Abstract: A device for holding an implantable medical device includes a jar for receiving the implantable medical device, and a ring coupleable to the jar. The ring has a plurality of channels adapted to receive retaining features of the implantable medical device to stabilize the medical device within the jar.

Abstract: A device for holding an implantable medical device includes a jar for receiving the implantable medical device, and a ring coupleable to the jar. The ring has a plurality of channels adapted to receive retaining features of the implantable medical device to stabilize the medical device within the jar.

Abstract: An asset bundle package is created with asset bundle package records for at least two user types and from one or more mobile phone service operators. The asset bundle package and asset bundle record selection criteria are installed on a mobile computing device. A boot routine uses the asset bundle record selection criteria to select asset bundle records required to configure the mobile computing device for at least one of the two user types.

Abstract: A method of assembling a prosthetic heart valve includes providing a collapsible and expandable stent having an annulus section and an aortic section. The annulus section has a first diameter in a relaxed condition and a second diameter less than the first diameter in a collapsed condition. A constraint is applied to the stent to constrain the annulus section to a predetermined diameter between the first and second diameters. Applying a cuff and/or a plurality of leaflets to the stent in the constrained condition enables less material to be used. The resultant prosthetic valve is therefore able to be collapsed to a smaller diameter for introduction into a patient.

Abstract: A method of assembling a prosthetic heart valve includes providing a collapsible and expandable stent having an annulus section and an aortic section. The annulus section has a first diameter in a relaxed condition and a second diameter less than the first diameter in a collapsed condition. A constraint is applied to the stent to constrain the annulus section to a predetermined diameter between the first and second diameters. Applying a cuff and/or a plurality of leaflets to the stent in the constrained condition enables less material to be used. The resultant prosthetic valve is therefore able to be collapsed to a smaller diameter for introduction into a patient.

Abstract: This device employs a visible laser module that will typically be a laser diode with an output beam mechanically aligned to the GoPro camera lens and its FOV (Field of View). This device is small and lightweight and can either be built into any part of the GoPro assembly or can be attached to part of the camera assembly. The housing includes the laser module, On/Off switch, batteries, tilt switch, and the required electrical interconnections.

Abstract: A prosthetic heart valve includes a collapsible and expandable stent and a plurality of commissure features disposed on the stent. A collapsible and expandable valve assembly includes a plurality of leaflets connected to the plurality of commissure features, each commissure feature including a body having a proximal end and a distal end. A plurality of eyelets is arranged in rows and columns on the body for distributing load from the plurality of leaflets.

Abstract: An asset bundle package is created with asset bundle package records for at least two user types and from one or more mobile phone service operators. The asset bundle package and asset bundle record selection criteria are installed on a mobile computing device. A boot routine uses the asset bundle record selection criteria to select asset bundle records required to configure the mobile computing device for at least one of the two user types.

Abstract: A device, comprising a flow controller. The flow controller includes a body having walls that define a channel within the body, and a passive flow control valve. The passive control valve has a moveable member that includes a thermal shape memory material, the moveable member configured to change an aperture size in the channel in response to a reversible temperature-induced shape transformation of the thermal shape memory material.

Abstract: A photonics assembly (8-16) is housed within an hermetically sealed container (24) mounted within an outer container (20), and is cooled by a fluidic arrangement comprising a liquid flow path (28) defined between the outer container and the sealed container, the outer container having a liquid inlet and a liquid outlet (30, 32), whereby cooling liquid can flow around the hermetically sealed container to remove heat. The photonics assembly including photonics devices, has a composite thermally conductive substrate (17, 19) contacting a thermally conductive wall (22) of the sealed container, whereby the cooling liquid cools said photonics devices. Liquid flow passageways (48-66) are provided in wall (22) and substrate (17, 19) for improving fluidic cooling.

Abstract: A delivery device for a collapsible medical device may include a handle and a delivery assembly having a compartment for receiving the medical device. A catheter member may extend from the handle to the delivery assembly. The catheter member may have a first portion with a first compliance value and a second portion with a second compliance value different from the first compliance value. An internally threaded member may be fixedly connected to the delivery assembly. An externally threaded member may have a first portion operatively connected to the actuation member and a second portion threadedly coupled to the internally threaded member so that manipulation of the actuation member causes axial movement of the compartment relative to the catheter member.

Abstract: An apparatus (1) is for DNA amplification with quantitative measurements. A biological sample is held in a cell (2) for the amplification, the cell (2) defining a single space within which the sample rotates. On one side a copper heater (3) is located to supply heat to the cell (2), and on the other side there is a cooling copper block (4) withdrawing heat from the cell. The locations of the heater (3) and the cooling block (4) generate a natural convection loop internally within the cell (2) without need for active cooling—the block (4) passively cooling by withdrawing heat from the direction of the heater (3). A detector (9, 27) captures readings in real time and a processor (10) generates an S-curve for change of sample emission with time. The S-curve (FIGS. 4 and 5) also includes a thermal cycle number corresponding to the time parameter, so that the S-curve is given in the traditional qPCR intensity vs. cycle number.

Abstract: An assembly for collapsing a self-expanding prosthetic heart valve includes a compression member, a support member and a constricting member. The compression member has a tapered wall between its first open end and its second open end, the tapered wall defining an open space adapted to receive the valve. The support member has a base and a recess adapted to receive an end of the valve. The support member and the compression member are movable toward one another to compress the valve and push it through a relatively small aperture in the second open end of the compression member. The second end of the constricting member is sized to receive the compressed valve from the second open end of the compression member for loading into a delivery device.

Abstract: An introducer provides access to a surgical site in a patient. The introducer includes a proximal housing configured to be positioned outside the patient and a sheath extending from the proximal housing to a distal end of the introducer. One or more handles may be housed at least partially within the proximal housing and configured to translate axially in proximal and distal directions with respect to the proximal housing. A securing element may be slideably coupled to the sheath and may have a flange extending radially outwardly from the sheath. A radially expanding portion of the sheath may have a first edge, a second edge, and a middle section extending from the first edge to the second edge. The sheath portion may have a rolled configuration in which the middle section at least partially overlies the first edge, and the second edge at least partially overlies the middle section.

Abstract: An apparatus comprising a fluid-circulator loop configured to be located on a circuit board, wherein a heat-removal portion of the fluid-circulator loop is configured to be located adjacent to an optical transceiver module on the circuit board.

Abstract: An asset bundle package is created with asset bundle package records for at least two user types and from one or more mobile phone service operators. The asset bundle package and asset bundle record selection criteria are installed on a mobile computing device. A boot routine uses the asset bundle record selection criteria to select asset bundle records required to configure the mobile computing device for at least one of the two user types.

Abstract: An apparatus includes a reservoir to hold a volume of liquid, a port to inject a flow of gas into a lower portion of the reservoir, and a structure to transform the flow of gas into one or more streams of bubbles in said liquid. The reservoir has a port for injecting the gas into a lower region of the volume of liquid and has a top opening to release the injected gas therefrom. The apparatus includes one or more active electronic or optical devices located in the reservoir or located physically adjacent and in thermal contact with the reservoir such that the volume of the liquid is able to absorb part of heat produced by the one of more electronic or optical devices.

Abstract: A delivery device for a collapsible heart valve includes an operating handle and a catheter assembly. The operating handle includes a frame defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, and a coupler having locked and unlocked conditions, the coupler being operatively connected to the carriage assembly for movement therewith. The catheter assembly includes a shaft around which a valve-receiving compartment is defined, the shaft being operatively connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly for movement therewith between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve.

Abstract: The present disclosure generally relates to protein binding agents, such as protein kinase binding agents of general Formula (I). The protein binding agents may be provided attached to a solid support and may be used, for example, to detect the presence of a broad range of proteins in a sample. Methods of synthesizing the protein binding agents, and kits comprising the protein binding agents, are also disclosed.

Abstract: A device for repositioning an implant within a lumen of a subject including (a) a catheter having forward and rearward ends and a collapsible and expansible stop element mounted adjacent the forward end of the catheter, the stop element being adapted to engage a wall of the lumen when expanded and to provide one or more passages extending from a rear side of the stop element to a forward side of the stop element when the stop element is expanded and engaged with the wall of the lumen and (b) one or more snares, each snare having engagement features, the stop element and the snares being constructed and arranged so that the snares can be positioned extending through the one or more passages with their engagement features forward of the stop element.