Abstract: Disclosed are sustained release drug particles suitable for forming sustained release oral pharmaceutical compositions. The sustained release drug particles comprise a drug-ion exchange resin complex and a water-permeable, diffusion barrier surrounding at least a portion of the drug-ion exchange resin complex. The diffusion barrier comprises a film-forming polymer and is free or contains no substantial traces of organic solvent. Also disclosed are oral pharmaceutical compositions, for example, oral suspensions, comprising the sustained release drug particles, a method for the controlled administration of a drug to a patient, and a method for manufacturing the sustained release drug particles. The method of manufacturing involves the use of an aqueous coating composition comprising a water-permeable film-forming polymer such as ethylcellulose.

Abstract: A motorized vehicle includes a vehicle body having a rigid frame in a shape of a tractor; and a plurality of audio and visual devices disposed on the vehicle body, including a camera. The vehicle can be remote-controlled, and the vehicle body may be armored and may include a weapon system. The camera may be one of a motion, thermal, digital, and near infrared camera, and may be retractable into a housing. In another embodiment, the motorized vehicle, which may be remote-controlled, includes a vehicle body having a rigid frame in a rectangular shape with sloped sides; at least one storage unit accessed by doors, disposed within the vehicle body; and a camera disposed on the vehicle body.

Abstract: A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.

Abstract: A spring loaded device assembly includes a spring loaded device for use with hydraulic systems, the spring loaded device including: a spring mechanism disposed in an outer tubular member; an inner tubular member movably disposed in one end of the outer tubular member; an adjustment rod movably disposed in the inner tubular member; a clevis attached to a distal end of the adjustment rod for attachment to a hydraulic system; and a rigid mounting member having two ends, a first end being attached to another end of the outer tubular member, and a second end being attached to the hydraulic system to prevent swivel of the spring loaded device.

Abstract: A scan tool is provided for automated remote data collection. The scan tool is provided to and executed at the customer site. The scan tool collects debug data, including, for example, configuration information, and sends the debug data to a customer service site. A comparison utility at the customer service site compares the debug data to a code level database, which holds valid code levels and their relationships. Historical and current data may be searched. Code levels may be updated and maintained in the code level database. The comparison utility presents mismatches, which may then be communicated back to the customer. If there are no mismatches, engineers may manually check the debug data for errors, which may also be communicated to the customer.

Abstract: The present invention provides compositions and methods for the treatment of infection in a subject. More particularly, the invention provides a therapy for the treatment or prevention of mammary infections, such as bovine mastitis, comprising the topical administration to a subject of an anti-microbial agent and a phospholipid-containing skin conditioner.

Abstract: A floor defining structure reliant upon a confinement periphery around a bed of compacted free draining material on which is positioned one or more floor panel support pads. The floor itself is supported directly or indirectly by both the confinement periphery and the pads. The pads are of such a kind that will not provide any wicking upwardly of any moisture from the bed material and are heat insulating in nature. Preferably each pad comprises an insulating material above a damp coarse layer and below a structural layer to which and/or into which the floor defining panel or panels can be fixed by adhesive, nailing and/or screwing.

Abstract: A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.

Abstract: A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.

Abstract: A pipe support is provided that includes a frame capable of being placed around an existing pipe and a plurality of support members within the frame. The frame is a hollow cylinder that includes two connectable halves divided along the diameter of the hollow cylinder. The pipe support includes two bearing rings connected to the frame for supporting each of the plurality of members at a minimum of two contact points. Each of the two bearing rings include bearing points for each support member arranged in a cylindrical pattern concentric with the hollow cylinder frame. The pipe support includes means for rotating each of the support members at a first contact point with respect to a second contact point so that the support members engage a pipe placed within the pipe support. The support members are rods that provide vibration isolation to a pipe placed within the pipe support.

Abstract: A hair treatment composition comprises particles having a first non-aqueous phase and, retained within said first non-aqueous phase, a second hydrophilic phase which is an aqueous solution, dispersion, emulsion or a solid or liquid having a log P value less than 1, said second phase comprising a hair benefit agent, wherein said first non-aqueous phase has a melting point of from 30° C. to 100° C.

Abstract: Rinse off hair treatment compositions comprise particles wherein at least 90% by weight of the particles have an average maximum dimension of from 10 nm to 300 &mgr;m, the particles comprising a silicone wax having one or more C3 to C40, branched or unbranched, saturated or unsaturated, optionally substituted hydrocarbon groups and the wax having a melting point of from 30° C. to 100° C. The compositions can be used in a method of treating hair which comprises: applying to the hair particles wherein at least 90% by weight of the particles have an average maximum dimension of from 10 &mgr;m to 300 &mgr;m, the particles comprising a silicone wax having one or more C3 to C40, branched or unbranched, saturated or unsaturated, optionally substituted hydrocarbon groups and the wax having a melting point of from 30° C. to 100° C.; and heating the hair to a temperature above the melting point of the particles. The method can act to condition the hair.

Abstract: A vibration isolator including a bearing support and an elastic member that communicates with a vibration source. The elastic member is capable of bending from an original position to assume a more or less bowed position in response to changes in a load applied to the midportion of the elastic member intermediate its ends and returning essentially to its original position when the original load is restored. The elastic member engages a friction-resistant bearing surface on the bearing support at a distance spaced from each of its ends and moves relative to the bearing surface in response to a bending of the elastic member. The apparatus may be tuned to effectively isolate a particular vibration frequency, for example, by altering the properties of the elastic member or by changing the distance between the points on the bearing support that engage the elastic member.

Abstract: A communications core implemented on a single programmable device. In one embodiment, the communications core may include a subsystem interconnect operable to connect the programmable device to computer; a message processor coupled to the subsystem interconnect, the message processor having an instruction set architecture that includes a data path configured to reduce hardware requirements and increase memory management capabilities; and a codec coupled to the message processor. The programmable device may also include an instruction data buffer coupled to the message processor; and a signal conditioner coupled to the codec.

Abstract: A method for potentiating the action of a serotonin reuptake inhibitor in increasing the availability of serotonin, norepinephrin and dopamine in the brain, comprising administering to a patient in need of such treatment a serotonin reuptake inhibitor in combination with an effective amount of a compound of the formula 1

Abstract: A single roller concrete finishing machine for finishing a concrete surface includes a primary motorized unit and a secondary unmotorized unit disposed on each side of a surface to be paved, with a single roller disposed on the unfinished surface which connects the primary unit and the secondary unit. The primary unit includes a first base having an elongated first handle having two ends, one end of the first handle being connected to the first base, and the other end of the first handle being connected to handlebars, below which an engaging lever is disposed. The secondary unit includes a second base with an elongated second handle similar to the first handle, but without the engaging lever. The handles of each of the primary unit and the secondary unit are swingably adjustable in a horizontal plane to aid in the leveling of the concrete surface to be finished. The primary unit has an engine mounted on the first base, and a mechanism to rotate the roller.

Abstract: A vibration isolator with an adjustable response. A vibration isolator for isolating a vibration source from a support structure include a base in engagement with the support structure and two supports connected to the base. At least one of the supports is slidably connected to the base. A flexible member having a generally elongate shape and an elongate length is supported by the two supports. The flexible member is attachable to the vibration source. Each support slidably engages the flexible member such that the flexible member can move relative to each support with the support that is slidably connected to the base being moveable along the elongate length of the flexible member. The vibration isolator preferably further comprises means for moving the slidably connected supports along the elongate length of the flexible member.

Abstract: Growth differentiation factor-10 (GDF-10) is disclosed along with its polynucleotide and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the GDF-10 polypeptide and polynucleotide sequences.

Abstract: A pipe support is provided that includes a frame capable of being placed around an existing pipe and a plurality of support members within the frame. The frame is a hollow cylinder that includes two connectable halves divided along the diameter of the hollow cylinder. The pipe support includes two bearing rings connected to the frame for supporting each of the plurality of members at a minimum of two contact points. Each of the two bearing rings include bearing points for each support member arranged in a cylindrical pattern concentric with the hollow cylinder frame. The pipe support includes means for rotating each of the support members at a first contact point with respect to a second contact point so that the support members engage a pipe placed within the pipe support. The support members are rods that provide vibration isolation to a pipe placed within the pipe support.