Abstract: An optical display, including a first waveguide having a first set of surfaces, an input grating, a fold grating, and an output grating; an image input image node assembly; and a prismatic relay optics is provided. The prismatic relay optics may be configured to be optomechanically connected to the waveguide and the input image node assembly. The optical display is may also be configured to operate alone or as integrated with a headpiece to be used as a HUD. The HUD may have a first and a second configuration wherein the waveguide is decoupled or coupled.

Abstract: The specification relates to conjugates comprising a linker of Formula (IMA): and pharmaceutically acceptable salts thereof. The specification also relates the use of the conjugates for the treatment of diseases such as cancer, and intermediates useful for the synthesis of the conjugates.

Abstract: Characteristics of a window treatment fabric, a control device, and/or a lighting control system may be simulated for being installed in a space. A graphical representation of the window treatment fabric may be overlaid on an image being displayed on a display of a user device. A graphical representation of the control device may be overlaid on the image being displayed on the user device. A change in color temperature settings over a time of day may be simulated for lighting devices installed in a lighting control system in a space. A color graph may be overlaid on the image displayed on the user device that is configured with different color temperature values at a corresponding time of day and images may be displayed to reflect the corresponding color temperature values.

Abstract: A method for treating a patient via high-frequency (HF) electrostimulation therapy at an external target body location comprises generating a tonic motor activation (TOMAC) electrostimulation waveform using a power source supplying less than 100 volts zero-to-peak voltage amplitude per phase. The waveform has a frequency of 1,000 Hz to 5,000 Hz, a zero-to-peak current amplitude of 10-50 mA, and a duty cycle greater than 25%. The waveform is configured to overcome skin capacitance, induce proprioceptive afferent activity, and induce sustained tonic motor activation of a muscle. The method involves delivering the waveform to the external target body location over a specified duration during the patient's sleep period and receiving at least one TOMAC efficacy indication. The efficacy indication may relate to sleep efficiency, sleep stage, sleep onset latency, daytime sleepiness, CPAP compliance, or patient physiological response indicating TOMAC.

Abstract: The invention relates to an automated hand, such as a prosthetic hand. In one form, the automated hand may be fluid compatible. In one form, the automated hand may comprise features to reduce the risk of harm to motors and/or other sensitive components of the hand when subject to an impact. In one form, the hand may comprise a wrist joint configured to allow the hand to curl and flex and/or to rotate. In one form, one or more digits of the hand may be individually controlled. In one form the hand may include a thumb rotation locking mechanism. In one form the hand may be provided with removable grip plates. In one form, the hand May be configured for use as a training hand.

Abstract: The specification relates to conjugates comprising a linker of Formula (IA): and pharmaceutically acceptable salts thereof. The specification also relates the use of the conjugates for the treatment of diseases such as cancer, and intermediates useful for the synthesis of the conjugates.

Abstract: A locking mechanism for a hold open rod. The hold open rod includes a first elongate member and a second elongate member, slidably arranged to move between a first configuration and a second configuration, the second configuration being extended relative to the first configuration. The mechanism includes a locking mechanism operable between a locked state and an unlocked state and arranged, in the locked state, to prevent the first and second elongate members from returning to the first configuration. The first elongate member includes a first surface. The locking mechanism includes a locking member moveable between a first position and a second position. The locking member includes a second surface.

Abstract: A respiratory mask can include one or a plurality of force sensors configured to detect a force imparted to a user's skin. Output from the one or more sensors can be represented in a way useful to the patient or healthcare provider for adjusting the mask to achieve a desired fitment. A representation of the detected forces can be displayed on a separate display device or on the mask.

Abstract: High flow therapy is used to treat Cheyne-Stokes respiration and other types of periodic respiration disorders by periodic application of high flow therapy, adjustment of high flow therapy flow rates and/or periodic additions of CO2 or O2 into the air flow provided to the patient.

Abstract: This invention relates to a surgical smoke evacuation system for use in removing gases and smoke created in surgical procedures form within an insufflated surgical cavity.

Abstract: A general purpose sensor architecture integrating a surface enhanced Raman spectroscopy (SERS) substrate, a diffractive laser beam delivery substrate and a diffractive infrared detection substrate is provided that can be used to implement a low-cost, compact lab-on-a-chip biosensor that can meet the needs of large-scale infectious disease testing. The sensor architecture can also be used in any other application in which molecules present in the liquid, gaseous or solid phases need to be characterized reliably, cost-effectively and with minimal intervention by highly skilled personnel.

Abstract: Embodiments herein describe combining multiple optical signals so these signals propagate in the same direction in the same optical mode and polarization. In one embodiment, the techniques discussed herein are used to combine a reference laser with a frequency comb so that supercontinuum generation can then be performed to increase the frequency range of the frequency comb so that it includes the frequency of the reference laser.

Abstract: Breathing assistance apparatus includes a gases supply unit adapted to, in use, deliver a stream of pressurised gases from an outlet. The gases supply unit is adapted to vary the pressure of the stream of pressurised gases. A supply path includes a flexible self-supporting gases transportation pathway having a first end connected to the outlet so that the gases transportation pathway receives the stream of gases and conveys the gases to a patient. A patient interface is connected to the second end of the gases transportation pathway receives a stream of gases. At least one sensor measures at least one information parameter of the supply path. A control system associated with the gases supply unit receives the information parameter. The control system contains reference data, and compares the received data to reference data, and determines a supply path based on the comparison.

Abstract: Distribution and management of services in virtual environments is described herein. In one or more implementations, a service distribution and management model is implemented in which system services and applications are seamlessly distributed across multiple containers which each implement a different runtime environment. In one or more implementations, a system for distributing access to services in a host operating system of a computing device includes a host operating system configured to implement a host runtime environment, and one or more services implemented by the host operating system. The system further includes a service control manager configured to enable communication between a client stub of a service implemented in a client runtime environment and a service provider of the service that is implemented in a service runtime environment that is separate from the first client runtime environment.

Abstract: Embodiments, described herein relate generally to devices, systems, apparatus, and methods for producing lubricious surfaces that increase the ease of communication of viscous liquids across the same. The apparatus can include a container having an inner surface and a lubricating liquid disposed on a surface, the lubricating liquid including a surfactant. In some embodiments, a sprayer hub can rotate about a center axis and deliver the lubricating liquid to the inner surface. In some embodiments, a contact liquid can fill at least a portion of the container. In some embodiments, the surfactant can be an amphiphilic molecule that is substantially immiscible with the lubricating liquid and at least partially miscible with the contact liquid. In some embodiments, the surfactant can form a barrier at an interface between the lubricating liquid and the contact liquid.

Abstract: High flow therapy is used to treat Cheyne-Stokes respiration and other types of periodic respiration disorders by periodic application of high flow therapy, adjustment of high flow therapy flow rates and/or periodic additions of CO2 or O2 into the air flow provided to the patient.

Abstract: Embodiments herein describe an ASIC design where certain portions of the laser driver are controllable by the user. In one embodiment, the ASIC may include one or more pins which provide a connection interface where the user can electrically connect a sense resistor that corresponds to the particular laser being used. The remaining portions of the laser driver are implemented in the ASIC, thereby giving the user the flexibility to adapt the laser driver to her selected laser while having the advantages that come from using an ASIC.