Abstract: A home cost analysis server for executing a customized home search may include a processor programmed to define a user budget constraint, receive a list of available homes, and determine an initial monthly cost for each home. The processor may also identify one or more additional home costs based on historical insurance claim data. The processor may also display available homes that satisfy the user budget constraint.

Abstract: Disclosed herein are compositions and methods for treating diseases characterized by expanded microsatellite repeats by impeding or inhibiting transcription of expanded microsatellite repeats.

Abstract: Super water absorbents (SWA) based from cassava starch and acrylic acid (AAc) were prepared by gamma irradiation for agricultural applications. The influence of synthesis parameters on the gel properties of SWA and its effect on the soil water retention were investigated. Gel fraction of the different SWAs ranged from 40 to 98% and degree of swelling reached up to about 483 g water/g dry gel and SWAs exhibited gel strength up to 1000 kPa. The SWA with superior gel and soil water retention properties was found to be the formulation of 20% AAc, 30% DN, 7.5% starch and radiation dose of 20 kGy. This SWA effectively retained water in clay-rich soil while its water absorption in sandy loam increased with time. It has a biodegradation rate of 39% in 132 days. Preliminary pot experiments showed that the developed SWA can enhance the growth of lettuce.

Abstract: Provided are methods, prokaryotic host cells, expression vectors, and kits for the production of a tryptophan, a tryptamine, or an intermediate or a side product thereof, or a derivative thereof. In some embodiments, the tryptophan, tryptamine, intermediate or side product is a non-naturally occurring derivative. In some embodiments, the tryptamine is a psilocybin derivative. In certain embodiments, the prokaryotic host cell is selected from the group consisting of Escherichia coli, Corynebacterium glutamicum, Vibrio natriegens, Bacillus subtilis, Bacillus megaterium, Escherichia coli Nissle 1917, Clostridium acetobutlyicum, Streptomyces coelicolor, Lactococcus lactis, Pseudomonas putida, Streptomyces clavuligerus, and Streptomyces venezuelae.

Abstract: A covert sports communication system has a transmitter configured to wirelessly transmit coded audio track selection signals. The system includes a receiver that may be worn within headgear. The receiver includes stored audio tracks and is configured to receive coded audio track selection signals from the transmitter, decode the audio track selection signals, and play at least one stored audio track in accordance with the decoded audio track selection signals. The audio tracks may include audio instructions to a participant of a sporting event.

Abstract: A method for stabilizing a motion of a rotor blade of a rotor comprising the steps: read into a controller, a measurement from a sensor responsive to said rotor blade; determine an out-of-compliance motion of the rotor blade; and output a first control signal to an actuator affecting the rotor blade such that a vibration mode of said rotor blade is dampened. The damping may be achieved by changing the drag, lift or torsion of the rotor blade. The out-of-compliance motion may be a lead, lag, upward motion, downward motion or twist of the rotor blade away from a nominal value.

Abstract: Performance parameters of a vehicle can be measured by an on-board performance parameter measuring device. The performance parameters can be measured while the vehicle is being used. The measured performance parameters of the vehicle can be transmitted to a computing device. The computing device can be configured to generate a user cost that reflects a cost for insuring the vehicle based on the measured performance parameters of the vehicle. A graphical user interface can be generated by the computing device for presentation to a user via a display device, that graphical user interface can include the user cost. An alternative transportation route for the journey and an alternative transportation cost for the journey can be determined and presented to the user through the graphical user interface.

Abstract: A wearable article includes a front and back elastic belts, a crotch region, a waist opening, and leg openings. Each elastic belt is a laminate having an inner sheet, an outer sheet, and an elastic member. Elastic adhesive bonding continuously bonds the elastic member for at least about 10 mm in the direction of stretch adjacent the side edges of the belts. A discrete patterned adhesive bonding is applied to at least one of the inner and outer sheets to intermittently bond the inner and outer sheets. The discrete patterned adhesive bonding extends substantially along the transverse direction between the elastic adhesive bonding, and substantially along the longitudinal direction between the distal and proximal edges of the elastic belts. The same adhesive agent provides the elastic adhesive and discrete patterned adhesive bonding. Heat bonds form side seams, and the remainder of the laminate is free of heat bonds.

Abstract: Examples described herein relate to a network interface device comprising: an interface to a port; and circuitry to: perform parallel evaluation of multiple rules for a packet; drop the packet based at least in part on an indication by the parallel evaluation that communication with a target is not permitted; and permit communication of the packet based at least in part on a second indication by the parallel evaluation that communication with the target is permitted. In some examples, the parallel evaluation of multiple rules is to evaluate one or more of: a permitted sender Internet Protocol (IP) address range, a permitted destination IP address range, a permitted packet protocol, or a permitted egress port range.

Abstract: The present disclosure provides isolated anti-IL1RAP antibodies comprising the complementarity determining regions (CDRs) amino acid sequences, as disclosed herein. The disclosure further provides specific variable heavy chain and variable light chain amino acid sequences of these isolated anti-IL1RAP antibodies. The anti-IL1RAP antibodies target downstream IL1RAP activity appear useful for treating diseases such as cancer.

Abstract: A current transformer includes a first housing including a first handle portion and a first distal portion, a second housing including a second handle portion and a second distal portion, a first core mounted in in the first distal portion, a second core mounted in the second distal portion, and a lock attached to the second handle portion at a pivot point, wherein the first housing is rotationally coupled to the second housing about a fulcrum point and the lock is rotatable about the pivot point into a closed position wherein the lock engages the first handle portion and prevents the first handle portion and the second handle portion from rotating towards each other.

Abstract: A surgical footswitch for controlling a surgical instrument. The surgical footswitch includes a base. A treadle is rotatably coupled to the base to operate the surgical instrument. A foot guard is also rotatably coupled to the base. A blocking portion of the foot guard is configured to prevent physical access to the treadle in a lateral direction in a first position and permit access to the treadle in a lateral direction in a second position. A floor engagement portion of the foot guard engages a floor surface when the blocking portion is in the first position. The floor engagement portion is spaced from the floor surface when the blocking portion is in the second position. The floor engagement portion permits physical access to the treadle in a longitudinal direction when the blocking portion is in both the first position and the second position.

Abstract: Provided herein are polynucleotides and CRISPR effector proteins configured to be covalently bound together in a CRISPR complex. The polynucleotides can be further modified to modulate the activity of the CRISPR complex. Modification of the polynucleotide and CRISPR effector protein can be used to improve the efficacy of target binding and/or cleavage.

Abstract: Devices and methods are provided that utilize two adjacent nanopore readers for sequencing of a polymer or a portion thereof.

Abstract: A catheter sheath device may include an elongate member and a moveable member. The elongate member may include a first lumen, and the moveable member may include a second lumen. The moveable member may be physically coupled to a portion of the elongate member to permit relative movement therebetween. A first relative movement between the moveable member and a portion of the elongate member may cause the second lumen to be positioned at a first location that permits delivery of at least a portion of a catheter into the second lumen but not into the first lumen from the second lumen. A second relative movement between the moveable member and the portion of the elongate member may cause the second lumen to be positioned at a second location that permits delivery of the at least the portion of the catheter through both the second lumen and the first lumen.

Abstract: A spinal implant includes a first member configured to penetrate tissue and a second member. The second member has an abutment engageable with a surgical instrument and at least one peripheral capture element engageable with a moveable arm of the surgical instrument. Systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: Disclosed is a wearable article comprising front and back elastic belt regions and a crotch region between the front and back elastic belt regions; the front and back elastic belt regions each comprising a laminate, an elastic bonding continuously bonding an elastic member in the direction of stretch, and a vertical bonding applied to at least one of inner and outer sheets to intermittently bond the elastic member to at least one of the inner and outer sheets, the vertical bonding having a transverse dimension VG2 and spaced apart from each other with a transverse pitch VG1, wherein the outer sheet comprises a repeating pattern of apertures, the repeating pattern of apertures spaced apart from each other with a longitudinal pitch DF2, and spaced apart from each other with a transverse pitch DF1, wherein VG1 is greater than DF1, and wherein the repeating pattern of apertures have a Longitudinal Orientation.

Abstract: The present disclosure provides systems and techniques for an electromechanical sear that is implementable in a gun. The gun may include a fire control manager, and the fire control manager may identify a trigger break based on a trigger sensor, transmit, based on the trigger break, a first signal to a first actuator located in a displacement path of a sear, so as to cause the first actuator to be displaced in a first direction, and transmit, based on the trigger break, a second signal to a second actuator located in the displacement path of the sear, so as to cause the second actuator to be displaced in a second direction. The transmitting the first signal to the first actuator and the transmitting the second signal to the second actuator may cause displacement of the sear and firing of the gun.

Abstract: A sensor assembly for a prosthetic or orthotic device (POD) may include a housing and a support. The housing may be attached with the POD. The support may be moveably connected with the housing such that the support may move relative to the housing. The support may form an enclosure with the housing. Within the enclosure, the sensor assembly may include one or more sensors and a circuit board. The one or more sensors may include one or more of an inertial measurement unit, an electromyography sensor, or a distance sensor such as a magnetic sensor and a magnet. The circuit board may be attached with the support and in electrical communication with the plurality of sensors. Movement of the support may cause the sensors to move which may be detected for control of the POD. The sensor assembly may be attached to an arm or other prosthetic socket for detection of natural limb movements.

Abstract: The following relates generally to determining and/or displaying home scores. In some embodiments, one or more processors: (1) identify an upgrade and/or service to a home; (2) determine a home score improvement that the upgrade and/or service would make for an overall home score, a home safety subscore, a fire protection subscore, a sustainability subscore, and/or a home automation subscore; and/or (3) display the home score improvement along with an indication of the upgrade and/or service on a display.