Abstract: An orthopedic implant includes a bridge having a central axis. In addition, the orthopedic implant includes a plurality of torsion regions coupled to the bridge. Each torsion region has a longitudinal axis. Further, the orthopedic implant includes a plurality of legs. Each leg is coupled to and extends from one of the plurality of torsion regions. Each leg is configured to rotate about the longitudinal axis of the corresponding torsion region between a first position and a second position that is angularly displaced relative to the first position about the longitudinal axis of the corresponding torsion region to induce an elastic torsional stress in the corresponding torsion region. Each leg is biased from the second position toward the first position by the elastic torsional stress in the corresponding torsion region when the leg is in the second position.

Abstract: A damping control system for a vehicle having a suspension located between a plurality of ground engaging members and a vehicle frame includes at least one adjustable shock absorber having an adjustable damping profile.

Abstract: A vertical bundle air-cooled heat exchanger, a finned tube assembly for an air cooled condenser and method for forming the same, and a system for removing thermal energy generated by radioactive materials. In one aspect, an air cooled condenser sized for industrial and commercial application includes an inlet steam distribution header for conveying steam, a condensate outlet header for conveying condensate, an array of tube bundles each having a plurality of finned tube assemblies having a bare steel tube with an exposed outer surface and a set of aluminum fins brazed directly onto the tube by a brazing filler metal. The steel tubes may be spaced apart by the aluminum fins and have an inlet end fluidly coupled to the inlet steam distribution header and an outlet end fluidly coupled to the outlet header. A forced draft fan may be arranged to blow air through the tube bundles.

Abstract: A connection device for fastening two expanded cellular confinement structures includes: an insertion member; an integral shank extending perpendicular from the insertion member; and an integral handle member extending perpendicular from the shank at an end of the shank remote from the insertion member. One or more barbs may project from the insertion member. The device can have a washer section between the handle member and insertion member. The handle can be curved, or it can be in the shape of a polygon.

Abstract: The present invention provides formulations of 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile (compound I) and methods for treating ocular surface pain by administering such formulations. The present invention also provides methods for treating dry eye disease and ocular hyperemia by administering formulations of 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile.

Abstract: The present disclosure relates to heterobifunctional molecules, referred to as cytotoxicity targeting chimeras (CyTaCs) or antibody recruiting molecules (ARMs) that are able to simultaneously bind a target cell-surface protein as well as an exogenous antibody protein. The present disclosure also relates to agents capable of binding to a receptor on a surface of a pathogenic cell and inducing the depletion of the pathogenic cell in a subject for use in the treatment of cancer, inflammatory diseases, autoimmune diseases, viral infection, or bacterial infection.

Abstract: An example orthopedic implant includes a bridge, a plurality of torsion regions coupled to the bridge, and a plurality of legs coupled to and extending from the plurality of torsion regions. The plurality of legs are configured to transition between a first position and a second position, and in the second position, the plurality of legs are angularly displaced relative to the first position. In addition, the legs are biased toward the first position by elastic torsional stresses in the plurality of torsion regions when the legs are in the second position.

Abstract: Typical chemical vapor deposition (CVD) systems are unable to analyze a sample during CVD fabrication. A system and method for performing material deposition and in-situ analysis of a sample during CVD synthesis is described. The system includes a deposition chamber having an outer chamber wall surrounding a chamber volume and an inner sleeve disposed inside of the chamber volume with a buffer region between the outer chamber wall and the inner sleeve. A sample mount is disposed in the deposition volume to support a position and orientation of a sample in the deposition volume during CVD. Gas inlets and gas outlets are in fluid communication with the deposition chamber to respectively allow fluid to flow into, and out of, the deposition chamber. A thermal radiation source provides thermal radiation along a deposition axis to the sample disposed in the deposition volume.

Abstract: A liquid distribution system for a crop sprayer having a laterally extendable boom includes a first product tank configured to contain a first liquid, one or more auxiliary product tank(s) configured to contain an additional liquid(s), a first fluid power source in fluid communication with the first product tank, a pressurized air source in fluid communication with the auxiliary product tank, at least one mixing valve carried by the boom, and at least one nozzle carried by the boom and configured to receive mixed liquid from the at least one mixing valve. The mixing valve(s) are configured to receive the first liquid and the additional liquid(s), and form the mixed liquid. Crop sprayers and related methods are also disclosed.

Abstract: A dessert holder that enables a consumer to hold or grasp a banana (frozen or non-frozen) in such a way that various toppings, garnishes, trimmings, etc. that have been added to the banana do not readily spill over onto the consumer's hands. The dessert holder may also act as a thermal insulator so that the consumer is able to easily hold and eat a cold, frozen banana without making their hands uncomfortable. In one example, the dessert holder includes a main body section that is in the shape of a part of a banana and has first and second ends, as well as a flange section that is connected to the main body section at the second end, which is open to allow the banana to be inserted. The dessert holder may be made from an injection-moldable, food grade (e.g., FDA food grade), thermoplastic elastomer (TPE) or thermoplastic rubber.

Abstract: A vertical bundle air-cooled heat exchanger, a finned tube assembly for an air cooled condenser and method for forming the same, and a system for removing thermal energy generated by radioactive materials. In one aspect, an air cooled condenser sized for industrial and commercial application includes an inlet steam distribution header for conveying steam, a condensate outlet header for conveying condensate, an array of tube bundles each having a plurality of finned tube assemblies having a bare steel tube with an exposed outer surface and a set of aluminum fins brazed directly onto the tube by a brazing filler metal. The steel tubes may be spaced apart by the aluminum fins and have an inlet end fluidly coupled to the inlet steam distribution header and an outlet end fluidly coupled to the outlet header. A forced draft fan may be arranged to blow air through the tube bundles.

Abstract: The present disclosure relates to heterobifunctional molecules, referred to as cytotoxicity targeting chimeras (CyTaCs) or antibody recruiting molecules (ARMs) that are able to simultaneously bind a target cell-surface protein as well as an exogenous antibody protein. The present disclosure also relates to agents capable of binding to a receptor on a surface of a pathogenic cell and inducing the depletion of the pathogenic cell in a subject for use in the treatment of cancer, inflammatory diseases, autoimmune diseases, viral infection, or bacterial infection.

Abstract: A product comprises a thin film comprising metal nanostructures in an optically transparent polymer, wherein a loading of the metal nanostructures ranges from 5-50 wt % and having a sheet resistance less than 20 Ohm/sq. Related devices and methods are also disclosed.

Abstract: Image Signal Processing (ISP) optimization framework for computer vision applications is disclosed. The tuning of the ISP is performed automatically and presented as a nonlinear multi-objective optimization problem, followed by solving the problem using an evolutionary stochastic solver. An improved ISP of the embodiments of the invention includes at least features of search space reduction for reducing a number of ISP configurations, remapping the generated population to the reduced search space via mirroring, and global optimization function processing, which allow tuning all the blocks of the ISP at the same time instead of the prior art tuning of each ISP block separately. Also shown that an ISP tuned for image quality performs inferior compared with an ISP trained for a specific downstream image recognition task.

Abstract: A method for managing location-based tasks for a location-aware vehicle, including: receiving a first request from a first device having a first user interface to create a first location-based task; creating a first location-based task based on the input received from the first device; storing the first location-based task in a task-service memory; associating the first location-based task with a first location; and associating the location-based task with the location-aware vehicle.

Abstract: A system that facilitates access control at venues through cohort affinity grouping. It verifies users' authenticity by comparing credentials stored in a database, then identifies related users based on social graph data, such as past attendance and social media activity. By determining correlation values among users, it forms cohorts associated with the venue's resources. Users select and join cohorts, and access rights are transmitted accordingly. A smart queue system triggers notifications for check-in, optimizing the process based on predefined intervals. Any member's check-in request triggers check-in for the entire cohort, streamlining entry. The system assigns queue numbers and notifies users of seating arrangements, fostering a cohesive user experience.

Abstract: A system is disclosed that monitors endpoints such as video cameras and audio devices for malfunction through a novel TDMA device allocation format. The system isolates and analyzes a set of groups of video streams in a rotating and recurring fashion and generates alerts and remedial commands based on the analysis. The system also provides endpoint management functions such as password analysis and firewall functions.

Abstract: The present disclosure relates to heterobifunctional molecules, referred to as cytotoxicity targeting chimeras (CyTaCs) or antibody recruiting molecules (ARMs) that are able to simultaneously bind a target cell-surface protein as well as an exogenous antibody protein. The present disclosure also relates to agents capable of binding to a receptor on a surface of a pathogenic cell and inducing the depletion of the pathogenic cell in a subject for use in the treatment of cancer, inflammatory diseases, autoimmune diseases, viral infection, or bacterial infection.