Abstract: Systems, apparatuses, and methods for managing privacy of data are provided. The method includes providing at least one database containing user data, at least one processor in communication with the at least one database, a memory device including readable instructions, and at least one user device in communication with the at least one processor via a network connection; receiving at least one preference related to the user data; storing the at least one preference in the at least one database; and using the at least one preference to selectively control at least one non-verbal interaction with the at least one user device.

Abstract: The invention relates to peptide linkers and fusion proteins comprising linkers designed for optimizing the activity of the proteins comprised therein, and methods for using the same. The invention further relates to newly designed Cas12a-based adenine base editors.

Abstract: Systems, apparatuses, and methods for managing privacy of data are provided. The method includes providing at least one database containing user data, at least one processor in communication with the at least one database, a memory device including readable instructions, and at least one user device in communication with the at least one processor via a network connection; receiving at least one preference related to the user data; storing the at least one preference in the at least one database; and using the at least one preference to prevent at least one interaction with the at least one user device.

Abstract: Systems, apparatuses, and methods for managing privacy of data are provided. The method includes providing at least one database containing user data, at least one processor in communication with the at least one database, a memory device including readable instructions, and at least one user device in communication with the at least one processor via a network connection; receiving at least one preference related to the user data; storing the at least one preference in the at least one database; and using the at least one preference to selectively control at least one verbal interaction with the at least one user device.

Abstract: The present disclosure relates to an additive manufacturing system for forming a part using a powder material. In one embodiment the system makes use of a primary heat generating subsystem to generate a fusing beam for heating and fusing at least one of select portions of a powder layer, or an entire area of a powder layer, deposited on a build plate. The system also incorporates a beam steering subsystem for steering the fusing beam over the powder layer. A supplemental heating subsystem is used to generate a wide area beam to heat a portion of the powder layer either prior to fusing, along with the fusing operation, or subsequent to fusing of the powder with the fusing beam. The wide area beam has an intensity which is insufficient to fuse the powder, and alters a microstructure of the powder layer as the powder layer is at least one of fused or as it cools, to thus relieve stress in the part.

Abstract: A surgical implant and a surgical kit. The surgical implant has a body having at least one interior surface, the body forming a peripheral support for the implant. The surgical implant has a porous insert comprised of a porous material, having at least one axially-extending hole, and attached to the body along the at least one interior surface such that the porous material extends across a height of the body. The porous insert has a locking mechanism formed in the porous insert or extending from the porous insert, the locking mechanism minimizing movement of the porous insert from within the body. The surgical kit includes the surgical implant and an intervertebral insertion device.

Abstract: A planar floor covering is formed having a top face and a bottom face opposite the top face, a length, a width perpendicular to the length, a top surface, a bottom surface opposite the top surface, a height between the top surface and the bottom surface, and physical properties or characteristics that vary across at least one of the length, the width and the height. The physical properties or characteristics include material composition, weight, density, directionality, stiffness, compressibility, elasticity and thickness.

Abstract: A nanofluid laser entrainment additive manufacturing apparatus, system and method including a substrate, a dilute nanofluid of inert gas suspended nanoparticles on the substrate, a focused energy beam that irradiates the nanoparticles to selectively melt the nanoparticles, and a raster system that raster scans the focused energy beam across the inert gas suspended nanoparticles to create predetermined shapes by additive manufacturing.

Abstract: Resin dissolved or suspended in liquid is applied to a greige fabric formed with finer denier yarns forming surface loops before the fabric is bulked and after the liquid has been removed by low-temperature drying. The dried fabric is then bulked at a higher temperature setting the resin, resulting in superior loop tip resilience, and superior surface durability. Bulking and simultaneous resin setting optionally includes shrinking in area by 10-20%. Print appearance retention is also superior when printing follows bulking and setting of the resin.

Abstract: Described herein are engineered proteins and methods of use of such proteins. Also described herein are complexes, compositions, and systems including engineered proteins of the present invention, each of which may be used for modifying and/or editing a target nucleic acid. An engineered protein of the present invention may be an enzyme and/or may be an RNA-guided DNA-binding protein.

Abstract: Techniques are described for using a supplemental data layer of a real time payments channel to send data. For example, an entity may request a transaction with another entity, and the transaction may be performed using a channel that includes a supplemental data layer. Supplemental data, in addition to the data for the transaction itself, may be communicated using the supplemental data layer to entities involved in the transaction, and/or to third parties. The supplemental data may be sent in real time with respect to the sending of the data for the transaction. In some instances, supplemental data layer is present in one or both directions in the two-way communications between the entities involved in the transaction. The supplemental data layer can be leveraged to provide additional information and/or services to a user involved in the transaction.

Abstract: Systems, devices, and methods described herein monitor when the fluid path of a medication in a parenteral medication delivery device is established or interrupted.

Abstract: The present disclosure relates to devices that include a perovskite, where, when a first condition is met, at least a portion of the perovskite is in a first phase that substantially transmits light, when a second condition is met, at least a portion of the perovskite is in a second phase that substantially absorbs light, and the perovskite is reversibly switchable between the first phase and the second phase by reversibly switching between the first condition and the second condition.

Abstract: The present disclosure relates to a device that includes a perovskite layer; and a first layer that includes a molecule having a structure according to formula (I) Wherein the perovskite layer and the first layer are in physical contact, n is between 1 and 10, inclusively, R1 includes at least one of hydrogen, a first alkyl group, a first alkoxy group, and/or a first halogen, R2 includes at least one of hydrogen, a second alkyl group, a second alkoxy group, and/or a second halogen, R1 is bonded to aromatic ring (A) at carbon atom (1), carbon atom (2), carbon atom (3), or carbon atom (4), R2 is bonded to aromatic ring (B) at carbon atom (5), carbon atom (6), carbon atom (7), or carbon atom (8), and R1 and R2 are the same or different.

Abstract: A surgical implant and a surgical kit. The surgical implant has a body portion comprising a first hole formed in an exterior surface of the body portion, a second hole adjacent the first hole, and at least one through-hole within the body portion and extending entirely thought a depth of the body portion extending entirely thought a depth of the body portion. The implant has a central opening abutting the body portion and extending through the body portion. The first hole has a first sidewall and a first cavity in the body portion, the second hole has a second sidewall and a second cavity in the body portion, and the first cavity and the second cavity have an interconnected opening there between. The surgical kit includes the surgical implant and an intervertebral insertion device.

Abstract: Systems, devices, and methods described herein indirectly monitor a state of fluid flow by monitoring a state of connection of a medication delivery device. The system includes an enclosure, a contact sensor, and a controller. The enclosure can attach around at least a portion of an outer surface of the medication delivery device to enclose at least a portion of the outer surface therein. The contact sensor and controller are enclosed within the enclosure. The contact sensor can monitor a state of electrical connection. The controller is in communication with the contact sensor and can relay the state of electrical connection. The state of connection of the contact sensor corresponds to the state of connection of the medication delivery device.

Abstract: Computing devices, systems, and methods for automatically prompting a foreign currency transaction by detecting a trip end condition associated with a registered user with respect to travel to a foreign location associated with a foreign currency. The methods and system may further determine that the registered user has a remaining foreign currency balance, and, as a result, may identify and send to the registered user's mobile device at least one option for using the remaining foreign currency balance. The at least one option may be a merchant offer from a merchant located in the area of the mobile device or may include an option to exchange the foreign currency for another currency. The trip end condition may be detected by determining that the registered user and/or user's mobile device is at an international departure location. The currency exchange may be with another registered user.

Abstract: This invention relates to compositions and methods for modifying an endogenous nucleic acid encoding a Phytochrome A (PHYA) polypeptide for suppression of the shade avoidance response in plants. The invention further relates to plants produced using the methods and compositions of the invention.

Abstract: A surgical implant and a surgical kit. The surgical implant has a body having at least one interior surface, the body forming a peripheral support for the implant. The surgical implant has a porous insert comprised of a porous material, having at least one axially-extending hole, and attached to the body along the at least one interior surface such that the porous material extends across a height of the body. The porous insert has a locking mechanism formed in the porous insert or extending from the porous insert, the locking mechanism minimizing movement of the porous insert from within the body. The surgical kit includes the surgical implant and an intervertebral insertion device.

Abstract: An expandable intervertebral implant having an upper body portion, a lower body portion opposite the upper body portion, a wedge member connecting the upper body portion to the lower body portion, a nose member having a tapered distal end and a proximal end opposite the distal end, and an actuator disposed between the nose member and the wedge member, for translation of the wedge member along a longitudinal axis of the implant. A pin connects to the actuator for positioning the nose member relative to the actuator. Translation of the wedge member along the longitudinal axis of the implant displaces the upper body portion and the lower body portion away from each other, thereby expanding the intervertebral implant.