Patents by Inventor Joshua T. Smith

Joshua T. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200016595
    Abstract: Techniques relate to forming a sorting device. A mesh is formed on top of a substrate. Metal assisted chemical etching is performed to remove substrate material of the substrate at locations of the mesh. Pillars are formed in the substrate by removal of the substrate material. The mesh is removed to leave the pillars in a nanopillar array. The pillars in the nanopillar array are designed with a spacing to sort particles of different sizes such that the particles at or above a predetermined dimension are sorted in a first direction and the particles below the predetermined dimension are sorted in a second direction.
    Type: Application
    Filed: September 25, 2019
    Publication date: January 16, 2020
    Inventors: Huan Hu, Joshua T. Smith, Gustavo A. Stolovitzky, Benjamin H. Wunsch
  • Publication number: 20200016596
    Abstract: Techniques relate to forming a sorting device. A mesh is formed on top of a substrate. Metal assisted chemical etching is performed to remove substrate material of the substrate at locations of the mesh. Pillars are formed in the substrate by removal of the substrate material. The mesh is removed to leave the pillars in a nanopillar array. The pillars in the nanopillar array are designed with a spacing to sort particles of different sizes such that the particles at or above a predetermined dimension are sorted in a first direction and the particles below the predetermined dimension are sorted in a second direction.
    Type: Application
    Filed: September 25, 2019
    Publication date: January 16, 2020
    Inventors: Huan Hu, Joshua T. Smith, Gustavo A. Stolovitzky, Benjamin H. Wunsch
  • Publication number: 20190388891
    Abstract: A technique relates to a machine for sorting. A removable cartridge includes a nanofluidic module. The removable cartridge includes an input port and at least two output ports. The nanofluidic module is configured to sort a sample fluid. A holder is configured to receive the removable cartridge. A pressurization system is configured to couple to the input port of the removable cartridge. The pressurization system is configured to drive the sample fluid into the nanofluidic module for separation to the at least two output ports.
    Type: Application
    Filed: September 4, 2019
    Publication date: December 26, 2019
    Inventors: Huan Hu, Michael A. Pereira, Joshua T. Smith, Benjamin H. Wunsch
  • Publication number: 20190382821
    Abstract: Techniques regarding screening for mutations using nanoscale deterministic arrays are provided. For example, one or more embodiments described herein can comprise a method, which can comprise cleaving a deoxyribonucleic acid segment hybridized with a molecular probe to form a sample fluid. The cleaving can occur at a first end and a second end of the molecular probe. Also, the cleaving can comprise a cleaving agent that targets base pair mismatches. The method can also comprise supplying the sample fluid to a nanoscale deterministic lateral displacement array to screen for a single nucleotide polymorphism.
    Type: Application
    Filed: June 13, 2018
    Publication date: December 19, 2019
    Inventors: Stacey Gifford, Benjamin Wunsch, Joshua T. Smith, Sung-Cheol Kim
  • Publication number: 20190381505
    Abstract: Multistage deterministic lateral displacement devices, methods of forming the devices, and methods of separating a fluid mixture including particles having three or more particle sizes generally include a first module and at least one additional module. Each module includes a condenser portion and a separate portion. The condenser portion is generally configured to focus a streamline of all particles to a center of a channel whereas the separator separates the streamline of all particles into two different streamlines. One of the streamlines focuses the largest particles in the fluid mixture along a sidewall of the channel and the other streamline of smaller particles is between opposing sidewalls that define the channel. Each additional module can be used to further separate the largest particles remaining in the fluid mixture from the smaller particles.
    Type: Application
    Filed: June 13, 2018
    Publication date: December 19, 2019
    Inventors: Sung-Cheol Kim, Stacey Gifford, Joshua T. Smith, Benjamin Wunsch
  • Publication number: 20190382828
    Abstract: Techniques regarding detecting one or more defined nucleic acid sequences are provided. For example, one or more embodiments described herein can comprise a method, which can comprise adding a molecular probe to a sample fluid comprising a first deoxyribonucleic acid segment and a second deoxyribonucleic acid segment. The molecular probe can have an affinity to bond to a defined nucleic acid sequence. The method can also comprise separating, via a nanoscale deterministic lateral displacement array, the first deoxyribonucleic acid segment from the second deoxyribonucleic acid segment based on a size of the first deoxyribonucleic acid segment.
    Type: Application
    Filed: June 13, 2018
    Publication date: December 19, 2019
    Inventors: Stacey Gifford, Sung-Cheol Kim, Joshua T. Smith, Benjamin Wunsch
  • Patent number: 10507466
    Abstract: Techniques relate to forming a sorting device. A mesh is formed on top of a substrate. Metal assisted chemical etching is performed to remove substrate material of the substrate at locations of the mesh. Pillars are formed in the substrate by removal of the substrate material. The mesh is removed to leave the pillars in a nanopillar array. The pillars in the nanopillar array are designed with a spacing to sort particles of different sizes such that the particles at or above a predetermined dimension are sorted in a first direction and the particles below the predetermined dimension are sorted in a second direction.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: December 17, 2019
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Huan Hu, Joshua T. Smith, Gustavo A. Stolovitzky, Benjamin H. Wunsch
  • Patent number: 10471425
    Abstract: A technique relates to a machine for sorting. A removable cartridge includes a nanofluidic module. The removable cartridge includes an input port and at least two output ports. The nanofluidic module is configured to sort a sample fluid. A holder is configured to receive the removable cartridge. A pressurization system is configured to couple to the input port of the removable cartridge. The pressurization system is configured to drive the sample fluid into the nanofluidic module for separation to the at least two output ports.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: November 12, 2019
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Huan Hu, Michael A. Pereira, Joshua T. Smith, Benjamin H. Wunsch
  • Publication number: 20190299827
    Abstract: Composite components (22, 32) are described herein. An example composite component (22, 32) includes a fill material sandwiched between a first shell and a second shell. The first shell can include a cavity for receiving the fill material. The second shell can include a recessed portion extending into the cavity. The recessed portion can be configured to receive a separate component (16a, 30) of a passenger seat (12).
    Type: Application
    Filed: July 7, 2016
    Publication date: October 3, 2019
    Applicant: Safran Seats USA LLC
    Inventors: Marc W. Kinard, Joshua T. Smith
  • Publication number: 20190299208
    Abstract: A technique relates to a fluidic cell configured to hold a nanofluidic chip. A first plate is configured to hold the nanofluidic chip. A second plate is configured to fit on top of the first plate, such that the nanofluidic chip is held in place. The second plate has at least one first port and at least one second port. The second plate has an entrance hole configured to communicate with an inlet hole of the nanofluidic chip. The second port is angled above the first port, such that the first port and second port intersect to form a junction. The second port is formed to have a line-of-sight to the entrance hole, such that the second port is configured to receive input for extracting air trapped at a vicinity of the entrance hole.
    Type: Application
    Filed: May 31, 2019
    Publication date: October 3, 2019
    Inventors: Michael A. Pereira, Joshua T. Smith, Benjamin H. Wunsch
  • Publication number: 20190287385
    Abstract: According to the present disclosure, devices, systems, and methods for locating, tracking, and conducting communications between care devices and networks of care facilities through local communications hubs.
    Type: Application
    Filed: June 7, 2019
    Publication date: September 19, 2019
    Inventors: Stephen R. Embree, Frederick C. Davidson, Theophile R. Lerebours, Phillip Maloney, Bruno J. Filliat, David M. Girardeau, Christian Saucier, Kelly F. Walton, Joshua P. Lingenfelser, Benjamin E. Howell, Bradley T. Smith, Laura A. Hassey, Stephen N. Moore, Britten J. Pipher
  • Patent number: 10391486
    Abstract: A technique relates to a fluidic cell configured to hold a nanofluidic chip. A first plate is configured to hold the nanofluidic chip. A second plate is configured to fit on top of the first plate, such that the nanofluidic chip is held in place. The second plate has at least one first port and at least one second port. The second plate has an entrance hole configured to communicate with an inlet hole of the nanofluidic chip. The second port is angled above the first port, such that the first port and second port intersect to form a junction. The second port is formed to have a line-of-sight to the entrance hole, such that the second port is configured to receive input for extracting air trapped at a vicinity of the entrance hole.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: August 27, 2019
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Michael A. Pereira, Joshua T. Smith, Benjamin H. Wunsch
  • Patent number: 10393642
    Abstract: A technique related to sorting entities is provided. An inlet is configured to receive a fluid, and an outlet is configured to exit the fluid. A nanopillar array, connected to the inlet and the outlet, is configured to allow the fluid to flow from the inlet to the outlet. The nanopillar array includes nanopillars arranged to separate entities by size. The nanopillars are arranged to have a gap separating one nanopillar from another nanopillar. The gap is constructed to be in a nanoscale range.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: August 27, 2019
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Yann A. Astier, Robert L. Bruce, Joshua T. Smith, Chao Wang, Benjamin H. Wunsch
  • Publication number: 20190224677
    Abstract: Microfluid chips that comprise one or more microscale and/or mesoscale condenser arrays, which can facilitate particle purification and/or fractionation, are described herein. In one embodiment, an apparatus can comprise a layer of a microfluidic chip. The layer can comprise an inlet that can receive fluid, an outlet that can output a purified version of the fluid, and a condenser array coupled between and in fluid communication with the inlet and the outlet. The condenser array can comprise a plurality of pillars arranged in a plurality of columns. Also, a pillar gap sized to facilitate a throughput rate of the fluid of greater than or equal to about 1.0 nanoliter per hour can be located between a first pillar of the plurality of pillars in a first column of the plurality of columns and a second pillar of the plurality of pillars in the first column.
    Type: Application
    Filed: January 19, 2018
    Publication date: July 25, 2019
    Inventors: Joshua T. Smith, Stacey M. Gifford, Sung-Cheol Kim, Benjamin H. Wunsch
  • Publication number: 20190226953
    Abstract: Microscale and/or mesoscale condenser arrays that can facilitate microfluidic separation and/or purification of mesoscale and/or nanoscale particles and methods of operation are described herein. An apparatus comprises a condenser array comprising pillars arranged in a plurality of columns, wherein a pillar gap greater than or equal to about 0.5 micrometers is located between a first pillar of the pillars in a first column of the columns and a second pillar of the plurality of pillars in the first column, and wherein the first pillar is adjacent to the second pillar. The first ratio can be characterized by Dx/Dy is less than or equal to a first defined value, wherein Dx represents a first distance across the lattice in a first direction, wherein Dy represents a second distance across the lattice in a second direction, and wherein the first direction is orthogonal to the second direction.
    Type: Application
    Filed: January 19, 2018
    Publication date: July 25, 2019
    Inventors: Benjamin H. Wunsch, Joshua T. Smith, Sung-Cheol Kim, Stacey M. Gifford
  • Publication number: 20190224679
    Abstract: Microfluidic chips that can comprise thin substrates and/or a high density of vias are described herein. An apparatus comprises: a silicon device layer comprising a plurality of vias, the plurality of vias comprising greater than or equal to about 100 vias per square centimeter of a surface of the silicon device layer and less than or equal to about 100,000 vias per square centimeter of the surface of the silicon device layer, and the plurality of vias extending through the silicon device layer; and a sealing layer bonded to the silicon device layer, wherein the sealing layer has greater rigidity than the silicon device layer. In some embodiments, the silicon device layer has a thickness between about 7 micrometers and about 500 micrometers while a via of the plurality of vias has a diameter between about 5 micrometers and about 5 millimeters.
    Type: Application
    Filed: January 19, 2018
    Publication date: July 25, 2019
    Inventors: Joshua T. Smith, William Francis Landers, Kevin Winstel, Teresa Jacqueline Wu
  • Patent number: 10360787
    Abstract: According to the present disclosure, devices, systems, and methods for locating, tracking, and conducting communications between care devices and networks of care facilities through local communications hubs.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: July 23, 2019
    Assignee: Hill-Rom Services, Inc.
    Inventors: Stephen R. Embree, Frederick C. Davidson, Theophile R. Lerebours, Phillip Maloney, Bruno J. Filliat, David M. Girardeau, Christian Saucier, Kelly F. Walton, Joshua P. Lingenfelser, Benjamin E. Howell, Bradley T. Smith, Laura A. Hassey, Stephen N. Moore, Britten J. Pipher
  • Patent number: 10349653
    Abstract: The present disclosure relates to methods for forming an antimicrobial nanostructure and antimicrobial articles. The methods may include: providing a master template of a layout of the antimicrobial nanostructure on a silicon substrate, depositing a silicon nitride layer on a top surface of the silicon substrate, forming a patterned lithographic resist mask layer on a top surface of the silicon nitride layer, generating certain silicon pillars according to the patterned lithographic resist mask using a resist and reactive ion etching, forming certain lateral silicon nanospikes on the silicon pillars by performing metal assisted chemical etching (MacEtch), and removing the silicon nitride layer and bonding a top cover glass on the silicon pillars to form the antimicrobial nanostructure having lateral silicon nanospikes.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: July 16, 2019
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stacey M. Gifford, Huan Hu, Pablo Meyer Rojas, Joshua T. Smith
  • Publication number: 20190153516
    Abstract: A technique relates to separation of a mixture. A nano-deterministic lateral displacement (nanoDLD) array is configured to separate the mixture in a fluid. A feedback system is configured to control a velocity of the fluid through the nanoDLD array. The feedback system is configured to control the velocity of the fluid to separate one or more entities in the mixture.
    Type: Application
    Filed: January 22, 2019
    Publication date: May 23, 2019
    Inventors: Stacey M. Gifford, Joshua T. Smith, Benjamin H. Wunsch
  • Patent number: 10253350
    Abstract: A technique relates to separation of a mixture. A nano-deterministic lateral displacement (nanoDLD) array is configured to separate the mixture in a fluid. A feedback system is configured to control a velocity of the fluid through the nanoDLD array. The feedback system is configured to control the velocity of the fluid to separate one or more entities in the mixture.
    Type: Grant
    Filed: September 20, 2016
    Date of Patent: April 9, 2019
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Stacey M. Gifford, Joshua T. Smith, Benjamin H. Wunsch