Abstract: A heat sink comprising a heat spreader (2) made from synthetic diamond and having a front surface for mounting one or more components to be cooled like a laser disc (8) and a rear surface for direct fluid cooling (10). A plurality of ribs (4,7) is bonded to the rear surface of the heat spreader (2) to stiffen the heat spreader. Both the heat spreader and the plurality of ribs are formed of synthetic diamond material. The ribs (4,7) may be fixed to the heat spreader by braze bonds (6).

Abstract: A rail assembly includes a track assembly with a retaining lip and a carriage assembly that is received within the track assembly. The carriage assembly includes a body portion, an exterior surface of the body portion, and a retaining bracket fastened to the exterior surface. The retaining bracket extends outwardly from the point at which the retaining bracket is fastened to the exterior surface. The retaining bracket defines a notch that receives the retaining lip of the track assembly.

Abstract: A data hub for servicing data hub dependent data consumers includes a persistent storage and a data validator. The persistent storage stores validated data. The data validator obtains a data validation request; in response to obtaining the data validation request: imports data from a data aggregator to obtain the validated data; performs a continuity analysis of the validated data to generate a data deviation report; and provides a portion of the validated data to one of the data hub dependent data consumers.

Abstract: A negative optical power electrowetting optical device is provided. The negative optical power electrowetting optical device includes: a non-conductive liquid having a refractive index; a conductive liquid having a second refractive index; and a dielectric surface in contact with both the conductive and non-conductive liquids. The refractive index of the non-conductive liquid is less than the second refractive index of the conductive liquid and wherein the conductive liquid is immiscible with the non-conductive liquid.

Abstract: Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

Abstract: A property vector representing extractable measurable properties, such as musical properties, of a file is mapped to semantic properties for the file. This is achieved by using artificial neural networks “ANNs” in which weights and biases are trained to align a distance dissimilarity measure in property space for pairwise comparative files back towards a corresponding semantic distance dissimilarity measure in semantic space for those same files. The result is that, once optimised, the ANNs can process any file, parsed with those properties, to identify other files sharing common traits reflective of emotional-perception, thereby rendering a more liable and true-to-life result of similarity/dissimilarity. This contrasts with simply training a neural network to consider extractable measurable properties that, in isolation, do not provide a reliable contextual relationship into the real-world.

Abstract: Disclosed herein are compounds of formula (I) and therapeutic methods of treatment with compounds of formula (I), wherein L1, L2, L4, R1, R4, R5, R6, and s are as defined in the specification. Compounds of formula (I) are EP4 agonists useful in the treatment of glaucoma, neuropathic pain, and related disorders.

Abstract: A system is provided to secure a pair of glasses to a hat, the system including a hatband insert configured to be inserted in a hatband of a hat, one or more hatband magnetic members configured to be selectively attachable to a plurality of locations of the hatband insert, and one or more glasses magnetic members configured to be attached to each temple of a pair of glasses, wherein the one or more hatband magnetic members and the one or more glasses magnetic members are configured to be magnetically attached to selectively secure the glasses to the hat.

Abstract: Described herein is a system for device arbitration using acoustic characteristics of a physical space, such as a user's household. The system generates a matrix of inter-device attenuation factors. The inter-device attenuation factors are determined using the attenuation experienced by a first device versus the attenuation experienced by a second device. Once the matrix is generated, an attenuation vector representing the attenuation corresponding to an input audio signal is determined and compared to the matrix. Based on the comparison, the system selects a device for further processing.

Abstract: There is provided a data processing apparatus comprising table circuitry to store a table that indicates, for a program counter value of an instruction that performs a memory access operation at a memory address, one or more offsets of the memory address and an associated confidence for each of the one or more offsets. Prefetch circuitry prefetches data based on each of the offsets in dependence on the associated confidence. Each of the offsets of the memory address is dynamically determined.

Abstract: The present invention provides a method of inhibiting an effect of a noxious insult, such as an ischaemia-reperfusion injury, to an organ of a subject, the method comprising administering zinc, or a pharmaceutically acceptable salt thereof, such as Zinc Chloride, to a subject in need thereof, wherein the zinc, or the pharmaceutically acceptable salt thereof, is administered to the subject intravascularly in an amount that is sufficient to inhibit the effect of the noxious insult.

Abstract: Disclosed herein are several embodiments of a negative pressure appliance and methods of using the same in the treatment of wounds. Some embodiments are directed to improved fluidic connectors or suction adapters for connecting to a wound site, for example using softer, kink-free conformable suction adapters.

Abstract: An automatic string weaving system for weaving strings for a stringed sports racquet, comprising a weave assembly that the strings for the stringed sports racquet are weaved through; and an automated string feeder assembly to automatically weave the strings for the stringed sports racquet through the weave assembly.

Abstract: A polycrystalline CVD synthetic diamond material is provided that has an average thermal conductivity at room temperature through a thickness of the polycrystalline CVD synthetic diamond material of between 1700 and 2400 Wm?1K?1, a thickness of at least 2.5 mm and a visible transmittance through the thickness of the polycrystalline CVD synthetic diamond of at least 25%. A wafer comprising the material is also provided, wherein at least 70% of a total area of the wafer has the properties of the polycrystalline CVD synthetic diamond material. A method for fabricating the wafer is also disclosed.

Abstract: The present approach improves the query performance of a database in a manner that is transparent to a user. In one aspect, this approach creates separate partition tables that are not directly accessible to a user of the database. A client-facing aspect of the database is a logical model which may correspond to a single, main table with which the user interacts. Thus, queries or operations may be generated on the client side in the context of the logical model. A database or query layer can then, transparent to the user, translate the user generated requests into query language that addresses the proper partitions to generate a result set or otherwise perform a database operation.

Abstract: A method is disclosed utilizing the administration of extended release L-tri-iodothyronine in order to ameliorate insulin resistance. In other embodiments extended release L-tri-iodothyronine is combined with a biguanide and/or a thiazolidinedione and/or an inhibitor of the endoplasmic reticulum integrated stress response to provide a multi-targeted and synergistic approach to ameliorate insulin resistance.

Abstract: A system for capturing carbon dioxide in flue gas includes a fuel cell assembly including at least one fuel cell including a cathode portion configured to receive, as cathode inlet gas, the flue gas generated by the flue gas generating device or a derivative thereof, and to output cathode exhaust gas and an anode portion configure to receive an anode inlet gas and to output anode exhaust gas, a fuel cell assembly voltage monitor configured to measure a voltage across the fuel cell assembly, and a controller configured to receive the measured voltage across the fuel cell assembly from the fuel cell assembly voltage monitor, determine an estimated carbon dioxide utilization of the fuel cell assembly based on the measured voltage across the fuel cell assembly, and reduce the carbon dioxide utilization of the fuel cell assembly when the determined estimated carbon dioxide utilization is above a predetermined threshold utilization.

Abstract: A vehicle seating assembly includes a seatback having a base. A reclining portion is pivotably coupled to the base at first and second attachment points and includes first and second longitudinal members. A panel is disposed between the first and second longitudinal members. A cross member extends between the first and second attachment points. A bracket is coupled to the panel and is disposed between the panel and the cross member.

Abstract: A hybrid diffractive and refractive contact lens, and methods of treatment of optical conditions using such a lens. A first lens portion is formed from a first lens material having a first index of refraction and includes at least one diffractive optical element. A second lens portion is formed from a second lens material having a second index of refraction different from the first index of refraction. The diffractive optical element may be embedded within the second lens portion to provide comfort, tear film stability, and optical performance.