Patents by Inventor Jonathan Braun

Jonathan Braun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100267037
    Abstract: The invention provides a method for detection of inflammatory disease in a subject that comprises assaying a test sample of peripheral blood from the subject for a marker of DNA damage. An elevated amount of marker present in the test sample compared to control sample is indicative of inflammatory disease activity, including sub-clinical inflammation. The method can be adapted for quantitatively monitoring the efficacy of treatment of inflammatory disease in a subject. Markers of DNA damage include single- and/or double-stranded breaks in leukocytes, oxidative DNA damage in leukocytes, or a marker of nitric oxide oxidative activity (protein nitrosylation in leukocytes). The inflammatory disease can be inflammatory bowel disease (ulcerative colitis or Crohn's disease).
    Type: Application
    Filed: April 15, 2010
    Publication date: October 21, 2010
    Applicant: The Regents of the University of California
    Inventors: Aya M. Westbrook, Robert H. Schiestl, Bo Wei, Jonathan Braun
  • Publication number: 20100196509
    Abstract: The present invention discloses methods of using endothelial membrane protein 2 (EMP2) as a biomarker for stratification of endometrial premalignancy, diagnosing, staging and imaging of endometrial neoplasia. Further, methods for identifying pharmaceutical/therapeutic modalities are described, including compositions which modulate glycolipid-enriched lipid raft microdomains (GEMs).
    Type: Application
    Filed: February 28, 2006
    Publication date: August 5, 2010
    Inventors: Jonathan Braun, Madhuri Wadehra, Sathima Natarajan, Robert Soslow
  • Publication number: 20090286477
    Abstract: Methods, portable electronic devices, systems and computer program products for wirelessly transmitting information from an electronic whiteboard. A wireless connection is established between a portable electronic device and the electronic whiteboard. A digital copy of content of the electronic whiteboard is received at the portable electronic device over the established wireless connection.
    Type: Application
    Filed: May 15, 2008
    Publication date: November 19, 2009
    Inventor: Andrew Jonathan Braun
  • Publication number: 20090287928
    Abstract: Methods, portable electronic devices, systems and computer program products for securing an electronic whiteboard. A near field communication (NFC) session is established between a portable electronic device and the electronic whiteboard to secure information provided on the electronic whiteboard. Dispersion of the information provided on the electronic whiteboard is enabled and/or disabled using security credentials associated with the established NFC session.
    Type: Application
    Filed: May 15, 2008
    Publication date: November 19, 2009
    Inventor: Andrew Jonathan Braun
  • Publication number: 20090221006
    Abstract: The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence or IgA anti-OmpC antibodies in the subject, where the presence of the IgA anti-OmpC antibodies indicates that the subject has Crohn's disease.
    Type: Application
    Filed: January 12, 2009
    Publication date: September 3, 2009
    Applicants: Cedars-Sinai Medical, The Regents of the University of California
    Inventors: Stephan R. Targan, Jonathan Braun, Christopher L. Sutton
  • Publication number: 20090221007
    Abstract: The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence or IgA anti-OmpC antibodies in the subject, where the presence of the IgA anti-OmpC antibodies indicates that the subject has Crohn's disease.
    Type: Application
    Filed: January 12, 2009
    Publication date: September 3, 2009
    Applicants: Cedars-Sinai Medical Center, The Regents of the University of California
    Inventors: Stephan R. Targan, Jonathan Braun, Christopher L. Sutton
  • Patent number: 7557194
    Abstract: The present invention provides nucleic acid and amino acid sequence of the novel I-1 and I-2 polypeptides, which are associated with human inflammatory bowel disease (IBD). Methods of diagnosing and treating inflammatory bowel disease using the IBD-associated I-1 and I-2 antigens also are provided.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: July 7, 2009
    Assignee: The Regents of the University of California
    Inventors: Jonathan Braun, Christopher Sutton
  • Publication number: 20090017749
    Abstract: According to teachings presented herein, a system and method enhance live events by providing coordinated content delivery to mobile device subscribers physically present at the live event. As a non-limiting example, a system is configured to feed any one or more of replay video, alternate or zoom camera angles, and supporting information for the event, such as interesting data on event participants, e.g., player statistics, etc. Accordingly, one embodiment of a method of delivering location-based event content to a mobile station comprises determining that the mobile station is physically present at an event venue, identifying desired types of event feeds for the mobile station for a live event at the event venue, and dynamically delivering one or more event feeds of the desired types to the mobile station. A system for supporting the method may be implemented in whole or in part in a cellular communication network.
    Type: Application
    Filed: July 13, 2007
    Publication date: January 15, 2009
    Applicant: SONY ERICSSON MOBILE COMMUNICATIONS AB
    Inventor: Andrew Jonathan Braun
  • Publication number: 20080181889
    Abstract: The present invention provides methods and compositions useful in the treatment or prevention of Chlamydia infections. The methods and compositions inhibit the entry of Chlamydia into a host cell expressing EMP2 by interfering with the interaction between the Chlamydia and EMP2. The compositions include EMP2 nucleic acids and polypeptides as well as anti-EMP2 antibodies.
    Type: Application
    Filed: October 8, 2007
    Publication date: July 31, 2008
    Applicants: The Regents of the University of California, US Government represented by the Department of Veterans Affairs
    Inventors: Jonathan Braun, Lynn K. Gordon, Kaori Shimazaki, Madhuri Wadehra-Dhawan, Kathy A. Kelly
  • Publication number: 20070161065
    Abstract: The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence or IgA anti-OmpC antibodies in the subject, where the presence of the IgA anti-OmpC antibodies indicates that the subject has Crohn's disease.
    Type: Application
    Filed: November 17, 2006
    Publication date: July 12, 2007
    Applicants: Cedars-Sinai Medical Center, The Regents of the University of California
    Inventors: Stephan Targan, Jonathan Braun, Christopher Sutton
  • Patent number: 7183065
    Abstract: The present invention relates to microbial UC pANCA antigens. The invention provides methods of diagnosing ulcerative colitis (UC) and methods of inducing tolerance in a pANCA-positive patient with UC using a histone H1-like antigen. The invention further provides methods of diagnosing UC and methods of inducing tolerance in a pANCA-positive patient with UC using a porin antigen. Methods of diagnosing UC and methods of inducing tolerance in a pANCA-positive patient with UC using a Bacteroides antigen also are provided.
    Type: Grant
    Filed: August 27, 2002
    Date of Patent: February 27, 2007
    Assignee: The Regents of the University of California
    Inventors: Jonathan Braun, Offer Cohavy
  • Patent number: 7138237
    Abstract: The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence of IgA anti-OmpC antibodies in the subject, where the presence of the IgA anti-OmpC antibodies indicates that the subject has Crohn's disease.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: November 21, 2006
    Assignees: Cedars-Sinai Medical Center, The Regents of the University of California
    Inventors: Stephan R. Targan, Jonathan Braun, Christopher L. Sutton
  • Patent number: 6821739
    Abstract: The present invention provides a method of identifying an agent useful in treating Crohn's disease. This method is practiced by culturing P. fluorescens under conditions that support growth; contacting the P. fluorescens with an agent; and assaying for reduced growth or viability of the P. fluorescens as compared to the growth or viability in the absence of the agent, where the reduced growth or viability of the P. fluorescens indicates that the agent is an anti-P. fluorescens agent useful in treating Crohn's disease. Also provided by the invention is a method of preventing or treating Crohn's disease in an individual by administering to the individual an effective dose of an anti-Pseudomonas vaccine.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: November 23, 2004
    Assignee: The Regents of the University of California
    Inventors: Jonathan Braun, Bo Wei, Ashley Forbes
  • Publication number: 20040197871
    Abstract: The present invention provides nucleic acid and amino acid sequence of the novel I-1 and I-2 polypeptides, which are associated with human inflammatory bowel disease (IBD). Methods of diagnosing and treating inflammatory bowel disease using the IBD-associated I-1 and I-2 antigens also are provided.
    Type: Application
    Filed: April 30, 2004
    Publication date: October 7, 2004
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jonathan Braun, Christopher Sutton
  • Patent number: 6759530
    Abstract: The present invention provides nucleic acid and amino acid sequence of the novel I-1 and I-2 polypeptides, which are associated with human inflammatory bowel disease (IBD). Methods of diagnosing and treating inflammatory bowel disease using the IBD-associated I-1 and I-2 antigens also are provided.
    Type: Grant
    Filed: September 27, 2001
    Date of Patent: July 6, 2004
    Assignee: The Regents of the University of California
    Inventors: Jonathan Braun, Christopher Sutton
  • Publication number: 20030092080
    Abstract: The present invention relates to microbial UC pANCA antigens. The invention provides methods of diagnosing ulcerative colitis (UC) and methods of inducing tolerance in a pANCA-positive patient with UC using a histone H1-like antigen. The invention further provides methods of diagnosing UC and methods of inducing tolerance in a pANCA-positive patient with UC using a porin antigen. Methods of diagnosing UC and methods of inducing tolerance in a pANCA-positive patient with UC using a Bacteroides antigen also are provided.
    Type: Application
    Filed: August 27, 2002
    Publication date: May 15, 2003
    Applicant: The Regents of the University of California
    Inventors: Jonathan Braun, Offer Cohavy
  • Patent number: 6537768
    Abstract: The present invention relates to microbial UC pANCA antigens. The invention provides methods of diagnosing ulcerative colitis (UC) and methods of inducing tolerance in a pANCA-positive patient with UC using a histone H1-like antigen. The invention further provides methods of diagnosing UC and methods of inducing tolerance in a pANCA-positive patient with UC using a porin antigen. Methods of diagnosing UC and methods of inducing tolerance in a pANCA-positive patient with UC using a Bacteroides antigen also are provided.
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: March 25, 2003
    Assignee: The Regents of the University of California
    Inventors: Jonathan Braun, Offer Cohavy
  • Publication number: 20020115848
    Abstract: The present invention provides nucleic acid and amino acid sequence of the novel I-1 and I-2 polypeptides, which are associated with human inflammatory bowel disease (IBD). Methods of diagnosing and treating inflammatory bowel disease using the IBD-associated I-1 and I-2 antigens also are provided.
    Type: Application
    Filed: September 27, 2001
    Publication date: August 22, 2002
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jonathan Braun, Christopher L. Sutton
  • Publication number: 20020068313
    Abstract: The present invention provides a method of identifying an agent useful in treating Crohn's disease. This method is practiced by culturing P. fluorescens under conditions that support growth; contacting the P. fluorescens with an agent; and assaying for reduced growth or viability of the P. fluorescens as compared to the growth or viability in the absence of the agent, where the reduced growth or viability of the P. fluorescens indicates that the agent is an anti-P. fluorescens agent useful in treating Crohn's disease. Also provided by the invention is a method of preventing or treating Crohn's disease in an individual by administering to the individual an effective dose of an anti-Pseudomonas vaccine.
    Type: Application
    Filed: October 12, 2001
    Publication date: June 6, 2002
    Inventors: Jonathan Braun, Bo Wei, Ashley Forbes
  • Patent number: 6320037
    Abstract: The present invention provides nucleic acid and amino acid sequence of the novel I-1 and I-2 polypeptides, which are associated with human inflammatory bowel disease (IBD). Methods of diagnosing and treating inflammatory bowel disease using the IBD-associated I-1 and I-2 antigens also are provided.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: November 20, 2001
    Assignee: The Regents of the University of California
    Inventors: Jonathan Braun, Christopher Sutton