Patents by Inventor Joseph A. Herman
Joseph A. Herman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7214673Abstract: Described herein are antipyschotic compounds of formula (I) wherein, A is an optionally benzo-fused five or six member aromatic ring having zero to three hetero atoms independently selected from N, O, and S; Alk is (C1-4) alkylene optionally substituted with OH, methoxy, ethoxy, or F; Ar is optionally substituted phenyl, naphthyl, monocyclic heteroaromatic, or bicyclic heteroaromatic; R1 is hydrogen or (C1-4) alkyl optionally substituted with OH, OR3, or OCH2CH2OH, wherein R3 is (C1-2) alkyl; R2 is H, (C1-6) alkyl, halogen, fluorinated (C1-6) alkyl, OR4, SR4, NO2, CN, COR4, CONR5R6, SO2NR5R6, NR5R6, NR5COR4, NR5SO2R4, or optionally substituted phenyl, wherein R4 is hydrogen, (C1-6) alkyl, fluorinated (C1-6) alkyl, or optionally substituted phenyl, R5 and R6 are independently hydrogen, (C1-6) alkyl, or optionally substituted phenyl; Z is one or two substituents independently selected from hydrogen, halogen, (C1-6) alkyl, fluorinated (C1-6) alkyl, OR7, SR7, NO2, CN, COR7, CONR8R9, SO2NR8R9, NR8SO2RType: GrantFiled: March 17, 2003Date of Patent: May 8, 2007Assignee: Eli Lilly and CompanyInventors: Thomas Daniel Aicher, Zhaogen Chen, Joseph Herman Krushinski, Jr., Yvan Le Huerou, Marta Maria Pineiro-Nunez, Kevin Michael Ruley, John Mehnert Schaus, Dennis Charles Thompson, David Edward Tupper, Ying Chen, Margaret Mary Faul, Vincent Patrick Rocco
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Publication number: 20060062370Abstract: A call completion system, method and apparatus for integrated directory assistance and voice activated dialing based upon call transfer rules. In accordance with the present invention, a call completion system can include a set of call transfer rules implicating one of a directory assistance interface and a voice activated dialer interface. The system further can include a call completion processor configured to select one of a directory assistance interface and a voice activated dialer interface based upon an evaluation of the call transfer rules for an incoming query.Type: ApplicationFiled: September 22, 2004Publication date: March 23, 2006Applicant: International Business Machines CorporationInventors: Ciprian Agapi, Can Boyacigiller, Brent Davis, Joseph Herman, Vanessa Michelini, Michael Mirt, Melanie Polkosky, Jonathan White, Frankie Wilson
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Publication number: 20050234811Abstract: A computer-implemental method of transacting a sealed bid competition has deadline-assurance process which in part upholds the integrity of the sealed bid competition. In a sealed bid competition, a buyer originates a “request for bid” communication that specifies bid items as well as includes a parameter of deadline. Participating vendors respond with “response” communications that contain substantive content presumptively responsive to the “request for bid” communication. The object of a sealed bid competition is to keep everyone, including especially the buyer, blind to the bid responses of everyone else until after the deadline. The deadline-integrity process has the buyer either precluded from access to the “response” communications until the deadline or else has the buyer's activity with accessing the “response” communications is logged so that such log record can thereafter disclose if the buyer voluntarily restrained itself from accessing the “response” communications until after the deadline.Type: ApplicationFiled: May 11, 2005Publication date: October 20, 2005Inventors: Joseph Herman, Darren Henderson, Erick Burgess
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Patent number: 6899294Abstract: A method and apparatus for separating the organic membrane portion of waste egg shells from the hard inorganic mineral portion thereof, so that each can be used or further processed as desired, thereby addressing the environmental and economic issues associated with disposing of waste egg shells. The membrane and shell are separated by first processing waste eggshells so as to yield small waste eggshell particles. During this processing, the waste eggshell particles are at least slightly abraded, whereby the linking structure between the membrane and shell is at least partially disrupted. Thereafter, the waste eggshell particles are conveyed to a device, which isolates the two components based on their size and weight differences. The methods listed above can provide products from the eggshell waste including precipitated calcium carbonate, membrane, protein, amino acids, collagen and other important components.Type: GrantFiled: March 30, 2001Date of Patent: May 31, 2005Assignee: The Penn State Research FoundationInventor: Joseph Herman MacNeil
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Patent number: 6777428Abstract: The present invention relates to a compound of formula I and a process for making: or a pharmaceutical acid addition salt thereof; which are useful for activating 5-HT1F receptors and inhibiting neuronal protein extravasation in a mammal.Type: GrantFiled: December 4, 2001Date of Patent: August 17, 2004Assignee: Eli Lilly and CompanyInventors: Joseph Herman Krushinski, Jr., Vincent Mancuso, Freddy Andre Napora, John Mehnert Schaus
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Publication number: 20040102481Abstract: The present invention relates to compounds of formula I: which are antagonists of 5-HT6 receptor.Type: ApplicationFiled: July 22, 2003Publication date: May 27, 2004Inventors: Sandra Ann Filla, Michael Edward Flaugh, James Ronald Gillig, Lawrence Joseph Heinz, Joseph Herman Krushinski, Bin Liu, Marta Maria Pineiro-Nunez, John Mehnert Schaus, John Stanley Ward
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Publication number: 20030209617Abstract: A method and apparatus for separating the organic membrane portion of waste egg shells from the hard inorganic mineral portion thereof, so that each can be used or further processed as desired, thereby addressing the environmental and economic issues associated with disposing of waste egg shells. The membrane and shell are separated by first processing waste eggshells so as to yield small waste eggshell particles. During this processing, the waste eggshell particles are at least slightly abraded, whereby the linking structure between the membrane and shell is at least partially disrupted. Thereafter, the waste eggshell particles are conveyed to a device, which isolates the two components based on their size and weight differences. The methods listed above can provide products from the eggshell waste including precipitated calcium carbonate, membrane, protein, amino acids, collagen and other important components.Type: ApplicationFiled: November 19, 2002Publication date: November 13, 2003Inventor: Joseph Herman MacNeil
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Patent number: 6276983Abstract: The present invention involves a method for simultaneously applying an activation layer on the photoemissive layers of a plurality of photocathodes such as those used in image intensifier devices. The method includes the steps of diffusing a flux of activating chemicals over the plurality of photocathodes, wherein the flux is substantially spatially uniform with respect to the plurality of photocathodes; monitoring the sum photoresponse of the plurality of photocathodes; and terminating the flux of activating chemicals when a desired sum photoresponse is attained.Type: GrantFiled: May 30, 2000Date of Patent: August 21, 2001Assignee: ITT Manufacturing Enterprises, Inc.Inventors: Robert Peckman, Donald H. Stanley, Roger M. Voss, Joseph Herman Reich, Jr.
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Patent number: 6225307Abstract: A pharmaceutical composition that inhibits or slows the growth of viruses in animals, particularly in mammals, is disclosed. This same composition is can be used to treat viral infections, particularly HIV. The composition comprises from about 10 mg to about 10000 mg of a carbamic acid ester derivative of the formula: wherein X is independently oxygen or sulfur, R is selected from the group consisting of hydrogen and alkyl having from 1 to 4 carbon atoms, R1 is selected from the group consisting of hydrogen and alkyl having from 1 to 4 carbon atoms, wherein R2 is independently selected from the group consisting of hydrogen and alkyl having from 1 to 4 carbon atoms, and wherein Y is selected from the group consisting of hydrogen, chloro, fluoro, bromo, hydroxy, oxychloro and sulfhydryl or pharmaceutical addition salt or prodrug thereof. The most preferred compound is (4-chlorophenyl)-carbamic acid, 3-(hexahydro-3-ethyl-1-methyl-2-oxo-1H-azepin-3-yl) 2 phenyl ester.Type: GrantFiled: March 29, 2000Date of Patent: May 1, 2001Assignee: The Procter & Gamble CompanyInventors: James Berger Camden, Joseph Herman Gardner, David Thomas Stanton
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Patent number: 6194430Abstract: A pharmaceutical composition is disclosed to treat viral infections, particularly HIV and hepatitis, as well as to treat fungal infections of the genus cryptococcus neoformans or curvularai lunata. The composition comprises from about 10 mg to about 6000 mg of a 2-thienyl-imidazolo [4,5]pyridine of the formula: wherein n is from 1 to 4, R is selected from the group consisting of hydrogen, alkyl having from 1 to 7 carbon atoms, chloro, bromo or fluoro, oxychloro, hydroxy, sulfhydryl, alkoxy having the formula —O(CH2)yCH3 wherein y is from 1 to 6, the prodrugs thereof, and the pharmaceutically acceptable salts thereof. The preferred anti-viral compound is or its hydrochloride salt.Type: GrantFiled: March 29, 2000Date of Patent: February 27, 2001Assignee: The Procter & Gamble CompanyInventors: James Berger Camden, Joseph Herman Gardner, David Thomas Stanton
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Patent number: 6133290Abstract: The present invention relates to a compound of formula I: ##STR1## or a pharmaceutical acid addition salt thereof; which are useful for activating 5-HT.sub.1F receptors and inhibiting neuronal protein extravasation in a mammal.Type: GrantFiled: June 16, 1999Date of Patent: October 17, 2000Assignee: Eli Lilly and CompanyInventors: Joseph Herman Krushinski, Jr., John Mehnert Schaus
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Patent number: 6086944Abstract: The present invention involves a method for simultaneously applying an activation layer on the photoemissive layers of a plurality of photocathodes such as those used in image intensifier devices. The method includes the steps of diffusing a flux of activating chemicals over the plurality of photocathodes, wherein the flux is substantially spatially uniform with respect to the plurality of photocathodes; monitoring the sum photoresponse of the plurality of photocathodes; and terminating the flux of activating chemicals when a desired sum photoresponse is attained.Type: GrantFiled: February 18, 1997Date of Patent: July 11, 2000Assignee: ITT Manufacturing Enterprises, Inc.Inventors: Robert Peckman, Donald H. Stanley, Roger M. Voss, Joseph Herman Reich, Jr.
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Patent number: 5962474Abstract: This invention provides novel 5-HT.sub.1F agonists of Formula I ##STR1## where A--B, R,R.sup.1 and X are as defined in the specification, which are useful for the treatment of migraine and associated disorders.Type: GrantFiled: November 24, 1997Date of Patent: October 5, 1999Assignee: Eli Lilly and CompanyInventors: James Edmund Audia, Bruce Anthony Dressman, James Joseph Droste, James Erwin Fritz, Stephen Warren Kaldor, Daniel James Koch, Joseph Herman Krushinski, Jr., Jeffrey Scott Nissen, Vincent Patrick Rocco, John Mehnert Schaus, Dennis Charles Thompson
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Patent number: 5708008Abstract: This invention provides novel 5-HT.sub.1F agonists of Formula I ##STR1## where A--B, R, R.sup.1 and X are as defined in the specification, which are useful for the treatment of migraine and associated disorders.Type: GrantFiled: March 20, 1996Date of Patent: January 13, 1998Assignee: Eli Lilly and CompanyInventors: James Edmund Audia, Bruce Anthony Dressman, James Joseph Droste, James Erwin Fritz, Stephen Warren Kaldor, Daniel James Koch, Joseph Herman Krushinski, Jr., Jeffrey Scott Nissen, Vincent Patrick Rocco, John Mehnert Schaus, Dennis Charles Thompson
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Patent number: 4623149Abstract: A longitudinal live rubber bowling ball insert having the purpose of providing a finger hole which is of a size which more properly matches the finger size of the user and, in which an internal wall portion of the insert is provided with a plurality of grooves, said grooves greatly increasing the "lift" which may be applied to the ball by the user resulting with the bowling ball having a more pronounced hook as it travels down the bowling alley. The insert is angled on both opposing ends, thus enabling the insert to be used in bowling balls drilled for right-handed or left-handed bowlers. The terminating angle is necessary in order that the insert, once placed in the bowling ball, does not extend out beyond the ball surface.Type: GrantFiled: May 3, 1985Date of Patent: November 18, 1986Inventor: Joseph Herman
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Patent number: 4567707Abstract: A flat keyway joint member having a multiplicity of sides, each side having a keyway slot for receiving an arcuately disposed elongated key. A predetermined number of joint members and key members are connected together for the assembly of a particularly designed member resulting in a structure completely closed upon itself. This invention may be used to construct geodesic structures and the like for such wide and varied use such as planters, greenhouses, etc. When used in greenhouse construction, the entire greenhouse can be assembled on the ground and simply raised when completed.Type: GrantFiled: April 9, 1984Date of Patent: February 4, 1986Inventor: Joseph Herman
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Patent number: 4095162Abstract: A capacity changer device in which there is a first capacitor means of the 1-terminal capacitor type, and an enclosing hollow metal sphere enclosing the first capacitor means which may be spaced therefrom and being itself a 1-terminal capacitor with a current power supply for energizing a number of evacuated glass tubes containing an ionizable gas and forming part of the first capacitor means. It includes a second power suppy for direct current for charging the first capacitor means and connected also to the metal sphere for combining the charge to form a combination with the sphere of a change to a 2-terminal capacitor.Type: GrantFiled: November 3, 1975Date of Patent: June 13, 1978Inventor: Joseph Herman Arnold Peter Hiddink
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Patent number: 4087490Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen, alkyl, alkenyl, cycloalkyl, aryl, alkaryl, aralkyl, halogen, cyano, nitro, alkoxy, alkylthio, aryloxy, haloalkyl, and haloaryl, n is 0, 1, 2, 3 or 4; X is oxygen or sulfur, Y is chlorine or bromine and a process for the production of these; and for the conversion of these to valuable insecticides by reacting same with an alkanol.Type: GrantFiled: July 20, 1976Date of Patent: May 2, 1978Assignee: Makhteshim Chemical Works, Ltd.Inventors: Joseph Herman Lesser, Ludmila Friedman