Abstract: Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter di of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.

Abstract: The invention provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections, particularly infections caused by herpesviruses.

Abstract: Systems and techniques may be used for multiple biometric data authentication. An example technique may include receiving first biometric data and second biometric data, optionally combining the first biometric data and the second biometric data into combined biometric data, and comparing the first and second or the combined biometric data to stored biometric reference data associated with an account of a user to generate a similarity score. The example technique may include determining whether the similarity score exceeds a threshold value, and in response to determining that the similarity score exceeds the threshold value, outputting an indication.

Abstract: A device may include a housing having a bottom portion. The device may include one or more plugs, wherein the bottom portion of the housing includes a threaded portion configured to receive a cap, and an aperture configured to receive a power cable having a first diameter, wherein the threaded portion includes a compression tab configured to compress the power cable as the threaded portion receives the cap.

Abstract: An umbilical arterial catherization device comprising a brace and a dilator. The brace has a body for supporting and stabilizing an umbilical cord end. The body may have resilient foam for grasping the umbilical cord, and may include a strap operable to secure part of the body to itself, after being wrapped around the umbilical cord. The dilator has a hook for engaging an open end of an arterial lumen, and a catch operable to fix the dilator to the brace in a position for dilating the arterial lumen. Both hands may be used to place the dilator while the device serves to stabilize and support the umbilical cord without use of the hands. The device may include a lighting element for illuminating the end of the umbilical cord to aid in visualization of the arterial lumen and facilitate proper placement of the catch within the arterial lumen.

Abstract: Techniques are provided for orienting a digital human towards an isolated human speaker. One method comprises obtaining coordinates associated with a human speaker; storing the coordinates as a variable in a memory of a multi-dimensional graphics engine; instantiating a multi-dimensional plane within the multi-dimensional graphics engine; positioning a multi-dimensional shape in the multi-dimensional plane based on the stored coordinates; and binding a digital human to the multi-dimensional shape to orient the digital human towards a position of the multi-dimensional shape. The coordinates may be obtained by comparing text obtained from one or more video streams to text obtained from one or more audio signals.

Abstract: The invention relates to norcoclaurine synthases and substrate binding sites having one or more site-specific mutation which increase the activity, when compared to the wild type synthase, of the condensation of 4-HPAA and dopamine to (S)-norcoclaurine and/or 3,4-DhPAA and dopamine to (S)-norlaudanosoline. The inventors both identified specific mutations corresponding to at position 73, 75, 77, 82, 99, 114, 141, 142, 147, 152, 174 and/or 178 in the count according to SEQ ID No: 1, and sites corresponding to the binding domains defined in SEQ IN NO: 4 and 5, where the mutated increase of the activity may be positioned within these norcoclaurine synthases. These domains are conserved regions.

Abstract: In various embodiments there is a method for camera localization within a scene. An image of a scene captured by the camera is input to a machine learning model, which has been trained for the particular scene to detect a plurality of 3D scene landmarks. The 3D scene landmarks are pre-specified in a pre-built map of the scene. The machine learning model outputs a plurality of predictions, each prediction comprising: either a 2D location in the image which is predicted to depict one of the 3D scene landmarks, or a 3D bearing vector, being a vector originating at the camera and pointing towards a predicted 3D location of one of the 3D scene landmarks. Using the predictions, an estimate of a position and orientation of the camera in the pre-built map of the scene is computed.

Abstract: A seat assembly includes a seat portion having a frame assembly, a carrier assembly and a displaceable platform operably coupled to the carrier assembly. The displaceable platform is operable between a use position and a deployed position. A retraction mechanism includes a first bracket operably coupled to the frame assembly, and a second bracket operably coupled to the displaceable platform. The first and second brackets are interconnected by an actuator that is operable between at-rest and actuated positions. The second bracket moves from a first position to a second position as the actuator moves from the at-rest position to the actuated position. At least one tether member is operably coupled to the first bracket and includes a body portion interlaced between the first and second brackets of the retraction mechanism.

Abstract: A thermally reworkable adhesive includes at least one di-epoxide, at least one diamine that is reactive with the at least one di-epoxide, at least one additive that is miscible, but not reactive, with the at least one di-epoxide and/or the at least one diamine. Reaction of the at least one di-epoxide and the at least one diamine forms a crosslinked polymer network and the at least one additive offsets the stoichiometry of the crosslinked polymer network by 5-50%. The offset crosslinked polymer network forms the thermally reworkable adhesive that once cured, at a temperature in the range of 20-200° C., can be de-bonded from a device to which it is attached at a temperature in the range of 50-200° C.

Abstract: A system includes a pressure exchanger (PX) including a housing and configured to exchange pressure between a first fluid and a second fluid. The system further includes a bearing valve fluidly coupled to the housing of the PX and configured to provide the first fluid to the housing. The system further includes a controller to cause a first adjustment of a first flowrate of the first fluid into the PX based on a target flowrate of first fluid into the PX and the first flowrate. The controller is further to cause a second adjustment of a second flowrate of the second fluid into the PX based on the first flowrate and the second flowrate.

Abstract: Methods, systems, and non-transitory computer-readable media are configured to perform operations comprising determining a rescue lane scenario for an environment, determining an amount of lateral bias for a vehicle, and generating planning and control data for the vehicle to laterally bias based on the amount of lateral bias.

Abstract: Described are acoustic absorber materials with high acoustic attenuation and high thermal conductivity comprising an inorganic, porous foam and an absorbing material within at least a portion of the pores of the foam, ultrasound transducers and devices including the same, as well as methods of making the materials.

Abstract: A drug delivery device includes a housing, an injection assembly at least partially disposed in the housing, a shield, and a drive assembly at least partially disposed in the housing and coupled with the injection assembly and the shield. The shield has an extended position where at least a proximal end thereof extends a distance beyond a proximal end of the housing. The injection assembly includes a needle or cannula having an endpoint. Upon moving the shield axially towards the distal end of the housing a predetermined distance, a retraction profile commences whereby the drive assembly administers a medicament via the injection assembly. A peak resistance force is exerted within approximately the first 12 mm of axial movement of the shield.

Abstract: A backflow preventer for preventing a reverse flow of water in a plumbing system including a body having an inlet and an outlet. The body forms an intermediate zone between the inlet and outlet. An inlet check valve prevents the reverse flow of water from the intermediate zone through the inlet. An outlet check valve prevents the flow of water from the outlet into the intermediate zone. An inlet pressure sensor, an intermediate pressure sensor and an outlet pressure sensor provide readings for the respective zones. A controller monitors a pressure differential between the outlet pressure zone and the intermediate pressure zone to compare the pressure differential to a pre-set range. The controller generates a warning/error message when the pressure differential is outside the pre-set range. The controller can also monitor an inlet pressure in the inlet zone to generate a message if the inlet pressure varies inappropriately.

Abstract: A package in which an onboard computing system and a plurality of sensor devices are embedded. The package includes a plurality of cameras that are positioned against sidewalls of the package in order to capture image data of the external environment. When the computing system determines the package has arrived at a predesignated set of coordinates corresponding to a target property for which an appraisal is to be performed, the cameras are activated and begin collecting image data. The image data is transmitted to a remote server which will store the image data for review by insurance personnel.

Abstract: The present disclosure provides a clamp mechanism to secure a temperature sensor to a plumbing fixture. The clamp includes a first semicircular portion and a first sensor housing lobe; a second semicircular portion and a second sensor housing lobe; wherein the first and second sensor housing lobes being hingedly coupled together and defining a first bore between the first and second semicircular portions to fit around pipe structures and around a test cock, and wherein the first and second sensor housing lobes defining a second bore between the first and second sensor housing lobes to house a temperature sensor configured to generate temperature sensor data indicative of an ambient temperature around the plumbing fixture.

Abstract: A wireless sensor platform design and a single walled carbon nanotube/ionic liquid-based chemidosimeter system can incorporated into a highly sensitive and selective chemical hazard badge that can dosimetrically detect an analyte down to a sub parts-per-million concentration.

Abstract: The application provides a light expander/contractor device and method of using same, the light expander/contractor device comprising: a faceted quartz structure comprising a lateral surface communicating with a light processing surface at one end and communicating with a planar surface at an opposed end; the light processing surface comprising an initial surface extending from the lateral surface substantially parallel to the planar surface and having a distal end spaced from the lateral surface, the light processing surface further comprising multiple levels of facets comprising quartz-air interfaces: each level of facets comprising (a) a proximal facet surface relative to the lateral surface, the proximal facet surface extending away from the initial surface and toward the lateral surface at a 45° angle relative to the initial surface to communicate with (b) a facet planar surface spaced apart from and parallel to the initial surface to communicate with (c) a distal facet surface adjacent and substantially

Abstract: Interesting features of an object within a physical environment are identified from a video of the physical environment. A model of the object is obtained, the model includes dimensions of the object. A first array is maintained with the pixel coordinates of the identified features within the video. A second array is maintained with the dimensions of the features obtained from the model. A processing framework is provided for using the first and second arrays and estimating, updating, and tracking the anchor pose in the physical environment within the video along with any AR generated objects placed in the video. The framework provided to an Augmented Reality (AR) app to initiate an AR session and to maintain the session.