Abstract: Compounds of formula (I): wherein R1, R2, R3, R5, R6, A1, A2, A3, A4 assume meanings as defined in formula (I) are inhibitors of neutrophil elastase.

Abstract: An airline operations control system for an airline having multiple aircraft and multiple routes formed by one or more flights, which are implemented by the aircraft flying the flights forming the routes, where the airline operations control system includes a computer searchable database, a query module configured to query the database, and a prognostic module.

Abstract: The present invention relates to physically stable oil dispersions. It also relates to a method for activating bentones that are designed for use with a low polarity organic systems. It also relates to physically stable oil dispersions comprising said activated bentone.

Abstract: A method including (a) providing an amplification reagent including an array of sites, and a solution having different target nucleic acids; and (b) reacting the amplification reagent to produce amplification sites each having a clonal population of amplicons from a target nucleic acid from the solution. The reacting can include simultaneously transporting the nucleic acids to the sites at an average transport rate, and amplifying the nucleic acids that transport to the sites at an average amplification rate, wherein the average amplification rate exceeds the average transport rate. The reacting can include producing a first amplicon from a nucleic acid that transports to each of the sites, and producing subsequent amplicons from the nucleic acid or from the first amplicon, wherein the average rate at which the subsequent amplicons are generated exceeds the average rate at which the first amplicon is generated.

Abstract: The invention provides a method for preparing and analysing a population of fragmented polynucleotide sequences having a substantially uniform size. The method can include steps of (a) binding at least one protection molecule to at least one polynucleotide sequence; (b) cleaving the at least one polynucleotide sequence to generate a plurality of polynucleotide fragment sequences of substantially uniform size; (c) amplifying the polynucleotide fragments; and (d) determining a sequence characteristic of a plurality of the polynucleotide fragments.

Abstract: An apparatus for charging multiple rechargeable devices is disclosed. The apparatus includes a hub or multiple T-connectors connected between a power source, preferably a Zinc-air battery, and several chargers, the hub/T-connectors configured to provide electrical and mechanical connectivity between the power source and the chargers. The apparatus includes housings configured to encase the chargers and to conformally receive each of the corresponding devices containing rechargeable batteries. The apparatus further includes pouches configured to removably receive chargers, devices, and the power source. When the power source voltage falls below a certain threshold, then a charger associated with a device having the smallest difference between its rated voltage and its measured voltage discontinues charging before other chargers. The apparatus is wearable by a user.

Abstract: Patient support apparatuses, such as beds, cots, stretchers, recliners, operating tables, and the like include wireless mesh network transceivers that enable them to communicate with each other, and other devices, via mesh networks and/or ad hoc networks. One or more additional wireless transceivers are included, such as WiFi transceivers, that enable direct communication with a healthcare facility network, such as an Ethernet. The mesh network communication between patient support apparatuses and other devices is used for any one or more of: extending the communication range of the existing IT infrastructure, efficiently routing data to the healthcare facility network, determining location of the patient support apparatuses and devices, transporting patient data from one patient support to the next as the patient moves, and for other aspects.

Abstract: The present technology relates to molecular sciences, such as genomics. More particularly, the present technology relates to nucleic acid sequencing.

Abstract: There is provided a cable breakout support (100), comprising a clamp (200) for clamping to a trunking (110), and a clip (210) for clipping to a cable breakout of a cable bundle (120, 122) supported in the trunking. Each clamp comprises at least two trunk fittings (202) for fitting to at least two respective bulbous longitudinal edges (111, 112) of the trunking; and a clip fitting (205) for connecting to a respective clip.

Abstract: An airline operations control system for an airline having multiple aircraft and multiple routes formed by one or more flights where the airline operations control system includes a computer searchable database a query module configured to query the database and a prognostic module.

Abstract: Improved compositions, methods, apparatus, and kits for high-throughput nucleic acid amplification, detection and sequencing are disclosed. A nucleic acid cluster having an identifiable center is produced by generating on a solid support an immobilized nucleic acid complement from a template, one of which comprises a detectable label; and amplifying the complement and the template to obtain a nucleic acid cluster on the support, the cluster having a substantially central location marked by the detectable label and a surrounding region comprising immobilized copies. Also disclosed are nucleotide sequence determination in nucleic acid clusters so produced, center position annotation in the clusters, assignment of sequence information to overlapping clusters, and related compositions and methods.

Abstract: Disclosed herein are compositions and methods for sequencing nucleic acids.

Abstract: In one embodiment, an X-ray system includes a handheld X-ray interface device. The handheld X-ray interface device includes a wireless interface for communicating with an imaging system and for receiving system operational data from the imaging system, wherein the handheld X-ray interface device is configured to provide a user detectable indication of the imaging system operational status based upon the received data.

Abstract: This invention relates to a breath indicator that is receivable by a part of a breathing assistance apparatus that supplies gas to a patient. The indicator comprises an elongate body having a gas sampling end and an attachment end. The attachment end is adapted to attach to a part of a breathing assistance apparatus and for locating the gas sampling end. The gas sampling end is to be located in a region where gas from the patient is to be exhaled. The gas sampling end being in communication with a sensor comprising a detector material changeable between a first visual indicator state relating to an inhalation phase of the patient, and a second visual indicator state relating to an exhalation phase of the patient. The detector material is capable of changing between the visual indicator states at a sufficient rate to substantially correspond with the inhalation and exhalation phases of the patient.

Abstract: Mobility devices are provided that enable a user to walk when the user's lower leg is in a non-functioning condition. A mobility device includes a main body, a lower leg support, an upper leg support, and a foot. The main body can be secured to a lateral side of the user's upper leg with the upper leg support. The lower leg support is connected to the main body and supports the user's lower leg. The foot is connected to a lower end of the main body and is configured to engage the ground. The foot may have a split foot configuration with a first portion and a second portion. The first portion of the foot is positioned rearward of the main body and the second portion of the foot is positioned forward of the main body. Each of the first and second foot portions may have an arcuately shaped profile.

Abstract: The present invention described and shown in the specification and drawings provides novel recombinant DT-based immunotoxins, and, more specifically anti-T cell immunotoxin fusion proteins. Also provided are immunotoxins that can be ex-pressed in bacterial, yeast, or mammalian cells. The invention also provides means for expression of the immunotoxin fusion protein. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.

Abstract: There is disclosed a connector system (500) comprising a contact pin (400) and a socket (200) for receiving the contact pin. The contact pin comprises a first groove (402) extending around the axis (410) of the contact pin; a coiled spring (404) within the first groove; and a set of teeth (406) extending around the axis of the contact pin. The socket (200) comprises a cup portion (202). The cup portion comprises a set of teeth (206) extending around the axis (210) of the cup portion (202) and for engaging with the teeth (406) of the contact pin; and a first contact surface (518) inside the cup portion and extending around the axis (210) of the cup portion for contacting the coiled spring (404) of the contact pin.

Abstract: A connector (100) for making an electrical connection between two plates (110, 120) that are mechanically secured to one another, the connector comprising a first socket (50) for fixing to a first plate (110), a second socket (60) for fixing to a second plate (120), and a connector pin (150), the first and second sockets both comprising an aperture (55, 65) for receiving the connector pin (150), wherein the connector further comprises a first spring (161) for contacting between the connector pin and the first socket, and a second spring (162) for contacting between the connector pin and the second socket.

Abstract: Mobility devices are provided that enable a user to walk when the user's lower leg is in a non-functioning condition. A mobility device includes a main body, a lower leg support, an upper leg support, and a foot. The main body can be secured to a lateral side of the user's upper leg with the upper leg support. The lower leg support is connected to the main body and supports the user's lower leg. The foot is connected to a lower end of the main body and is configured to engage the ground. The foot may have a split foot configuration with a first portion and a second portion. The first portion of the foot is positioned rearward of the main body and the second portion of the foot is positioned forward of the main body. Each of the first and second foot portions may have an arcuately shaped profile.