Patents by Inventor John (Qiang) Zhang

John (Qiang) Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12383570
    Abstract: Methods of feeding animals are disclosed wherein providing feed additives are provided that modulate the gut microbiome to improve the health, nutrition, and growth performance. Methods of modulating the microbial species present in the gastrointestinal tract of an animal are also disclosed. Such modulation includes, for example, modulating the level or function of microbial species.
    Type: Grant
    Filed: January 23, 2024
    Date of Patent: August 12, 2025
    Assignee: DSM IP Assets B.V.
    Inventors: Stephane Duval, John Michael Geremia, Lisa Ann Laprade, April Waguespack-Levy, Estefania Perez Calvo, Ghislain Schyns, Viviane Verlhac, Joshua Thomas Claypool
  • Patent number: 12383572
    Abstract: The present invention relates to methods of treating ovarian cancer in a subject by administering to the subject by evaluating the subject's expression levels of specific biomarkers or angiogenic an anti-activin-A compound, such as an anti-activin-A antibody or an activin-A-binding receptor. In some embodiments, at least two compounds are administered to the subject, where the first compound is an anti-activin A compound, and the second compound is a chemotherapeutic compound, for example capecitabine. The invention further relates to methods of identifying subjects for treatment factors.
    Type: Grant
    Filed: December 22, 2022
    Date of Patent: August 12, 2025
    Assignees: AMGEN INC., Atara Biotherapeutics, Inc.
    Inventors: Huiquan Han, Christopher Michael Haqq, Isaac Ciechanover, Xiaolan Zhou, John Zhao-Nian Lu
  • Patent number: 12384639
    Abstract: A wrapping or roll-up device including a base, one or more connectors, an arm, and a handle. In embodiments, one or more connectors are connected to the base and are configured to connect the device to a wall or support structure, and/or the arm includes an aperture. In embodiments, a handle includes an extended portion and a grip portion, and at least a portion of the extended portion is configured to extend through the aperture. Further, with embodiments, the extended portion includes a slot disposed about an end of the extended portion. Embodiments may include a tensioner. Methods for wrapping or rolling up an article such as a wrap are also disclosed.
    Type: Grant
    Filed: November 22, 2021
    Date of Patent: August 12, 2025
    Inventors: Catrina Guenther, John P. Guenther
  • Patent number: 12384849
    Abstract: The present invention is directed to a CH3-containing molecule comprising (a) a first polypeptide comprising a CH3 domain and a negatively charged domain comprising consecutive negatively charged amino acid residues; and (b) a second polypeptide comprising a CH3 domain and a positively charged domain comprising consecutive positively charged amino acid residues. Also provided are methods for conjugating synthetic molecules to a multi-specific antigen binding molecule.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: August 12, 2025
    Assignee: AMGEN INC.
    Inventors: John K. Kawooya, Alex W. Jacobitz, Christopher Mohr, Stephen Smith, Kevin Graham, Ray Lieh Yoon Low, Oliver Thiel, Dante Romanini, Victoria Wagner, Neeraj J. Agrawal
  • Patent number: 12385994
    Abstract: Systems and methods are disclosed for increasing a nuclear spin polarization of a target compound. In accordance with such systems and methods, a first non-thermal equilibrium nuclear spin polarization can be imparted to at least one source atom of a source compound, the source atom having a nuclear gyromagnetic ratio of at least 12 megahertz per tesla (MHz/T). A first solution can be obtained that includes the source compound and a target compound. The at least one source atom can be present in a source concentration of at least 0.1 molar (M) in the first solution. A second non-thermal equilibrium nuclear spin polarization of at least 0.01% can be imparted to the at least one target atom of the target compound via a nuclear Overhauser effect (NOE) transfer of the first non-thermal equilibrium nuclear spin polarization to the at least one target atom.
    Type: Grant
    Filed: July 27, 2023
    Date of Patent: August 12, 2025
    Assignee: NVision Imaging Technologies GmbH
    Inventors: Ilai Schwartz, Anna Parker, Stephan Knecht, Tim Eichhorn, John Blanchard
  • Patent number: 12385222
    Abstract: A work machine having a powertrain, an engine, a torque converter operably connected to the engine, a transmission, a selector interface, and a control system. The control system is configured to: receive a machine activation signal from the selector interface indicative of operation of the work machine; receive machine conditions to determine an optimal gear for next pass; and send a gear pass signal to command execution of a directional shift and a speed shift simultaneously when a gear ratio setting of the transmission is indicative of a second gear ratio.
    Type: Grant
    Filed: August 17, 2022
    Date of Patent: August 12, 2025
    Assignee: Caterpillar Inc.
    Inventors: Aaron Y Ho, John J Krone, Jordan A. Mangels, Jeremy D. Folkerts, Mehul Yadav
  • Patent number: 12386400
    Abstract: An information handling system motherboard interfaces with other components, such as an I/O board and a display, through a cable backplane having an M.2 edge card connector and coupled to a housing with a snap in cable retainer. The motherboard slides into position at the housing to have an edge card extending past one side to engage into the edge card connector. The cable backplane is a flexible cable that routes through the hinge up lid housing portion of the system to communicate with a display and/or camera in the lid portion, or to route back into the main housing portion to communicate with an I/O board.
    Type: Grant
    Filed: September 8, 2023
    Date of Patent: August 12, 2025
    Assignee: Dell Products L.P.
    Inventors: John Trevor Morrison, Jace W. Files, Chiu-Jung Tsen
  • Patent number: 12388653
    Abstract: Disclosed are various embodiments for generating and verifying stateful hash-based signatures. A message hash of a message is generated using a cryptographic hash function. Then, the message hash is split into a predefined number of parts of equal size. Next, a value of a signature debt is calculated for each of the predefined number of parts of the message hash. Subsequently, a respective signature part is calculated for each of the predefined number of parts of the message hash by applying the cryptographic hash function to a respective portion of a private key for a number of times equal to the value of the signature debt. Next, the respective signature parts are concatenated to generate a signature for the message.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: August 12, 2025
    Assignee: AMERICAN EXPRESS TRAVEL RELATED SERVICES COMPANY, INC.
    Inventors: Hicham Lozi, Peter John Markall
  • Patent number: 12387218
    Abstract: The present disclosure relates to systems and methods to generate user or user group behavior similarities based on computing distances between individual users or user groups and without using demographic data, e.g., based on anonymized data. The methods include creating a multidimensional vector representation for each user in a group by summarizing user's behaviors across various categories. Based on the created vectors, distance calculation and nearest neighbor search are performed to locate users that are most similar to target users. The resulting distance metrics may be used to rank similarities. Additionally, dimensionality reduction may be performed to further distill the behavior information to make the disclosed methods suitable for a variety of analytics and modeling tasks.
    Type: Grant
    Filed: February 22, 2024
    Date of Patent: August 12, 2025
    Assignee: United Services Automobile Association (USAA)
    Inventors: John Gibson, Linqiu Wu
  • Patent number: 12388219
    Abstract: A power outlet, and associated method, for an electrical power supply strip. The power outlet includes a housing, an electrical connection for receiving first electrical power type, electrical components to change the first electrical power type to a second electrical power type, and a connection interface to supplying the second electrical power type. The power outlet housing has a body with a shape that corresponds to a shaped aperture of a main housing of the strip. A front portion of the power outlet housing is larger than the shaped aperture. An elastically deformable arm extends from the body and deforms as the arm passes through the shaped aperture of the main housing. An engagement portion of the arm retains the power outlet housing relative to the main housing.
    Type: Grant
    Filed: November 9, 2022
    Date of Patent: August 12, 2025
    Assignee: QUALTEK ELECTRONICS CORPORATION
    Inventors: Robert J. Nuti, John J. Hallums, III
  • Patent number: 12389700
    Abstract: Hybrid imaging systems incorporating conventional optical elements and metasurface elements with light sources and/or detectors, and methods of the manufacture and operation of such optical arrangements are provided. Systems and methods describe the integration of apertures with metasurface elements and refractive optics with metasurface elements in illumination sources and sensors.
    Type: Grant
    Filed: September 14, 2021
    Date of Patent: August 12, 2025
    Assignee: Metalenz, Inc.
    Inventors: Robert C. Devlin, John Graff
  • Publication number: 20250248843
    Abstract: Implant delivery devices, methods of device assembly and methods of using those devices are presented where the delivery device uses an automatic implant delivery mechanism that eliminates variability in pusher wire speeds by providing a needle assembly having one or more implants positioned within a proximal end of a needle cannula, a dampener assembly and a shuttle assembly located within a housing along with the activation member which holds the shuttle assembly in cocked or pre-tensioned state. A lock can be engaged with the activation member to prevent premature firing or triggering of the device.
    Type: Application
    Filed: April 23, 2025
    Publication date: August 7, 2025
    Applicant: ALCON INC.
    Inventors: Leo Anthony Trevino, Cheng Li, Tyler Pegoraro, Stuart Williams, Thomas Shepard, Peter Andrew Smith, Matthew Charles Walker, Andrew John Corson, Thomas Ralph Blackburn, III, Stephen James Couse
  • Publication number: 20250248640
    Abstract: A system, method and computer program for assessment of body movement's conditions or disorders are proposed. The system comprises several monitoring sensors to be attached to different body areas of a person to obtain biomechanical and/or physiological variables thereof according to a specified sensor configuration; a memory or database, having stored therein at least one of: control biomechanical and/or physiological variables and pathology biomechanical and/or physiological variables obtained. The variables being stored classified in three different categories: cardiac, kinematics and plantar-pressure.
    Type: Application
    Filed: April 19, 2023
    Publication date: August 7, 2025
    Inventors: Mireia CLARAMUNT MOLET, Sebastian IDELSOHN ZIELONKA, Felipe MIRALLES BARRACHINA, David MARÍ MARTÍNEZ, Carolina Mercedes MIGLIORELLI FALCONE, Meritxell GÓMEZ MARTÍNEZ, Paula SUBÍAS BELTRÁN, Silvia Julia ORTE DEL MOLINO, Xavier CREMADES ROSELL, Julita MEDINA CANTILLO, John VISSING, Maria Soledad MONTOLIO DEL OLMO
  • Publication number: 20250249031
    Abstract: One aspect of the present application relates to a storage stable pharmaceutical composition comprising a sulfated glycosaminoglycan having an average molecular weight ranging from 3,000 to 15,000 Daltons, and a pharmaceutical carrier, where the pharmaceutical carrier is mixed with the sulfated glycosaminoglycan, as well as this composition's use in a method of treating a subject for a medically observable improvement. Another aspect of the present application relates to a process for producing a storage stable purified sulfated glycosaminoglycan.
    Type: Application
    Filed: April 23, 2025
    Publication date: August 7, 2025
    Inventors: Thomas Michael VAUGHN, Joshua Alan HARRISON, Karl F. POPP, David J. FAIRFAX, Thomas Edward D'AMBRA, John QUINN
  • Publication number: 20250249619
    Abstract: Described herein are examples of a perforating device for perforating a textile material, such as carpet or textile underlayment. In an example, the perforating device includes a multi-blade assembly rotationally driven by a motor. The blade assembly can be coupled to a rotary shaft such that the blades rotate with the shaft. The blades can include alternating teeth and gaps on their outer edges to create a plurality of parallel perforated cuts. Spacers can be positioned between the blades to separate them a predetermined distance. An anvil can be positioned below and adjacent the blade edges such that the teeth of the blades touch or nearly touch the anvil surface. The perforating cuts produce a textile that can be customized in terms of its size and shape at an installation site by hand, and without the need for any specialized tools or equipment.
    Type: Application
    Filed: February 3, 2025
    Publication date: August 7, 2025
    Inventors: John Thompson, Kelsey Finn, Samuel Thompson
  • Publication number: 20250252505
    Abstract: Methods and systems for predictively generating an insurance claim in response to detecting an imminent insurance-related event are provided. According to certain aspects, a smart home controller or insurance provider remote processor may store a first set of data received from smart devices disposed on, or proximate to, a property. This data may be analyzed to detect that an insurance-related event is imminent and calculate a likelihood that a property owner will file an insurance claim in response to damage caused by the imminent insurance-related event. If there is a sufficient likelihood that an insurance claim will be filed, the smart home controller or remote processor may store a second set of data received from the smart devices. Subsequently, according to certain aspects, the second set of data may be analyzed to prepopulate an automatically generated insurance claim with information detailing damage to the property caused by the insurance-related event.
    Type: Application
    Filed: March 31, 2025
    Publication date: August 7, 2025
    Inventors: Daryoush Hakimi-Boushehri, Jackie O. Jordan, II, Shawn M. Call, John H. Weekes, Ronny S. Bryant, Jennifer Criswell Kellett, Todd Binion, Elisabeth McDermeit, John Donovan
  • Publication number: 20250252706
    Abstract: A processor, method, and non-transitory computer-readable storage medium for processing template data and search data according to a search window applied to the search data. The search window comprising a set of offset positions. The processing is performed by a block matching engine (BME) that produces a tensor with difference values, and a convolutional engine (CE) that performs a convolutional operation on the tensor. The processing is performed in an iterative interleaved fashion, by dividing the set of offset positions into a plurality of subsets of offset positions. In parallel with processing of the first X offset positions by the CE, the BME generates the next X channels of the tensor, and which are subsequently pipelined through to the CE via an internal storage, etc.
    Type: Application
    Filed: February 2, 2024
    Publication date: August 7, 2025
    Inventors: John Wakefield BROTHERS, III, Metin Gokhan ÜNAL, Balaji VENU, Rune HOLM
  • Publication number: 20250253684
    Abstract: A battery charging system prevents or reduces deterioration of battery health due to fast-charging. The battery charging system includes a battery composed of one or more re-chargeable cells, a battery charging circuit that controls a charging waveform supplied to the battery, and a detection circuit that detects a decrease in resistance of the battery at an AC signal frequency greater than or equal to 200 Hz. The battery charging circuit controls the charging waveform responsive to an output of the detection circuit. In another battery charging system, the battery has multiple re-chargeable cells. The charging circuit apportions charging waveforms at the cells, and the detection circuit that detects a decrease in resistance of a cell at the AC signal frequency. The battery charging circuit and balancing circuit controls apportioning of the individual charging waveforms responsive to an output of the detection circuit.
    Type: Application
    Filed: February 6, 2024
    Publication date: August 7, 2025
    Inventors: Markos Koseoglou, Emmanuel A. Marchais, Jon D. Hendrix, John L. Melanson
  • Publication number: 20250253888
    Abstract: Self-optimization of an ultra-wideband (UWB) network is performed. A configuration of UWB anchors of a vehicle is identified. A state vector is constructed based on the identified configuration, the state vector including values for status and ranging quality indicators for each of the UWB anchors. A next state is predicted based on the state vector using reinforcement learning to optimize UWB coverage, wherein a conditional probability of the next state depends only on the state vector. Unified configuration interface (UCI) commands are sent to the UWB anchors to reconfigure the UWB anchors based on the predicted next state.
    Type: Application
    Filed: February 7, 2024
    Publication date: August 7, 2025
    Inventors: Jean de Dieu Mutangana, Ivan Vukovic, Nicholas Alexander Scheufler, Sathyanarayana Chary Palakonda, John Eric Rollinger
  • Publication number: 20250252249
    Abstract: Documents are often generated using a customer communication management (CCM) application that utilizes rules to select and/or modify certain fragments of a document. By analyzing the rules and content that produced a certain fragment, a second CCM application may be automatically provided with the rules, such as when the first set of rules are not available for porting to a second system. Accordingly, a server may access a rule comprising a condition, a document fragment, and a rule identifier. A server may generate a first document to comprise visible content and hidden content. Generating the first document may comprise evaluating the rule and, when the rule is true, including the document fragment as a portion of the visible content and including the rule identifier as a portion of hidden content. A server may provide the first document to a destination.
    Type: Application
    Filed: April 25, 2025
    Publication date: August 7, 2025
    Applicant: MICRO FOCUS LLC
    Inventors: Paritosh Tomar, Amit Narang, Anthony John Wiley