Abstract: Disclosed are an automatic abrasion compensation system of a lower plate and a wafer lapping apparatus having the same. The automatic abrasion compensation system reduces wafer misloading and errors in wafer loading inspection occurring when the distance between the lower plate and a transfer robot is gradually increased due to abrasion of the lower plate during a lapping process. The automatic abrasion compensation system includes an ultrasonic sensor provided on the transfer robot, a jig located directly under the ultrasonic sensor and mounted on the lower plate, a controller configured to acquire measurement distance information by measuring a distance from the jig through the ultrasonic sensor, to compare the measurement distance information with set reference distance information and to generate an adjustment control signal, and a driver configured to automatically adjust a Z-axis position of the transfer robot depending on the adjustment control signal transmitted by the controller.

Abstract: The present disclosure relates to the use of stimulators of soluble guanylate cyclase (sGC), pharmaceutically acceptable salts thereof and pharmaceutical formulations or dosage forms comprising them, alone or in combination with one or more additional agents, for the treatment of various CNS diseases, wherein an increase in sGC stimulation, or an increase in the concentration of nitric oxide (NO), or cyclic guanosine 3?,5?-monophosphate (cGMP) or both, or an upregulation of the NO pathway is desirable.

Abstract: A display substrate according to the embodiment includes a base material containing chromium and iron, wherein the base material includes a surface portion and a central portion, the surface portion is defined as a depth region from a surface of the base material to a depth of 5 nm in a thickness direction of the base material, and a ratio of chromium atoms to iron atoms (Cr/Fe) of the surface portion is greater than that of the central portion.

Abstract: Various disclosed embodiments are directed to deriving an albedo output image from an input image based on deriving an inverse shading map. For example, an input image can be a photograph of a human face (i.e., the geometric features) with RGB values representing the color values of the face as well as pixels representing shadows (i.e., the shadow features) underneath the chin of the human face. The inverse shading map may be a black and white pixel value image that contains pixels representing the same human face without the RGB values and the shadows underneath the chin. The inverse shading map thus relies on the geometric space, rather than RGB space. Geometric space, for example, allows embodiments to capture the geometric features of a face, as opposed to those geometric features' RGB or shadow details.

Abstract: The present disclosure relates to systems, non-transitory computer-readable media, and methods that implement a multi-branch harmonization neural network architecture to harmonize composite images. For example, in one or more implementations, the semantic-guided transformer-based harmonization system uses a convolutional branch, a transformer branch, and a semantic branch to generate a harmonized composite image based on an input composite image and a corresponding segmentation mask. More particularly, the convolutional branch comprises a series of convolutional neural network layers followed by a style normalization layer to extract localized information from the input composite image. Further, the transformer branch comprises a series of transformer neural network layers to extract global information based on different resolutions of the input composite image. The semantic branch includes a visual neural network that generates semantic features that inform the harmonization of the composite images.

Abstract: A display substrate according to the embodiment includes a base material containing chromium and iron, wherein the base material includes a surface portion and a central portion, the surface portion is defined as a depth region from a surface of the base material to a depth of 5 nm in a thickness direction of the base material, and a ratio of chromium atoms to iron atoms (Cr/Fe) of the surface portion is greater than that of the central portion.

Abstract: Described herein are methods of modulating OTC gene transcription using antisense oligonucleotides (ASOs) targeting regulatory RNAs, such as promoter-associated RNAs and enhancer RNAs. These methods are useful for increasing expression of Ornithine transcarbamylase (OTC), thereby treating diseases associated with aberrant gene expression.

Abstract: One or more aspects of a method, apparatus, and non-transitory computer readable medium include obtaining an input description and an input image depicting a subject, encoding the input description using a text encoder of an image generation model to obtain a text embedding, and encoding the input image using a subject encoder of the image generation model to obtain a subject embedding. A guidance embedding is generated by combining the subject embedding and the text embedding, and then an output image is generated based on the guidance embedding using a diffusion model of the image generation model. The output image depicts aspects of the subject and the input description.

Abstract: Described herein are methods of modulating gene transcription using antisense oligonucleotides (ASOs) targeting regulatory RNAs, such as promoter-associated RNAs and enhancer RNAs. These methods are useful for modulating the levels of gene products, for example, increasing expression of Carbamoyl-Phosphatase Synthetase 1 (CPS1), thereby treating diseases associated with aberrant gene expression.

Abstract: This application relates to a method and system for cutting a brittle body. In one aspect, the method includes preparing a brittle body having a rotary shaft. The method may also include forming a scribing line by irradiating laser on the brittle body along a preset route by using a laser irradiation unit. The method may further include cutting the brittle body by bringing a vibration unit that vibrates at a preset frequency in contact with a first region of the brittle body, which is spaced apart from the scribing line.

Abstract: A radiation detection device includes a sensor having a first electrode and a second electrode. The first and second electrode each defines a plurality of fingers comprising a nanotube material, and the fingers of each electrode are interdigitated with one another. A voltage source may be configured to apply a voltage across the first and second electrodes. A chamber contains the sensor with a gas, one or more walls of the chamber enabling passage of radiation external to the chamber. A detection circuit detects radiation within the chamber based on a change in current across the first and second electrodes resulting from ionization of the gas by the radiation.

Abstract: In an alloy metal plate according to an embodiment, diffraction intensity of a (111) plane of the alloy metal plate is defined as I (111), diffraction intensity of a (200) plane of the alloy metal plate is defined as I (200), diffraction intensity of a (220) plane of the alloy metal plate is defined as I (220), a diffraction intensity ratio of I (200) is defined by the following Equation 1, and a diffraction intensity ratio of I (220) is defined by the following Equation 2. At this time, the A is 0.5 to 0.6, the B is 0.3 to 0.5, and the value A may be larger than a value B. A = I ? ( 200 ) / { I ? ( 200 ) + I ? ( 220 ) + I ? ( 111 ) } [ Equation ? 1 ] The diffraction intensity ratio of I (220) is defined by the following Equation 2.

Abstract: The present disclosure relates to the use of stimulators of soluble guanylate cyclase (sGC), pharmaceutically acceptable salts thereof and pharmaceutical formulations or dosage forms comprising them, alone or in combination with one or more additional agents, for the treatment of various CNS diseases, wherein an increase in sGC stimulation, or an increase in the concentration of nitric oxide (NO), or cyclic guanosine 3?,5?-monophosphate (cGMP) or both, or an upregulation of the NO-sGC-cGMP pathway is desirable. Compounds useful in the methods of the invention are those of Formula (I) or pharmaceutically acceptable salts thereof.

Abstract: The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutically acceptable salts thereof and pharmaceutical formulations comprising them and their uses thereof, alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) and/or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP), or both, or an upregulation of the NO pathway is desirable. In some embodiments, the compounds are those of Table I or a pharmaceutically acceptable salt thereof.

Abstract: In an alloy metal plate according to an embodiment, diffraction intensity of a (111) plane of the alloy metal plate is defined as I (111), diffraction intensity of a (200) plane of the alloy metal plate is defined as I (200), diffraction intensity of a (220) plane of the alloy metal plate is defined as I (220), a diffraction intensity ratio of I (200) is defined by the following Equation 1, and a diffraction intensity ratio of I (220) is defined by the following Equation 2. At this time, the A is 0.5 to 0.6, the B is 0.3 to 0.5, and the value A may be larger than a value B. A=I(200)/{I(200)+I(220)+I(111)}??[Equation 1] The diffraction intensity ratio of I (220) is defined by the following Equation 2.

Abstract: The present disclosure relates to systems, non-transitory computer-readable media, and methods that implement a multi-branch harmonization neural network architecture to harmonize composite images. For example, in one or more implementations, the semantic-guided transformer-based harmonization system uses a convolutional branch, a transformer branch, and a semantic branch to generate a harmonized composite image based on an input composite image and a corresponding segmentation mask. More particularly, the convolutional branch comprises a series of convolutional neural network layers followed by a style normalization layer to extract localized information from the input composite image. Further, the transformer branch comprises a series of transformer neural network layers to extract global information based on different resolutions of the input composite image. The semantic branch includes a visual neural network that generates semantic features that inform the harmonization of the composite images.

Abstract: The disclosure relates to an immersive couch, and more particularly to an immersive couch configured to be movable in three degrees of freedom using a concise and simple mechanism for moving an inflatable body, thereby not only improving convenience in use, safety, handling, storability, and maintainability, but also reducing manufacturing costs, operating costs, and maintenance costs. The immersive couch includes: a couch body formed as an inflatable body; a holding unit installed on the couch body; an actuation connecting member including one end connected to the holding unit; a rotary body connected to wind and unwind the actuation connecting member; a rotary body actuator rotating the rotary body forwards and backwards; and a controller controlling operations of the rotary body actuator.

Abstract: The present disclosure relates to the use of stimulators of soluble guanylate cyclase (sGC), pharmaceutically acceptable salts thereof and pharmaceutical formulations or dosage forms comprising them, alone or in combination with one or more additional agents, for the treatment of various CNS diseases, wherein an increase in sGC stimulation, or an increase in the concentration of nitric oxide (NO), or cyclic guanosine 3?,5?-monophosphate (cGMP) or both, or an upregulation of the NO pathway is desirable.

Abstract: The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutical formulations comprising them and their uses thereof, alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP), or both, or an upregulation of the NO pathway is desirable.