Abstract: Devices and methods for useful in providing localized synchronized and/or dynamic in-band internal gamma code adjustment per frame period are provided. By way of example, a display panel includes a data driver, which includes a first DAC configured to provide an internal gamma voltage signal to cause a first adjustment to an image data signal. The first adjustment is configured to selectively adjust the image data signal based at least in part on a refresh rate or a frame rate of the display panel. The data driver includes a second DAC coupled to the first DAC and configured to provide an external gamma voltage signal configured to provide a second adjustment to the image data signal, and an output buffer configured to supply the image data signal to pixels of the display panel, wherein the image data signal comprises the first adjustment and the second adjustment.

Abstract: An electronic device may include display layers such as liquid crystal display layers and a backlight unit that provides illumination for the display layers. The backlight unit may include light-emitting diodes that emit light into the edge of a light guide film. To minimize the inactive area of the display, the light-emitting diodes may be tightly spaced to approximate a line light source instead of point light sources. Color and/or luminance compensation layers may be incorporated at various locations within the backlight structures to ensure that the backlight provided to the display layers is homogenous. A thin-film transistor layer of the display may be coupled to a printed circuit board by a flexible printed circuit. The flexible printed circuit may have additional solder mask layers to improve robustness, may include encapsulation, and may have traces with a varying pitch.

Abstract: A system and method of optimizing tree pruning for a decision tree may include splitting, a first dataset into a training dataset and a testing dataset, growing the training dataset into a first decision tree, sampling the training dataset by creating a plurality of sampling datasets from the training dataset, pruning the first decision tree using the plurality of sampling datasets, creating a plurality of models, at least one for each of the plurality of sampling datasets, and verifying the accuracy of each of the plurality of models, using the testing dataset.

Abstract: The present disclosure provides compounds of any one of Formulae (I), (II), and (III). The compounds described herein are inhibitors of histone methyltransferases (e.g., enhancer of zeste homolog 1 (EZH1) and enhancer of zeste homolog 2 (EZH2)) and are useful in treating and/or preventing a broad range of diseases (e.g., proliferative diseases). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein.

Abstract: A glass production apparatus producing continuously curved glass for covers and containers includes a crucible, a calender device, a cutting device, a molding device, and a crystallizing device. The crucible melts glass raw material and outputs a glass melt to calender device. The calender device rolls and presses the glass melt to prepare a glass belt with a preset temperature. The cutting device cuts the glass belt with the preset temperature into glass members. The molding device include at least one molding mold and a manipulator. Each of the at least one molding mold curves at least one portion of the glass member with the preset temperature to prepare a curved glass member. The manipulator transfers the curved glass member to the crystallizing device, the crystallizing device crystallizes the curved glass member to prepare a curved crystalline glass member. A method for manufacturing such glass is also provided.

Abstract: A production apparatus making continuously curved crystalline glass as a cover or container includes a melting device, a drainage device, a molding device, and a crystallizing device. The melting device melts glass raw material to form a glass melt. The drainage device drains the glass melt to the molding device. The molding device includes a rotating table and a plurality of molding molds thereon. Each molding mold can be moved toward or away from the drainage device by the rotating table. Each molding mold has a molding cavity. At least one part of the molding cavity includes a plane, and at least one part of the molding cavity includes a curved surface to extrude the glass melt with such different surface forms. The crystallizing device crystallizes the curved glass member to achieve the curved crystallized glass member. A method for manufacturing such glass is also provided.

Abstract: A display may have a pixel array such as a liquid crystal pixel array. The pixel array may be illuminated with backlight illumination from a backlight unit. The backlight unit may include a printed circuit board, a plurality of light-emitting diodes mounted on the printed circuit board, at least one light spreading layer formed over the printed circuit board that spreads light received from the plurality of light-emitting diodes, a partially reflective layer formed over the at least one light spreading layer, a color conversion layer formed over the partially reflective layer, a collimating layer formed over the color conversion layer, a brightness enhancement film formed over the collimating layer, and a diffuser formed over the brightness enhancement film. The at least one light spreading layer may include two light spreading layers with elongated protrusions that are rotated relative to each other.

Abstract: Display structures for controlling viewing angle color shift are described. In various embodiments, polarization sensitive diffusers, independent controlled cathode thicknesses, filtermasks, touch detection layers, and color filters are described.

Abstract: Display structures for controlling viewing angle color shift are described. In various embodiments, polarization sensitive diffusers, independent controlled cathode thicknesses, filtermasks, and color filters are described.

Abstract: A display may have a pixel array such as a liquid crystal pixel array. The pixel array may be illuminated by a backlight unit that includes an array of light-emitting diodes. A backlight brightness selection circuit may select brightness values for the light-emitting diodes. The backlight brightness selection circuit may select the brightness values based on image data, based on brightness values used in previous image frames, based on device information, and/or based on sensor information. The backlight brightness selection circuit may select the backlight brightness levels to mitigate visible artifacts such as flickering and halo. The backlight levels selected by the backlight brightness selection may be modified by a power consumption compensation circuit. The power consumption compensation circuit may estimate the amount of power consumption required to operate the backlight using the target brightness levels and may modify the target brightness levels to meet maximum power consumption requirements.

Abstract: A backlight unit may include a turning film that receives light from a light guide layer. The turning film may have a plurality of elongated protrusions that extend across the turning film. Each protrusion may have a concave surface. The concave surface may be a curved surface that curves inward towards the interior of the turning film. Light from the light guide layer may pass through the turning film and be reflected towards a viewer by the concave surfaces of the protrusions. In a liquid crystal display, the turning film may be interposed between the light guide layer and a lower polarizer. In certain embodiments, the turning film may be the only optical layer interposed between the light guide layer and the lower polarizer. In other embodiments, the turning layer and a diffuser layer may be the only optical layers interposed between the light guide layer and the lower polarizer.

Abstract: An electronic device may have a display. Inactive portions of the display such as peripheral portions of the display may be masked using an opaque masking layer. An opening may be provided in the opaque masking layer to allow light to pass. For example, a logo may be viewed through an opening in the opaque masking layer and a camera may receive light through an opening in the opaque masking layer. The display may include upper and lower polarizers, a color filter layer, and a thin-film transistor layer. The opaque masking layer may be formed on the upper polarizer, may be interposed between the upper polarizer and the color filter layer, or may be interposed between the color filter layer and the thin-film transistor layer. The upper polarizer may have unpolarized windows for cameras, logos, or other internal structures.

Abstract: A privacy film may have a light-blocking layer that is interposed between first and second transparent substrates. The light-blocking layer may have a plurality of opaque portions and a plurality of transparent portions. The opaque portions may be shaped to ensure light from the display is directed only to the primary viewer of the display. Each opaque portion of the light-blocking layer may extend along a respective longitudinal axis between the first and second transparent substrates. Privacy films used to cover curved displays may have opaque portions that extend along longitudinal axes that have different angles relative to the transparent substrates. Opaque portions in the edge of the privacy film may have longitudinal axes that are at non-perpendicular angles with respect to the transparent substrates. A privacy film for a curved display may also include a light-redirecting layer such as a prism layer or a liquid crystal layer.

Abstract: The present disclosure provides compounds of any one of Formulae (I), (II), and (III). The compounds described herein are inhibitors of histone methyltransferases (e.g., enhancer of zeste homolog 1 (EZH1) and enhancer of zeste homolog 2 (EZH2)) and are useful in treating and/or preventing a broad range of diseases (e.g., proliferative diseases). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein.

Abstract: Provided herein are compounds useful as inhibitors of CBX. Also described are pharmaceutical compositions and medical uses of these compounds.

Abstract: A display may have a pixel array such as a liquid crystal pixel array. The pixel array may be illuminated with backlight illumination from a backlight unit. The backlight unit may include an array of light-emitting diodes and a light reflector that helps reflect light from the light-emitting diodes through the pixel array. A color conversion layer may be used to convert light from the light-emitting diodes from blue light to white light. A microlens array layer formed over the color conversion layer may spread the light from the color conversion layer to homogenize the light. To ensure light is emitted from the backlight with a uniform color, the microlens array layer may have different transmittance portions. A central portion of the microlens array layer may transmit more light and reflect less light than an edge portion of the microlens array layer.

Abstract: The present application relates to compounds comprising an ester, a thioester, or a hydrazide moiety and methods of synthesizing these compounds. The present application also relates to pharmaceutical compositions containing the compounds and methods of treating cell proliferative disorders mediated by the Hh signaling pathway, such as cancer, by administering the compounds and pharmaceutical compositions to subjects in need thereof.

Abstract: The invention relates to novel derivatives of thapsigargin that are chemically modified with a group that targets a cell surface-expressed receptor, and pharmaceutical preparations thereof. The invention further relates to methods of treating diseases such as cancer using the compounds of the invention.

Abstract: A system and method of optimizing tree pruning for a decision tree may include splitting, a first dataset into a training dataset and a testing dataset, growing the training dataset into a first decision tree, sampling the training dataset by creating a plurality of sampling datasets from the training dataset, pruning the first decision tree using the plurality of sampling datasets, creating a plurality of models, at least one for each of the plurality of sampling datasets, and verifying the accuracy of each of the plurality of models, using the testing dataset.

Abstract: The present application relates to compounds comprising an ester, a thioester, or a hydrazide moiety and methods of synthesizing these compounds. The present application also relates to pharmaceutical compositions containing the compounds and methods of treating cell proliferative disorders mediated by the Hh signaling pathway, such as cancer, by administering the compounds and pharmaceutical compositions to subjects in need thereof.