Patents by Inventor John O'Neill

John O'Neill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT AND PREVENTION OF A NEURODEGENERATIVE DISORDER
    Publication number: 20220401414
    Abstract: The present invention relates to a compound of formula (I): for use in the treatment or prevention of a neurodegenerative disorder.
    Type: Application
    Filed: November 6, 2020
    Publication date: December 22, 2022
    Inventors: Matthew COOPER, Luke Anthony John O'NEILL
  • TREATMENT OF ARTHRITIS
    Publication number: 20220395490
    Abstract: The present invention relates to a compound of formula (I) for use in the treatment or prevention of arthritis.
    Type: Application
    Filed: November 6, 2020
    Publication date: December 15, 2022
    Inventors: Matthew COOPER, Luke Anthony John O'NEILL
  • MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF
    Publication number: 20220340604
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: March 25, 2022
    Publication date: October 27, 2022
    Inventors: Kristina Michelle FETALVERO, Sridhar Narayan, David John O'Neill, Eddine Saiah, Shomit Sengupta
  • RAPAMYCIN ANALOGS AND USES THEREOF
    Publication number: 20220267352
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: January 24, 2022
    Publication date: August 25, 2022
    Inventors: David John O'NEILL, Eddine SAIAH, Seong Woo Anthony KANG
  • FIBROSIS-SPECIFIC CELL CULTURE SUBSTRATE AND METHODS OF USE
    Publication number: 20220267720
    Abstract: An in vitro cell culture substrate is disclosed. The substrate comprises a decellularized tissue-specific extracellular matrix, wherein the tissue-specific extracellular matrix is derived from fibrotic tissue. A method of method of assessing an in vitro fibrotic cell culture is also disclosed. The method comprises providing one or more substrates comprising decellularized tissue-specific extracellular matrix derived from fibrotic tissue, where each substrate is provided in segregated manner. The method further comprises culturing native cells in each substrate to form a fibrotic cell culture. The method further comprises assessing at least one characteristic of each fibrotic cell culture.
    Type: Application
    Filed: July 23, 2020
    Publication date: August 25, 2022
    Inventors: John O'NEILL, Igal GERMANGUZ, Evelyn ARANDA, Jennifer XIONG, Natalia KISSEL, Alexandra NICHOLS
  • BIOMATERIALS DERIVED FROM TISSUE EXTRACELLULAR MATRIX
    Publication number: 20220211755
    Abstract: Region-specific extracellular matrix (ECM) biomaterials are provided. Such materials include acellular scaffolds, sponges, solutions, and hydrogels suitable for stem cell culture.
    Type: Application
    Filed: March 16, 2022
    Publication date: July 7, 2022
    Inventors: Donald O. Freytes, Gordana Vunjak-Novakovic, John O'Neill
  • Modulators of Sestrin-GATOR2 interaction and uses thereof
    Patent number: 11325924
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: July 29, 2020
    Date of Patent: May 10, 2022
    Assignee: NAVITOR PHARMACEUTICALS, INC.
    Inventors: Kristina Michelle Fetalvero, Sridhar Narayan, David John O'Neill, Eddine Saiah, Shomit Sengupta
  • Cell-seeded porous lung hydrogel sealant
    Patent number: 11291747
    Abstract: Disclosed are a biosealant system and method for treatment of a pulmonary air leak comprising applying the biosealant system to the locus of the air leak.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: April 5, 2022
    Assignee: The Trustees of Columbia University in The City of New York
    Inventors: Matthew Bacchetta, Brandon Guenthart, Jinho Kim, John O'Neill, Gordana Vunjak-Novakovic
  • CYCLICAL OBSTRUCTION COMMUNICATION SYSTEM
    Publication number: 20210266930
    Abstract: Techniques for improving data rates at mobile terminals that are subject to periodic channel interruptions in a beyond-line-of-sight communication system are disclosed, including improved encoding and decoding systems that identify blockages and modify receiver operation during blockages to reduce data errors. In certain embodiments, encoding, symbol mapping, interleaving, and use of unique periodic identifiers function to enable a series of packets that may be received in a blockage impaired channel with reduced errors.
    Type: Application
    Filed: December 10, 2020
    Publication date: August 26, 2021
    Inventors: Donald Wilcoxson, John O'Neill, Daniel Chester, Brian Sleight, Changping Li
  • RAPAMYCIN ANALOGS AND USES THEREOF
    Publication number: 20210220339
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: November 25, 2020
    Publication date: July 22, 2021
    Inventors: Eddine SAIAH, David John O'NEILL, Seong Woo Anthony KANG
  • RAPAMYCIN ANALOGS AND USES THEREOF
    Publication number: 20210186935
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: December 4, 2020
    Publication date: June 24, 2021
    Inventors: David John O'NEILL, Eddine SAIAH, Seong Woo Anthony KANG
  • Rapamycin analogs and uses thereof
    Patent number: 10980784
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: April 20, 2021
    Assignee: NAVITOR PHARMACEUTICALS, INC.
    Inventors: Eddine Saiah, David John O'Neill, Seong Woo Anthony Kang
  • BACILLUS COMPOSITIONS AND METHODS OF USE WITH RUMINANTS
    Publication number: 20210077545
    Abstract: Bacillus strains, compositions and methods are disclosed for reducing growth of microorganisms in a feed. Bacillus strains, compositions and methods are disclosed for providing beneficial effects to animals, including but not limited to increasing performance of the animal.
    Type: Application
    Filed: September 23, 2020
    Publication date: March 18, 2021
    Applicant: Church & Dwight Co., Inc.
    Inventors: Thomas Rehberger, John O'Neill, Alexandra Smith, Mari Ellen Davis, Jesse Thompson, Jennifer Schissel
  • Cyclical obstruction communication system
    Patent number: 10932285
    Abstract: Techniques for improving data rates at mobile terminals that are subject to periodic channel interruptions in a beyond-line-of-sight communication system are disclosed, including improved encoding and decoding systems that identify blockages and modify receiver operation during blockages to reduce data errors. In certain embodiments, encoding, symbol mapping, interleaving, and use of unique periodic identifiers function to enable a series of packets that may be received in a blockage impaired channel with reduced errors.
    Type: Grant
    Filed: October 1, 2019
    Date of Patent: February 23, 2021
    Assignee: Viasat Inc.
    Inventors: Donald Wilcoxson, John O'Neill, Daniel Chester, Brian Sleight, Changping Li
  • MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF
    Publication number: 20210047347
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: July 29, 2020
    Publication date: February 18, 2021
    Inventors: Kristina Michelle FETALVERO, Sridhar NARAYAN, David John O'NEILL, Eddine SAIAH, Shomit SENGUPTA
  • Phenyl amino piperidine mTORC inhibitors and uses thereof
    Patent number: 10844013
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: November 24, 2020
    Assignee: NAVITOR PHARMACEUTICALS, INC.
    Inventors: David John O'Neill, Eddine Saiah, Seong Woo Anthony Kang, Andrew Brearley, Jonathan Bentley
  • compositions and methods of use with ruminants
    Patent number: 10835561
    Abstract: Bacillus strains, compositions and methods are disclosed for reducing growth of microorganisms in a feed. Bacillus strains, compositions and methods are disclosed for providing beneficial effects to animals, including but not limited to increasing performance of the animal.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: November 17, 2020
    Assignee: Church & Dwight Co., Inc.
    Inventors: Thomas Rehberger, John O'Neill, Alexandra Smith, Mari Ellen Davis, Jesse Thompson, Jennifer Schissel
  • Modulators of Sestrin-GATOR2 interaction and uses thereof
    Patent number: 10752644
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: August 25, 2020
    Assignee: NAVITOR PHARMACEUTICALS, INC.
    Inventors: Kristina Michelle Fetalvero, Sridhar Narayan, David John O'Neill, Eddine Saiah, Shomit Sengupta
  • Systems and methods for locally processing a financial transaction
    Patent number: 10733611
    Abstract: Embodiments of the disclosure enable a merchant system to locally process one or more financial transactions at the merchant system. The merchant system receives a payment request associated with a financial transaction, determines a network communication status associated with a network interface device coupleable to a payment processing network, and, on condition that the network communication status does not satisfy a network communication threshold, obtains an account threshold associated with a cardholder account, generates transaction data associated with the financial transaction based on the account threshold, presents an indication associated with the financial transaction, and stores the transaction data for later transmission of the transaction data to the payment processing network. Aspects of the disclosure provide for processing one or more financial transactions at a merchant system independent of a payment processing network.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: August 4, 2020
    Assignee: MASTERCARD INTERNATIONAL INCORPORATED
    Inventors: John O'Neill, Jennifer Boschert, Shasidhar Vemireddy
  • PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF
    Publication number: 20200207716
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: August 7, 2019
    Publication date: July 2, 2020
    Inventors: David John O'Neill, Eddine Saiah, Seong Woo Anthony Kang, Andrew Brearley, Jonathan Bentley