Patents by Inventor Jonathan Braun

Jonathan Braun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IBD-associated microbial nucleic acid molecules
    Patent number: 6320037
    Abstract: The present invention provides nucleic acid and amino acid sequence of the novel I-1 and I-2 polypeptides, which are associated with human inflammatory bowel disease (IBD). Methods of diagnosing and treating inflammatory bowel disease using the IBD-associated I-1 and I-2 antigens also are provided.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: November 20, 2001
    Assignee: The Regents of the University of California
    Inventors: Jonathan Braun, Christopher Sutton
  • IBD-associated microbial antigens and methods of using same
    Patent number: 6309643
    Abstract: The present invention provides nucleic acid and amino acid sequence of the novel I-1 and I-2 polypeptides, which are associated with human inflammatory bowel disease (IBD). Methods of diagnosing and treating inflammatory bowel disease using the IBD-associated I-1 and I-2 antigens also are provided.
    Type: Grant
    Filed: April 30, 1999
    Date of Patent: October 30, 2001
    Assignee: The Regents of the University of California
    Inventors: Jonathan Braun, Christopher Sutton
  • IBD-associated microbial nucleic acid molecules
    Publication number: 20010022971
    Abstract: The present invention provides nucleic acid and amino acid sequence of the novel I-1 and I-2 polypeptides, which are associated with human inflammatory bowel disease (IBD). Methods of diagnosing and treating inflammatory bowel disease using the IBD-associated I-1 and I-2 antigens also are provided.
    Type: Application
    Filed: March 28, 2001
    Publication date: September 20, 2001
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA.
    Inventors: Jonathan Braun, Christopher Sutton
  • Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using microbial UC pANCA antigens
    Patent number: 6033864
    Abstract: The present invention relates to microbial UC pANCA antigens. The invention provides methods of diagnosing ulcerative colitis (UC) and methods of inducing tolerance in a pANCA-positive patient with UC using a histone H1-like antigen. The invention further provides methods of diagnosing UC and methods of inducing tolerance in a pANCA-positive patient with UC using a porin antigen. Methods of diagnosing UC and methods of inducing tolerance in a pANCA-positive patient with UC using a Bacteroides antigen also are provided.
    Type: Grant
    Filed: March 12, 1998
    Date of Patent: March 7, 2000
    Assignee: The Regents of the University of California
    Inventors: Jonathan Braun, Offer Cohavy
  • Anti-VH3-15 reagents and methods for their use
    Patent number: 5738847
    Abstract: Anti-VH3-15 idiotypic antibody materials, hybridomas producing this antibody material and methods for using these to detect, isolate and purify VH3-15 polypeptides. Also provided in the present invention are nucleic acid molecules encoding anti-VH3-15 antibody material and methods for using these molecules to detect, isolate and purify VH3-15 nucleic acid sequences.
    Type: Grant
    Filed: September 19, 1994
    Date of Patent: April 14, 1998
    Assignee: The Regents of the University of California
    Inventor: Jonathan Braun
  • Immunoglobulin superantigen binding to gp 120 from HIV
    Patent number: 5691135
    Abstract: VH3 and VH4 type immunoglobulins display superantigen-type binding affinity for the HIV gp120 envelope glycoprotein. VH3 and VH4 type antibody molecules, including IgG and IgM, are shown to suppress HIV infection in vivo and in vitro. Determining the level of such antibody molecules is correlated to the advancement of HIV disease state.
    Type: Grant
    Filed: September 14, 1994
    Date of Patent: November 25, 1997
    Assignee: The Regents of the University of California
    Inventors: Jonathan Braun, Lee A. Goodglick
  • Methods of screening for ulcerative colitis and crohn's disease by detecting VH3-15 autoantibody and panca
    Patent number: 5691151
    Abstract: The present invention provides novel methods of screening for ulcerative colitis and Crohn's disease which include the detection of two disparate autoantibodies: pANCA and VH3-15 autoantibody. The present invention also provides kits for screening ulcerative colitis and Crohn's disease.
    Type: Grant
    Filed: October 7, 1994
    Date of Patent: November 25, 1997
    Assignee: Regents of University of California
    Inventors: Jonathan Braun, Stephan R. Targan