Abstract: A component of a slip assembly is formed by rolling sheet molding compound into a rolled charge. The rolled charge is positioned in a compression molding press and compressed to produce a molded element. The molded element is removed from the compression molding press and can be machined for use as the component of the slip assembly. The component can be a slip segment or can be a cylindrical body for the slip segment. The compound layers in the molded component can be oriented in a number of different orientations in the component and can increase the overall strength of the component.

Abstract: A panel for use in building construction comprises a substrate board having two opposed faces. A lamina is secured to a first one of the faces of the substrate board by means of one or more regions of bonding between the lamina and the board. The one or more regions of bonding cover a total area that is less than 20% of the total interfacial area between the lamina and the board.

Abstract: A slip assembly for a downhole tool, such as a bridge plug, has a slip body composed of independent segments. The segments are affixed together along their longitudinal sides by a bond, which can be composed of thermoplastic or thermoset resins, an elastomer, epoxy adhesives, bonding agent manufactured using ceramic, metallic agent, or a combination of these. The surface area over which the bonding agent is applied can be controlled for a particular implementation. Thus, more or less of the longitudinal sides of the segments can be bonded to other segments. This provides greater control of the required force to break the bond itself, which can be tailored as desired.

Abstract: A downhole tool, such as a fracture plug used during a fracture operation, installs in a downhole tubular, such as casing. The tool has a mandrel with a sealing element disposed thereon between uphole and downhole ends. Slip assemblies on the mandrel can be moved to engage the downhole tubular. The uphole assembly has inserts composed of ceramic material, and the downhole assembly has inserts composed of a metallic material. When the tool is used as a bridge plug, the uphole assembly supports the sealing element compressed, and the downhole assembly supports fluid pressure downhole of the tool. In one particular embodiment, the metallic material is a powdered metal material, such as a sintered-hardened powdered metal steel having a balance of iron, an admixture of carbon, and alloy components of molybdenum, chromium, and manganese.

Abstract: A dual protocol input device for use with a host system is provided. In one embodiment, the input device comprises a chip with a number of semiconductor devices integrally formed thereon, including: an optical navigation sensor (ONS) to sense movement of the ONS relative to a surface; a wired protocol block to communicate data from the ONS to the host system by a wired communication protocol; a wireless protocol block to communicate data from the ONS to the host system by a wireless communication protocol; and a micro-controller coupled to the ONS, the wired protocol block and the wireless protocol block, to switch the input device between the wireless communication protocol and the wired communication protocol.

Abstract: A slip assembly for a downhole tool, such as a composite plug, has a slip body and at least one insert. The slip body has an incline at one end that interfaces with an inclined surface of a cone. As this occurs, the slip body is pushed away from the tool's mandrel against a surrounding casing wall. The insert is disposed in the slip body with the axis of the insert angled away from the cone. In particular, the insert's axis is preferably angled normal to the slip body's incline and the inclined surface of the cone.

Abstract: The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.

Abstract: The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.

Abstract: The instant invention provides for compounds that inhibit JAK2 tyrosine kinase and/or PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting JAK2 tyrosine kinase activity and/or PDK1 kinase inhibitory activity by administering the compound to a patient in need of treatment or prevention of myeloproliferative disorders or cancer.

Abstract: An apparatus for connecting user equipment to a broadband network includes a chassis having attachment points for connection to a supporting surface and a guide that permits entry of a communication cable. A cable termination unit may be mounted on the chassis such that a cable that is led through the guide can be connected and provided with a termination to which functional connections can be made. A cover may be mounted on the chassis in such a way as to be removable and reattachable to allow access to the chassis. The chassis may include mounting points for connecting at least one functional module to the communication cable and for allowing different communication functions to be provided to user equipment that is connected to the network via the apparatus.

Abstract: The present invention relates to pyridazin-4(1H)-one derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

Abstract: Systems and methods are used to display cell structures of a biological cell. A plurality of cell structures of a biological cell is stored and for each cell structure of the plurality of cell structures one or more stain colors are stored. A selected cell structure is received from an input device. One or more stain colors of the selected cell structure are retrieved. The one or more stain colors of the selected cell structure are displayed. A selected stain color is received from the input device. The selected cell structure is displayed in the selected stain color in an exemplary cell image. Further, a three-dimensional image of a biological cell is stored. The three-dimensional image is displayed on a display that includes a touch screen. A movement selection is received from the touch screen. The three-dimensional image is displayed on the display according to the movement selection.

Abstract: A downhole tool, such as a packer or liner hanger, has a mandrel on which slips are disposed for engaging a surrounding tubular downhole. When the tool is being run in or out of the hole, at least one magnetic component magnetically retains the slip adjacent the mandrel so the slip can be held away from the surrounding tubular. When the tool is set downhole, the initial magnetic retention can be broken, and the slips can be moved away from the mandrel to engage the surface of the surrounding tubular.

Abstract: A method of autocalibrating the timing of the laser in a quantum key distribution (QKD) system is disclosed. The laser generates photon signals in response to a laser gating signals from a controller. The method includes first performing a laser gate scan to establish the optimum laser gating signal arrival time corresponding to an optimum bit-error rate when exchanging photon signals between encoding stations of the QKD system. Once the optimum laser gating signal arrival time is determined, the laser gate scan is terminated and laser gate dithering is initiated. Laser gate dithering involves varying the arrival time of the laser gating signal around the optimum value of the arrival time. Laser gate dithering provides minor adjustments to the laser gating signal arrival time to ensure that the system operates at or near the optimum bit-error rate.

Abstract: A downhole tool, such as a packer or liner hanger, has a mandrel on which slips are disposed for engaging a surrounding tubular downhole. When the tool is being run in or out of the hole, at least one magnetic component magnetically retains the slip adjacent the mandrel so the slip can be held away from the surrounding tubular. When the tool is set downhole, the initial magnetic retention can be broken, and the slips can be moved away from the mandrel to engage the surface of the surrounding tubular.

Abstract: A communications device, such as a mobile telephone, fixed line telephone, computer with network access, or any other similar device which is equipped to communicate using network and/or telephony protocols, is provided, wherein before a call or other communications sessions is set up and made, a determination of the present time at the intended recipient of the call or session is made. In some embodiments, this determination of the time at the intended recipient's location is displayed to a user of the calling device to allow the user to decide whether to proceed with a call to the intended recipient. In other embodiments the determined time is compared with a set of one or more predetermined time bands during which calls to a recipient should not be made. Depending on the results of the comparison, the operation of the communications device is altered, for example, in one embodiment the call is not made, and the user preferably informed.

Abstract: The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.

Abstract: Systems and methods for verifying error-free transmission of the synchronization (“sync”) channel of a QKD system are disclosed. The method includes sending a first pseudo-random bit stream (PRBS) over the sync channel from Alice to Bob, and verifying at Bob the accurate transmission of the first PRBS. The method also includes sending a second pseudo-random bit stream (PRBS) over the sync channel from Bob to Alice, and verifying at Alice the accurate transmission of the first PRBS. If the transmissions of a select number of bits in the first and second PRBSs are error-free, then the sync channel is verified and the QKD system can commence operation.

Abstract: An apparatus for connecting user equipment to a broadband network includes a chassis having attachment points for connection to a supporting surface and a guide that permits entry of a communication cable. A cable termination unit may be mounted on the chassis such that a cable that is led through the guide can be connected and provided with a termination to which functional connections can be made. A cover may be mounted on the chassis in such a way as to be removable and reattachable to allow access to the chassis. The chassis may include mounting points for connecting at least one functional module to the communication cable and for allowing different communication functions to be provided to user equipment that is connected to the network via the apparatus.