Abstract: A tailgate assembly includes a frame subassembly having a cargo bed access opening disposed between a driver side section and a passenger side section, and a door subassembly that is pivotably coupled to the frame subassembly. The door subassembly is pivotable relative to the frame subassembly back-and-forth between a door open position and a door closed position. The door subassembly closes the cargo bed access opening when the door subassembly is in the door closed position. The tailgate assembly further includes an actuator system that can pivot the door subassembly and the frame subassembly together back-and-forth between a tailgate closed position and a tailgate open position.

Abstract: A light-emitting system (1000) removably attachable to headgear is provided, which comprises: a form factor (1010) configured to surround a portion of the headgear when the light-emitting system (1000) is removably attached to the headgear for use; a plurality of halo lighting elements (1100) configured to selectively generate at least a partial halo of light that radiates outwardly away from the light-emitting system; and at least one task lighting element (1120) aligned in a direction along a task light axis (1130) that is fixed and oriented downwardly at an oblique angle (?) relative to a transverse plane (TP) of the light-emitting system (1000), the at least one task lighting element (1120) being configured to selectively generate flood task lighting in an area in front of a user.

Abstract: Hinge systems are provided for movably mounting a door subassembly to a tailgate assembly of a motor vehicle. An exemplary hinge system may include an upper hinge assembly and a lower hinge assembly. Each hinge assembly may include a gooseneck bracket that establishes a load path through the respective hinge assembly. The load path through the upper hinge assembly may be configured differently than the load path through the lower hinge assembly. The gooseneck brackets may be reinforced along the load paths in order to transfer stress loads through the stiffest portions of the gooseneck brackets during door loading events.

Abstract: A tailgate subassembly alignment method includes positioning at least one panel support bracket of a frame subassembly relative to a connection member of the frame subassembly, and securing the at least one panel support bracket to the connection member when the at least one panel support bracket is in a preset position. After securing the at least one panel support bracket, the method includes securing a tailgate panel assembly to the at least one panel support bracket.

Abstract: A tailgate assembly, includes a frame subassembly having a cargo bed access opening between a driver side section and a passenger side section, and a door subassembly that is pivotably coupled to the frame subassembly. The door subassembly is pivotable relative to the frame subassembly back-and-forth between a door open position and a door closed position. The door subassembly closes the cargo bed access opening when the door subassembly is in the door closed position. A latching system has a latch that engages a striker to hold the door subassembly in the door closed position. The tailgate assembly further includes an alignment system separate from the latching system. The alignment system includes an alignment post that is received within an alignment slot as the door subassembly is pivoted to the door closed position. The alignment post is configured to be received within the alignment slot to align the door subassembly relative to the frame subassembly prior to the latch contacting the striker.

Abstract: Vehicle systems for accessing and utilizing vehicle cargo spaces on vehicles equipped with a tailgate assembly having a door subassembly may include deployable step systems, deployable lift panel systems, deployable cargo extender systems, etc. The vehicle systems may be either separate from or integrated with the door subassembly of the tailgate assembly. An exemplary vehicle system may include a deployable step that is movable between a stowed position and a deployed position in order to present a step surface to a user for accessing the vehicle cargo space.

Abstract: A strapping tool is disclosed herein. In one or more embodiments, the strapping tool includes an external power source; a drivetrain assembly operatively coupled to the external power source; a sealing assembly, the sealing assembly comprising at least one jaw member, the drivetrain assembly operatively coupling the at least one jaw member to the external power source, and the at least one jaw member of the sealing assembly configured to crimp or notch a strapping seal member so as to secure a piece of strapping around a package or bundle of items. In these one or more embodiments, the drivetrain assembly is configured to return the at least one jaw member to an open position without sending or receiving a control signal from a control board.

Abstract: The tailgate assembly method includes presetting a frame subassembly of a tailgate assembly relative to a vehicle structure; and presetting a door subassembly of the tailgate assembly relative to the frame subassembly. The frame subassembly can include a cargo bed access opening between a driver side section and a passenger side section. The door subassembly can be pivotable relative to the frame subassembly back-and-forth between a door open position and a door closed position. The door subassembly closes the cargo bed access opening when the door subassembly is in the door closed position.

Abstract: Colorectal cancer (CRC) is often accompanied by cachexia, a multi-organ wasting syndrome which compromises musculoskeletal health. The disclosure is directed to the discovery that elevated levels of insulin-like growth factor binding protein 1 (IGFBP1) associated with cancers such as colorectal cancer (CRC) does not result from direct production of IGFBP1 by cancer cells. Methods and compositions to prevent or reduce the effects of cachexia are provided wherein a subject at risk of cachexia is administered a pharmaceutical composition comprising an inhibitor of IGFBP1.

Abstract: An online system receives a request from a user to access an ordering interface for a retailer and identifies a retailer location based on the user's location. The system uses a machine learning model to predict availabilities of items at the retailer location and identifies anchor items the user previously ordered from the retailer that are likely available. The system computes a first score for each anchor item based on an expected value associated with it and/or a likelihood the user will re-order it, determines categories associated with the anchor items, and ranks the categories based on the first score. For each category, the system identifies associated candidate items likely to be available and ranks them based on a second score for each candidate item computed based on a probability of user satisfaction with it as an anchor item replacement. The ordering interface is then generated based on the rankings.

Abstract: Techniques described herein relate to analyzing data systems to detect data deficiencies and generating user interfaces for performing user communication sessions to resolve the data deficiencies. A data system may include components and implement operations to analyze a related set of data to determine when to initiate a communication session with a user to resolve a data deficiency. The data system also may be configured to generate user interfaces customized based on particular users and/or particular associates to allow the associate to interact with the user to resolve the data deficiency. The data system also may determine when to record the communication session, store and/or transcribe the communication session, and/or associate the stored communication session records with the corresponding data in the data system.

Abstract: An online system generates a knowledge graph database representing relationships between entities in the online system. The online system generates the knowledge graph database by at least obtaining descriptions for an item. The online system generates one or more prompts to a machine-learned language model, where a prompt includes a request to extract a set of attributes for the item from the description of the item. The online system receives a response generated from executing the machine-learned language model on the prompts. The online system parses the response to extract the set of attributes for the item. For each extracted attribute, the online system generates connections between an item node representing the item and a set of attribute nodes for the extracted set of attributes in the database.

Abstract: A system, for example, an online system uses a machine learning based language model, for example, a large language model (LLM) to process high-level natural language queries received from users. The system receives a natural language query from a user of a client device. The system determines contextual information associated with the query. Based on this information, the system generates a prompt for the machine learning based language model. The system receives a response from the machine learning based language model. The system uses the response to generate a search query for a database. The system obtains results returned by the database in response to the search query and provides them to the user. The system allows users to specify high level natural language queries to obtain relevant search results, thereby improving the overall user experience.

Abstract: A strapping tool and a pump used thereby are disclosed herein. The strapping tool includes a battery-powered motor; a hydraulic assembly operatively coupled to the battery-powered motor; and a sealing assembly, the sealing assembly comprising at least one crimping jaw member, the hydraulic assembly operatively coupling the at least one crimping jaw member to the battery-powered motor, and the at least one crimping jaw member of the sealing assembly configured to crimp or notch a strapping seal member so as to secure a piece of strapping around a package or bundle of items. The pump includes a pump rotor; and a plurality of balls displaced by the pump rotor, the plurality of balls configured to displace a fluid in the pump. The pump contains no linkage members and no piston.

Abstract: A strapping tensioning and sealing tool is disclosed herein. In one or more embodiments, the strapping tensioning and sealing tool includes a tensioning assembly, the tensioning assembly configured to apply tension to a piece of strapping; and a sealing assembly, the sealing assembly comprising at least one cam member, at least one crimping jaw member, and a motive power source, the at least one cam member operatively coupling the at least one crimping jaw member to the motive power source, and the at least one crimping jaw member of the sealing assembly configured to crimp a strapping sealing member so as to secure the piece of strapping around a package or bundle of items.

Abstract: Vehicle systems for accessing and utilizing vehicle cargo spaces on vehicles equipped with a tailgate assembly having a door subassembly may include deployable step systems, deployable lift panel systems, deployable cargo extender systems, etc. The vehicle systems may be either separate from or integrated with the door subassembly of the tailgate assembly. An exemplary vehicle system may include a deployable step that is movable between a stowed position and a deployed position in order to present a step surface to a user for accessing the vehicle cargo space.

Abstract: An orthopedic instrument, comprising a pair of pivotally-connected arms, extending beyond a pivot axis of a first pivot; a pair of feet mounted to ends of the pair of pivotally-connected arms; and a quadrilateral linkage configured to maintain parallelism between the pair of feet over a range of angles and to selectively alter a distance between the pair of feet.

Abstract: The present invention relates to compounds of Formula I as defined herein, and salts and solvates thereof. (I) The present invention also relates to pharmaceutical compositions comprising compounds of Formula (I), and to compounds of Formula (I) for use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which inhibition of a RAS-effector protein-protein interaction is implicated.