Patents by Inventor John Rathmacher

John Rathmacher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods of use of beta-hydroxy-beta-methylbutyrate (HMB) for decreasing fat mass
    Patent number: 10772856
    Abstract: The present invention provides a composition comprising HMB. Methods of administering HMB to an animal are also described. HMB is administered to enhance or promote lipolysis, increase adipocyte fat oxidation, induce adipocyte and muscle mitochondrial biogenesis, increase energy expenditure, decrease total body weight and increase body fat loss.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: September 15, 2020
    Assignee: Metabolic Technologies, Inc.
    Inventors: John Rathmacher, Naji Abumrad, Shawn Baier
  • COMPOSITIONS AND METHODS OF USE OF BETA-HYDROXY-BETA-METHYLBUTYRATE (HMB) AND PROBIOTICS
    Publication number: 20200276143
    Abstract: The present invention provides a composition comprising HMB and at least one probiotic. Methods of administering HMB and at least one probiotic to an animal are also described. HMB and probiotics are administered to attenuate inflammatory cytokine markers and/or maintain muscle integrity.
    Type: Application
    Filed: May 18, 2020
    Publication date: September 3, 2020
    Inventors: Jay Hoffman, John Rathmacher
  • Nutritional intervention for improving muscular function and strength
    Patent number: 10682363
    Abstract: The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: June 16, 2020
    Assignee: Metabolic Technologies, Inc.
    Inventors: John Rathmacher, John Fuller, Jr., Shawn Baier, Steve Nissen, Naji Abumrad
  • Composition of HMB and ATP and Methods of Use
    Publication number: 20200108090
    Abstract: The present invention provides a composition comprising HMB and ATP. Methods of administering HMB and ATP to an animal are also described. HMB and ATP are administered to increase power and strength. The combination of HMB and ATP together has a synergistic effect, which results in a surprising and unexpected level of improvement in power and strength. HMB and ATP are also administered to increase lean body mass and muscle hypertrophy and to prevent typical declines in performance that are characteristic of overreaching.
    Type: Application
    Filed: October 8, 2018
    Publication date: April 9, 2020
    Inventors: Shawn Baier, Larry Kolb, John Rathmacher
  • STABILITY OF VITAMIN D IN BETA-HYDROXY- BETA-METHYLBUTYRATE (HMB)
    Publication number: 20190388372
    Abstract: The present invention provides a composition comprising an acidic formulation containing ?-hydroxy-?-methylbutyrate (HMB), preferably in the free acid form, Vitamin D and a stabilizing excipient, wherein the Vitamin D is stabilized against degradation.
    Type: Application
    Filed: June 25, 2019
    Publication date: December 26, 2019
    Inventors: John Rathmacher, Martin Purpura
  • COMPOSITIONS AND METHODS OF USE OF BETA-HYDROXY-BETA-METHYLBUTYRATE (HMB) ASSOSIATED WITH INTERMITTENT FASTING
    Publication number: 20190209501
    Abstract: The present invention provides a composition comprising HMB and methods of using HMB to mitigate loss of lean body mass, increase fat free mass, improve muscular performance, increase body fat loss and decrease body fat percentage in individuals undergoing intermittent fasting.
    Type: Application
    Filed: January 4, 2019
    Publication date: July 11, 2019
    Inventors: Grant Tinsley, M., John Rathmacher, Lisa Pitchford
  • NUTRITIONAL INTERVENTION FOR IMPROVING MUSCULAR FUNCTION AND STRENGTH
    Publication number: 20190209588
    Abstract: The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
    Type: Application
    Filed: December 21, 2018
    Publication date: July 11, 2019
    Inventors: John Rathmacher, John Fuller, JR., Shawn Baier, Steve Nissen, Naji Abumrad
  • Compositions and Methods of Use of Beta-Hydroxy-Beta-Methylbutyrate (HMB) FOR MODULATING AUTOPHAGY AND LIPOPHAGY
    Publication number: 20190183822
    Abstract: The present invention provides a composition comprising HMB. Methods of administering HMB to an animal are also described. HMB is administered to modulate autophagy and lipophagy. HMB is also administered to treat, prevent, inhibit, slow or reduce autophagy-mediated conditions or diseases.
    Type: Application
    Filed: February 25, 2019
    Publication date: June 20, 2019
    Inventors: Naji Abumrad, John Rathmacher, Shawn Baier
  • COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDHEYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING FIBROSIS OF THE LIVER
    Publication number: 20190099387
    Abstract: Methods and compositions for use in treating, attenuating, preventing or improving liver fibrosis in a subject are described. The compounds of the present invention are gamma-ketoaldehyde scavengers.
    Type: Application
    Filed: September 5, 2018
    Publication date: April 4, 2019
    Inventors: John Rathmacher, Naji Abumrad, Charles Flynn
  • Compositions and methods of use of ?-hydroxy-?-methylbutyrate (HMB) for modulating autophagy and lipophagy
    Patent number: 10213399
    Abstract: The present invention provides a composition comprising HMB. Methods of administering HMB to an animal are also described. HMB is administered to modulate autophagy and lipophagy. HMB is also administered to treat, prevent, inhibit, slow or reduce autophagy-mediated conditions or diseases.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: February 26, 2019
    Assignee: Metabolic Technologies, Inc.
    Inventors: Naji Abumrad, John Rathmacher, Shawn Baier
  • Nutritional intervention for improving muscular function and strength
    Patent number: 10201551
    Abstract: The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: February 12, 2019
    Assignee: Metabolic Technologies, Inc.
    Inventors: John Rathmacher, John Fuller, Jr., Shawn Baier, Steve Nissen, Naji Abumrad
  • Composition of HMB and ATP and methods of use
    Patent number: 10092590
    Abstract: The present invention provides a composition comprising HMB and ATP. Methods of administering HMB and ATP to an animal are also described. HMB and ATP are administered to increase power and strength. The combination of HMB and ATP together has a synergistic effect, which results in a surprising and unexpected level of improvement in power and strength. HMB and ATP are also administered to increase lean body mass and muscle hypertrophy and to prevent typical declines in performance that are characteristic of overreaching.
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: October 9, 2018
    Assignee: Metabolic Technologies, Inc.
    Inventors: Shawn Baier, Larry Kolb, John Rathmacher
  • COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDEHYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING NONALCOHOLIC FATTY LIVER DISEASE (NAFLD), NASH, ALD OR CONDITIONS RELATED TO THE LIVER
    Publication number: 20180153827
    Abstract: Methods and compositions for use in treating, preventing or improving diseases related to the liver in an animal, including but not limited to nonalcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD) or nonalcoholic steatohepatitis (NASH), are described. The compounds of the present invention are gamma-ketoaldehyde scavengers.
    Type: Application
    Filed: September 6, 2017
    Publication date: June 7, 2018
    Inventors: John Rathmacher, Naji Abumrad, Charles Flynn
  • COMPOSITIONS AND METHODS OF USE OF BETA-HYDROXY-BETA-METHYLBUTYRATE (HMB) AND PROBIOTICS
    Publication number: 20180110745
    Abstract: The present invention provides a composition comprising HMB and at least one probiotic. Methods of administering HMB and at least one probiotic to an animal are also described. HMB and probiotics are administered to attenuate inflammatory cytokine markers and/or maintain muscle integrity.
    Type: Application
    Filed: October 20, 2017
    Publication date: April 26, 2018
    Inventors: Jay Hoffman, John Rathmacher
  • Compositions and Methods of Use of beta-hydroxy-beta-methylbutyrate (HMB) for Decreasing Fat Mass
    Publication number: 20180098951
    Abstract: The present invention provides a composition comprising HMB. Methods of administering HMB to an animal are also described. HMB is administered to enhance or promote lipolysis, increase adipocyte fat oxidation, induce adipocyte and muscle mitochondrial biogenesis, increase energy expenditure, decrease total body weight and increase body fat loss.
    Type: Application
    Filed: December 13, 2017
    Publication date: April 12, 2018
    Inventors: John Rathmacher, Naji Abumrad, Shawn Baier
  • NUTRITIONAL INTERVENTION FOR IMPROVING MUSCULAR FUNCTION AND STRENGTH
    Publication number: 20180021353
    Abstract: The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
    Type: Application
    Filed: July 13, 2017
    Publication date: January 25, 2018
    Inventors: John Rathmacher, John Fuller, JR., Shawn Baier, Steve Nissen, Naji Abumrad
  • Nutritional intervention for improving muscular function and strength
    Patent number: 9770424
    Abstract: The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
    Type: Grant
    Filed: January 13, 2016
    Date of Patent: September 26, 2017
    Assignee: Metabolic Technologies, Inc.
    Inventors: John Rathmacher, John Fuller, Jr., Shawn Baier, Steve Nissen, Naji Abumrad
  • Compositions and Methods of Use of Beta-Hydroxy-Beta-Methylbutyrate (HMB) for Modulating Autophagy and Lipophagy
    Publication number: 20170209397
    Abstract: The present invention provides a composition comprising HMB. Methods of administering HMB to an animal are also described. HMB is administered to modulate autophagy and lipophagy. HMB is also administered to treat, prevent, inhibit, slow or reduce autophagy-mediated conditions or diseases.
    Type: Application
    Filed: January 20, 2017
    Publication date: July 27, 2017
    Inventors: Naji Abumrad, John Rathmacher, Shawn Baier
  • Nutritional intervention for improving muscular function and strength
    Patent number: 9707241
    Abstract: The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: July 18, 2017
    Assignee: Metabolic Technologies, Inc.
    Inventors: John Rathmacher, John Fuller, Jr., Shawn Baier, Steve Nissen, Naji Abumrad
  • COMPOSITIONS AND METHODS OF USE OF BETA-HYDROXY-BETA-METHYLBUTYRATE (HMB) FOR JOINT STABILITY
    Publication number: 20170196824
    Abstract: The present invention provides a composition comprising HMB. Methods of administering HMB to an animal are also described. HMB is administered to decrease joint instability, increase joint stability, decrease joint stiffness, improve joint function, improve joint health, improve balanced movement and improve skeletal joint stability during muscle movement. HMB is administered to increase muscle strength and/or muscle mass in a side of the body contralateral to joint inflammation, joint damage, and/or joint injury.
    Type: Application
    Filed: January 13, 2017
    Publication date: July 13, 2017
    Inventors: John Fuller, JR., John Rathmacher, Emily Harris, Shawn Baier