Abstract: Described herein is a capacity system that predicts capacity needs of a system. The capacity system captures outputs from meters coupled to subsystems within the system, where the outputs are not expressed in standard power units. For each subsystem, the capacity system determines values for a set of conversion factors related to the subsystem. The conversion factors describe the design and operation of the subsystem. The capacity system converts the outputs to standard power units based on the set of conversion factors and simulates behavior of the subsystems based on trends shown by the converted outputs. The capacity system forecasts an expected capacity of the system over a time period and uses the forecast to predict a date during the time period when the subsystem will experience a reduction in capacity.

Abstract: A system and method for implementing a cap closure for a carbonated beverage is disclosed. According to one embodiment, an apparatus includes a cap liner having an outer lip and an inner portion. The cap liner is symmetric about a central plane of the inner portion. The outer lip includes an outer nub extending radially outward.

Abstract: The present invention relates to methods of improving body composition and reducing body fat percentage in an individual. The present invention relates to methods comprising administering to an individual a Bacillus subtilis composition wherein the individual's body fat percentage is reduced.

Abstract: The present invention is directed to novel nucleotide and amino acid sequences of Porcine Epidemic Diarrhea Virus (“PEDV”), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine PEDV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include polynucleotide constructs that replicate in tissue culture and in host swine. The invention also provides for novel full length PEDV genomes that can replicate efficiently in host animals and tissue culture.

Abstract: A system and method for using unrecoverable energy in a battery cell is disclosed in this application. A system includes a battery cell, the battery cell includes an excess amount of cathode or anode that can function as half cells in an emergency. A user, such as a pilot, can command a controller to utilize unrecoverable energy based on battery data presented to the user.

Abstract: In one aspect, the invention provides methods for treating, inhibiting, alleviating or preventing fibrosis in a mammalian subject suffering, or at risk of developing a disease or disorder caused or exacerbated by fibrosis and/or inflammation. In one embodiment, the invention provides methods of treating a subject suffering from renal fibrosis. In one embodiment, the invention provides methods of reducing proteinuria in a subject suffering from a renal disease or condition associated with proteinuria. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation.

Abstract: Engineered nucleases are promising tools for genome manipulation and determining off-target cleavage sites of these enzymes is of great interest. This disclosure provides in vitro selection methods that interrogate 1011 DNA sequences for their ability to be cleaved by active nucleases, e.g., ZFNs and TALENs. The method revealed hundreds of thousands of DNA sequences that can be cleaved in vitro by two ZFNs, CCR5-224 and VF2468, which target the endogenous human CCR5 and VEGF-A genes, respectively. Analysis of the identified sites in cultured human cells revealed CCR5-224-induced mutagenesis at nine off-target loci. This disclosure provides an energy compensation model of ZFN specificity in which excess binding energy contributes to off-target ZFN cleavage. It was also observed that TALENs can achieve cleavage specificity similar to or higher than that observed in ZFNs.

Abstract: A respiratory treatment apparatus provides respiratory treatment with improved power management control to permit more efficient power consumption and power supply units, such as battery powered operation. In one embodiment, power management prioritizes the flow generator (104) over other accessories such as the heating elements (111, 135) of a humidifier (112) and/or a delivery tube. The flow generator may control operations of the heating elements as a function of a detected respiratory cycle. For example, the timing of operation of the heating elements may be interleaved with the portion of an inspiratory phase of the respiratory cycle to permit the flow generator to operate during a peak power operation without a power drain or with a lower power drain from these components. Operations of distinct sets of components of the system (e.g., different heating elements) may also be interleaved to prevent simultaneous peak power operations.

Abstract: The present disclosure encompasses engineered meganucleases that bind and cleave recognition sequences within a dystrophin gene. The present disclosure also encompasses methods of using such engineered meganucleases to make genetically modified cells. Further, the disclosure encompasses pharmaceutical compositions comprising engineered meganuclease proteins, or polynucleotides encoding engineered meganucleases of the disclosure, and the use of such compositions for the modification of a dystrophin gene in a subject, or for treatment of Duchenne Muscular Dystrophy.

Abstract: The present invention relates to a method of forming a surface covering for example wallpaper or a floor covering and an apparatus for forming a surface covering, in which a surface covering raw material is supplied, the surface covering raw material comprising a substrate and a resin layer comprising a resin and a carrier liquid, the resin being dispersed in the carrier liquid and being capable of gelling or curing with the carrier liquid. A pattern is then applied to the resin layer by inkjet printing, and the surface covering raw material with the pattern formed on the resin layer is heated to gel or cure the resin layer to thereby prepare a surface covering.

Abstract: Disclosed are sulfur-containing molybdenum complexes used in compositions and methods for inhibiting or reducing high temperature corrosion in petroleum refineries.

Abstract: A modular hub cover which includes a removable hub cover ring having a plurality of hub cover ring openings located around a periphery of the removable hub cover ring, a removable barrel having a first end and a second end, wherein the first end of the removable barrel is operatively attached to the removable hub cover ring, a removable insert located within the removable hub cover barrel and located adjacent to the second end of the removable barrel, and a retaining ring located within the removable hub cover barrel and located adjacent to the billet insert in order to retain the insert within the removable barrel.

Abstract: An example test socket for a test system includes a receptacle to make electrical and mechanical connections to a device under test (DUT) and a lid to cover the DUT in the receptacle. The lid is controllable to open automatically to enable receipt of the DUT in the receptacle and, following receipt of the DUT, to close automatically to cover the DUT in the receptacle. Closing the lid applies force to the DUT to complete the electrical and mechanical connections between the test socket and the DUT.

Abstract: A shock absorber including: a first cylinder having an interior, first and second ends and defining an axis, wherein the interior includes a damping fluid chamber and a damping piston movably mounted therein for movement between the first and second ends, wherein the damping piston is mounted on a first end of a shaft, wherein the first end of the shaft is movably retained within the interior of the first cylinder; first and second bypass openings configured for opening into the damping fluid chamber at first and second axially spaced-apart positions; a bypass channel fluidly coupling the first and second bypass openings; a fluid metering valve; and a floating piston dividing a portion of the shock absorber into a gas chamber and the reservoir chamber, wherein the fluid metering valve and the floating piston define the reservoir chamber there between.

Abstract: The present invention includes systems and methods for a continuous-wave (CW) radar system for detecting, geolocating, identifying, discriminating between, and mapping ferrous and non-ferrous metals in brackish and saltwater environments. The CW radar system generates multiple extremely low frequency (ELF) electromagnetic waves simultaneously and uses said waves to detect, locate, and classify objects of interest. These objects include all types of ferrous and non-ferrous metals, as well as changing material boundary layers (e.g., soil to water, sand to mud, rock to organic materials, water to air, etc.). The CW radar system is operable to detect objects of interest in near real time.

Abstract: Various illustrative systems, devices, and methods of beverage carbonation system flow control are provided. A carbonation system is one example of a treatment system to which the systems, devices, and methods described herein apply. In general, a carbonation system is configured to form a carbonated fluid and dispense the carbonated fluid in a controlled manner. In an illustrative embodiment, the carbonation system is configured to begin dispensing the carbonated fluid with a pressure in a chamber of the carbonation system, in which the carbonated fluid is formed, being above atmospheric pressure. A gas is introduced into the chamber after dispensing has already started via the pressure in the chamber to drive the flow of the carbonated fluid. The gas can be introduced into the chamber according to a predetermined pressure profile.

Abstract: A method is provided for controlling a self-propelled work vehicle comprising a work attachment and at least left and right ground engaging units driven by respective first and second drivetrains. Upon determining transition from a first operating mode to a second operating mode (e.g., creep mode), the method includes selectively derating at least a portion of the drivetrain speed commands corresponding to propulsion of the work vehicle (e.g., the average of left and right track speeds), independent of a portion of the drivetrain speed commands corresponding to steering (e.g., the difference between the track speeds). The derate value may optionally be applied only to propulsion commands that produce forward motion, and not for reverse motion. Separate (non-zero) derate settings may optionally be provided for reverse and/or steering functions. Derate functionality may optionally be implemented upon detecting particular types (e.g. dozer) of attachments, or an associated work state.

Abstract: Systems and assemblies for performing point-of-care, fluidic assays having self-contained, portable fluidic assay systems or assemblies. A housing comprises an assaying assembly, an inspiration actuator, and an expulsion actuator. The inspiration and expulsion actuators may include one-way valves. The assaying assembly is configured to provide a visual indicator in response to being contacted by one or more target analytes within a fluid-assay sample mixture. The fluidic assay assembly has a reciprocal plunger disposed therewithin and, in some embodiments, the plunger has a resilient member to bias the plunger in one direction. Movement of the plunger in a first direction implements an inspiration stroke for drawing the assay sample such that it contacts the fluid from the fluid chamber and continued movement of the plunger implements an expulsion stroke for expelling the fluid-assay sample mixture through the outlet opening to the receptacle of the assaying assembly.

Abstract: Multi-layer coatings comprising polymerization reaction products of 1,1-di-activated vinyl compounds are described. Also provided are processes for coating substrates with curable compositions comprising 1,1-di-activated vinyl compounds. Also provided are articles coated with this composition.