Abstract: The present disclosure relates to heterocyclic compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis.

Abstract: A water treatment system includes a main container defining an interior and having an upper edge, a reservoir removably insertable into the interior and located upon the upper edge, the reservoir defining a cartridge seat including a plurality of holes in communication with a helical thread, and an annular landing vertically depending from the thread, a filter cartridge including a cap associated with a sump body and having a filter media in the sump body, the cap having a plurality of radially outwardly projecting pins constructed and arranged for engaging the holes and the helical thread, an annular seal disposed externally on the sump body and spaced below the cap. The filter cartridge and the cartridge seat are configured so that upon the cap pins engaging the helical thread, upon reaching a fully engaged position of the cap in the thread, the seal is compressed against the annular landing.

Abstract: An electronic device is provided. The electronic device includes a display, a short-range communication module, at least one sensor, at least one processor, and memory, including one or more storage media, storing instructions, wherein the instructions, when executed by the at least one processor individually or collectively, cause the electronic device to obtain identification information of an accessory via the short-range communication module, based on a signal detected by the at least one sensor as the accessory is mounted to the electronic device, identify an orientation in which the accessory is mounted to the electronic device, and output, via the display, content corresponding to the identification information and the mounted orientation.

Abstract: An electronic device may comprise: a first housing; a second housing movable relative to the first housing; a display including a display area configured to expand or contract according to the movement of the second housing; and at least one processor, comprising processing circuitry. While displaying a first portion of content in the display area, at least one processor, individually and/or collectively, is configured to: identify an expansion of the display area visible to the outside of the first housing; based on identifying the expansion of the display area, identify attributes of the content displayed through the display area; and based on the attributes, control the electronic device to display a second portion connected to the first portion in the content along with the first portion in the expanded display area.

Abstract: An electronic device is provided.

Abstract: An electronic device including a flexible display and a method of transitioning a first execution screen of a first application from one screen area of the flexible display to a second screen area are described. The first area may have a first screen ratio, whereas the second area may have a second screen ratio. The transition may be based on a folded/unfolded state of the electronic device. The transition may be triggered based on switching to/from a folded state. Several other screen areas may be used for additional transitions and provide visual effects to provide a seamless user experience through such transitions.

Abstract: A storage medium that stores commands, the commands being configured to enable at least one processor of an electronic device to perform at least one operation when executed by the at least one processor is provided. The at least one operation comprises identifying a remaining amount of a battery of the electronic device and a power consumption rate of the electronic device, and controlling, based on the remaining amount of battery and the power consumption rate, a driving circuit of the electronic device to switch a display of the electronic device from a first state to a second state, wherein a first area of the display is exposed in the first state, the first area including a second area and a third area and wherein the second area is exposed and the third area is not exposed in the second state.

Abstract: An electronic device is provided. The electronic device includes a display including a main display area and at least one expansion display area expandable from the main display area, a communication module, and a processor, wherein the processor is configured to execute an application of the electronic device in a first state in which the display is not expanded or in a second state in which the display is expanded, display first content on the display, establish a connection with an external device, receive a context generated from the external device, when the context is received, determine a position to display second content related to the context, from among the main display area or the at least one expansion display area, based on a type of the first content and whether the display is in the first state or the second state, and display the second content at the determined position.

Abstract: The present specification generally relates an aliphatic polyester material and a process for converting said aliphatic polyester material into a textile that is preferable for use as an artificial leather substrate.

Abstract: An electronic device is provided. The electronic device includes a display including a main display area and at least one expansion display area expandable from the main display area, a communication module, and a processor, wherein the processor is configured to execute an application of the electronic device in a first state in which the display is not expanded or in a second state in which the display is expanded, display first content on the display, establish a connection with an external device, receive a context generated from the external device, when the context is received, determine a position to display second content related to the context, from among the main display area or the at least one expansion display area, based on a type of the first content and whether the display is in the first state or the second state, and display the second content at the determined position.

Abstract: An electronic device is provided. The electronic device includes a display including a main display area and at least one expansion display area expandable from the main display area, a communication module, and a processor, wherein the processor is configured to execute an application of the electronic device in a first state in which the display is not expanded or in a second state in which the display is expanded, display first content on the display, establish a connection with an external device, receive a context generated from the external device, when the context is received, determine a position to display second content related to the context, from among the main display area or the at least one expansion display area, based on a type of the first content and whether the display is in the first state or the second state, and display the second content at the determined position.

Abstract: The present specification generally relates to a composition for the manufacture of ocean degradable, bio-degradable, bio-compostable, biocompatible articles that contain a bio-based thermoplastic component. More specifically, the present invention relates to an aliphatic polyester resin composition comprising: (i) a polyhydroxyalkanoate (PHA) in the range of 100%-51% by weight in combination with (ii) a semiconductor in the range of 0%-49% by weight, and (iii) an additive in the range of 0% to about 75% by weight of the total composition; and the subsequent manufacture of articles formed using the aliphatic polyester resin composition.

Abstract: A storage medium that stores commands, the commands being configured to enable at least one processor of an electronic device to perform at least one operation when executed by the at least one processor is provided. The at least one operation comprises identifying a remaining amount of a battery of the electronic device and a power consumption rate of the electronic device, and controlling, based on the remaining amount of battery and the power consumption rate, a driving circuit of the electronic device to switch a display of the electronic device from a first state to a second state, wherein a first area of the display is exposed in the first state, the first area including a second area and a third area and wherein the second area is exposed and the third area is not exposed in the second state.

Abstract: A method for treating cancer in a patient who is resistant to a protein kinase inhibitor, administering an anticancer agent containing, as an active ingredient, a thienopyridine derivative compound or a pharmaceutically acceptable salt thereof is disclosed. Here, the patient may carry active RON. In addition, the patient may carry normal KRAS gene. In addition, the anticancer agent may be applied to a patient who is resistant to an EGFR inhibitor. In particular, the anticancer agent may be usefully used to treat a patient who is resistant to the therapeutic agent cetuximab.

Abstract: The present disclosure relates to heterocyclic compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis.

Abstract: An electronic device including a flexible display and a method of transitioning a first execution screen of a first application from one screen area of the flexible display to a second screen area are described. The first area may have a first screen ratio, whereas the second area may have a second screen ratio. The transition may be based on a folded/unfolded state of the electronic device. The transition may be triggered based on switching to/from a folded state. Several other screen areas may be used for additional transitions and provide visual effects to provide a seamless user experience through such transitions.

Abstract: A computer analyzes blockchain ledger content. The computer receives a set of attributes associated with a predetermined entity and applies a one-way function to the attributes, generating an inquiry hash. The computer receives access to a blockchain ledger that includes a report with at least one report hash associated with an attribute of a report entity. The computer searches the report using the inquiry hash as a search key. The computer generates a list of candidate reports containing hashes that matches the inquiry hash. The computer assigns an entity matching confidence rating to candidate reports based, at least in part, on a predetermined identification utility value associated with each inquiry hash matched. The identification utility value indicates a likelihood that the report entity is the predetermined entity. The computer generates a list of high assurance reports having entity matching confidence ratings above a predetermined assurance threshold.

Abstract: A thienopyridine derivative compound represented by Formula 1 or pharmaceutically acceptable salts thereof have an excellent inhibitory effect on protein kinase activity, and accordingly, pharmaceutical compositions containing the thienopyridine compound can be usefully used for the prevention or treatment of a disease associated with the activity of a protein kinase.

Abstract: A thienopyridine derivative compound of Formula 1 or pharmaceutically acceptable salts thereof have an excellent inhibitory effect on protein kinase activity, and accordingly, pharmaceutical compositions containing the thienopyridine compound can be usefully used for the prevention or treatment of a disease associated with the activity of a protein kinase. Therefore, a use of the compound or a pharmaceutically acceptable salt thereof in treating a disease associated with an activity of a protein kinase in a subject in need thereof is disclosed.