Abstract: A medical device is for applying a force to the body of a subject by means of a force application surface. A material structure has an input for receiving a manual input force from a user of the medical device, and an output coupled to the force application surface for delivering an output force. The material structure implements a force transfer function which includes a force limiting function, so that a limited known force is applied to the body of the subject.

Abstract: According to an aspect, there is provided a cardiopulmonary resuscitation, CPR, device (1) for enhancing the delivery of CPR to a patient. The device (1) comprises: a patient side (3) for engagement with the chest of the patient; and a user side (2) for engagement with the hands of a user delivering CPR to the patient; and an actuator configured to at least partially alter the external form of one or more of the patient side (3) and the user side (2) so as to regulate a shape profile of the one or more of the patient side (3) and the user side (2). According to other aspects, there is provided a control method for a cardiopulmonary resuscitation, CPR, device and a computer program which, when executed on a computing device, carries out a control method for a cardiopulmonary resuscitation, CPR, device.

Abstract: A computer-implemented method for generating feedback based on a handwritten text, comprises the steps of initializing a writing instrument to be used in a writing operation comprising a handwritten text and capturing and processing the handwritten text to generate digital text data. The method further comprises the steps of identifying at least one handwritten text attribute associated with the digital text data, comparing the at least one handwritten text attribute with predefined textual feature attributes, and generating a textual feature based on the compared at least one handwritten text attribute and predefined textual feature attributes. In addition, the method comprises the steps of modifying the digital text data using the textual feature and generating feedback to a user based on the modified digital text data.

Abstract: A method of identifying of amino-acid residues on a target protein that form a binding site of a molecule of interest. Such method relies on selection of relevant patches of solvent-accessible residues and testing of an array of mutated proteins for changes of binding properties. Such method is useful for determining binding sites (epitopes) of antibodies, ligands and related molecules.

Abstract: Technologies disclosed herein are directed to context-based mobile device management. According to one embodiment, an application executing in a mobile device detects an event to trigger context-based management of the mobile device. A usage context associated with the mobile device is determined. One or more policies to enforce on the mobile device are identified as a function of the usage context. The application enforces the one or more policies on the mobile device.

Abstract: Technologies disclosed herein are directed to context-based mobile device management. According to one embodiment, an application executing in a mobile device detects an event to trigger context-based management of the mobile device. A usage context associated with the mobile device is determined. One or more policies to enforce on the mobile device are identified as a function of the usage context. The application enforces the one or more policies on the mobile device.

Abstract: The invention relates to a device for controlling a plurality of nuclear reactors in clusters, comprising, for each reactor, a plurality of sensors for measuring operating parameters as well as a system for controlling the nuclear reactor, the nuclear reactors being grouped into clusters having a cluster head.

Abstract: The present invention relates to a computer-implemented method for administering a cognitive state cue to a user of a cognitive task system, comprising obtaining cognitive task data while the user performs a cognitive task; determining the cognitive state cue based on the cognitive task data, thereby generating a cognitive state cue instruction; executing the cognitive state cue instruction, thereby administering the cognitive state cue to the user. The present invention further relates to a cognitive task system for administering a cognitive state cue to a user of the cognitive task system, comprising: a cognitive task data system configured to obtain cognitive task data while the user performs a cognitive task; a cognitive cue delivery system configured to execute a cognitive state cue instruction; wherein the cognitive state cue instruction is generated by determining the cognitive state cue to be administered to the user based on the cognitive task data.

Abstract: Systems and methods for adjusting bone cut positioning are disclosed that can aid in optimizing implant size selection and positioning relative to bone during, e.g., orthopedic surgical procedures such as knee arthroplasty, hip arthroplasty, etc. In one embodiment, such a surgical method can include performing a first bone cut of a first bone using an at least partially robot-assisted surgical instrument, detecting one or more parameters related to bone hardness, selecting a bone hardness index based on the one or more detected parameters, and adjusting a position of a second bone cut of the first bone based on the selected bone hardness index to optimize implant fit relative to bone. Detecting the one or more parameters related to bone hardness can be performed in a number of manners, including by monitoring energy required to perform the first bone cut.

Abstract: An underwater sound generation device may be used for effective control of algae and other microorganisms in ponds and lakes. The sound projector may comprise a thermoacoustic sound transducer and an electronic unit for controlling the operation of the projector. The thermoacoustic projector may include a freestanding carbon nanotube (CNT) film encapsulated between two vibrating plates. The inert gas filled thin acoustical cavity provides a piston-type displacement of the plates and supports a high-temperature operation. A power supply driver, controlling the operation of the sound radiating system, may include a pulse generator, high-power switch amplifier, and a cable, connecting the projector with an electronic driver. The sound control system may provide an omnidirectional sound pressure level in a wide frequency range to affect the algae growth ecosystem over large distances.

Abstract: The present disclosure relates to antibody molecules comprising a binding domain specific to CD22, said binding domain comprising SEQ ID NO: 1, 2, 3, 4, 5 and 6 or 7. The disclosure also extends to pharmaceutical compositions comprising said antibody molecules and use of the antibody molecules/compositions in treatment.

Abstract: According to an aspect, there is provided a cardiopulmonary resuscitation, CPR, device (1) for enhancing the delivery of CPR to a patient. The device (1) comprises: a patient side (3) for engagement with the chest of the patient; and a user side (2) for engagement with the hands of a user delivering CPR to the patient. One or more of the patient side (3) and the user side (2) is at least partially formed of a non-Newtonian fluid, the viscosity of which is configured to vary in response to the application of energy so as to regulate a force distribution profile of the device (1) from a force applied to the device (1) by the user and transferred through the device (1) to the patient. According to other aspects, there is provided a control method for a cardiopulmonary resuscitation, CPR, device and a computer program which, when executed on a computing device, carries out a control method for a cardiopulmonary resuscitation, CPR, device.

Abstract: Systems, methods, and devices are disclosed for holding devices for securing a surgical robotic device and a patient anatomy positioner to a support (e.g., in an operating room). A holding device comprises a carriage, an anchor component fixed to the carriage for attaching to the support, a patient stabilization connector extending from the anchor component for attaching to the patient positioner, and an elongate holder slidably mounted on the carriage for attaching to the robotic device, wherein, when the anchor component is attached to the support, the carriage and the patient stabilization connector are immobilized. The holding devices may also include a hydraulic cylinder interposed between the elongate holder and carriage and/or a horizontal linkage interposed between the elongate holder and the robotic device.

Abstract: Described herein are concepts, system and techniques which provide a means to construct robust high-field superconducting magnets using simple fabrication techniques and modular components that scale well toward commercialization. The resulting magnet assembly—which utilizes non-insulated, high temperature superconducting tapes (HTS) and provides for optimized coolant pathways—is inherently strong structurally, which enables maximum utilization of the high magnetic fields available with HTS technology. In addition, the concepts described herein provide for control of quench-induced current distributions within the tape stack and surrounding superstructure to safely dissipate quench energy, while at the same time obtaining acceptable magnet charge time. The net result is a structurally and thermally robust, high-field magnet assembly that is passively protected against quench fault conditions.

Abstract: The present disclosure relates to antibody molecules comprising a binding domain specific to CD22, said binding domain comprising SEQ ID NO: 1, 2, 3, 4, 5 and 6 or 7. The disclosure also extends to pharmaceutical compositions comprising said antibody molecules and use of the antibody molecules/compositions in treatment.

Abstract: A provider computing system includes an image database structured to store an image relating to a user, an advertisement template database structured to store a plurality of advertisement templates, a tagging circuit structured to augment the image in the image database with one or more image attribute tags and augment each of the plurality of advertisement templates with a template attribute tag, a customization circuit coupled to the tagging circuit, the customization circuit structured to determine a match between the image and a first advertisement template of the plurality of advertisement templates based on the image attribute tags and the template attribute tags for the first advertisement template and integrate the image into the first advertisement template to generate a customized advertisement, and an advertisement selection circuit structured to cause the customized advertisement to be provided to the user.

Abstract: A computer-implemented method for designing a user-specific writing skill game is provided. The computer-implemented method comprises tracking a handwriting performance and generating a digital representation of the handwriting performance. The handwriting performance is performed by a user with a writing instrument. The method further comprises identifying user-specific handwriting skills which require improvement based on the digital representation of the handwriting performance. Then a writing skill game is designed. The writing skill game is designed to include one or more game tasks to be performed by the user. The one or more game tasks require the user to apply the user-specific handwriting skills which are to be improved.

Abstract: Introduced here are approaches to transferring relevant information from a first electronic device (also called a “source electronic device”) that is presently outputting an interfacing signal that is detectable by a second electronic device (also called a “recipient electronic device”) via modification of the interfacing signal. Such modification causes the relevant information to be appended to the interfacing signal and then transferred to the recipient electronic device. This can be accomplished by superimposing another signal that is representative of the relevant information onto the interfacing signal. Thus, the relevant information can be transferred from the source electronic device to the recipient electronic device by superimposing a signal onto the interfacing signal that is output by the source electronic device.

Abstract: A computer-implemented method (100) for generating feedback based on a handwritten text, comprises the steps of initializing (110) a writing instrument (10) to be used in a writing operation comprising a handwritten text and capturing and processing (120) the handwritten text to generate digital text data. The method further comprises the steps of identifying (130) at least one handwritten text attribute associated with the digital text data, comparing (140) the at least one handwritten text attribute with predefined textual feature attributes, and generating (150) a textual feature based on the compared at least one handwritten text attribute and predefined textual feature attributes. In addition, the method comprises the steps of modifying (160) the digital text data using the textual feature and generating (170) feedback to a user (U) based on the modified digital text data.