Abstract: A composition and method for the treatment of the side-effects associated with the administration of cancer chemotherapeutic agents involves the oral ingestion of a slow release capsule containing adenine and orotate. The administration of a protein pump inhibitor decreases systemic absorption of orotate and the administration of allopurinol decreases the formation of 2,8-dihydroxy adenine from adenine. In an alternative embodiment, cationic liposomes contain purine/pyrimidine precursors. The cationic liposomes bind to the cells lining the mucosa of the intestinal tract and then the contents of the cationic liposome are then taken up in the interior of the cells to prevent the metabolism of the cancer treatment drug 5-FU into a toxic species.

Abstract: Systems and methods detect electrical activity in the human brain in the form of the generated magnetic fields and map the magnetic field strength to the surface of the cerebral cortex. By mapping the measured magnetic fields to the sulcal-defined gyrus of the cerebral cortex rather than to its three-dimensional volume, the data complexity and the resulting image are dramatically reduced. The device allows an inventory of brain function, including, but not limited to, vision, sound, sensory, and cognition, with the sensors placed over the corresponding region or regions of interest of the brain.

Abstract: A computer enabled system and method aggregates data describing a particular subject. The data is then divided into a predetermined group of categories which are graphically displayed according to a predetermined pattern. Distortions in the data or anomalies in the data are made visually apparent. Associated with the display is a prioritized array of interventions recommended in response to the distortions in the data or anomalies appearing in the data.

Abstract: The invention encompasses protectant agents including uracil or a metabolite thereof that effectively prevent and/or treat the cutaneous toxicities and dermatological side-effects associated with chemotherapeutic agents. Additionally, and surprisingly compositions including uracil or a metabolite thereof are effective for treating or preventing various dermatoses.

Abstract: A composition and method for the treatment of the side-effects associated with the administration of cancer chemotherapeutic agents involves the oral ingestion of a slow release capsule containing adenine and orotate. The administration of a protein pump inhibitor decreases systemic absorption of orotate and the administration of allopurinol decreases the formation of 2,8-dihydroxy adenine from adenine. In an alternative embodiment, cationic liposomes contain purine/pyrimidine precursors. The cationic liposomes bind to the cells lining the mucosa of the intestinal tract and then the contents of the cationic liposome are then taken up in the interior of the cells to prevent the metabolism of the cancer treatment drug 5-FU into a toxic species.

Abstract: The invention encompasses protectant agents including uracil or a metabolite thereof that effectively prevent and/or treat the cutaneous toxicities and dermatological side-effects associated with chemotherapeutic agents. Additionally, and surprisingly compositions including uracil or a metabolite thereof are effective for treating or preventing various dermatoses.

Abstract: Computer-enabled systems and methods aggregate data related to a particular subject or field and present the data in a simplified display. The data is divided into predetermined categories, which are graphically displayed in a predetermined arrangement. Systems and methods differentiate and visually display critical data abnormalities separately from non-critical data. The systems and methods enable an observer to identify the critical deviations or anomalies of data with respect to a predetermined base line by an intuitive visual display of all of the data from any sized data universe on a single screen. The data is indexed at multiple display levels such as a stack of one patient's data, a stack of all patient data for the universe of patients of a single practitioner, or a group of practitioners of any size. A portion of the display preferably may be selected and expanded to show only that portion in greater detail.

Abstract: Methods, compositions, and kits are presented for local tissue protection during systemic administration of anticancer therapeutic agents.

Abstract: The invention encompasses protectant agents including uracil or a metabolite thereof that effectively prevent and/or treat the cutaneous toxicities and dermatological side-effects associated with chemotherapeutic agents. Additionally, and surprisingly compositions including uracil or a metabolite thereof are effective for treating or preventing various dermatoses.

Abstract: The invention encompasses protectant agents including uracil or a metabolite thereof that effectively prevent and/or treat the cutaneous toxicities and dermatological side-effects associated with chemotherapeutic agents. Additionally, and surprisingly compositions including uracil or a metabolite thereof are effective for treating or preventing various dermatoses.

Abstract: Methods, compositions, and kits are presented for local tissue protection during systemic administration of anticancer therapeutic agents.

Abstract: Methods, compositions, and kits are presented for local tissue protection during systemic administration of anticancer therapeutic agents.

Abstract: Methods, compositions, and kits are presented for local tissue protection during systemic administration of anticancer therapeutic agents.

Abstract: A composition and method for the treatment of the side-effects associated with the administration of cancer chemotherapeutic agents involves the oral ingestion of cationic liposomes containing the substrates orotate, UMP and AMP. The cationic liposomes bind to the cells lining the mucosa of the intestinal tract and then the contents of the cationic liposome are then taken up in the interior of the cells to prevent the metabolism or anabolism of the cancer treatment drug 5-FU into a toxic species.

Abstract: A computer enabled system and method aggregates data describing a particular subject. The data is then divided into a predetermined group of categories which are graphically displayed according to a predetermined pattern. Distortions in the data or anomalies in the data are made visually apparent. Associated with the display is a prioritized array of interventions recommended in response to the distortions in the data or anomalies appearing in the data.

Abstract: Methods, compositions, and kits are presented for local tissue protection during systemic administration of anticancer therapeutic agents.

Abstract: The invention encompasses protectant agents including uracil or a metabolite thereof that effectively prevent and/or treat the cutaneous toxicities and dermatological side-effects associated with chemotherapeutic agents. Additionally, and surprisingly compositions including uracil or a metabolite thereof are effective for treating or preventing various dermatoses.

Abstract: Methods, compositions, and kits are presented for local tissue protection during systemic administration of anticancer therapeutic agents.

Abstract: Methods, compositions, and kits are presented for local tissue protection during systemic administration of anticancer therapeutic agents.

Abstract: Methods, compositions, and kits are presented for local tissue protection during systemic administration of anticancer therapeutic agents.