Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: The invention relates to processes for preparing isoindolin-1-one derivatives, and in particular processes for preparing (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid. The invention also relates to crystalline forms of the compound (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid and its salts.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: The invention relates to processes for preparing isoindolin-1-one derivatives, and in particular processes for preparing (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid. The invention also relates to crystalline forms of the compound (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid and its salts.

Abstract: A magnetized cable in which the magnetic force of the cable is configured to aid in aligning and maintaining alignment of the cable while the cable is being looped for storage and, when the cable is rolled or looped, the magnetic force will aid in keeping the cable coiled. Embodiments of the magnetized cable include an elongated flexible magnetic component (EFMC) of a pliable polymer such as rubber and/or one or more other suitable materials in combination with magnetic particles comprising iron, neodymium, ferrite, cobalt, nickel, and/or other suitable magnetic elements or compounds. The EFMC may be exposed to a strong magnetic field to produce a permanent magnet. The EFMC may be enclosed within a sheathing material of braided textile yarns or another suitable material.

Abstract: A magnetized cable in which the magnetic force of the cable is configured to aid in aligning and maintaining alignment of the cable while the cable is being looped for storage and, when the cable is rolled or looped, the magnetic force will aid in keeping the cable coiled. Embodiments of the magnetized cable include an elongated flexible magnetic component (EFMC) of a pliable polymer such as rubber and/or one or more other suitable materials in combination with magnetic particles comprising iron, neodymium, ferrite, cobalt, nickel, and/or other suitable magnetic elements or compounds. The EFMC may be exposed to a strong magnetic field to produce a permanent magnet. The EFMC may be enclosed within a sheathing material of braided textile yarns or another suitable material.

Abstract: A gyroscopic stabiliser for stabilising motion of an object includes a support for attaching to the object, a gimbal rotatably supported by the support to be rotatable around a first axis, a flywheel rotatably supported by the gimbal to be rotatable around a second axis relative to the gimbal, orthogonal to the first axis, and a rotary damper. The rotary damper has a chamber containing a damping fluid a vane that is rotatable within the chamber and that is coupled to the gimbal and a flow passage allowing flow of the damping fluid from the chamber on one side of the vane to the chamber on the other side of the vane when the vane is rotated.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient’s left phrenic nerve and the distal electrodes may stimulate a patient’s right phrenic nerve.

Abstract: The invention relates to processes for preparing isoindolin-1-one derivatives, and in particular processes for preparing (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid. The invention also relates to crystalline forms of the compound (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid and its salts.

Abstract: A gyroscopic stabiliser for stabilising motion of an object, the gyroscopic stabiliser comprising: a support for attaching to the object whose motion is to be stabilised; a gimbal rotatably supported by the support to be rotatable around a first axis relative to the support; and a flywheel rotatably supported by the gimbal to be rotatable around a second axis relative to the gimbal, the second axis being orthogonal to the first axis; wherein the gimbal is rotatably supported by the support at least partly within a maximum width of the gimbal along the first axis; and a maximum width of the gyroscopic stabiliser along the first axis is equal to, or substantially equal to, the maximum width of the gimbal along the first axis.

Abstract: A parcel storage assembly for remotely securing a parcel delivery includes a box that is positionable adjacent to an entry of a building to be accessible to a parcel delivery person. A lid is hingedly coupled to the box for opening and closing the box. A locking unit is coupled to the box and the locking unit engages the lid when the locking unit is turned on to inhibit the lid from is opened. The locking unit is in wireless communication with a personal electronic device to facilitate a user to remotely lock and unlock the box. A light emitter is coupled to the box to kill bacteria and sterilizing the parcel delivered by the parcel delivery person. A cooler is positionable within the box for receiving a food delivery positioned therein.

Abstract: A gyroscopic stabiliser for stabilising motion of an object, the gyroscopic stabiliser comprising: a support for attaching to the object whose motion is to be stabilised; a gimbal rotatably supported by the support to be rotatable around a first axis relative to the support; a flywheel rotatably supported by the gimbal to be rotatable around a second axis relative to the gimbal, the second axis being orthogonal to the first axis; and a rotary damper for damping rotation of the gimbal around the first axis relative to the support; wherein the rotary damper comprises: a chamber containing a damping fluid; a vane that is rotatable within the chamber and that is coupled to the gimbal; and a flow passage allowing flow of the damping fluid from the chamber on one side of the vane to the chamber on the other side of the vane when the vane is rotated, wherein the flow passage comprises a flow valve configured to provide substantially the same flow rate of fluid through the flow passage for different torques applied t

Abstract: A parcel storage assembly for remotely securing a parcel delivery includes a box that is positionable adjacent to an entry of a building to be accessible to a parcel delivery person. A lid is hingedly coupled to the box for opening and closing the box. A locking unit is coupled to the box and the locking unit engages the lid when the locking unit is turned on to inhibit the lid from is opened. The locking unit is in wireless communication with a personal electronic device to facilitate a user to remotely lock and unlock the box. A light emitter is coupled to the box to kill bacteria and sterilizing the parcel delivered by the parcel delivery person. A cooler is positionable within the box for receiving a food delivery positioned therein.

Abstract: A gyroscopic stabiliser for stabilising motion of an object, the gyroscopic stabiliser comprising: a support for attaching to the object whose motion is to be stabilised; a gimbal rotatably supported by the support to be rotatable around a first axis relative to the support; and a flywheel rotatably supported by the gimbal to be rotatable around a second axis relative to the gimbal, the second axis being orthogonal to the first axis; wherein the gimbal is rotatably supported by the support at least partly within a maximum width of the gimbal along the first axis; and a maximum width of the gyroscopic stabiliser along the first axis is equal to, or substantially equal to, the maximum width of the gimbal along the first axis.

Abstract: The invention relates to processes for preparing isoindolin-1-one derivatives, and in particular processes for preparing (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid. The invention also relates to crystalline forms of the compound (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid and its salts.

Abstract: Methods are provided for controlling voiding caused by gasses in solder joints of electronic assemblies. In various embodiments, a preform can be embedded into the solder paste prior to the component placement. The solder preform can be configured with a geometry such that it creates a standoff, or gap, between the components to be mounted in the solder paste. The method includes receiving a printed circuit board comprising a plurality of contact pads; depositing a volume of solder paste onto each of the plurality of contact pads; depositing a solder preform into each volume of solder paste; placing electronic components onto the printed circuit board such that contacts of the electronic components are aligned with corresponding contact pads of the printed circuit board; and reflow soldering the electronic components to the printed circuit board.

Abstract: Systems and methods for profiled and focused searching of litigation information allow a user to access specific legal information for use during litigation. The user can connect to a web site and access particular information from multiple sources based on the litigation task the user wishes to accomplish One litigation task is to create a litigation profile for a target, such as a particular litigant, attorney, judge, court, or firm. In this way, the user can perform focused and task-based searching to receive information about particular filings in particular locations, made by particular entities without knowing which sources contain certain pieces of the litigation information. For example, the user can receive all documents relating to summary judgment for patent infringement filed by a particular attorney in a particular court without specifying the source of information. In one aspect, the user can also access the source(s) upon receiving the results.

Abstract: The invention relates to a method for start-up and operation of a Fischer-Tropsch reactor comprising the steps of: (a) providing a reactor with a fixed bed of reduced Fischer-Tropsch catalyst that comprises cobalt as catalytically active metal; (b) supplying a gaseous feed stream comprising carbon monoxide and hydrogen to the reactor, wherein the gaseous feed stream comprises a nitrogen-containing compound other than molecular nitrogen in an initial concentration, wherein the initial concentration in the range of from 10 to 350 ppbv based on the volume of the gaseous feed stream; (c) converting carbon monoxide and hydrogen supplied with the gaseous feed stream to the reactor into hydrocarbons at a reaction temperature and at a set reactor productivity, whilst maintaining the initial concentration of the nitrogen-containing compound and maintaining the set reactor productivity during a first time period by adjusting the reaction temperature; (d) decreasing the concentration of the nitrogen-containing compound

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: The invention relates to a method for start-up and operation of a Fischer-Tropsch reactor comprising the steps of: (a) providing a reactor with a fixed bed of reduced Fischer-Tropsch catalyst that comprises cobalt as catalytically active metal; (b) supplying a gaseous feed stream comprising carbon monoxide and hydrogen to the reactor, wherein the gaseous feed stream comprises a nitrogen-containing compound other than molecular nitrogen in an initial concentration, wherein the initial concentration in the range of from 10 to 350 ppbv based on the volume of the gaseous feed stream; (c) converting carbon monoxide and hydrogen supplied with the gaseous feed stream to the reactor into hydrocarbons at a reaction temperature and at a set reactor productivity, whilst maintaining the initial concentration of the nitrogen-containing compound and maintaining the set reactor productivity during a first time period by adjusting the reaction temperature; (d) decreasing the concentration of the nitrogen- containing compound