Patents by Inventor John M. Schaus

John M. Schaus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminotetralins as 5-HT1Dalpha agonists
    Publication number: 20020065312
    Abstract: A class of novel aminotetralins is disclosed useful as 5-HT1D&agr; agonists.
    Type: Application
    Filed: October 3, 2001
    Publication date: May 30, 2002
    Inventors: John M. Schaus, Clint D. Walker, Yao-Chang Xu
  • Aminotetralins as 5-HT1D &agr; Agonists
    Patent number: 6355674
    Abstract: A class of novel aminotetralins is disclosed useful as 5-HT1D&agr; agonists.
    Type: Grant
    Filed: May 2, 2000
    Date of Patent: March 12, 2002
    Assignee: Eli Lilly and Company
    Inventors: John M Schaus, Clint D Walker, Yao-Chang Xu
  • Compounds having effects on serotonin-related systems
    Patent number: 6172073
    Abstract: A series of hetero-oxy alkanamines are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1A receptor. The compounds are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal, and for the treatment of depression and other conditions for which serotonin reuptake inhibitors are used.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: January 9, 2001
    Assignee: Eli Lilly and Company
    Inventors: James E. Audia, David J. Hibschman, Joseph H. Krushinski, Jr., Thomas E. Mabry, Jeffrey S. Nissen, Kurt Rasmussen, Vincent P. Rocco, John M. Schaus, Dennis C. Thompson, David T. Wong
  • 5-HT.sub.4 agonists and antagonists
    Patent number: 6117882
    Abstract: Compounds of formula I: ##STR1## are used as antagonists and partial agonists for the serotonin receptor 5-HT.sub.4 and provide therapeutic methods for treatment of disorders caused by or affected by dysfunction of the 5-HT.sub.4 receptor.
    Type: Grant
    Filed: June 23, 1999
    Date of Patent: September 12, 2000
    Assignee: Eli Lilly and Company
    Inventors: John M. Schaus, Marlene L. Cohen, Dennis C. Thompson
  • 5-HT.sub.4 agonists and antagonists
    Patent number: 6069152
    Abstract: Compounds of formula I: ##STR1## are used as antagonists and partial agonists for the serotonin receptor 5-HT.sub.4 and provide therapeutic methods for treatment of disorders caused by or affected by dysfunction of the 5-HT.sub.4 receptor.
    Type: Grant
    Filed: October 7, 1997
    Date of Patent: May 30, 2000
    Assignee: Eli Lilly and Company
    Inventors: John M. Schaus, Marlene L. Cohen, Dennis C. Thompson
  • 5-HT.sub.IF -agonists effective in treating migraine
    Patent number: 5905084
    Abstract: This invention provides 5-HT.sub.1F agonists of Formula: ##STR1## where A-B, X, and R are as defined in the specification. The invention also encompasses pharmaceutical formulations employing the compounds or the invention as well as methods of treating conditions associated with 5-HT.sub.1F activation employing these compounds or compositions.
    Type: Grant
    Filed: November 14, 1997
    Date of Patent: May 18, 1999
    Assignee: Eli Lilly and Company
    Inventors: Sandra A. Filla, Brian M. Mathes, John M. Schaus
  • Indazolecarboxamides
    Patent number: 5817676
    Abstract: Indazolecarboxamides are used as antagonists and partial agonists for the serotonin receptor 5-HT.sub.4 and provide therapeutic methods for treatment of disorders caused by or affected by dysfunction of the 5-HT.sub.4 receptor.
    Type: Grant
    Filed: January 10, 1997
    Date of Patent: October 6, 1998
    Assignee: Eli Lilly and Company
    Inventors: John T. Catlow, Marlene L. Cohen, Michael O. Martinelli, John M. Schaus, Steven Swanson, Dennis C. Thompson, Thomas M. Wilson
  • Indazolecarboxamides
    Patent number: 5798367
    Abstract: Indazolecarboxamides are used as antagonists and partial agonists for the serotonin receptor 5-HT.sub.4 and provide therapeutic methods for treatment of disorders caused by or affected by dysfunction of the 5-HT.sub.4 receptor.
    Type: Grant
    Filed: January 10, 1997
    Date of Patent: August 25, 1998
    Assignee: Eli Lilly and Company
    Inventors: John T. Catlow, Marlene L. Cohen, Michael J. Martinelli, John M. Schaus, Steven Swanson, Dennis C. Thompson, Thomas M. Wilson
  • Compounds having effects on serotonin-related systems
    Patent number: 5789402
    Abstract: A series of hetero-oxy alkanamines are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1.sub.A receptor. The compounds are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal, and for the treatment of depression and other conditions for which serotonin reuptake inhibitors are used.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 4, 1998
    Assignee: Eli Lilly Company
    Inventors: James E. Audia, David J. Hibschman, Joseph H. Krushinski, Jr., Thomas E. Mabry, Jeffrey S. Nissen, Kurt Rasmussen, Vincent P. Rocco, John M. Schaus, Dennis C. Thompson, David T. Wong
  • 6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenz?CD!indoles
    Patent number: 5783590
    Abstract: 6-Heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz?cd!indoles are provided which are useful in modifying the function of serotonin in mammals.
    Type: Grant
    Filed: June 20, 1994
    Date of Patent: July 21, 1998
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, Michael E. Flaugh, David E. Lawhorn, Michael J. Martinelli, Charles J. Paget, Jr., John M. Schaus
  • 6 heterocyclic-4-amino-1,3,4,5-tetrahydrobenz?CD!indoles
    Patent number: 5750554
    Abstract: 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz-?cd!indoles are provided which are useful in modifying the function of serotonin in mammals.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: May 12, 1998
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, David E. Lawhorn, Charles J. Paget, Jr., John M. Schaus
  • Compounds having effects on serotonin-related systems
    Patent number: 5741789
    Abstract: A series of hetero-oxy alkanamines are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1.sub.A receptor. The compounds are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal, and for the treatment of depression and other conditions for which serotonin reuptake inhibitors are used.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: April 21, 1998
    Assignee: Eli Lilly and Company
    Inventors: David J. Hibschman, Joseph H. Krushinski, Jr., Kurt Rasmussen, Vincent P. Rocco, John M. Schaus, Dennis C. Thompson
  • 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz?CD ! indoles
    Patent number: 5736562
    Abstract: 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz?cd!indoles are provided which are useful in modifying the function of serotonin in mammals.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: April 7, 1998
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, David E. Lawhorn, Charles J. Paget, Jr., John M. Schaus
  • 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz ?cd! indoles
    Patent number: 5674884
    Abstract: 6-thiazolyl-4-amino-1,3,4,5-tetrahydrobenz?cd!indoles are provided which are useful in modifying the function of serotonin in mammals.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: October 7, 1997
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, David E. Lawhorn, Charles J. Paget, Jr., John M. Schaus
  • 6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenzn [cd] indoles
    Patent number: 5665744
    Abstract: 6-Thiadiazole-4-1-amino-1,2,2a,3,4,5-hexahydrobenz[c-d]indoles are provided which are useful in modifying the function of serotonin in mammals.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: September 9, 1997
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, David E. Lawhorn, Michael J. Martinelli, Charles J. Paget, Jr., John M. Schaus
  • 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD] indoles
    Patent number: 5665743
    Abstract: 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[cd]indoles are provided which are useful in modifying the function of serotonin in mammals.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: September 9, 1997
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, David E. Lawhorn, Charles J. Paget, Jr., John M. Schaus
  • 6-Heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD] indoles
    Patent number: 5665758
    Abstract: 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[cd]indoles are provided which are useful in modifying the function of serotonin in mammals.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: September 9, 1997
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, David E. Lawhorn, Charles J. Paget, Jr., John M. Schaus
  • 6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenz[cd]indoles
    Patent number: 5656653
    Abstract: 6-Heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles are provided which are useful in modifying the function of serotonin in mammals.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: August 12, 1997
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, David E. Lawhorn, Michael J. Martinelli, Charles J. Paget, Jr., John M. Schaus
  • 6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenz[cd]indoles
    Patent number: 5654324
    Abstract: 6-Heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz-[cd]indoles are provided which are useful in modifying the function of serotonin in mammals.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: August 5, 1997
    Assignee: Eli Lilly and Company
    Inventors: Richard N. Booher, David E. Lawhorn, Michael J. Martinelli, Charles J. Paget, Jr., John M. Schaus
  • Indazolecarboxamides
    Patent number: 5654320
    Abstract: Indazolecarboxamides are used as antagonists and partial agonists for the serotonin receptor 5-HT.sub.4 and provide therapeutic methods for treatment of disorders caused by or affected by dysfunction of the 5-HT.sub.4 receptor.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 5, 1997
    Assignee: Eli Lilly and Company
    Inventors: John T. Catlow, Michael J. Martinelli, John M. Schaus, Steven Swanson, Dennis C. Thompson