Abstract: A system for obtaining optical coherence tomography of the optical system of a person, comprising: an eyepiece customized for alignment and positioning to contact a person's eye socket and having a lens pocket for receiving a refractive lens customized for the person's eye refraction characteristics; a condensing system for receiving light from the eyepiece; a scanning module optically connected to the condensing system and having a mirror tiltable in two directions for obtaining optical scanning data from the person's optical system; and a spectrometer and camera module optically connected to the scanning module for obtaining and storing the optical scanning data, wherein the eyepiece, condensing system and scanning module are arranged to provide an optical path for delivering a light beam to the person's eye, and receive reflected light to be directed to the scanning module.

Abstract: The invention provides a versatile sensing platform for sensing and analysis of biofluids, particularly well-suited for sensing and analysis of sweat. Systems of the invention allows for sensitive and selective detection of a range of analytes in sweat including metabolites, electrolytes and biomarkers. Systems of the invention provide a noninvasive and accurate means for quantitative characterization of important sweat characteristics including sweat volume, sweat loss and sweat rate. Systems of the invention are compatible with materials and device geometries for important class of conformal tissue mounted electronic devices, including epidermal electronic devices.

Abstract: An electronic system for multimodal diagnostic measurements and therapeutic interventions includes a plurality of element network layers vertically stacked one with another on a flexible substrate, each element network layer being bi-axially stretchable and comprising a plurality of elements configured in an addressable, interconnected array formed in a multilayered structure and operably performing a distinct function. The electronic system is a multimodal, multiplexed soft electronic system in a multilayered configuration that supports capabilities ranging from high-density spatiotemporal mapping of temperature, pressure and electrophysiological parameters, to options in programmable high-density actuation of thermal inputs and/or electrical stimulation, drug elution, radio frequency ablation, and/or irreversible electroporation ablation.

Abstract: Provided are systems and methods for wireless, LCR-based, passive sensor systems for catheter or other implantable deployment using collapsible electromechanics. Each sensor system includes a deformable coil and a capacitive pressure sensor, collectively forming a LCR circuit having a self-resonant frequency. Multiple sensor systems may be implanted in a collapsible artificial valve to non-invasively detect the status of the collapsible artificial valve. Specifically, when the collapsible artificial valve is implanted in a mammal subject, antennas may be disposed on the skin of the mammal subject to wirelessly measure the self-resonant frequencies of the LCR circuits of the sensor systems. Thus, the blood pressure of the mammal subject may be calculated based on the self-resonant frequencies measured by the antenna, and the status of the collapsible artificial valve may be determined based on the blood pressure.

Abstract: This invention discloses a sensor for measuring parameters of sweat from a skin, comprising a flexible structure comprising a fluid passage having inlet and outlet, the flexible structure being detachably attached to the skin and configured such that sweat enters the inlet as the sweat releases from the skin and flows through the fluid passage into the outlet; a thermal actuator disposed on the flexible structure over the fluid passage and configured to operably provide heat to flow of the sweat through the fluid passage; a first thermistor disposed on the flexible structure over the fluid passage between the inlet and the thermal actuator and configured to operably measure a first temperature of the sweat thereon; and a second thermistor disposed on the flexible structure over the fluid passage between the thermal actuator and the outlet and configured to operably measure a second temperature of the sweat thereon.

Abstract: A method of measuring a gas concentration is described. The method comprises illuminating, with a light source, a volume of space that includes a gas and measuring, with a detector, a first illumination level of the volume of space. The method further comprises determining, via a processor, a gas concentration in the volume of space based on the measured first illumination level, where the volume of space is configured to be in fluid communication with a gas recirculation flow path including a catalyst, the catalyst configured to substantially remove the gas from the volume of space.

Abstract: An apparatus for artificial intelligence (AI) bathymetry is disclosed. The apparatus includes a sonic unit attached to a boat, the sonic unit configured to generate a plurality of metric data as a function of a plurality of ultrasonic pulses and a plurality of return pulses. An image processing module is configured to generate a bathymetric image as a function of the plurality of metric data, identify, as a function of the bathymetric image, an underwater landmark, and register the bathymetric image to a map location as a function of the underwater landmark. A communication module is configured to transmit the registered bathymetric image to at least a computing device. An autonomous navigation module is configured to determine a heading for the boat as a function of a path datum and command boat control to navigate the boat as a function of the heading.

Abstract: The invention relates to a hydration sensor comprising a sensing module operably disposed on a target area of interest of skin of a living subject for detecting data associated with thermal properties of the skin; and a wireless platform coupled with the sensing module for wireless data transmission between the sensing module and an external device. The sensing module comprises a thermal actuator for operably heating the target area of interest thereof; and a sensing circuit for simultaneously detecting a transient temperature change thereof to determine thermal properties of the skin.

Abstract: In some implementations, a system enables users to create dynamically configurable applications that can be dynamically configured and adjusted. An application that runs on the server system in a first configuration is configured using a first configuration template. Data indicating (i) that the application is being accessed on a computing device in the first configuration, and (ii) a request to adjust the first configuration of the application is received. Operations are then performed while the application is being accessed on the computing device in the first configuration. A second configuration template that specifies a second configuration of the application corresponding to the request included in the received data is generated. The application is adjusted using the second configuration template to run in the second configuration. An instruction is provided to the computing device to enable the computing device to access the application running in the second configuration.

Abstract: This disclosure relates to the field of mass spectrometry analysis. In some embodiments, the disclosure relates to compositions and methods for detecting and quantifying proteins in the AKT-mTOR pathway by immunoprecipitation enrichment followed by mass spectrometry analysis.

Abstract: An electronic system for monitoring a physical parameter includes an ADM comprising an accumulation mode sensor for measuring the physical parameter by generating electrical energy associated with the physical parameter in response to a surrounding condition, and an energy storing device coupled to the accumulation mode sensor for accumulatively storing the generated electrical energy; a power source; and an SoC coupling with the ADM and the power source, configured such that the stored electrical energy is monitored, and when the stored electrical energy is equal to or greater than a pre-defined threshold, a wake-up event is generated to trigger the SoC to operates in a run mode in which the physical parameter is wirelessly transmitted to a receiver and the stored electrical energy in the energy storing device is discharged, and then the SoC returns to a sleep mode in which a minimal power is consumed.

Abstract: A system, apparatus, and method include a pump to deliver vapor including airborne contaminants including organic compounds including a target analyte; a collector to transfer the airborne contaminants by autonomous liquid extraction into a mobile organic liquid phase; a micro-fluidic chamber including immobilized biorecognition elements that bind to analytes delivered from the mobile organic liquid phase; a mechanism to introduce the mobile organic liquid phase to a buffer containing a plurality of substrates causing a series of biochemical reactions that create a change corresponding to a concentration of the target analyte; and a detector to perform real-time analysis that correlates to a concentration of the organic compounds to determine a presence of the target analyte.

Abstract: This disclosure is directed to methods, computer program products, and systems for calibrating one or more remote sensing devices in an environment. The disclosed technology relates to a calibration device configured to determine measurement data within an environment. The calibration device may transmit the measurement values, or other calibration data items, to a remote sensing device via a wireless link while the remote sensing device stays with a structure in which the remote sensing device is commissioned to operate. In response to receiving the calibration data items, the remote sensing device may adjust one or more settings of the remote sensing device in order to satisfy a calibration threshold.

Abstract: An implantable bioresorbable radio frequency (RF) coil for high-resolution and high-specificity post-surgical evaluating or monitoring with magnetic resonance imaging (MRI) is disclosed. The coil includes a bioresorbable conductor configured to be resorbed within a patient while the coil is implanted in the patient. In one embodiment, the target application of this coil is the evaluation or monitoring (via MRI) of peripheral nerve regeneration following surgical repair.

Abstract: Provided are methods of making a liquid and liquid vapor-proof material, and relates long-term implantable electronic devices. The method comprisies providing a first substrate having a first-side encapsulating layer supported by at least a portion of the first substrate; providing a material onto the first-side encapsulating layer; providing a second substrate having a second-side encapsulating layer supported by at least a portion of the second substrate; covering an exposed surface of the material provided onto the first-side encapsulation layer with the second-side encapsulating layer; wherein said encapsulating layers are substantially defect free so that liquid or liquid vapor is prevented from passing through each of the encapsulating layers; thereby making the liquid or liquid vapor-proof material.

Abstract: Apparatuses, systems, and techniques to generate a trusted execution environment including multiple accelerators. In at least one embodiment, a parallel processing unit (PPU), such as a graphics processing unit (GPU), operates in a secure execution mode including a protect memory region. Furthermore, in an embodiment, a cryptographic key is utilzed to protect data during transmission between the accelerators.

Abstract: A method for block loading an electrical grid with a combined cycle power plant (CCPP) includes operating a gas turbine system of the CCPP in an islanding mode with a steam turbine system of the CCPP off line with turning gear rotating only; loading the steam turbine system accordingly to temperature matching conditions of the steam turbine system, the loading of the steam turbine system includes controlling gas turbine exhaust fed to the steam turbine system and the gas turbine exhaust temperature heats the steam turbine system and to meet temperature matching conditions of the steam turbine system; wherein controlling gas turbine exhaust includes controlling fuel flow and air flow to the gas turbine system; and operating at least one of the gas turbine system and steam turbine system to block load the electrical grid from a load on at least one of gas turbine system and steam turbine system.

Abstract: Apparatuses, systems, and techniques to generate a trusted execution environment including multiple accelerators. In at least one embodiment, a parallel processing unit (PPU), such as a graphics processing unit (GPU), operates in a secure execution mode including a protect memory region. Furthermore, in an embodiment, a cryptographic key is utilized to protect data during transmission between the accelerators.

Abstract: Provided are conformable light delivery devices for increasing light penetration depth and related methods. The device comprises a tissue penetrating member having a distal end and a proximal end, the tissue penetrating member configured to penetrate the tissue of the patient to be inserted into the tissue, wherein the tissue penetrating member is at least partially optically transparent along a surface of the tissue penetrating member positioned between the distal end of the tissue penetrating member and the proximal end of the tissue penetrating member to provide optical transmission of at least a portion of the light through the surface of the tissue penetrating member, thereby allowing at least the portion of the light to be delivered into the tissue of the patient when the tissue penetrating member is inserted into the tissue; and a substrate that supports the tissue penetrating member.

Abstract: This document presents a system and method for presenting vetted and verified Supplier information to Buyers. The Know Your Suppler (TYS) Application collects previously vetted and verified Supplier information and commits the collected information, verification authorities, verification details, and transaction information to a shared distributed ledger implemented as a privately permissioned blockchain. Buyers who want to onboard a newly identified Supplier, or update Supplier information with more recently verified information records, may subscribe to the TYS Application and purchase available vetted and verified Supplier information to optimize the onhoarding or updating process for Suppliers from whom the Buyer wants to purchase goods or services.