemical synthesis, make them highly suitable as vaccine delivery vehicles.

Abstract: On the fly tuning of parameters used in an interface between a memory (e.g. high speed memory such as DRAM) and a processor requesting access to the memory. In an operational mode, a memory controller couples the processor to the memory. The memory controller can also inhibit the operational mode to initiate a training mode. In the training mode, the memory controller tunes one or more parameters (voltage references, timing skews, etc.) used in an upcoming operational mode. The access to the memory may be from an isochronous process running on a graphics processor. The memory controller determines whether the isochronous process may be inhibited before entering the training mode. If memory buffers for the isochronous process are such that the training mode will not impact the isochronous process, then the memory controller can enter the training mode to tune the interface parameters without negatively impacting the process.

Abstract: The present invention relates to methods for synthesizing conformationally constrained peptides and cyclic peptidomimetics obtainable by these methods which are conformationally constrained due an internal cross-link. This cross-link is formed between the side chain of an amino acid residue or analog and a (2S, 4S)4-functionalized proline residue. The invention further relates to the use of (2S, 4S)-4-functionalized proline residues as building units in the synthesis of such peptidomimetics and to the use thereof as antigens, alone or in combination with suitable immunopotentiating delivery systems, for example immunopotentiating reconstituted influenza virosomes to elicit an immune response in a mammal. Moreover, the invention also relates to pharmaceutical compositions containing the same.

Abstract: Compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6, and R7 are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.

Abstract: An improved meter and its operation is described. The meter can be a part of a larger automated meter reading process that allows for remote reading of the meter though power line communication. Using a microcomputer core, the meter processes incoming analog data and can calculate several relevant data values need by utility providers. The meter can also be used to monitor and detect tampering dry connect/voltage free devices, such as gas and water meters, connected to the meter.

Abstract: A multi-flash photography system provides a dynamically-configurable lighting environment for a single exposure that is created and shaped through the sequentially firing of various light sources with different lighting characteristics controlled in accordance with both a programmed template specifying the flash type, position, firing order, and output intensity, as well as optical processing requirements such as filtering, polarizing, etc., and a shared photometric detector located sufficiently close to the subject being photographed to ensure that the light seen by the detector is substantially the same as the light received at the subject.

Abstract: An improved meter and its operation is described. The meter can be a part of a larger automated meter reading process that allows for remote reading of the meter though power line communication. Using a microcomputer core, the meter processes incoming analog data and can calculate several relevant data values need by utility providers. The meter can also be used to monitor and detect tampering dry connect/voltage free devices, such as gas and water meters, connected to the meter.

Abstract: Compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6, and X are as defined herein for Formula (IA) and Formula (IB), or a tautomer, prodrug, solvate, or salt thereof, pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.

Abstract: The present invention relates to methods for synthesizing conformationally constrained peptides and cyclic peptidomimetics obtainable by these methods which are conformationally constrained due an internal cross-link. This cross-link is formed between the side chain of an amino acid residue or analog and a (2S, 4S)4-functionalized proline residue. The invention further relates to the use of (2S, 4S)-4-functionalized proline residues as building units in the synthesis of such peptidomimetics and to the use thereof as antigens, alone or in combination with suitable immunopotentiating delivery systems, for example immunopotentiating reconstituted influenza virosomes to elicit an immune response in a mammal. Moreover, the invention also relates to pharmaceutical compositions containing the same.

Abstract: Compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6 and X are as defined herein for Formula (IA) and Formula (IB), or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.

Abstract: Paper pulp is added to a stain solution. The stain solution and pulp fibers are mixed to form a slurry. Samples are removed from the slurry and are admixed with dilution water and a bleach. Then, the fibers are moved into a flow cell where they are subjected to a light source adapted to stimulate fluorescence from the stained pulp fiber. Before the fiber slurry enters the flow cell it is mixed with a dilution water of bleach to reduce background fluorescence. The fluorescent light is collimated and directed through a dichroic filter onto a fluorescence splitting dichroic filter.

Abstract: An assembly comprises a part for example a part of an item of cookware, bakeware, domestic appliance or the like which is subjected to a wear means in use such that the wear means may abrade the outer surface of the part. The part is provided with an outer surface which comprises a polyaryletherketone polymer, especially polyetheretherketone, and a fluoropolymer. Such a combination is found to exhibit superior wear properties over other known materials.

Abstract: A method and apparatus for process control in a lithographic process are described. Metrology may be performed on a substrate either before or after performing a lithographic patterning process on the substrate. One or more correctables to the lithographic patterning process may be generated based on the metrology. The lithographic patterning process performed on the substrate (or a subsequent substrate) may be adjusted with the correctables.

Abstract: Various methods and systems for creating or performing a dynamic sampling scheme for a process during which measurements are performed on wafers are provided. One method for creating a dynamic sampling scheme for a process during which measurements are performed on wafers includes performing the measurements on all of the wafers in at least one lot at all measurement spots on the wafers. The method also includes determining an optimal sampling scheme, an enhanced sampling scheme, a reduced sampling scheme, and thresholds for the dynamic sampling scheme for the process based on results of the measurements. The thresholds correspond to values of the measurements at which the optimal sampling scheme, the enhanced sampling scheme, and the reduced sampling scheme are to be used for the process.

Abstract: This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.

Abstract: Garment supporting devices and garment hangers are disclosed. One garment supporting device for attaching to a garment hanger comprises a shoulder receiving section operable to conform to a shoulder region of a garment when hung on the garment hanger. By being attachable to a conventional garment hanger, the garment supporting device effectively alters the dimensions of the hanger to accommodate the dimensions of the garment to be supported, especially its shoulder regions. Adapting the shoulder receiving section to conform to the shoulder region of a garment enables the same device to be applied to a conventional hanger in order to support garments having a range of differing sizes. Conforming to the shoulder region increases support in this region and reduces the likelihood of creating deformations therein.