Abstract: Systems and methods are provided for controlling a plurality optical resonators along a common control bus. Examples include a plurality of resonators coupled to a plurality of tuning mechanisms, a control bus connected to the plurality of tuning mechanisms, and a resonator controller configured to input a data stream onto the control bus. The data stream includes a plurality of request data packets which are being assigned to respective ones of the plurality of resonators. The plurality of tuning mechanisms are configured to adjust resonance wavelengths of the plurality of resonators based on receiving the data stream.

Abstract: Disclosed herein are screening methods for identifying cell surface receptors for progranulin. Also disclosed herein are screening methods for identifying intracellular proteins bind to progranulin.

Abstract: A method for multi-track environmental fault monitoring for aerial platforms includes estimating a normalized squared residual error (NSRE) for each of one or more satellite-receiver tracks over time. The method also includes determining an averaged NSRE for each satellite-receiver track by averaging the NSRE over multiple time windows. The method further includes performing a threshold test on the averaged NSRE to determine a filter state. In addition, the method includes determining whether to apply a scale factor for each satellite-receiver track based on the filter state.

Abstract: A method includes repeatedly determining a distance of an aircraft from a landing location. The method also includes, during a first stage in which the aircraft is at least a threshold distance from the landing location, performing iono-free processing during navigation of the aircraft. The method further includes, during a second stage in which the aircraft is less than the threshold distance from the landing location and a velocity of the aircraft is greater than a velocity threshold, performing divergence-free processing during navigation of the aircraft to address possible ionospheric threats. In addition, the method includes, during a third stage in which the aircraft is less than the threshold distance from the landing location and the velocity of the aircraft is less than the velocity threshold, calculating one or more floor values for a Differential Ionospheric Correction (DIC) sigma, and determining a navigation solution to protect against nominal ionospheric conditions.

Abstract: A method for multi-track environmental fault monitoring for aerial platforms includes estimating a normalized squared residual error (NSRE) for each of one or more satellite-receiver tracks over time. The method also includes determining an averaged NSRE for each satellite-receiver track by averaging the NSRE over multiple time windows. The method further includes performing a threshold test on the averaged NSRE to determine a filter state. In addition, the method includes determining whether to apply a scale factor for each satellite-receiver track based on the filter state.

Abstract: A method includes repeatedly determining a distance of an aircraft from a landing location. The method also includes, during a first stage in which the aircraft is at least a threshold distance from the landing location, performing iono-free processing during navigation of the aircraft. The method further includes, during a second stage in which the aircraft is less than the threshold distance from the landing location and a velocity of the aircraft is greater than a velocity threshold, performing divergence-free processing during navigation of the aircraft to address possible ionospheric threats. In addition, the method includes, during a third stage in which the aircraft is less than the threshold distance from the landing location and the velocity of the aircraft is less than the velocity threshold, calculating one or more floor values for a Differential Ionospheric Correction (DIC) sigma, and determining a navigation solution to protect against nominal ionospheric conditions.

Abstract: A three-dimensional printing system includes a print engine and a controller. The controller in turn includes a processor coupled to a non-transient memory. The non-transient memory stores software instructions that when executed by the processor cause the controller to operate the print engine to fabricate a body. The body includes a three-dimensional arrangement of 3D articles that are pairwise coupled together. An individual pair of the arrangement of 3D articles includes a first article and a second article. A curved body couples a first surface of the first article to the second article. The curved body intersects the first surface to define a closed intersection curve that bounds a break surface. Along the closed intersection curve a surface of the curved body subtends an acute angle with the first surface.

Abstract: A substrate support device includes a blade and at least one pad provided on the blade to support a substrate. The pad includes a first fixed member, a second fixed member, and a bridge. The first fixed member is provided at an outer portion of the blade. The outer portion is located outside an outer circumference portion of the substrate when the substrate is supported on the pad. The second fixed member is provided at an inner portion of the blade. The inner portion is under the substrate when the substrate is supported on the pad. The bridge is flexible and connects the first fixed member and the second fixed member to support the outer circumference portion of the substrate. An upper surface of the bridge is inclined downward from the first fixed member toward the second fixed member when the substrate is not supported on the pad.

Abstract: A three-dimensional printing system includes a print engine and a controller. The controller in turn includes a processor coupled to a non-transient memory. The non- transient memory stores software instructions that when executed by the processor cause the controller to operate the print engine to fabricate a body. The body includes a three-dimensional arrangement of 3D articles that are pairwise coupled together. An individual pair of the arrangement of 3D articles includes a first article and a second article. A curved body couples a first surface of the first article to the second article. The curved body intersects the first surface to define a closed intersection curve that bounds a break surface. Along the closed intersection curve a surface of the curved body subtends an acute angle with the first surface.

Abstract: A substrate support device includes a blade and at least one pad provided on the blade to support a substrate. The pad includes a first fixed member, a second fixed member, and a bridge. The first fixed member is provided at an outer portion of the blade. The outer portion is located outside an outer circumference portion of the substrate when the substrate is supported on the pad. The second fixed member is provided at an inner portion of the blade. The inner portion is under the substrate when the substrate is supported on the pad. The bridge is flexible and connects the first fixed member and the second fixed member to support the outer circumference portion of the substrate. An upper surface of the bridge is inclined downward from the first fixed member toward the second fixed member when the substrate is not supported on the pad.

Abstract: A method of fabricating an electrical circuit assembly on a flexible substrate comprises: identifying one or more bending-sensitive elements of an electrical circuit assembly, each bending-sensitive element having a performance that varies when said bending-sensitive element is flexed; splitting said one or more bending-sensitive elements into a first portion and a second portion, wherein the first portion and the second portion are functionally equivalent and together equate to said bending-sensitive element; printing the first portion of said bending-sensitive element on a first surface of the flexible substrate; printing the second portion of said bending-sensitive element on a second surface of the flexible substrate, diametrically opposite the first portion such that bending of the flexible substrate has an opposite effect on each of the first and second portions thereby serving to substantially cancel the effect on each portion out; and electrically connecting the first portion and the second portion.

Abstract: A method of fabricating an electrical circuit assembly on a flexible substrate comprises: identifying one or more bending-sensitive elements of an electrical circuit assembly, each bending-sensitive element having a performance that varies when said bending-sensitive element is flexed; splitting said one or more bending-sensitive elements into a first portion and a second portion, wherein the first portion and the second portion are functionally equivalent and together equate to said bending-sensitive element; printing the first portion of said bending-sensitive element on a first surface of the flexible substrate; printing the second portion of said bending-sensitive element on a second surface of the flexible substrate, diametrically opposite the first portion such that bending of the flexible substrate has an opposite effect on each of the first and second portions thereby serving to substantially cancel the effect on each portion out; and electrically connecting the first portion and the second portion.

Abstract: The concepts, systems and methods described herein are directed towards real time carrier phase monitoring and platform attitude solutions on a moving platform. In an embodiment, highly accurate platform attitude and monitored carrier phases can be determined in a single step and use data screening, error bounds inflation and statistical tests to ensure both inputs and outputs of an attitude solution are self-consistent. The method includes determining a carrier phase error level for each of the satellite-receiver tracks, identifying the satellite-receiver tracks having the carrier phase error level greater than or equal to a carrier phase error threshold, generating an attitude correction using the received data from the one or more satellite-receiver tracks having the carrier phase error level less than the carrier phase error threshold and determining a convergence state of the attitude correction. The carrier phase monitoring may be activated or dis-activated based on the convergence level.

Abstract: The concepts, systems and methods described herein are directed towards real time carrier phase monitoring and platform attitude solutions on a moving platform. In an embodiment, highly accurate platform attitude and monitored carrier phases can be determined in a single step and use data screening, error bounds inflation and statistical tests to ensure both inputs and outputs of an attitude solution are self-consistent. The method includes determining a carrier phase error level for each of the satellite-receiver tracks, identifying the satellite-receiver tracks having the carrier phase error level greater than or equal to a carrier phase error threshold, generating an attitude correction using the received data from the one or more satellite-receiver tracks having the carrier phase error level less than the carrier phase error threshold and determining a convergence state of the attitude correction. The carrier phase monitoring may be activated or dis-activated based on the convergence level.

Abstract: An assembly for an inflatable structure such as a child's bounce house, and for storing and transporting the bounce house, includes a wheeled dolly having a handle, an electric air blower mounted to the dolly near the wheels, an adapter for use in deflating the bounce house using the air blower, and a cover that is attached or attachable to the dolly for securing the bounce house in its deflated state to the dolly and for covering the bounce house.

Abstract: An oral formulation as described herein can comprise pomegranate extract, panax ginseng extract, and c. sinensis, where each is present in an amount effective to counteract and/or prevent effects of aging in a subject when administered to the subject. The effects of aging can include age-related changes in gene expression.

Abstract: Markers of caloric restriction (CR) can be identified in a selected tissue by exposing an animal to CR conditions and selecting one or more genes differentially expressed in response to CR conditions in multiple subject groups. A candidate compound can be screened for likely ability to mimic the effects of CR when administered to an animal by comparing the tissue levels of expression products of the genes in animals treated with the candidate compound to those of animals subjected to CR.

Abstract: Markers of caloric restriction (CR) can be identified in a selected tissue by exposing an animal to CR conditions and selecting one or more genes differentially expressed in response to CR conditions in multiple subject groups. A candidate compound can be screened for likely ability to mimic the effects of CR when administered to an animal by comparing the tissue levels of expression products of the genes in animals treated with the candidate compound to those of animals subjected to CR.

Abstract: Markers of caloric restriction (CR) can be identified in a selected tissue by exposing an animal to CR conditions and selecting one or more genes differentially expressed in response to CR conditions in multiple subject groups. A candidate compound can be screened for likely ability to mimic the effects of CR when administered to an animal by comparing the tissue levels of expression products of the genes in animals treated with the candidate compound to those of animals subjected to CR.

Abstract: An oral formulation as described herein can comprise pomegranate extract, panax ginseng extract, and c. sinensis, where each is present in an amount effective to counteract and/or prevent effects of aging in a subject when administered to the subject. The effects of aging can include age-related changes in gene expression.