Abstract: The present invention provides a method of creating an array of features. The method can include steps of (a) providing a plurality of beads, wherein each bead in the plurality of beads includes probe content; (b) contacting the plurality of beads with a surface to produce a layer of beads on the surface; and (c) transferring the probe content from the beads to the surface to create an array of spatially discrete features on the surface, wherein each spatially discrete feature includes probe content from a bead in the plurality of beads.

Abstract: The invention provides methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template.

Abstract: A system for automatically analysing aircraft systems data is described. The system comprises a data acquisition module operable to acquire aircraft systems data, a data archiving module operable to store aircraft systems data and a data analysis module operable to analyse the aircraft systems data to identify non-predetermined troubleshooting procedures for fault rectification. Automated identification of improved maintenance techniques can thus be provided, with the added benefit that maintenance manuals and procedures may thereby be automatically adapted over time. A related method is also described.

Abstract: An airline operations control system for an airline having multiple aircraft and multiple routes formed by one or more flights where the airline operations control system includes a computer searchable database a query module configured to query the database and a prognostic module.

Abstract: An airline operations control system for an airline having multiple aircraft and multiple routes formed by one or more flights where the airline operations control system includes a computer searchable database a query module configured to query the database and a display module and a method of controlling operation of the airline having the multiple aircraft and the multiple routes.

Abstract: Novel forms of atorvastatin magnesium salt designated Form A, Form B, Form C, Form D, Form E, and Form F, pharmaceutical compositions containing such compounds, methods for their preparation and methods utilizing the compounds for treatment of hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPH) and Alzheimer's disease are described.

Abstract: An apparatus and method for aggregating health management information includes an aircraft having a flight computer coupled to a plurality of aircraft systems. Each system has a built in test (BIT) protocol that self-diagnoses a health of the system and outputs corresponding BIT data to the flight computer for contemporaneous display on a flight display.

Abstract: Methods for amplifying nucleic acids are provided. The methods can be used to minimise sequence specific bias caused by the preferential amplification of certain nucleic acid sequences. Methods are described which can lower the efficiency of AT rich templates relative to GC rich templates, thereby minimising GC bias during amplification reactions with multiple templates of different sequence. The methods are suited to solid phase amplification, for example, utilising flow cells.

Abstract: The present invention provides a method of creating an array of features. The method can include steps of (a) providing a plurality of beads, wherein each bead in the plurality of beads includes probe content; (b) contacting the plurality of beads with a surface to produce a layer of beads on the surface; and (c) transferring the probe content from the beads to the surface to create an array of spatially discrete features on the surface, wherein each spatially discrete feature includes probe content from a bead in the plurality of beads.

Abstract: Compounds of formula (I): are useful as inhibitors of human neutrophil elastase.

Abstract: An ink reservoir for a printer with an inkjet printhead includes a housing for storing a quantity of ink; an air inlet valve having a ball biased against an aperture of the air inlet valve for sealing an interior of the housing from atmosphere; an ink outlet valve having a circular valve seat and a ball for sealing against the valve seat; and a valve actuator having a sliding shaft extending between the ink outlet valve and the air inlet valve. The valve actuator opens the air inlet valve in response to the ink outlet valve opening to establish fluid communication with the inkjet printhead. The ball in the ink outlet valve is adapted to engage one end of the sliding shaft to slide the shaft towards the air inlet valve, whereat the other end of the shaft engages the ball of the air inlet valve against the bias applied thereon.

Abstract: A system and method for pairing an X-ray system with a wireless device is provided. In one embodiment, a method includes generating a unique pairing code with control circuitry that controls the operation of the X-ray system, providing the unique pairing code to the wireless device in the form of a pulse sequence and receiving a wireless signal indicative of the unique pairing code from the wireless device. The wireless device is then paired and enabled for use with the X-ray system.

Abstract: Embodiments disclosed herein utilize Habitats to perform incremental updates on virtual machines (VMs) over time. A VM Habitat comprises a collection of VMs and a specification shared between these VMs. Each Habitat specification may define an image name, processing power, etc. A Habitat specification may exist across a cluster of servers. In some embodiments, to dynamically update a Habitat specification, only “spare” VMs in the Habitat are updated, subject to some scheduling parameters and server concurrency limit. As spare VMs are updated, they move towards the new Habitat specification. Eventually, all VMs reach this goal over time, given sufficient spare VM resources. This approach can allow the service provided by the VMs to remain operational, thus maintaining the service level required for its users. This automated process can also eliminate or otherwise reduce human error either in the server removal/insertion from/to the cluster or in the VM update itself.

Abstract: Use of a compound of formula (I) wherein R is an alicyclic group; an arylethyl group; or phenyl or benzyl substituted by halogen, lower alkyl, alkoxy, OH, NH2, NHalkyl, N(alkyl)2, CN or NO2; in the manufacture of a medicament for the therapy of hyperalgesic pain conditions and their symptoms.

Abstract: An oscillator synchronization system employs two oscillators, each of which includes an integrator which provides a ramping signal at its output, a comparator which receives the ramping signal and a reference signal at respective inputs and toggles an output when the ramping voltage crosses the reference signal, and a one-shot circuit that generates the integrator's reset signal when triggered. The system is preferably arranged such that the oscillators can be operated independently, in which case each oscillator's one-shot is triggered by its own comparator output, or synchronously, in which case each oscillator's one-shot is triggered by the other oscillator's comparator output—with the ramp signal of each oscillator operating to reset the integrator of the other oscillator. The oscillators are typically out-of-phase when synchronized, with the phase difference varying with the magnitude of the reference signals applied to the comparators.

Abstract: In one embodiment, an X-ray system includes a handheld X-ray interface device. The handheld X-ray interface device includes a wireless interface for communicating with an imaging system and a user-viewable screen configured to display patient data and to receive user input.

Abstract: An apparatus for charging multiple rechargeable devices is disclosed. The apparatus includes a hub or multiple T-connectors connected between a power source, preferably a Zinc-air battery, and several chargers, the hub/T-connectors configured to provide electrical and mechanical connectivity between the power source and the chargers. The apparatus includes housings configured to encase the chargers and to conformally receive each of the corresponding devices containing rechargeable batteries. The apparatus further includes pouches configured to removably receive chargers, devices, and the power source. When the power source voltage falls below a certain threshold, then a charger associated with a device having the smallest difference between its rated voltage and its measured voltage discontinues charging before other chargers. The apparatus is wearable by a user.

Abstract: In one embodiment, a portable radiological imaging system includes a portable base station having an X-ray source and a power supply, a wireless X-ray detector configured to receive X-ray radiation from the source and to generate image data based upon the received radiation, and a portable image processing system removably carried by the base station and configured to receive the image data from the detector and to process the image data to produce and display a user-viewable image derived from the image data.

Abstract: An oscillator synchronization system employs two oscillators, each of which includes an integrator which provides a ramping signal at its output, a comparator which receives the ramping signal and a reference signal at respective inputs and toggles an output when the ramping voltage crosses the reference signal, and a one-shot circuit that generates the integrator's reset signal when triggered. The system is preferably arranged such that the oscillators can be operated independently, in which case each oscillator's one-shot is triggered by its own comparator output, or synchronously, in which case each oscillator's one-shot is triggered by the other oscillator's comparator output—with the ramp signal of each oscillator operating to reset the integrator of the other oscillator. The oscillators are typically out-of-phase when synchronized, with the phase difference varying with the magnitude of the reference signals applied to the comparators.

Abstract: The subject disclosure is directed towards detecting malware or possible malware in an input file by allowing the input file to be opened, and by monitoring for one or more behaviors corresponding to the open file that likely indicate malware. Only certain executable files and/or file types opened thereby may be monitored, with various collected event data used for antimalware purposes when improper behavior is observed. Example behaviors include writing of a file to storage, generation of network traffic, injection of a process, running of script, and/or writing system registry data. Telemetry data and/or a sample of the file may be sent to an antimalware service, and malware remediation may be performed. Data (e.g., the collected events) may be distributed to other nodes for use in antimalware detection, e.g., to block execution of a similar file.