Patents by Inventor Jun Pan

Jun Pan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROCYCLIC COMPOUNDS AND USES THEREOF
    Publication number: 20180244627
    Abstract: The present disclosure relates to heterocyclic compounds, and pharmaceutical compositions of the same, that are modulators/inhibitors of HDACs, such as HDAC8 and are useful in the treatment of HDAC-associated diseases.
    Type: Application
    Filed: August 12, 2016
    Publication date: August 30, 2018
    Inventors: Jun Pan, Xiaozhao Wang, Joseph Barbosa, Wenqing Yao, Yingda Ye
  • Pyrrolopyrimidine derivatives as TAM inhibitors
    Patent number: 10053465
    Abstract: This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: August 21, 2018
    Assignee: Incyte Corporation
    Inventors: Yun-Long Li, David M. Burns, Hao Feng, Joseph Glenn, Chunhong He, Taisheng Huang, Song Mei, Jun Pan, Xiaozhao Wang, Yingda Ye
  • PYRAZOLOPYRIDINE COMPOUNDS AND USES THEREOF
    Publication number: 20180228786
    Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer.
    Type: Application
    Filed: February 14, 2018
    Publication date: August 16, 2018
    Inventors: Alexander Sokolsky, Oleg Vechorkin, Kai Liu, Jun Pan, Wenqing Yao, Qinda Ye
  • METHOD FOR REAL-TIME CUTTING OF DIGITAL ORGAN BASED ON METABALL MODEL AND HYBRID DRIVING METHOD
    Publication number: 20180204378
    Abstract: Disclosed is a method for real-time cutting of digital organ based on a metaball model and a hybrid driving method, including a cutting procedure for driving a model using a position-based dynamics and a meshless method, a cutting mode which begins from a metaball driven by the position-based dynamics, proceeds to a point set driven by the meshless method and then create a new metaball. The method includes: a preprocessing procedure which performs an initialization operation while reading a model file; a deforming procedure which drives a model using a method based on the position-based dynamics; a cutting procedure which drives the model using the hybrid driving method and performs cutting using said cutting mode; and a rendering procedure which renders the model during the second and third procedures.
    Type: Application
    Filed: December 7, 2017
    Publication date: July 19, 2018
    Inventors: JUN PAN, SHIZENG YAN, QINPING ZHAO
  • THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS
    Publication number: 20180193323
    Abstract: The present disclosure describes thiazole and pyridine carboxamide derivatives, their compositions and methods of use. The compounds inhibit the activity of the Pim kinases and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Application
    Filed: November 16, 2017
    Publication date: July 12, 2018
    Inventors: Chu-Biao Xue, Yun-Long Li, Hao Feng, Jun Pan, Anlai Wang, Ke Zhang, Wenqing Yao, Fenglei Zhang, Jincong Zhuo
  • Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors
    Patent number: 10000507
    Abstract: The present disclosure describes furo- and thieno-pyridine carboxamide compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: June 19, 2018
    Assignee: Incyte Corporation
    Inventors: Yun-Long Li, David M. Burns, Hao Feng, Taisheng Huang, Song Mei, Jun Pan, Hai-Fen Ye, Wenyu Zhu, Maria Rafalski, Anlai Wang, Chu-Biao Xue
  • PYRAZOLOPYRIDONE COMPOUNDS AND USES THEREOF
    Publication number: 20180072719
    Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer.
    Type: Application
    Filed: September 8, 2017
    Publication date: March 15, 2018
    Inventors: Qinda Ye, Kai Liu, Jun Pan, Alexander Sokolsky, Oleg Vechorkin, Wenqing Yao
  • PYRAZOLOPYRIDINE COMPOUNDS AND USES THEREOF
    Publication number: 20180072720
    Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer.
    Type: Application
    Filed: September 8, 2017
    Publication date: March 15, 2018
    Inventors: Oleg Vechorkin, Jun Pan, Kai Liu, Alexander Sokolsky, Anlai Wang, Hai Fen Ye, Qinda Ye, Wenqing Yao
  • PYRAZOLOPYRIDINE COMPOUNDS AND USES THEREOF
    Publication number: 20180072718
    Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer.
    Type: Application
    Filed: September 8, 2017
    Publication date: March 15, 2018
    Inventors: Kai Liu, Jun Pan, Alexander Sokolsky, Oleg Vechorkin, Hai Fen Ye, Qinda Ye, Wenqing Yao
  • PYRAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF
    Publication number: 20180072741
    Abstract: Disclosed are compounds of Formula (I), methods of using the compounds for inhibiting HPK1 activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer.
    Type: Application
    Filed: September 8, 2017
    Publication date: March 15, 2018
    Inventors: Oleg Vechorkin, Kai Liu, Jun Pan, Alexander Sokolsky, Hai Fen Ye, Qinda Ye, Wenqing Yao, Joshua Hummel
  • Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors
    Patent number: 9890162
    Abstract: The present disclosure describes bicyclic aromatic carboxamide derivatives, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: February 13, 2018
    Assignee: Incyte Corporation
    Inventors: Yaping Sun, Hao Feng, Yun-Long Li, Song Mei, Jun Pan, Anlai Wang, Hai-Fen Ye, Ke Zhang
  • DUSTING DEVICE FOR CLEANING MACHINE
    Publication number: 20170290487
    Abstract: A dusting device for a cleaning machine, being capable of detachably assembled to a bottom of the cleaning machine, includes at least a first rotary disc, a second rotary disc, an idler pulley, a driving rope unit, and dusting elements respectively attached to the first and second rotary discs. The driving rope unit is movably disposed on the first rotary disc, the idler pulley, and the second rotary disc. The first rotary disc is driven to rotate by a motor installed in the cleaning machine, and the idle pulley is driven to rotate by the driving rope unit and the first rotary disc, so as to further drive the second rotary disc to rotate in conjunction with the first rotary disc, whereby enabling the dusting elements to rotate to dust and clean a surface to be cleaned.
    Type: Application
    Filed: April 12, 2016
    Publication date: October 12, 2017
    Inventors: YA-Ching YANG, Yi-Jun Pan, Pai-Yung Lin
  • BICYCLIC AROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS
    Publication number: 20170253587
    Abstract: The present disclosure describes bicyclic aromatic carboxamide derivatives, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Application
    Filed: January 13, 2017
    Publication date: September 7, 2017
    Inventors: Yaping Sun, Hao Feng, Yun-Long Li, Song Mei, Jun Pan, Anlai Wang, Hai-Fen Ye, Ke Zhang
  • Method and device for determining position
    Patent number: 9706347
    Abstract: The present disclosure provides a method and a terminal for determining a position. The method includes detecting a position request of a designated application and acquiring a position coordinate of the terminal through a positioning function. The method also includes determining a designated region to which the position coordinate belongs, in pre-stored correspondence relationships between position coordinate ranges and designated regions. The method further includes responding to the position request of the designated application according to the designated region to which the position coordinate belongs.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: July 11, 2017
    Assignee: Xiaomi Inc.
    Inventors: Jun Pan, Yuheng Qi, Dailin Jiang
  • FURO- AND THIENO-PYRIDINE CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS
    Publication number: 20170190716
    Abstract: The present disclosure describes furo- and thieno-pyridine carboxamide compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Application
    Filed: December 15, 2016
    Publication date: July 6, 2017
    Inventors: Yun-Long Li, David M. Burns, Hao Feng, Taisheng Huang, Song Mei, Jun Pan, Oleg Vechorkin, Hai-Fen Ye, Wenyu Zhu, Maria Rafalski, Anlai Wang, Chu-Biao Xue
  • THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS
    Publication number: 20170182017
    Abstract: The present disclosure describes thiazole and pyridine carboxamide derivatives, their compositions and methods of use. The compounds inhibit the activity of the Pim kinases and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Application
    Filed: December 9, 2016
    Publication date: June 29, 2017
    Inventors: Chu-Biao Xue, Yun-Long Li, Hao Feng, Jun Pan, Anlai Wang, Ke Zhang, Wenqing Yao, Fenglei Zhang, Jincong Zhuo
  • Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors
    Patent number: 9676750
    Abstract: The present disclosure describes bicyclic aromatic carboxamide derivatives, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Grant
    Filed: January 20, 2016
    Date of Patent: June 13, 2017
    Assignees: Incyte Corporation, Incyte Holdings Corporation
    Inventors: Yun-Long Li, David M. Burns, Hao Feng, Chu-Biao Xue, Anlai Wang, Jun Pan
  • PYRROLOPYRIMIDINE DERIVATIVES AS TAM INHIBITORS
    Publication number: 20170057965
    Abstract: This application relates to compounds of Formula I: or pharmaceutically acceptable salts thereof, which are inhibitors of TAM kinases which are useful for the treatment of disorders such as cancer.
    Type: Application
    Filed: August 25, 2016
    Publication date: March 2, 2017
    Inventors: Yun-Long Li, David M. Burns, Hao Feng, Joseph Glenn, Chunhong He, Taisheng Huang, Song Mei, Jun Pan, Xiaozhao Wang, Yingda Ye
  • Dusting device
    Patent number: 9579007
    Abstract: A dusting device to be rotatably connected to the bottom of a cleaning machine or vacuum cleaner includes a rotary disc and a dusting element. The rotary disc includes a base and a connecting portion below the base. The connecting portion extends outward from the periphery of the base and has a bottom surface forming a pressing plate. The dusting element is detachably assembled to the connecting portion of the rotary disc in order to be pressed by the pressing plate. The dusting element includes at least one cleaning layer for contact with a surface to be cleaned so as to carry out dusting and cleaning.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: February 28, 2017
    Inventors: YA-Ching Yang, Yi-Jun Pan, Pai-Yung Lin
  • Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors
    Patent number: 9580418
    Abstract: The present disclosure describes bicyclic aromatic carboxamide derivatives, as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: February 28, 2017
    Assignee: Incyte Corporation
    Inventors: Yaping Sun, Hao Feng, Yun-Long Li, Song Mei, Jun Pan, Anlai Wang, Hai-Fen Ye, Ke Zhang