Abstract: The present invention relates to antibodies binding to IL13 and IL22. The invention provides novel multi-specific antibodies that bind to both IL13 and IL22 and compositions comprising an antibody that binds to IL13 and an antibody that binds to IL22. The invention further relates to therapeutic uses of the combination of anti-IL13 and anti-IL22 antibodies and multi-specific antibodies that bind to both IL13 and IL22.

Abstract: A method of accumulating a personalized list of products viewed by a user on different website domains includes providing a first embedded code on a first website domain and a second embedded code on a second website domain in which the first website domain is different from said second website domain. Each of the embedded codes allows a specified third party server to communicate interactively with the user. The method further includes automatically accumulating a personalized list of products viewed by the user in a database on the specified third party server, wherein the personalized list includes at least a first product and a second product, wherein the first product is on the first website domain and the second product is on the second website domain.

Abstract: A method for displaying archived exercise classes comprising displaying information about archived exercise classes that can be accessed by a first user via a computer network on a display screen at a first location, wherein the first user can select among a plurality of archived classes, outputting digital video and audio content comprising the selected archived class, detecting a performance parameter for the first user at a particular point in the selected class, displaying the performance parameter on the display screen, and displaying performance parameters from a second user at a second location on the display screen such that at least one of the performance parameters from the first user and at least one of the performance parameters from the second user at the same point in the class are presented for comparison.

Abstract: Systems and methods are provided for configuring automatic playback settings on a media playback device. A graphical user interface displays automatic playback settings and receives selections of customized settings for automatic playback. The settings can include context granularity for automatic playback, limiting autoplay to when the media playback device is connected to a wireless network, and activating an audible notification when automatic playback of media content is beginning. An initial queue of media content is selected for playback on the media playback device. The system ascertains whether autoplay is enabled for a particular situation. If autoplay is enabled, the system automatically generates a queue of media that is related to the initial queue and initiates playback on the media playback device after the initial queue concludes.

Abstract: A transmission includes an input shaft coupled to a prime mover, a countershaft, main shaft, and an output shaft, with gears between the countershaft and the main shaft. A shift actuator selectively couples the input shaft to the main shaft by rotatably coupling gears between the countershaft and the main shaft. The shift actuator is mounted on an exterior wall of a housing including the countershaft and the main shaft. A controller controls the shift actuator utilizing an actuating pulse and an opposing pulse.

Abstract: A refrigeration cycle device, comprising: a compressor configured to compress a refrigerant; an outdoor air heat exchanger configured to exchange heat between the refrigerant and outside air located outside a target space; an indoor air heat exchanger configured to exchange heat between the refrigerant and inside air located inside the target space; a water heat exchanger configured to exchange heat between the refrigerant and water; a four-way valve located between an indoor port on the indoor air heat exchanger, an outdoor port on the outdoor air heat exchanger, an input port on the compressor, and an output port on the compressor; a bypass refrigerant line connecting the indoor port to the outdoor port; and a controllable valve located on the bypass refrigerant line, the controllable valve being configured to have an open state that passes the refrigerant and a closed state that prohibits passage of the refrigerant.

Abstract: A connection device for fastening two expanded cellular confinement structures includes: an insertion member; an integral shank extending perpendicular from the insertion member; and an integral handle member extending perpendicular from the shank at an end of the shank remote from the insertion member. One or more barbs may project from the insertion member. The device can have a washer section between the handle member and insertion member. The handle can be curved, or it can be in the shape of a polygon.

Abstract: A damping control system for a vehicle having a suspension located between a plurality of ground engaging members and a vehicle frame includes at least one adjustable shock absorber having an adjustable damping profile.

Abstract: The embodiments provide a container of the type to hold fresh food or produce. Container has a base and a lid moveable with respect to the base between an open position and a closed position. The lid has a planar area. The base has a second planar area. In the closed position, the first planar and the second planar area include a substantially flat area suitable for receipt of an adhesive membrane, such as a self-adhesive label. The substantially flat area includes an edge of the first planar area and at least part of the second planar area.

Abstract: Methods and systems for implementing a Jupiter aerospace mission can enable delivery of a science payload to a Jupiter orbit on a direct Earth-to-Jupiter trajectory. Solar power and use of avionics also allow a fast assembly, integration, and test process compared to past outer Solar System missions. The spacecraft can include an aerodynamic forebody, a shell, and a thermal protection system. The spacecraft can manage the radiation environment, generate solar power, and return data to Earth with a robust radio-frequency (RF) amplification and antenna gain.

Abstract: A tabletop steam sterilizer system is housed within a tabletop cabinet housing having a water inlet that is adapted for connection to a municipal water supply, thus allowing its use anywhere that there is a standard water supply and without need of a distilled water supply. The tabletop steam sterilizer system includes a plurality of independently operable sterilizing chambers, each of which receives steam from a single steam generator. A single system controller provides for the on-demand sharing of system resources among the two sterilizing chambers. The tabletop steam sterilizer system also includes a water distiller system that receives water from the municipal or other non-distilled water supply, converts that municipal or other non-distilled water to distilled water, and supplies that distilled water to the sterilization chambers to carry out a sterilization cycle.

Abstract: A tabletop steam sterilizer system is housed within a tabletop cabinet housing having a water inlet that is adapted for connection to a municipal water supply, thus allowing its use anywhere that there is a standard water supply and without need of a distilled water supply. The tabletop steam sterilizer system includes at least one sterilizing chamber, although more than one independently operable sterilizing chamber may be provided. The tabletop steam sterilizer system also includes a water distiller system that receives water from the municipal or other non-distilled water supply, converts that municipal or other non-distilled water to distilled water, and supplies that distilled water to the sterilization chamber to carry out a sterilization cycle. Exhaust from the sterilization chamber may be recycled back to the distiller system for processing by the distiller system back into distilled water for subsequent sterilization cycles.

Abstract: Image Signal Processing (ISP) optimization framework for computer vision applications is disclosed. The tuning of the ISP is performed automatically and presented as a nonlinear multi-objective optimization problem, followed by solving the problem using an evolutionary stochastic solver. An improved ISP of the embodiments of the invention includes at least features of search space reduction for reducing a number of ISP configurations, remapping the generated population to the reduced search space via mirroring, and global optimization function processing, which allow tuning all the blocks of the ISP at the same time instead of the prior art tuning of each ISP block separately. Also shown that an ISP tuned for image quality performs inferior compared with an ISP trained for a specific downstream image recognition task.

Abstract: A system for storing gloves includes a storage box defining an internal cavity shaped to receive the gloves, a lid configured to cover the internal cavity, and a vacuum source configured to retain the gloves in the internal cavity when hands are removed from the gloves. A method includes opening a lid covering a storage box defining an internal cavity shaped to receive gloves, inserting hands covered by the gloves into the internal cavity, and applying a vacuum from a vacuum source to the internal cavity to remove the gloves from the hands.

Abstract: A transmission includes an input shaft coupled to a prime mover, a countershaft, main shaft, and an output shaft, with gears between the countershaft and the main shaft. A shift actuator selectively couples the input shaft to the main shaft by rotatably coupling gears between the countershaft and the main shaft. The shift actuator is mounted on an exterior wall of a housing including the countershaft and the main shaft. A controller controls the shift actuator utilizing an actuating pulse and an opposing pulse.

Abstract: A system for facilitating display misalignment correction includes one or more processors and one or more hardware storage devices storing instructions that are executable by the one or more processors to configure the system to (i) determine one or more user activity attributes associated with user operation of a stereoscopic display system, (ii) based on the one or more user activity attributes, determine one or more correction application attributes, the one or more correction application attributes indicating a manner of applying one or more display misalignment correction operations to align presentation of content in the stereoscopic display system, and (iii) apply the one or more display misalignment correction operations to align the presentation of the content in the stereoscopic display system in accordance with the one or more correction application attributes, thereby effectuating display misalignment correction in a manner that mitigates user discomfort.

Abstract: A computer-implemented method is provided of controlling operation of an indoor fan in an air conditioning system, the method including: setting a fan speed of the indoor fan to a maximum value; storing a first low temperature as a low temperature threshold; measuring the indoor temperature in an indoor space as a current indoor temperature; subtracting a set point temperature from the current indoor temperature to determine a temperature difference; determining that the temperature difference is less than the low temperature threshold; and reducing the fan speed by a first adjustment interval, storing a second low temperature difference as the low temperature threshold, and storing a second high temperature as a high temperature threshold, all in response to the determining that the current temperature difference is less than the low temperature threshold.

Abstract: A system and method of using an O-ring retaining apparatus to maintain an O-ring in the same position relative to the position of the handle of a bar gun while permitting a valve stem in physical contact with the O-ring to slide past without the O-ring becoming dislodged.

Abstract: Methods and formulations are provided for treating spinobulbar muscular atrophy in a subject in need thereof. By administering a therapeutically effective amount of a selective androgen receptor modulator or a small molecule such as 1-[2-(4-methylphenoxy)ethyl]-2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole or a derivative, prodrug, or pharmaceutically acceptable salt thereof, one or more symptoms of spinobulbar muscular atrophy can be ameliorated. The effective amount can be effective to prevent or delay loss of body weight, a loss of mobility, and/or a loss of physical strength in the subject; to prevent or delay neurogenic atrophy and/or to prevent a loss of spinal cord motor neurons in the subject; to restore the frequency of type I myofibers to normal levels for a healthy subject; and/or to reverse testicular atrophy in the subject.