Abstract: The present invention relates to an in-vivo bulking agent which can be used as a medicinal agent for prevention or treatment of at least one disease selected from the group consisting of urinary incontinence, fecal incontinence, and gastroesophageal reflux or as a filler for use in a plastic surgery procedure, and to a preparation method therefor. The in-vivo bulking agent can exhibit a bulking effect when injected into the body and particularly, is highly biocompatible because a first composition in which silicone particles are coated with a zwitterionic polymer having a surfactant property is introduced into a second composition, whereby the bulking agent can inhibit inflammatory reactions in vivo.

Abstract: An artificial blood vessel complex includes: an artificial blood vessel tube member having a tube shape; and an artificial blood vessel ring member provided at an end of the artificial blood vessel tube member, for suturing with an aortic root through a suture, and having a curved shape with an inflection portion to correspond to a shape of an edge of the aortic root. The artificial blood vessel tube member includes: an artificial blood vessel tube portion; and a lounge tube portion extending from an end of the artificial blood vessel tube portion to be separated into a plurality of pieces, and having an end formed in a curved shape to match the artificial blood vessel ring member.

Abstract: A soft sensor includes an elastic sheet, which includes a first elastic layer and a second elastic layer facing each other, and a sensor unit formed by printing a predetermined conductive liquid metal between the first elastic layer and the second elastic layer. A hand-wearable device may include at least one soft sensor, wherein the hand-wearable device has a shape corresponding to at least a portion of a shape of a hand, and the soft sensor is located at a position corresponding to at least some joints of the hand.

Abstract: A customized guide includes a body having a shape corresponding to a main vessel in biological tissues that includes the main vessel and an accessory vessel branching from the main vessel, and an indicator provided in the body to indicate a branching location of the accessory vessel.

Abstract: The present invention relates to an in-vivo bulking agent which can be used as a medicinal agent for prevention or treatment of at least one disease selected from the group consisting of urinary incontinence, fecal incontinence, and gastroesophageal reflux or as a filler for use in a plastic surgery procedure, and to a preparation method therefor. The in-vivo bulking agent can exhibit a bulking effect when injected into the body and particularly, is highly biocompatible because a first composition in which silicone particles are coated with a zwitterionic polymer having a surfactant property is introduced into a second composition, whereby the bulking agent can inhibit inflammatory reactions in vivo.

Abstract: The present invention relates to a method for producing botulinum toxin in various fragments to then be reassembled, for safely producing same. In the present invention, devised is a method in which: botulinum toxin is produced in fragments by cleaving light and heavy chains thereof into two or three pieces, respectively, and then combined as a full-length toxin, thereby allowing high complexity in production, due to toxicity, as well as low safety and economic feasibility, to be overcome; production of water-soluble botulinum toxin is enabled by using bacteria, thereby markedly shortening the production time as compared to existing production methods; and conjugation of the produced fragments with other proteins and nanoparticles is also enabled, thereby increasing the pharmaceutical extensibility of the toxin.

Abstract: Provided is a soft sensor embedded glove including an upper inside skin pattern, a soft sensor module coupled to at least a surface of the upper inside skin pattern, and including at least one soft sensor formed on a joint portion of a finger to measure flexion and extension of the finger, and an outside skin coupled to the upper inside skin pattern and exposed to outside, wherein, in the upper inside skin pattern, a width of a region to which the at least one soft sensor is coupled is less than a width of another region.

Abstract: A hand-wearable device includes an elastic sheet including a first elastic layer and a second elastic layer facing each other; a sensor unit formed by printing a predetermined conductive liquid metal between the first elastic layer and the second elastic layer; a wire unit extending from the sensor unit and electrically connected to the sensor unit; an electrode substrate formed on one side of the wire unit and spaced apart from the wire unit by a predetermined distance; and a connection electrode formed by printing a predetermined conductive liquid metal between the wire unit and the electrode substrate.

Abstract: A method for processing an unmatched low-dose X-ray computed tomography (CT) image using a neural network and an apparatus therefor are provided. The method includes receiving a low-dose X-ray CT image and removing noise from the low-dose X-ray CT image using a unsupervised learning based neural network learned using unmatched data to reconstruct a routine-dose X-ray CT image corresponding to the low-dose X-ray CT image.

Abstract: Provided is a soft sensor embedded glove including an upper inside skin pattern, a soft sensor module coupled to at least a surface of the upper inside skin pattern, and including at least one soft sensor formed on a joint portion of a finger to measure flexion and extension of the finger, and an outside skin coupled to the upper inside skin pattern and exposed to outside, wherein, in the upper inside skin pattern, a width of a region to which the at least one soft sensor is coupled is less than a width of another region.

Abstract: A hand-wearable device includes an elastic sheet including a first elastic layer and a second elastic layer facing each other; a sensor unit formed by printing a predetermined conductive liquid metal between the first elastic layer and the second elastic layer; a wire unit extending from the sensor unit and electrically connected to the sensor unit; an electrode substrate formed on one side of the wire unit and spaced apart from the wire unit by a predetermined distance; and a connection electrode formed by printing a predetermined conductive liquid metal between the wire unit and the electrode substrate.

Abstract: A hand-wearable device includes an elastic sheet including a first elastic layer and a second elastic layer facing each other; a sensor unit formed by printing a predetermined conductive liquid metal between the first elastic layer and the second elastic layer; a wire unit extending from the sensor unit and electrically connected to the sensor unit; an electrode substrate formed on one side of the wire unit and spaced apart from the wire unit by a predetermined distance; and a connection electrode formed by printing a predetermined conductive liquid metal between the wire unit and the electrode substrate.

Abstract: The present invention relates to a composition for inhibiting the formation of a SNARE complex, containing myricetin derivatives, and having novel structures and obtained by the acylation of myricetin, laricitrin, combretol, or syringetin. The myricetin derivatives are considered to exhibit an effect of being bioconverted into myricetin in a cell. The myricetin derivatives lost the dark color of conventional myricetin and properties thereof were changed such that the myricetin derivatives have properties of photostability and fat solubility. Therefore, since stable form myricetin derivatives are absorbed into a cell such that an activity, possessed by normal myricetin, of inhibiting the formation of a SNARE complex are exhibited, the present invention can exhibit an excellent function as a SNARE targeting prodrug, and as a composition for inhibiting the formation of a SNARE complex, containing the same.

Abstract: A method for processing an unmatched low-dose X-ray computed tomography (CT) image using a neural network and an apparatus therefor are provided. The method includes receiving a low-dose X-ray CT image and removing noise from the low-dose X-ray CT image using a unsupervised learning based neural network learned using unmatched data to reconstruct a routine-dose X-ray CT image corresponding to the low-dose X-ray CT image.

Abstract: A soft sensor includes an elastic sheet, which includes a first elastic layer and a second elastic layer facing each other, and a sensor unit formed by printing a predetermined conductive liquid metal between the first elastic layer and the second elastic layer.

Abstract: A hand-wearable device includes an elastic sheet including a first elastic layer and a second elastic layer facing each other; a sensor unit formed by printing a predetermined conductive liquid metal between the first elastic layer and the second elastic layer; a wire unit extending from the sensor unit and electrically connected to the sensor unit; an electrode substrate formed on one side of the wire unit and spaced apart from the wire unit by a predetermined distance; and a connection electrode formed by printing a predetermined conductive liquid metal between the wire unit and the electrode substrate.

Abstract: Provided is a force conveyance system that is configured to have 6 degrees of freedom, thereby allowing freedom of movement such as opening/closing of a hand and adduction/abduction of a finger and reflecting a desired force to a fingertip without obstructing the movement of a finger. Also, the force conveyance system may estimate a fingertip position and a finger joint angle, measure a finger movement, and convey a more accurate force accordingly.

Abstract: Provided is a force conveyance system that is configured to have 6 degrees of freedom, thereby allowing freedom of movement such as opening/closing of a hand and adduction/abduction of a finger and reflecting a desired force to a fingertip without obstructing the movement of a finger. Also, the force conveyance system may estimate a fingertip position and a finger joint angle, measure a finger movement, and convey a more accurate force accordingly.

Abstract: The present invention relates to a composition for inhibiting the formation of a SNARE complex, containing myricetin derivatives, and having novel structures and obtained by the acylation of myricetin, laricitrin, combretol, or syringetin. The myricetin derivatives are considered to exhibit an effect of being bioconverted into myricetin in a cell. The myricetin derivatives lost the dark color of conventional myricetin and properties thereof were changed such that the myricetin derivatives have properties of photostability and fat solubility. Therefore, since stable form myricetin derivatives are absorbed into a cell such that an activity, possessed by normal myricetin, of inhibiting the formation of a SNARE complex are exhibited, the present invention can exhibit an excellent function as a SNARE targeting prodrug, and as a composition for inhibiting the formation of a SNARE complex, containing the same.

Abstract: The present invention relates to an obstacle detecting apparatus and an obstacle detecting method and an exemplary embodiment of the present invention provides an obstacle detecting apparatus, including: a stereo camera which photographs a front of a vehicle to generate a left image and a right image; an image matching unit which applies a block matching algorithm to the left image and the right image to extract a plurality of feature points having a similarity which is equal to or larger than a reference value and calculate a coordinate and a depth of the plurality of extracted feature points; a plane calculating unit which connects every three feature points of the plurality of feature points to calculate a plurality of triangles, based on the coordinate and the depth of the plurality of feature points; a normal calculating unit which calculates directions of normal of the plurality of triangles, based on the coordinate and the depth of three feature points corresponding to vertexes of the plurality of tria