Patents by Inventor Joseph A. Izatt

Joseph A. Izatt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10660519
    Abstract: Systems and methods for eye tracking for motion corrected ophthalmic optical coherence tomography (OCT) are disclosed. According to an aspect, an imaging system includes an eye tracking device configured to determine movement of an eye. The imaging system also includes an OCT apparatus configured to generate OCT images of a retina of the eye. The OCT apparatus includes a scanner operable to be moved for relocating an OCT scan pivot at a pupil plane for image capture and during capture of the OCT images. The imaging system also includes a controller configured to control the scanner to relocate the OCT scan pivot at the pupil plane based on the determined movement of the eye.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: May 26, 2020
    Assignee: Duke University
    Inventors: Oscar M. Carrasco-Zevallos, Joseph A. Izatt, Christian B. Viehland, Ryan McNabb
  • Patent number: 10366492
    Abstract: Disclosed herein are systems and method for segmentation and identification of structured features in images. According to an aspect, a method may include representing an image as a graph of nodes connected together by edges. For example, the image may be an ocular image showing layered structures or other features of the retina. The method may also include adding, to the graph, nodes adjacent to nodes along first and second sides of the graph. The added nodes may have edge weights less than the nodes along the first and second sides of the graph. Further, the method may include assigning start and end points to any of the added nodes along the first and second sides, respectively. The method may also include graph cutting between the start and end points for identifying a feature in the image.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: July 30, 2019
    Assignee: Duke University
    Inventors: Sina Farsiu, Stephanie J. Chiu, Cynthia A. Toth, Joseph A. Izatt, Xiao T. Li, Peter Christopher Nicholas
  • Patent number: 10238279
    Abstract: Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope are disclosed herein. According to an aspect, a system includes first and second eyepieces. The system includes a display having first and second display portions, configured to display first images in the first display portion, and configured to display second images in the second display portion. The first image and the second image are projected along a first pathway and a second pathway. The system includes a first optical element positioned to relay the first images into the first eyepiece. The system includes a second optical element positioned to relay the second images into the second eyepiece.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: March 26, 2019
    Assignee: Duke University
    Inventors: Joseph A. Izatt, Liangbo Shen, Oscar M. Carrasco-Zevallos, Cynthia Toth
  • Publication number: 20190015167
    Abstract: Systems and methods for arbitrary viewpoint robotic manipulation and robotic surgical assistance are disclosed. According to an aspect, a system includes one or more controllers configured to receive an image dataset of an actual environment within which the robotic tool is positioned. The controller(s) are also configured to generate a virtual environment of the actual environment based on the image dataset. Further, the controller(s) can control display of the virtual environment including a virtual tool controllable by a user for use to control the robotic tool within the actual environment. The controller(s) can receive user input for altering a perspective view of display of the virtual environment from a first perspective view to a second perspective view. Further, the controller(s) can maintain orientation of display of the virtual tool with respect to the user during display of the first perspective view and the second perspective view of the virtual environment.
    Type: Application
    Filed: September 12, 2016
    Publication date: January 17, 2019
    Inventors: Mark Draelos, Kris Hauser, Anthony Kuo, Brenton Keller, Joseph Izatt
  • Publication number: 20180299658
    Abstract: Systems and methods of optical coherence tomography stereoscopic imaging for microsurgery visualization are disclosed. In accordance with an aspect, a method includes capturing a plurality of cross-sectional images of a subject. The method includes generating a stereoscopic left image and right image of the subject based on the cross-sectional images. Further, the method includes displaying the stereoscopic left image and the right image in a display of a microscope system.
    Type: Application
    Filed: April 22, 2016
    Publication date: October 18, 2018
    Inventors: Oscar M. Carrasco-Zevallos, Brenton Keller, Liangbo Shen, Christian B. Viehland, Cynthia A. Toth, Joseph A. Izatt
  • Publication number: 20180296087
    Abstract: Systems and methods for long working distance optical coherence tomography (OCT). According to an aspect, an OCT system includes a reference arm. Further, the OCT system includes a sample arm operably connected to the reference arm. The sample arm includes a scanner configured to scan an optical beam. The sample arm also includes an objective positioned a predetermined distance from the scanner, configured to receive the optical beam, and to direct the optical beam to an object positioned at about the predetermined distance from the scanner for imaging of the object.
    Type: Application
    Filed: May 5, 2016
    Publication date: October 18, 2018
    Inventors: Oscar M. Carrasco-Zevallos, Justin Migacz, Cynthia A. Toth, Joseph A. Izatt
  • Patent number: 10092180
    Abstract: OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal power optimized for a diameter of the spherical-type eye is provided along with a reference arm path length adjustment module coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye diameter of the subject.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: October 9, 2018
    Assignee: Bioptigen, Inc.
    Inventors: Robert H. Hart, Eric L. Buckland, Glenn A. Myers, Joseph A. Izatt, Joseph Elliott Vance
  • Publication number: 20180271367
    Abstract: Compact telescope configurations for light scanning systems and related methods are disclosed. According to an aspect, a system for imaging or relaying an image of an object includes a first optical element having a first focal length f1 for imaging or relaying an image of an object at the distance f1 from the first optical element. The system also includes a second optical element having a second focal length f2 for receiving an image of the object from the first optical element and for focusing an output of the image at the distance f2 from the second optical element on a side that opposes the first optical element. The first optical element and the second optical element are separated by a distance of approximately [Formula I], wherein r is the finite radius of curvature of the wavefront of light located at the object or image of the object.
    Type: Application
    Filed: February 5, 2016
    Publication date: September 27, 2018
    Applicant: Duke University
    Inventors: Joseph A. Izatt, Francesco Larocca, Theodore Dubose, Derek Nankivil
  • Patent number: 10060720
    Abstract: Frequency domain optical coherence imaging systems have an optical source, an optical detector and an optical transmission path between the optical source and the optical detector. The optical transmission path between the optical source and the optical detector reduces an effective linewidth of the imaging system. The optical source may be a broadband source and the optical transmission path may include a periodic optical filter.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: August 28, 2018
    Assignee: Bioptigen, Inc.
    Inventors: Joseph A. Izatt, Eric L. Buckland, William J. Brown
  • Patent number: 10004397
    Abstract: The present invention is directed to a method and system for improved aiming during Optical Coherence Tomography (OCT) on young children and those unable to cooperate with OCT imaging by synchronization with retinal birefringence scanning (RBS). OCT is performed without knowing whether or not the subject is looking at the intended target. The present invention combines OCT retinal imaging, such as, but not limited to, time domain OCT, SDOCT, or SSOCT, with RBS technology that provides accurate information on the presence or absence of foveal fixation. Therefore, the present invention only analyzes data during foveal fixation. A system combining OCT with RBS is implemented such that both systems co-operate in a specified alignment, such that when the RBS fixation detection system detects alignment with the fovea of the eye, the OCT system will be aimed at the retinal region of interest, usually but not necessarily including the macular area.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: June 26, 2018
    Assignees: The Johns Hopkins University, Duke University
    Inventors: Boris Gramatikov, David Lee Guyton, Kristina Irsch, Cynthia Toth, Oscar Carrasco-Zevallos, Joseph Izatt
  • Patent number: 9940722
    Abstract: Segmentation and identification of closed-contour features in images using graph theory and quasi-polar transform are disclosed. According to an aspect, a method includes representing, in a rectangular domain, an image including a feature of interest. Further, the method includes determining a point within the feature of interest. The method also includes transforming the image of the feature from the rectangular domain to a quasi-polar domain based on the point. The quasi-polar domain is represented as a graph of nodes connected together by edges. The method also includes graph cutting the quasi-polar domain to identify the boundary of the feature of interest in the image.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: April 10, 2018
    Assignee: Duke University
    Inventors: Sina Farsiu, Stephanie J. Chiu, Joseph A. Izatt
  • Patent number: 9936868
    Abstract: A system for obtaining low-angle circumferential optical access to an eye of a subject. The system includes a light source to generate a beam of light; a beam steering mechanism to steer the beam of light a focusing lens to focus the beam of light; and a contact lens to direct the beam of light into the eye of the subject, the contact lens including a tapered reflective surface to direct the beam of light into the eye of the subject.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: April 10, 2018
    Assignee: Duke University
    Inventors: Joseph A. Izatt, Anthony N. Kuo, Ryan P. McNabb
  • Publication number: 20180084992
    Abstract: OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal power optimized for a diameter of the spherical-type eye is provided along with a reference arm path length adjustment module coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye diameter of the subject.
    Type: Application
    Filed: November 13, 2017
    Publication date: March 29, 2018
    Inventors: Robert H. Hart, Eric L. Buckland, Glenn A. Myers, Joseph A. Izatt, Joseph Elliott Vance
  • Patent number: 9867536
    Abstract: Optical coherence tomography systems for imaging a whole eye are provided including a sample arm including focal optics that are configured to rapidly switch between at least two scanning modes in less than about 1.0 second.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: January 16, 2018
    Assignee: Bioptigen, Inc.
    Inventors: Joseph A. Izatt, Eric L. Buckland, Bradley A. Bower, Robert H. Hart
  • Publication number: 20180008140
    Abstract: Stereoscopic display systems and methods for displaying surgical data and information in a surgical microscope are disclosed herein. According to an aspect, a system includes first and second eyepieces. The system includes a display having first and second display portions, configured to display first images in the first display portion, and configured to display second images in the second display portion. The first image and the second image are projected along a first pathway and a second pathway. The system includes a first optical element positioned to relay the first images into the first eyepiece. The system includes a second optical element positioned to relay the second images into the second eyepiece.
    Type: Application
    Filed: February 5, 2016
    Publication date: January 11, 2018
    Inventors: Joseph A. Izatt, Liangbo Shen, Oscar M. Carrasco-Zevallos, Cynthia Toth
  • Patent number: 9864183
    Abstract: Systems and methods for structured illumination super-resolution phase microscopy are disclosed. According to an aspect, an imaging system includes a light source configured to generate light. The system also includes a diffraction grating positioned to receive and diffract the output light. The system also includes a sample holder positioned to receive the diffracted light for transmission through a sample. Further, the system includes an image detector positioned to receive the light transmitted through the sample and configured to generate image data based on the received light. The system also includes a computing device configured to apply subdiffraction resolution reconstruction to the image data for generating an image of the sample.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: January 9, 2018
    Assignee: DUKE UNIVERSITY
    Inventors: Joseph A. Izatt, Shwetadwip Chowdhury
  • Patent number: 9814383
    Abstract: OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal power optimized for a diameter of the spherical-type eye is provided along with a reference arm path length adjustment module coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye diameter of the subject.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: November 14, 2017
    Assignee: Bioptigen, Inc.
    Inventors: Robert H. Hart, Eric L. Buckland, Glenn A. Myers, Joseph A. Izatt, Joseph Elliott Vance
  • Publication number: 20170311797
    Abstract: Whole eye optical coherence tomography (OCT) imaging systems and related methods are disclosed. According to an aspect, an OCT imaging system includes a source having an associated source arm path. Further, the OCT imaging system includes a reference arm coupled to the source arm. Further, the OCT imaging system includes a sample arm having an associated sample arm path and coupled to the source arm. The sample arm includes at least one optical component configured to simultaneously scan both an anterior and posterior portion of an eye of a subject.
    Type: Application
    Filed: May 1, 2017
    Publication date: November 2, 2017
    Inventors: Anthony Kuo, Joseph Izatt, Ryan McNabb
  • Publication number: 20170188817
    Abstract: OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal power optimized for a diameter of the spherical-type eye is provided along with a reference arm path length adjustment module coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye diameter of the subject.
    Type: Application
    Filed: March 21, 2017
    Publication date: July 6, 2017
    Inventors: Robert H. Hart, Eric L. Buckland, Glenn A. Myers, Joseph A. Izatt, Joseph Elliott Vance
  • Publication number: 20170140544
    Abstract: Disclosed herein are systems and method for segmentation and identification of structured features in images. According to an aspect, a method may include representing an image as a graph of nodes connected together by edges. For example, the image may be an ocular image showing layered structures or other features of the retina. The method may also include adding, to the graph, nodes adjacent to nodes along first and second sides of the graph. The added nodes may have edge weights less than the nodes along the first and second sides of the graph. Further, the method may include assigning start and end points to any of the added nodes along the first and second sides, respectively. The method may also include graph cutting between the start and end points for identifying a feature in the image.
    Type: Application
    Filed: January 31, 2017
    Publication date: May 18, 2017
    Inventors: Sina Farsiu, Stephanie J. Chiu, Cynthia A. Toth, Joseph A. Izatt, Xiao T. Li, Peter Christopher Nicholas