Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: Methods are provided for controlling voiding caused by gasses in solder joints of electronic assemblies. In various embodiments, a preform can be embedded into the solder paste prior to the component placement. The solder preform can be configured with a geometry such that it creates a standoff, or gap, between the components to be mounted in the solder paste. The method includes receiving a printed circuit board comprising a plurality of contact pads; depositing a volume of solder paste onto each of the plurality of contact pads; depositing a solder preform into each volume of solder paste; placing electronic components onto the printed circuit board such that contacts of the electronic components are aligned with corresponding contact pads of the printed circuit board; and reflow soldering the electronic components to the printed circuit board.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Abstract: A method of sensing using a phase based transducer in which a transducer response is provided at multiple different levels of sensitivity. The different levels of sensitivity are used to produce an output which does not overscale across a wide range of signal levels. This is particularly useful for use in conjunction with multiplexed arrays of fiber optic sensors for seismic surveying. Methods of sensor calibration and noise reduction are also described.

Abstract: A series of substituted [1,3,5]triazin-2-yl derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.

Abstract: A fiber-optic sensor package (10) comprises a serial array of fiber-optic sensing coils (14, 16, 18, 20, 22) each of which is comprised in a respective fiber-optic sensor. Four (14, 16, 18, 22) of the coils are housed in a protective casing (24). One of the coils (22) is comprised in a fiber-optic electromagnetic field sensor. The other coils are comprised in respective fiber-optic geophones and/or hydrophones. A single package of the invention allows detection of both seismic and electromagnetic signals. An array of packages of the invention provides detection of both seismic and electromagnetic signal at a series of positions over a long distance or wide area, thus avoiding the need for two conventional arrays. A packages of the invention, and an array of such packages, require little or no electrical power input.

Abstract: A sensor arrangement for monitoring a oil reservoir comprises a sensor array (1) comprising a plurality of sensor units (5) located over an area to be monitored; an interrogator unit (30) comprising a transmitter (402) for transmitting optical signals and receiver for obtaining data on the reservoir from the sensor units, a demodulator (418) for demodulating the received signals, and a recorder (420) for recording the demodulated signals. The arrangement includes an uplink optical cable (408) for transmitting the signals to the sensor array and a downlink optical cable (410) for transmitting signals from the array to the receiver. At least one of the optical cables has an optical amplifier (412, 414). The arrangement enables the interrogator to be remote from the array, for example 150 km or more, obviating the need for significant power to be supplied at the array.

Abstract: A series of substituted [1,3,5]triazin-2-yl derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.

Abstract: Disclosed herein are compounds of formula (I) and: wherein: X is Ar—C(O)CH(R20)— or Ar1—NHC(O)CH2—; and Ar is: naphthyl optionally substituted with one or more groups Y; pyridyl optionally substituted with one or more groups Z; or the group Ar1 etc, these compounds being useful for treating neurological diseases such as schizophrenia, dementia or attention deficit disorder.

Abstract: Demodulation apparatus for demodulating phase-modulated signals comprises a quadrature signal generator (QSG) for generating in-phase (I) and quadrature-phase (Q) signals in response to an unmodulated input signal. The QSG provides fast frequency tracking of the input signal and excludes any high-frequency content the input signal.

Abstract: A method of sensing using a phase based transducer in which a transducer response is provided at multiple different levels of sensitivity. The different levels of sensitivity are used to produce an output which does not overscale across a wide range of signal levels. This is particularly useful for use in conjunction with multiplexed arrays of fibre optic sensors for seismic surveying. Methods of sensor calibration and noise reduction are also described.

Abstract: Disclosed are N-aroyl cyclic amine derivatives having the formula: where the variables are as define herein, and their use as pharmaceuticals, specifically as orexin receptor antagonists.

Abstract: Disclosed are N-aroyl cyclic amine derivatives having the formula: where the variables are as define herein, and their use as pharmaceuticals, specifically as orexin receptor antagonists.

Abstract: A multipurpose track and radius plate burner apparatus that permits beveled and nonbeveled burning in a workpiece is provided. The apparatus provides capability to make circle or radius burns as well as track or straight line burns. The apparatus may be used with all standard torch heads as well as mini torches. The apparatus has other applications, including making burns in corners or restricted areas, use as a protractor and use as trammel points.

Abstract: Disclosed are N-aroyl cyclic amine derivatives having the formula: where the variables are as define herein, and their use as pharmaceuticals, specifically as orexin receptor antagonists.

Abstract: Disclosed are N-aroyl cyclic amine derivatives having the formula: where the variables are as define herein, and their use as pharmaceuticals, specifically as orexin receptor antagonists.